JP2016512886A5 - - Google Patents
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- Publication number
- JP2016512886A5 JP2016512886A5 JP2016502964A JP2016502964A JP2016512886A5 JP 2016512886 A5 JP2016512886 A5 JP 2016512886A5 JP 2016502964 A JP2016502964 A JP 2016502964A JP 2016502964 A JP2016502964 A JP 2016502964A JP 2016512886 A5 JP2016512886 A5 JP 2016512886A5
- Authority
- JP
- Japan
- Prior art keywords
- liquid
- fluid
- interface region
- fluid interface
- flow
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007788 liquid Substances 0.000 claims 67
- 239000012530 fluid Substances 0.000 claims 43
- 238000000034 method Methods 0.000 claims 14
- 230000004858 capillary barrier Effects 0.000 claims 10
- 238000004458 analytical method Methods 0.000 claims 7
- 230000003993 interaction Effects 0.000 claims 7
- 230000005499 meniscus Effects 0.000 claims 4
- 102000004169 proteins and genes Human genes 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- 210000005239 tubule Anatomy 0.000 claims 3
- 239000004205 dimethyl polysiloxane Substances 0.000 claims 2
- 238000001962 electrophoresis Methods 0.000 claims 2
- 238000000605 extraction Methods 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 2
- 238000003908 quality control method Methods 0.000 claims 2
- 238000011002 quantification Methods 0.000 claims 2
- 238000000926 separation method Methods 0.000 claims 2
- 238000011144 upstream manufacturing Methods 0.000 claims 2
- 230000004888 barrier function Effects 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 230000005661 hydrophobic surface Effects 0.000 claims 1
- -1 polydimethylsiloxane Polymers 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361785255P | 2013-03-14 | 2013-03-14 | |
| US61/785,255 | 2013-03-14 | ||
| PCT/US2014/029017 WO2014153092A1 (en) | 2013-03-14 | 2014-03-14 | Capillary barriers for staged loading of microfluidic devices |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020037919A Division JP2020109413A (ja) | 2013-03-14 | 2020-03-05 | マイクロ流体デバイスの段階的ロードのための毛細管バリア |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016512886A JP2016512886A (ja) | 2016-05-09 |
| JP2016512886A5 true JP2016512886A5 (enExample) | 2017-06-22 |
| JP6673820B2 JP6673820B2 (ja) | 2020-03-25 |
Family
ID=51581416
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016502964A Active JP6673820B2 (ja) | 2013-03-14 | 2014-03-14 | マイクロ流体デバイスの段階的ロードのための毛細管バリア |
| JP2020037919A Pending JP2020109413A (ja) | 2013-03-14 | 2020-03-05 | マイクロ流体デバイスの段階的ロードのための毛細管バリア |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2020037919A Pending JP2020109413A (ja) | 2013-03-14 | 2020-03-05 | マイクロ流体デバイスの段階的ロードのための毛細管バリア |
Country Status (8)
| Country | Link |
|---|---|
| US (6) | US20160160208A1 (enExample) |
| EP (1) | EP2972185A4 (enExample) |
| JP (2) | JP6673820B2 (enExample) |
| CN (2) | CN110243637B (enExample) |
| AU (4) | AU2014236262A1 (enExample) |
| CA (1) | CA2906730C (enExample) |
| GB (1) | GB2526999B (enExample) |
| WO (1) | WO2014153092A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2505706A (en) * | 2012-09-10 | 2014-03-12 | Univ Leiden | Apparatus comprising meniscus alignment barriers |
| JP6673820B2 (ja) | 2013-03-14 | 2020-03-25 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | マイクロ流体デバイスの段階的ロードのための毛細管バリア |
| US10117563B2 (en) * | 2014-01-09 | 2018-11-06 | Gyrus Acmi, Inc. | Polyp detection from an image |
| JP7277050B2 (ja) | 2016-01-29 | 2023-05-18 | ピューリジェン バイオシステムズ， インコーポレイテッド | 核酸の精製のための等速電気泳動 |
| WO2017151098A1 (en) * | 2016-02-29 | 2017-09-08 | Hewlett-Packard Development Company, L.P. | Liquid directing sample container |
| AU2017408261A1 (en) * | 2017-04-05 | 2019-11-28 | Dianax S.R.L. | Lab-on-a-chip diagnosis device |
| AU2018312570B2 (en) * | 2017-08-02 | 2024-01-11 | Purigen Biosystems, Inc. | Systems, devices, and methods for isotachophoresis |
| US12241907B2 (en) | 2019-04-22 | 2025-03-04 | Sekisui Chemical Co., Ltd. | Chip and fluid-merging method |
| JP7164505B2 (ja) * | 2019-10-02 | 2022-11-01 | 積水化学工業株式会社 | マイクロ流路チップ |
| US20230294094A1 (en) * | 2020-07-29 | 2023-09-21 | Kyocera Corporation | Flow channel device |
Family Cites Families (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4426451A (en) | 1981-01-28 | 1984-01-17 | Eastman Kodak Company | Multi-zoned reaction vessel having pressure-actuatable control means between zones |
| EP0373192B1 (en) | 1988-03-09 | 1996-06-12 | The Board Of Trustees Of The Leland Stanford Junior University | Diagnostic genes for toxoplasmosis |
| AU4248593A (en) | 1992-05-14 | 1993-12-13 | Mark Holodniy | Polymerase chain reaction assays for monitoring antiviral therapy |
| GB9324310D0 (en) * | 1993-11-26 | 1994-01-12 | Univ Birmingham | Liquid transfer device |
| US5827415A (en) | 1994-09-26 | 1998-10-27 | The Board Of Trustees Of Leland Stanford Jun. Univ. | Oxygen sensor |
| US6130098A (en) * | 1995-09-15 | 2000-10-10 | The Regents Of The University Of Michigan | Moving microdroplets |
| US6143248A (en) | 1996-08-12 | 2000-11-07 | Gamera Bioscience Corp. | Capillary microvalve |
| US6090251A (en) | 1997-06-06 | 2000-07-18 | Caliper Technologies, Inc. | Microfabricated structures for facilitating fluid introduction into microfluidic devices |
| US5992820A (en) | 1997-11-19 | 1999-11-30 | Sarnoff Corporation | Flow control in microfluidics devices by controlled bubble formation |
| US6601613B2 (en) | 1998-10-13 | 2003-08-05 | Biomicro Systems, Inc. | Fluid circuit components based upon passive fluid dynamics |
| KR20010089295A (ko) * | 1998-10-13 | 2001-09-29 | 마이클 알. 맥닐리 | 수동 유체 동역학에 의한 유체회로 및 유체회로내에서의방법 |
| US6626417B2 (en) | 2001-02-23 | 2003-09-30 | Becton, Dickinson And Company | Microfluidic valve and microactuator for a microvalve |
| US7429354B2 (en) | 2001-03-19 | 2008-09-30 | Gyros Patent Ab | Structural units that define fluidic functions |
| US6581438B1 (en) * | 2002-01-31 | 2003-06-24 | Sandia Corporation | Capillary test specimen, system, and methods for in-situ visualization of capillary flow and fillet formation |
| US6561224B1 (en) | 2002-02-14 | 2003-05-13 | Abbott Laboratories | Microfluidic valve and system therefor |
| TW590982B (en) | 2002-09-27 | 2004-06-11 | Agnitio Science & Technology I | Micro-fluid driving device |
| FR2848125B1 (fr) | 2002-12-04 | 2006-06-09 | Commissariat Energie Atomique | Dispositif microfluidique dans lequel l'interface liquide/fluide est stabilisee |
| DE10302721A1 (de) * | 2003-01-23 | 2004-08-05 | Steag Microparts Gmbh | Mikrofluidische Anordnung zum Dosieren von Flüssigkeiten |
| US20060002817A1 (en) * | 2004-06-30 | 2006-01-05 | Sebastian Bohm | Flow modulation devices |
| WO2006061026A2 (en) * | 2004-12-09 | 2006-06-15 | Inverness Medical Switzerland Gmbh | A micro fluidic device and methods for producing a micro fluidic device |
| US20070014695A1 (en) | 2005-04-26 | 2007-01-18 | Applera Corporation | Systems and Methods for Multiple Analyte Detection |
| EP1917097A2 (en) | 2005-07-05 | 2008-05-07 | Massachusetts Institute of Technology (MIT) | Microfluidic separators for multiphase fluid-flow based on membranes |
| US8414754B1 (en) | 2006-05-31 | 2013-04-09 | The Board Of Trustees Of The Leland Stanford Junior University | Electrophoretic sample analysis and approach therefor |
| US8562804B2 (en) | 2006-07-20 | 2013-10-22 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescent finger prints for indirect detection in isotachophoresis |
| US7951278B2 (en) | 2006-07-20 | 2011-05-31 | The Board Of Trustees Of The Leland Standford Junior University | Method of detecting directly undetectable analytes using directly detectable spacer molecules |
| JP4852399B2 (ja) * | 2006-11-22 | 2012-01-11 | 富士フイルム株式会社 | 二液合流装置 |
| US8999129B2 (en) | 2011-03-07 | 2015-04-07 | Lawrence Livermore National Security, Llc | Liquid and gel electrodes for transverse free flow electrophoresis |
| WO2008124046A1 (en) | 2007-04-04 | 2008-10-16 | Micropoint Bioscience Inc.. | Micromachined electrowetting microfluidic valve |
| US8852952B2 (en) * | 2008-05-03 | 2014-10-07 | Advanced Liquid Logic, Inc. | Method of loading a droplet actuator |
| US8394251B2 (en) | 2008-10-07 | 2013-03-12 | The Board Of Trustees Of The Leland Stanford Junior University | Control of chemical reactions using isotachophoresis |
| EP2213364A1 (en) * | 2009-01-30 | 2010-08-04 | Albert-Ludwigs-Universität Freiburg | Phase guide patterns for liquid manipulation |
| US8846314B2 (en) | 2009-03-03 | 2014-09-30 | The Board Of Trustees Of The Leland Stanford Junior University | Isotachophoretic focusing of nucleic acids |
| US9285340B2 (en) | 2009-08-17 | 2016-03-15 | Lawrence Livermore National Security, Llc | Methods for separating particles and/or nucleic acids using isotachophoresis |
| US9144799B2 (en) | 2009-11-24 | 2015-09-29 | Lawrence Livermore National Security, Llc | Modular microfluidic system for biological sample preparation |
| US8721858B2 (en) | 2010-03-12 | 2014-05-13 | The Board Of Trustees Of The Leland Stanford Junior University | Non-focusing tracers for indirect detection in electrophoretic displacement techniques |
| US8512538B2 (en) * | 2010-05-28 | 2013-08-20 | Integenx Inc. | Capillary electrophoresis device |
| US8986529B2 (en) | 2010-09-13 | 2015-03-24 | The Board Of Trustees Of The Leland Stanford Junior University | Isotachophoresis having interacting anionic and cationic shock waves |
| US9151732B2 (en) | 2010-10-01 | 2015-10-06 | The Board Of Trustees Of The Leland Stanford Junior University | Enhanced isotachophoresis assays using additives with spatial gradients |
| US8524061B2 (en) | 2010-11-29 | 2013-09-03 | The Board Of Trustees Of The Leland Stanford Junior University | On-chip hybridization coupled with ITP based purification for fast sequence specific identification |
| GB201103917D0 (en) * | 2011-03-08 | 2011-04-20 | Univ Leiden | Apparatus for and methods of processing liquids or liquid based substances |
| US9057673B2 (en) | 2012-08-24 | 2015-06-16 | The Board Of Trustees Of The Leland Stanford Junior University | Method of preparing RNA from ribonuclease-rich sources |
| JP6673820B2 (ja) | 2013-03-14 | 2020-03-25 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | マイクロ流体デバイスの段階的ロードのための毛細管バリア |
| US11325123B2 (en) | 2013-08-02 | 2022-05-10 | The Board Of Trustees Of The Leland Stanford Junior University | Flow regulation in fluidic systems using a phase-change material at system ports |
| JP7277050B2 (ja) | 2016-01-29 | 2023-05-18 | ピューリジェン バイオシステムズ， インコーポレイテッド | 核酸の精製のための等速電気泳動 |
-
2014
- 2014-03-14 JP JP2016502964A patent/JP6673820B2/ja active Active
- 2014-03-14 US US14/213,832 patent/US20160160208A1/en not_active Abandoned
- 2014-03-14 WO PCT/US2014/029017 patent/WO2014153092A1/en not_active Ceased
- 2014-03-14 GB GB1517364.4A patent/GB2526999B/en active Active
- 2014-03-14 AU AU2014236262A patent/AU2014236262A1/en not_active Abandoned
- 2014-03-14 EP EP14769958.1A patent/EP2972185A4/en active Pending
- 2014-03-14 CN CN201910521030.XA patent/CN110243637B/zh active Active
- 2014-03-14 CN CN201480021876.2A patent/CN105190280B/zh active Active
- 2014-03-14 CA CA2906730A patent/CA2906730C/en active Active
-
2017
- 2017-12-22 US US15/853,370 patent/US10233441B2/en active Active
-
2018
- 2018-07-17 AU AU2018206716A patent/AU2018206716A1/en not_active Abandoned
- 2018-11-15 US US16/192,034 patent/US10787660B2/en active Active
-
2020
- 2020-03-05 JP JP2020037919A patent/JP2020109413A/ja active Pending
- 2020-08-20 US US16/998,839 patent/US11851647B2/en active Active
- 2020-09-25 AU AU2020239798A patent/AU2020239798B2/en active Active
-
2023
- 2023-04-04 AU AU2023202077A patent/AU2023202077B2/en active Active
- 2023-11-08 US US18/388,047 patent/US12435329B2/en active Active
-
2025
- 2025-07-09 US US19/263,805 patent/US20250333722A1/en active Pending
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