JP2016511747A5 - - Google Patents
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- Publication number
- JP2016511747A5 JP2016511747A5 JP2015551772A JP2015551772A JP2016511747A5 JP 2016511747 A5 JP2016511747 A5 JP 2016511747A5 JP 2015551772 A JP2015551772 A JP 2015551772A JP 2015551772 A JP2015551772 A JP 2015551772A JP 2016511747 A5 JP2016511747 A5 JP 2016511747A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- peptide
- connective tissue
- polymer
- active agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002105 nanoparticle Substances 0.000 claims 12
- 108090000765 processed proteins & peptides Proteins 0.000 claims 12
- 239000013543 active substance Substances 0.000 claims 8
- 210000002808 connective tissue Anatomy 0.000 claims 8
- 239000011859 microparticle Substances 0.000 claims 8
- 229920000642 polymer Polymers 0.000 claims 8
- 239000002245 particle Substances 0.000 claims 7
- 239000003814 drug Substances 0.000 claims 5
- 229940124597 therapeutic agent Drugs 0.000 claims 5
- 125000003275 alpha amino acid group Chemical group 0.000 claims 4
- 150000001413 amino acids Chemical class 0.000 claims 4
- 108090001008 Avidin Proteins 0.000 claims 3
- 208000023178 Musculoskeletal disease Diseases 0.000 claims 2
- 206010073713 Musculoskeletal injury Diseases 0.000 claims 2
- 230000006378 damage Effects 0.000 claims 2
- 201000010099 disease Diseases 0.000 claims 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
- 239000012634 fragment Substances 0.000 claims 2
- 102000004196 processed proteins & peptides Human genes 0.000 claims 2
- 208000020084 Bone disease Diseases 0.000 claims 1
- 230000003160 anti-catabolic effect Effects 0.000 claims 1
- 229940124346 antiarthritic agent Drugs 0.000 claims 1
- 239000003435 antirheumatic agent Substances 0.000 claims 1
- 210000000988 bone and bone Anatomy 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 208000018631 connective tissue disease Diseases 0.000 claims 1
- 239000003102 growth factor Substances 0.000 claims 1
- 208000017445 musculoskeletal system disease Diseases 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361748809P | 2013-01-04 | 2013-01-04 | |
| US61/748,809 | 2013-01-04 | ||
| US201361870288P | 2013-08-27 | 2013-08-27 | |
| US61/870,288 | 2013-08-27 | ||
| PCT/US2014/010162 WO2014107566A1 (en) | 2013-01-04 | 2014-01-03 | Surface binding of nanoparticle based drug delivery to tissue |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2016511747A JP2016511747A (ja) | 2016-04-21 |
| JP2016511747A5 true JP2016511747A5 (enExample) | 2017-06-29 |
Family
ID=51061134
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015551772A Pending JP2016511747A (ja) | 2013-01-04 | 2014-01-03 | ナノ粒子表面結合に基づく薬物の組織への送達 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US9289506B2 (enExample) |
| EP (1) | EP2941243A4 (enExample) |
| JP (1) | JP2016511747A (enExample) |
| WO (1) | WO2014107566A1 (enExample) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2013540757A (ja) | 2010-09-24 | 2013-11-07 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッド | カプセル化された作用物質の放出を制御する能力を有するナノ構造ゲル |
| GB201412610D0 (en) * | 2014-07-16 | 2014-08-27 | Univ Cardiff | Cartilage agent delivery |
| US20190002530A1 (en) * | 2015-12-25 | 2019-01-03 | Konica Minolta, Inc. | Gelatin particles, method for producing gelatin particles, gelatin particle-containing cell, and method for producing gelatin particle-containing cell |
| US10188749B2 (en) | 2016-04-14 | 2019-01-29 | Fred Hutchinson Cancer Research Center | Compositions and methods to program therapeutic cells using targeted nucleic acid nanocarriers |
| US10583199B2 (en) * | 2016-04-26 | 2020-03-10 | Northwestern University | Nanocarriers having surface conjugated peptides and uses thereof for sustained local release of drugs |
| EP3978022A1 (en) * | 2016-05-06 | 2022-04-06 | The Brigham and Women's Hospital, Inc. | Binary self assembled gels for controlled delivery of encapsulated agents to cartilage |
| CA3049244A1 (en) * | 2017-01-05 | 2018-07-12 | Fred Hutchinson Cancer Research Center | Systems and methods to improve vaccine efficacy |
| CN108531616B (zh) * | 2018-04-28 | 2021-08-10 | 中国农业科学院兰州畜牧与兽药研究所 | 一种牦牛体格相关的基因分子标记、检测方法和试剂盒 |
| US11839605B2 (en) | 2018-10-11 | 2023-12-12 | Alivio Therapeutics, Inc. | Non-injectable hydrogel formulations for smart release |
| US20210023236A1 (en) * | 2019-07-26 | 2021-01-28 | Massachusetts Institute Of Technology | Multi-targeted, tunable, sustained delivery of payloads to charged avascular tissues |
| US20210154307A1 (en) * | 2019-11-07 | 2021-05-27 | Northeastern University | Cationic nanostructures for intra-cartilage delivery of therapeutics and contrast agents |
Family Cites Families (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU630497B2 (en) * | 1989-09-05 | 1992-10-29 | Immunex Corporation | Tumor necrosis factor-alpha and -beta receptors |
| US8795242B2 (en) | 1994-05-13 | 2014-08-05 | Kensey Nash Corporation | Resorbable polymeric device for localized drug delivery |
| US5723125A (en) | 1995-12-28 | 1998-03-03 | Tanox Biosystems, Inc. | Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide |
| US6958148B1 (en) | 1998-01-20 | 2005-10-25 | Pericor Science, Inc. | Linkage of agents to body tissue using microparticles and transglutaminase |
| US20060084794A1 (en) * | 2001-04-12 | 2006-04-20 | Human Genome Sciences, Inc. | Albumin fusion proteins |
| ITRM20020128A1 (it) | 2002-03-08 | 2003-09-08 | Sigma Tau Ind Farmaceuti | Dimeri di avidina efficaci nell'incrementare la concentrazione di biotina radioattiva nella immunoterapia con "pretargeting". |
| PL377091A1 (pl) * | 2002-09-06 | 2006-01-23 | Amgen, Inc. | Ludzkie monoklonalne przeciwciało przeciw-IL-1R1, o właściwościach terapeutycznych |
| GB0313569D0 (en) | 2003-06-12 | 2003-07-16 | Plasso Technology Ltd | Method |
| WO2005072893A1 (en) * | 2004-01-28 | 2005-08-11 | Cytimmune Sciences, Inc. | Functionalized colloidal metal compositions and methods |
| US8128908B2 (en) | 2004-04-30 | 2012-03-06 | University Of Florida Research Foundation, Inc. | Nanoparticles and their use for multifunctional bioimaging |
| US20090324678A1 (en) | 2004-07-16 | 2009-12-31 | Spinal Restoration, Inc. | Methods and kits for treating joints and soft tissues |
| JP2006247155A (ja) | 2005-03-11 | 2006-09-21 | Aruze Corp | タイピングゲーム装置及びデータベースシステム |
| MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
| US20100015068A1 (en) | 2006-07-06 | 2010-01-21 | Massachusetts Institute Of Technology | Methods and Compositions For Altering Biological Surfaces |
| US7592009B2 (en) * | 2006-10-10 | 2009-09-22 | Ecole Polytechnique Federale De Lausanne (Epfl) | Polypeptide ligands for targeting cartilage and methods of use thereof |
| TW201531484A (zh) * | 2007-05-21 | 2015-08-16 | Alder Biopharmaceuticals Inc | 抗ＴＮＦ-α之抗體及其用途 |
| KR101544628B1 (ko) | 2007-08-02 | 2015-08-17 | 시구마-토우인더스트리에파아마슈우티히리유니트에스.피이.에이. | 처리 조직에서의 체류 시간이 긴 산화 아비딘 |
| US20110104052A1 (en) | 2007-12-03 | 2011-05-05 | The Johns Hopkins University | Methods of synthesis and use of chemospheres |
| JP2009292787A (ja) * | 2008-06-06 | 2009-12-17 | Ab Size:Kk | 軟骨再生促進剤 |
| US9333163B2 (en) | 2008-10-06 | 2016-05-10 | Massachusetts Institute Of Technology | Particles with multiple functionalized surface domains |
| US9198873B2 (en) * | 2010-07-19 | 2015-12-01 | National Cheng Kung University | Functionalized nanoparticle, method for preparing the same and application thereof |
| ES2729549T3 (es) | 2011-08-02 | 2019-11-04 | Alfasigma Spa | Composición farmacéutica de avidina oxidada adecuada para la inhalación |
-
2014
- 2014-01-03 EP EP14735208.2A patent/EP2941243A4/en not_active Withdrawn
- 2014-01-03 JP JP2015551772A patent/JP2016511747A/ja active Pending
- 2014-01-03 WO PCT/US2014/010162 patent/WO2014107566A1/en not_active Ceased
- 2014-01-06 US US14/147,863 patent/US9289506B2/en active Active
-
2016
- 2016-03-16 US US15/071,709 patent/US10226427B2/en active Active