JP2016508789A - 膣内避妊具および該膣内避妊具における有効成分の拡散速度を減少させる方法 - Google Patents

膣内避妊具および該膣内避妊具における有効成分の拡散速度を減少させる方法 Download PDF

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JP2016508789A
JP2016508789A JP2015556594A JP2015556594A JP2016508789A JP 2016508789 A JP2016508789 A JP 2016508789A JP 2015556594 A JP2015556594 A JP 2015556594A JP 2015556594 A JP2015556594 A JP 2015556594A JP 2016508789 A JP2016508789 A JP 2016508789A
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Prior art keywords
layer
intrauterine
particulate material
active ingredient
contraceptive device
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Pending
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Japanese (ja)
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JP2016508789A5 (enExample
Inventor
ヨン イングヴァル フェルトブラード ケンドループ，
ヨン イングヴァル フェルトブラード ケンドループ，
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クーファルマ アクチエボラグ
クーファルマ アクチエボラグ
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Publication of JP2016508789A5 publication Critical patent/JP2016508789A5/ja
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/08—Pessaries, i.e. devices worn in the vagina to support the uterus, remedy a malposition or prevent conception, e.g. combined with devices protecting against contagion
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F6/00—Contraceptive devices; Pessaries; Applicators therefor
    • A61F6/06—Contraceptive devices; Pessaries; Applicators therefor for use by females
    • A61F6/14—Contraceptive devices; Pessaries; Applicators therefor for use by females intra-uterine type
    • A61F6/142—Wirelike structures, e.g. loops, rings, spirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/567—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in position 17 alpha, e.g. mestranol, norethandrolone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A61K31/585—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin containing lactone rings, e.g. oxandrolone, bufalin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
    • A61K9/0039—Devices retained in the uterus for a prolonged period, e.g. intrauterine devices for contraception
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Reproductive Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Gynecology & Obstetrics (AREA)
  • Inorganic Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
JP2015556594A 2013-02-08 2014-01-31 膣内避妊具および該膣内避妊具における有効成分の拡散速度を減少させる方法 Pending JP2016508789A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1350155-6 2013-02-08
SE1350155 2013-02-08
PCT/IB2014/058696 WO2014122563A1 (en) 2013-02-08 2014-01-31 An intra vaginal device, and a method of reducing the rate of diffusion of active ingredients in said intra vaginal device

Publications (2)

Publication Number Publication Date
JP2016508789A true JP2016508789A (ja) 2016-03-24
JP2016508789A5 JP2016508789A5 (enExample) 2017-03-09

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JP2015556594A Pending JP2016508789A (ja) 2013-02-08 2014-01-31 膣内避妊具および該膣内避妊具における有効成分の拡散速度を減少させる方法

Country Status (6)

Country Link
US (2) US9775905B2 (enExample)
EP (1) EP2953595B1 (enExample)
JP (1) JP2016508789A (enExample)
ES (1) ES2787882T3 (enExample)
HU (1) HUE049219T2 (enExample)
WO (1) WO2014122563A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025503105A (ja) * 2022-01-21 2025-01-30 セバー ファーマ ソリューションズ 膣内リング
JP2025506074A (ja) * 2022-01-21 2025-03-06 セバー ファーマ ソリューションズ 薬物送達システム

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE539540C2 (sv) 2013-09-12 2017-10-10 Qpharma Ab Ett läkemedelsavgivningssystem för en eller flera aktiva beståndsdelar
CN108135910B (zh) * 2015-05-13 2022-12-02 拜耳股份有限公司 长效药物递送装置及其在避孕中的用途
CN108392310A (zh) * 2018-02-28 2018-08-14 张晓光 免更换宫内节育器
USD935018S1 (en) * 2020-04-07 2021-11-02 The Population Council, Inc. Contraceptive

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292965A (en) * 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
US20030092817A1 (en) * 2001-11-06 2003-05-15 Rodney Ruskin Method to reduce the rate of diffusion of slow-release materials through polymers and process for making drip irrigation devices with long-term control of root growth
US20040213846A1 (en) * 2003-04-23 2004-10-28 Greenblatt Gary David Polymer-clay nanocomposite for extended release of active ingredient
WO2013013172A1 (en) * 2011-07-20 2013-01-24 The University Of Utah Research Foundation Intravaginal devices for drug delivery

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3845761A (en) * 1970-06-02 1974-11-05 Alza Corp Intrauterine contraceptive anti-fertility device for the management of reproduction
US3903880A (en) * 1972-08-17 1975-09-09 Alza Corp Intrauterine device for managing the reproductive process
US4069307A (en) 1970-10-01 1978-01-17 Alza Corporation Drug-delivery device comprising certain polymeric materials for controlled release of drug
EG11114A (en) 1973-12-06 1977-01-31 Schering Ag Dispositif contraceptif intra-uterin
US4728478A (en) * 1982-08-05 1988-03-01 Allied-Signal Inc. Polymer films containing platelet particles
US4601714A (en) 1983-07-07 1986-07-22 Burnhill Michael S Vaginal device
US5972372A (en) 1996-07-31 1999-10-26 The Population Council, Inc. Intravaginal rings with insertable drug-containing core
US20060251824A1 (en) * 2005-05-05 2006-11-09 Boulais Dennis R Coating of medical devices with solids
WO2009003125A1 (en) * 2007-06-26 2008-12-31 Warner Chilcott Company,Inc. Intravaginal drug delivery devices for the delivery of macromolecules and water-soluble drugs
CA2713943C (en) 2008-02-04 2018-10-23 Teva Women's Health, Inc. Monolithic intravaginal rings comprising progesterone and methods of making and uses thereof
EP2790637A4 (en) * 2011-12-16 2015-04-29 Combinent Biomedical Systems Inc VAGINAL DRUG DELIVERY DEVICES AND METHODS OF MANUFACTURING THE SAME

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4292965A (en) * 1978-12-29 1981-10-06 The Population Council, Inc. Intravaginal ring
US20030092817A1 (en) * 2001-11-06 2003-05-15 Rodney Ruskin Method to reduce the rate of diffusion of slow-release materials through polymers and process for making drip irrigation devices with long-term control of root growth
US20040213846A1 (en) * 2003-04-23 2004-10-28 Greenblatt Gary David Polymer-clay nanocomposite for extended release of active ingredient
WO2013013172A1 (en) * 2011-07-20 2013-01-24 The University Of Utah Research Foundation Intravaginal devices for drug delivery

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2025503105A (ja) * 2022-01-21 2025-01-30 セバー ファーマ ソリューションズ 膣内リング
JP2025506074A (ja) * 2022-01-21 2025-03-06 セバー ファーマ ソリューションズ 薬物送達システム
JP7692537B2 (ja) 2022-01-21 2025-06-13 セバー ファーマ ソリューションズ 膣内リング

Also Published As

Publication number Publication date
EP2953595A1 (en) 2015-12-16
EP2953595B1 (en) 2020-03-11
US11872284B2 (en) 2024-01-16
US9775905B2 (en) 2017-10-03
ES2787882T3 (es) 2020-10-19
HUE049219T2 (hu) 2020-09-28
US20170252444A1 (en) 2017-09-07
WO2014122563A1 (en) 2014-08-14
US20150359890A1 (en) 2015-12-17

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