JP2016514150A5 - - Google Patents
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- Publication number
- JP2016514150A5 JP2016514150A5 JP2016501898A JP2016501898A JP2016514150A5 JP 2016514150 A5 JP2016514150 A5 JP 2016514150A5 JP 2016501898 A JP2016501898 A JP 2016501898A JP 2016501898 A JP2016501898 A JP 2016501898A JP 2016514150 A5 JP2016514150 A5 JP 2016514150A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- subject
- tissue
- acetylglucosamine
- composition according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims description 38
- 239000002121 nanofiber Substances 0.000 claims description 19
- 230000037303 wrinkles Effects 0.000 claims description 13
- 239000000835 fiber Substances 0.000 claims description 7
- 102000008186 Collagen Human genes 0.000 claims description 3
- 108010035532 Collagen Proteins 0.000 claims description 3
- 229920001436 collagen Polymers 0.000 claims description 3
- 102000016942 Elastin Human genes 0.000 claims description 2
- 108010014258 Elastin Proteins 0.000 claims description 2
- 229920002549 elastin Polymers 0.000 claims description 2
- 210000001519 tissue Anatomy 0.000 claims 15
- 229950006780 n-acetylglucosamine Drugs 0.000 claims 11
- OVRNDRQMDRJTHS-FMDGEEDCSA-N N-acetyl-beta-D-glucosamine Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O OVRNDRQMDRJTHS-FMDGEEDCSA-N 0.000 claims 8
- 238000002347 injection Methods 0.000 claims 8
- 239000007924 injection Substances 0.000 claims 8
- 238000011200 topical administration Methods 0.000 claims 4
- OVRNDRQMDRJTHS-UHFFFAOYSA-N N-acelyl-D-glucosamine Natural products CC(=O)NC1C(O)OC(CO)C(O)C1O OVRNDRQMDRJTHS-UHFFFAOYSA-N 0.000 claims 3
- MBLBDJOUHNCFQT-LXGUWJNJSA-N N-acetylglucosamine Natural products CC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO MBLBDJOUHNCFQT-LXGUWJNJSA-N 0.000 claims 3
- -1 N-acetylglucosamine monosaccharide Chemical class 0.000 claims 3
- 210000002889 endothelial cell Anatomy 0.000 claims 2
- 239000010408 film Substances 0.000 claims 2
- 238000002329 infrared spectrum Methods 0.000 claims 2
- 238000010255 intramuscular injection Methods 0.000 claims 2
- 239000007927 intramuscular injection Substances 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- 239000007921 spray Substances 0.000 claims 2
- 238000010254 subcutaneous injection Methods 0.000 claims 2
- 239000007929 subcutaneous injection Substances 0.000 claims 2
- 210000003606 umbilical vein Anatomy 0.000 claims 2
- 102000007469 Actins Human genes 0.000 claims 1
- 108010085238 Actins Proteins 0.000 claims 1
- 102000012422 Collagen Type I Human genes 0.000 claims 1
- 108010022452 Collagen Type I Proteins 0.000 claims 1
- 102000001187 Collagen Type III Human genes 0.000 claims 1
- 108010069502 Collagen Type III Proteins 0.000 claims 1
- 241000238424 Crustacea Species 0.000 claims 1
- 238000000134 MTT assay Methods 0.000 claims 1
- 231100000002 MTT assay Toxicity 0.000 claims 1
- GLNADSQYFUSGOU-GPTZEZBUSA-J Trypan blue Chemical compound [Na+].[Na+].[Na+].[Na+].C1=C(S([O-])(=O)=O)C=C2C=C(S([O-])(=O)=O)C(/N=N/C3=CC=C(C=C3C)C=3C=C(C(=CC=3)\N=N\C=3C(=CC4=CC(=CC(N)=C4C=3O)S([O-])(=O)=O)S([O-])(=O)=O)C)=C(O)C2=C1N GLNADSQYFUSGOU-GPTZEZBUSA-J 0.000 claims 1
- 230000006907 apoptotic process Effects 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 210000002808 connective tissue Anatomy 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 230000007717 exclusion Effects 0.000 claims 1
- 239000000945 filler Substances 0.000 claims 1
- 239000000499 gel Substances 0.000 claims 1
- 238000002513 implantation Methods 0.000 claims 1
- 238000007373 indentation Methods 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 238000007918 intramuscular administration Methods 0.000 claims 1
- 239000006193 liquid solution Substances 0.000 claims 1
- 230000037323 metabolic rate Effects 0.000 claims 1
- 210000002200 mouth mucosa Anatomy 0.000 claims 1
- 210000000651 myofibroblast Anatomy 0.000 claims 1
- 239000002674 ointment Substances 0.000 claims 1
- 239000006072 paste Substances 0.000 claims 1
- 239000000843 powder Substances 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
- 210000002460 smooth muscle Anatomy 0.000 claims 1
- 239000000725 suspension Substances 0.000 claims 1
- 210000003491 skin Anatomy 0.000 description 8
- 230000001815 facial effect Effects 0.000 description 2
- 210000000434 stratum corneum Anatomy 0.000 description 2
- 210000004207 dermis Anatomy 0.000 description 1
- 210000001061 forehead Anatomy 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 239000002105 nanoparticle Substances 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361784765P | 2013-03-14 | 2013-03-14 | |
| US61/784,765 | 2013-03-14 | ||
| PCT/US2014/025623 WO2014165302A1 (en) | 2013-03-14 | 2014-03-13 | Treatment of disease with poly-n-acetylglucosamine nanofibers |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016514150A JP2016514150A (ja) | 2016-05-19 |
| JP2016514150A5 true JP2016514150A5 (enExample) | 2018-05-10 |
| JP6532452B2 JP6532452B2 (ja) | 2019-06-19 |
Family
ID=51659125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016501898A Active JP6532452B2 (ja) | 2013-03-14 | 2014-03-13 | ポリ−ｎ−アセチルグルコサミンナノファイバーを有する疾患の処置 |
Country Status (10)
| Country | Link |
|---|---|
| US (4) | US20150024014A1 (enExample) |
| EP (2) | EP3494791B1 (enExample) |
| JP (1) | JP6532452B2 (enExample) |
| AU (1) | AU2014248454B2 (enExample) |
| CA (1) | CA2901617A1 (enExample) |
| ES (1) | ES2704681T3 (enExample) |
| IL (1) | IL240222B (enExample) |
| MX (1) | MX2015011418A (enExample) |
| NZ (2) | NZ729181A (enExample) |
| WO (1) | WO2014165302A1 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8871247B2 (en) | 2007-02-19 | 2014-10-28 | Marine Polymer Technologies, Inc. | Hemostatic compositions and therapeutic regimens |
| CA2796068C (en) | 2010-04-15 | 2022-07-19 | Marine Polymer Technologies, Inc. | Anti-bacterial applications of poly-n-acetylglucosamine nanofibers |
| MX356877B (es) | 2011-04-15 | 2018-06-19 | Marine Polymer Tech Inc | Tratamiento de enfermedades con nanofibras de poli-n-acetil-glucosamina. |
| JP2015048436A (ja) * | 2013-09-03 | 2015-03-16 | 公立大学法人福井県立大学 | 植物の耐病性を向上させる、生物由来キチン質含有物、その使用方法、及びその製造方法 |
| JP6815782B2 (ja) * | 2016-07-29 | 2021-01-20 | 小林製薬株式会社 | α−ＳＭＡ産生抑制剤 |
| KR102233530B1 (ko) * | 2018-11-22 | 2021-03-31 | (주)프로스테믹스 | 엑소좀 및 이의 다양한 용도 |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2193634A1 (en) | 1972-07-20 | 1974-02-22 | Du Pont | Polyimide semi-permeable membranes |
| JPS6297624A (ja) | 1985-10-24 | 1987-05-07 | イ−・アイ・デユポン・デ・ニモアス・アンド・カンパニ− | ガス分離法及びその膜 |
| US4705540A (en) | 1986-04-17 | 1987-11-10 | E. I. Du Pont De Nemours And Company | Polyimide gas separation membranes |
| US4717394A (en) | 1986-10-27 | 1988-01-05 | E. I. Du Pont De Nemours And Company | Polyimide gas separation membranes |
| US4717393A (en) | 1986-10-27 | 1988-01-05 | E. I. Du Pont De Nemours And Company | Polyimide gas separation membranes |
| US4912197A (en) | 1987-08-14 | 1990-03-27 | E. I. Du Pont De Nemours And Company | Highly soluble clear polyimides |
| US4880442A (en) | 1987-12-22 | 1989-11-14 | E. I. Du Pont De Nemours And Company | Polyimide gas separation membranes |
| US4863496A (en) | 1988-04-13 | 1989-09-05 | E. I. Du Pont De Nemours And Co. | Reactive posttreatment for gas separation membranes |
| US4851505A (en) | 1988-04-13 | 1989-07-25 | E. I. Du Pont De Nemours And Company | Highly soluble aromatic polyimides |
| US4935490A (en) | 1988-04-13 | 1990-06-19 | E. I. Dupont De Nemours And Company | Highly soluble aromatic polyimides |
| US4838900A (en) | 1988-04-13 | 1989-06-13 | E. I. Du Pont De Nemours And Company | Polyimide gas separation membranes |
| US4961539A (en) | 1989-08-01 | 1990-10-09 | Deem K Michael | Truck-mounted pallet chipper |
| DE4200080A1 (de) * | 1992-01-03 | 1993-09-30 | Reinmueller Johannes | Pharmazeutische Zusammensetzung zur Wund-, Narben- und Keloidbehandlung |
| US5624679A (en) | 1993-12-01 | 1997-04-29 | Marine Polymer Technologies, Inc. | Methods and compositions for poly-β-1-4-N-acetylglucosamine biological barriers |
| US5858350A (en) | 1993-12-01 | 1999-01-12 | Marine Polymer Technologies | Methods and compositions for poly-β-1→4-N-acetylglucosamine cell therapy system |
| US5686115A (en) | 1993-12-01 | 1997-11-11 | Marine Polymer Technologies, Inc. | Poly-β-1→4-N-acetylucosamine copolymer composition with collagen |
| US5622834A (en) | 1993-12-01 | 1997-04-22 | Marine Polymer Technologies, Inc. | Method of isolating poly-β-1-4-N-acetylglucosamine from microalgal culture |
| US7041657B2 (en) | 2001-02-12 | 2006-05-09 | Marine Polymer Technologies Inc. | Compositions and methods for modulation of vascular structure and/or function |
| US8277849B2 (en) * | 2006-01-19 | 2012-10-02 | Solazyme, Inc. | Microalgae-derived compositions for improving the health and appearance of skin |
| US8871247B2 (en) | 2007-02-19 | 2014-10-28 | Marine Polymer Technologies, Inc. | Hemostatic compositions and therapeutic regimens |
| CA2796068C (en) | 2010-04-15 | 2022-07-19 | Marine Polymer Technologies, Inc. | Anti-bacterial applications of poly-n-acetylglucosamine nanofibers |
| MX356877B (es) * | 2011-04-15 | 2018-06-19 | Marine Polymer Tech Inc | Tratamiento de enfermedades con nanofibras de poli-n-acetil-glucosamina. |
-
2014
- 2014-03-13 EP EP18199627.3A patent/EP3494791B1/en active Active
- 2014-03-13 ES ES14779109T patent/ES2704681T3/es active Active
- 2014-03-13 AU AU2014248454A patent/AU2014248454B2/en not_active Ceased
- 2014-03-13 CA CA2901617A patent/CA2901617A1/en not_active Abandoned
- 2014-03-13 EP EP14779109.9A patent/EP2968190B1/en active Active
- 2014-03-13 JP JP2016501898A patent/JP6532452B2/ja active Active
- 2014-03-13 NZ NZ729181A patent/NZ729181A/en not_active IP Right Cessation
- 2014-03-13 MX MX2015011418A patent/MX2015011418A/es active IP Right Grant
- 2014-03-13 US US14/210,054 patent/US20150024014A1/en not_active Abandoned
- 2014-03-13 WO PCT/US2014/025623 patent/WO2014165302A1/en not_active Ceased
- 2014-03-13 NZ NZ629513A patent/NZ629513A/en not_active IP Right Cessation
- 2014-03-13 US US14/775,578 patent/US20160030465A1/en not_active Abandoned
-
2015
- 2015-07-29 IL IL240222A patent/IL240222B/en active IP Right Grant
-
2017
- 2017-12-14 US US15/841,903 patent/US20180360868A1/en not_active Abandoned
-
2018
- 2018-03-15 US US15/922,765 patent/US20190060348A1/en not_active Abandoned
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