JP2016513704A - チロシンキナーゼ阻害薬の結晶形態物及びその塩 - Google Patents

チロシンキナーゼ阻害薬の結晶形態物及びその塩 Download PDF

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JP2016513704A
JP2016513704A JP2016502487A JP2016502487A JP2016513704A JP 2016513704 A JP2016513704 A JP 2016513704A JP 2016502487 A JP2016502487 A JP 2016502487A JP 2016502487 A JP2016502487 A JP 2016502487A JP 2016513704 A JP2016513704 A JP 2016513704A
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powder
ray diffraction
diffraction pattern
crystalline
cancer
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JP2016513704A5 (enExample
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ジェイ ジィー‐チャン ウー
ジェイ ジィー‐チャン ウー
リン ワン
リン ワン
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ムンディファーマ インターナショナル コーポレイション リミテッド
ムンディファーマ インターナショナル コーポレイション リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
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    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2016502487A 2013-03-15 2014-03-14 チロシンキナーゼ阻害薬の結晶形態物及びその塩 Pending JP2016513704A (ja)

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US201361801112P 2013-03-15 2013-03-15
US61/801,112 2013-03-15
PCT/US2014/027591 WO2014152663A1 (en) 2013-03-15 2014-03-14 Crystalline forms of tyrosine kinase inhibitors and their salts

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JP2016513704A5 JP2016513704A5 (enExample) 2017-04-13

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US (5) US8999992B2 (enExample)
EP (1) EP2970148A4 (enExample)
JP (1) JP2016513704A (enExample)
KR (1) KR20150142688A (enExample)
CN (1) CN105377821A (enExample)
AU (1) AU2014239254B2 (enExample)
BR (1) BR112015022631A2 (enExample)
CA (1) CA2904403A1 (enExample)
CL (1) CL2015002593A1 (enExample)
CR (1) CR20150560A (enExample)
EA (1) EA201591684A1 (enExample)
GT (1) GT201500292A (enExample)
HK (1) HK1220193A1 (enExample)
MX (1) MX2015012403A (enExample)
NI (1) NI201500139A (enExample)
PE (1) PE20151884A1 (enExample)
PH (1) PH12015502110A1 (enExample)
SG (2) SG10201707484UA (enExample)
SV (1) SV2015005074A (enExample)
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UA (1) UA116466C2 (enExample)
WO (1) WO2014152663A1 (enExample)
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WO2014152663A1 (en) 2014-09-25
BR112015022631A2 (pt) 2017-12-19
KR20150142688A (ko) 2015-12-22
US20150174124A1 (en) 2015-06-25
EA201591684A1 (ru) 2016-02-29
HK1220193A1 (zh) 2017-04-28
US20170001969A9 (en) 2017-01-05
US20180057469A1 (en) 2018-03-01
US10124002B2 (en) 2018-11-13
US8999992B2 (en) 2015-04-07
ZA201507154B (en) 2017-09-27
EP2970148A1 (en) 2016-01-20
GT201500292A (es) 2019-07-29
US20170105990A1 (en) 2017-04-20
NI201500139A (es) 2016-02-16
US20140275113A1 (en) 2014-09-18
US9388146B2 (en) 2016-07-12
US9718794B2 (en) 2017-08-01
UA116466C2 (uk) 2018-03-26
AU2014239254B2 (en) 2018-06-28
TN2015000407A1 (en) 2017-01-03
MX2015012403A (es) 2016-04-04
SV2015005074A (es) 2017-07-19
US20160002182A1 (en) 2016-01-07
EP2970148A4 (en) 2016-10-12
PH12015502110A1 (en) 2016-01-11
CN105377821A (zh) 2016-03-02
CR20150560A (es) 2016-08-31
AU2014239254A1 (en) 2015-10-15
SG10201707484UA (en) 2017-10-30
US9993473B2 (en) 2018-06-12
PE20151884A1 (es) 2016-01-08
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CA2904403A1 (en) 2014-09-25
CL2015002593A1 (es) 2016-08-19

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