JP2016509865A5 - - Google Patents
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- Publication number
- JP2016509865A5 JP2016509865A5 JP2015562512A JP2015562512A JP2016509865A5 JP 2016509865 A5 JP2016509865 A5 JP 2016509865A5 JP 2015562512 A JP2015562512 A JP 2015562512A JP 2015562512 A JP2015562512 A JP 2015562512A JP 2016509865 A5 JP2016509865 A5 JP 2016509865A5
- Authority
- JP
- Japan
- Prior art keywords
- plant
- fad2
- soybean
- alleles
- mutation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000196324 Embryophyta Species 0.000 claims 40
- 244000068988 Glycine max Species 0.000 claims 27
- 108700028369 Alleles Proteins 0.000 claims 22
- 238000000034 method Methods 0.000 claims 19
- 230000035772 mutation Effects 0.000 claims 19
- 102000004533 Endonucleases Human genes 0.000 claims 10
- 108010042407 Endonucleases Proteins 0.000 claims 10
- 108700019146 Transgenes Proteins 0.000 claims 5
- 108010073062 Transcription Activator-Like Effectors Proteins 0.000 claims 3
- 230000037430 deletion Effects 0.000 claims 3
- 238000012217 deletion Methods 0.000 claims 3
- 239000003921 oil Substances 0.000 claims 3
- 235000019198 oils Nutrition 0.000 claims 3
- 108090000623 proteins and genes Proteins 0.000 claims 3
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims 2
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims 2
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims 2
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 claims 2
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims 2
- 239000005642 Oleic acid Substances 0.000 claims 2
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims 2
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 claims 2
- 235000020778 linoleic acid Nutrition 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims 2
- 108020004414 DNA Proteins 0.000 claims 1
- 235000010469 Glycine max Nutrition 0.000 claims 1
- 230000003247 decreasing effect Effects 0.000 claims 1
- 239000012636 effector Substances 0.000 claims 1
- 230000001172 regenerating effect Effects 0.000 claims 1
- 238000012216 screening Methods 0.000 claims 1
- 235000012424 soybean oil Nutrition 0.000 claims 1
- 239000003549 soybean oil Substances 0.000 claims 1
- 230000002103 transcriptional effect Effects 0.000 claims 1
- 108700026220 vif Genes Proteins 0.000 claims 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361790655P | 2013-03-15 | 2013-03-15 | |
| US61/790,655 | 2013-03-15 | ||
| US201361885213P | 2013-10-01 | 2013-10-01 | |
| US61/885,213 | 2013-10-01 | ||
| PCT/IB2014/059752 WO2014141147A1 (en) | 2013-03-15 | 2014-03-13 | Modifying soybean oil composition through targeted knockout of the fad2-1a/1b genes |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016509865A JP2016509865A (ja) | 2016-04-04 |
| JP2016509865A5 true JP2016509865A5 (enExample) | 2017-04-13 |
| JP6591898B2 JP6591898B2 (ja) | 2019-10-16 |
Family
ID=50543262
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015562512A Active JP6591898B2 (ja) | 2013-03-15 | 2014-03-13 | Ｆａｄ２−１ａ／１ｂ遺伝子の標的化ノックアウトを介した、大豆油組成物の改変 |
Country Status (6)
| Country | Link |
|---|---|
| EP (1) | EP2966983B1 (enExample) |
| JP (1) | JP6591898B2 (enExample) |
| CN (1) | CN105246324B (enExample) |
| BR (1) | BR112015022778B1 (enExample) |
| CA (1) | CA2906406C (enExample) |
| WO (1) | WO2014141147A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| UA118090C2 (uk) * | 2012-09-07 | 2018-11-26 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив |
| EP4646936A3 (en) * | 2016-02-02 | 2025-11-19 | Cellectis | Modifying soybean oil composition through targeted knockout of the fad3a/b/c genes |
| AU2017379402B2 (en) * | 2016-12-22 | 2022-03-10 | Toolgen Incorporated | Oleic acid-enriched plant body having genetically modified FAD2 and production method therefor |
| CN108374007B (zh) * | 2018-02-03 | 2021-09-21 | 吉林省农业科学院 | 高油酸转基因大豆事件eb8072外源插入片段侧翼序列及其应用 |
| CA3150522A1 (en) * | 2019-09-20 | 2021-03-25 | Jim PRESNAIL | LOW PHYTOESTROGEN SOY BASED ON GENOMIC EDITING |
| CN114787364A (zh) * | 2019-11-27 | 2022-07-22 | 卡里克特公司 | 用于基因编辑的tal效应物核酸酶 |
| CN112680465A (zh) * | 2020-12-28 | 2021-04-20 | 浙江农林大学 | 用于改造大豆脂肪酸组分的基因突变体及其应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6414223B1 (en) * | 1998-08-03 | 2002-07-02 | Cargill, Incorporated | Plants, seeds and oils having an elevated total monounsaturated fatty acid content |
| US6453242B1 (en) * | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| AU2004208031B2 (en) * | 2003-01-28 | 2009-10-08 | Cellectis | Use of meganucleases for inducing homologous recombination ex vivo and in toto in vertebrate somatic tissues and application thereof. |
| CN100339481C (zh) * | 2005-03-17 | 2007-09-26 | 东北师范大学 | 应用基因沉默技术提高大豆和花生的种子油酸含量的方法 |
| JP5665004B2 (ja) * | 2009-06-22 | 2015-02-04 | 国立大学法人佐賀大学 | ダイズ油脂中のオレイン酸含量を増加させる突然変異体及びその原因遺伝子 |
| CN105557503A (zh) * | 2009-07-08 | 2016-05-11 | 密苏里大学管委会 | 利用传统大豆育种技术培育高油酸大豆的方法 |
| KR101813981B1 (ko) * | 2009-10-22 | 2018-01-04 | 다우 아그로사이언시즈 엘엘씨 | 지방산 생합성에 포함된 식물 유전자를 표적하는 조작된 징크 핑거 단백질 |
| NO2510096T3 (enExample) | 2009-12-10 | 2015-03-21 | ||
| AR085892A1 (es) * | 2011-01-14 | 2013-11-06 | Univ Missouri | Metodo para desarrollar soja con un contenido elevado de acido oleico usando tecnicas de desarrollo convencionales |
| UA118090C2 (uk) * | 2012-09-07 | 2018-11-26 | ДАУ АГРОСАЙЄНСІЗ ЕлЕлСі | Спосіб інтегрування послідовності нуклеїнової кислоти, що представляє інтерес, у ген fad2 у клітині сої та специфічний для локусу fad2 білок, що зв'язується, здатний індукувати спрямований розрив |
-
2014
- 2014-03-13 WO PCT/IB2014/059752 patent/WO2014141147A1/en not_active Ceased
- 2014-03-13 JP JP2015562512A patent/JP6591898B2/ja active Active
- 2014-03-13 CA CA2906406A patent/CA2906406C/en active Active
- 2014-03-13 EP EP14718749.6A patent/EP2966983B1/en active Active
- 2014-03-13 CN CN201480028282.4A patent/CN105246324B/zh active Active
- 2014-03-13 BR BR112015022778-3A patent/BR112015022778B1/pt active IP Right Grant
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