JP2016509865A5 - - Google Patents
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- Publication number
- JP2016509865A5 JP2016509865A5 JP2015562512A JP2015562512A JP2016509865A5 JP 2016509865 A5 JP2016509865 A5 JP 2016509865A5 JP 2015562512 A JP2015562512 A JP 2015562512A JP 2015562512 A JP2015562512 A JP 2015562512A JP 2016509865 A5 JP2016509865 A5 JP 2016509865A5
- Authority
- JP
- Japan
- Prior art keywords
- plant
- fad2
- soybean
- alleles
- mutation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000196324 Embryophyta Species 0.000 claims 40
- 244000068988 Glycine max Species 0.000 claims 27
- 108700028369 Alleles Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 19
- 230000035772 mutation Effects 0.000 claims 19
- 102000004533 Endonucleases Human genes 0.000 claims 10
- 108010042407 Endonucleases Proteins 0.000 claims 10
- 108700019146 Transgenes Proteins 0.000 claims 5
- 108010073062 Transcription Activator-Like Effectors Proteins 0.000 claims 3
- 230000037430 deletion Effects 0.000 claims 3
- 238000012217 deletion Methods 0.000 claims 3
- 239000003921 oil Substances 0.000 claims 3
- 235000019198 oils Nutrition 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims 2
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims 2
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims 2
- 239000005642 Oleic acid Substances 0.000 claims 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 claims 2
- 235000020778 linoleic acid Nutrition 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 235000010469 Glycine max Nutrition 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 235000012424 soybean oil Nutrition 0.000 claims 1
- 239000003549 soybean oil Substances 0.000 claims 1
- 230000002103 transcriptional effect Effects 0.000 claims 1
- 108700026220 vif Genes Proteins 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790655P | 2013-03-15 | 2013-03-15 | |
| US61/790,655 | 2013-03-15 | ||
| US201361885213P | 2013-10-01 | 2013-10-01 | |
| US61/885,213 | 2013-10-01 | ||
| PCT/IB2014/059752 WO2014141147A1 (en) | 2013-03-15 | 2014-03-13 | Modifying soybean oil composition through targeted knockout of the fad2-1a/1b genes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016509865A JP2016509865A (ja) | 2016-04-04 |
| JP2016509865A5 true JP2016509865A5 (enExample) | 2017-04-13 |
| JP6591898B2 JP6591898B2 (ja) | 2019-10-16 |
Family
ID=50543262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562512A Active JP6591898B2 (ja) | 2013-03-15 | 2014-03-13 | Ｆａｄ２−１ａ／１ｂ遺伝子の標的化ノックアウトを介した、大豆油組成物の改変 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2966983B1 (enExample) |
| JP (1) | JP6591898B2 (enExample) |
| CN (1) | CN105246324B (enExample) |
| BR (1) | BR112015022778B1 (enExample) |
| CA (1) | CA2906406C (enExample) |
| WO (1) | WO2014141147A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA118090C2 (uk) | 2012-09-07 | 2018-11-26 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив |
| ES3039237T3 (en) | 2016-02-02 | 2025-10-20 | Cellectis | Modifying soybean oil composition through targeted knockout of the fad3a/b/c genes |
| EA202091316A1 (ru) | 2016-12-22 | 2020-08-18 | Тулджин Инкорпорейтид | Обогащенный олеиновой кислотой растительный организм, имеющий генетически модифицированный fad2, и способ его получения |
| CN108374007B (zh) * | 2018-02-03 | 2021-09-21 | 吉林省农业科学院 | 高油酸转基因大豆事件eb8072外源插入片段侧翼序列及其应用 |
| AU2020350760B2 (en) * | 2019-09-20 | 2024-10-31 | Cibus Europe B.V. | Low phytoestrogen soybean based on gene editing |
| WO2021108248A1 (en) * | 2019-11-27 | 2021-06-03 | Calyxt, Inc. | Tal-effector nucleases for gene editing |
| CN112680465A (zh) * | 2020-12-28 | 2021-04-20 | 浙江农林大学 | 用于改造大豆脂肪酸组分的基因突变体及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6414223B1 (en) * | 1998-08-03 | 2002-07-02 | Cargill, Incorporated | Plants, seeds and oils having an elevated total monounsaturated fatty acid content |
| US6453242B1 (en) * | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US20060206949A1 (en) * | 2003-01-28 | 2006-09-14 | Sylvain Arnould | Custom-made meganuclease and use thereof |
| CN100339481C (zh) * | 2005-03-17 | 2007-09-26 | 东北师范大学 | 应用基因沉默技术提高大豆和花生的种子油酸含量的方法 |
| CA2765560C (en) * | 2009-06-22 | 2017-10-31 | Saga University | Mutation that increases the oleic acid content in soybean oil and responsible gene thereof |
| CN105557503A (zh) * | 2009-07-08 | 2016-05-11 | 密苏里大学管委会 | 利用传统大豆育种技术培育高油酸大豆的方法 |
| CN102782140B (zh) * | 2009-10-22 | 2016-04-13 | 陶氏农业科学有限公司 | 靶向参与脂肪酸生物合成的植物基因的工程改造锌指蛋白 |
| PT2816112T (pt) * | 2009-12-10 | 2018-11-20 | Univ Iowa State Res Found Inc | Modificação do adn modificada pelo efector tal |
| PY1202285A (es) * | 2011-01-14 | 2015-11-02 | Univ Missouri | Método para desarrollar granos de soja con alto contenido de ácido oleico usando técnicas convencionales de reproducción de la soja |
| UA118090C2 (uk) * | 2012-09-07 | 2018-11-26 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив |
-
2014
- 2014-03-13 BR BR112015022778-3A patent/BR112015022778B1/pt active IP Right Grant
- 2014-03-13 CA CA2906406A patent/CA2906406C/en active Active
- 2014-03-13 EP EP14718749.6A patent/EP2966983B1/en active Active
- 2014-03-13 JP JP2015562512A patent/JP6591898B2/ja active Active
- 2014-03-13 CN CN201480028282.4A patent/CN105246324B/zh active Active
- 2014-03-13 WO PCT/IB2014/059752 patent/WO2014141147A1/en not_active Ceased
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