JP2016501236A - 炎症性皮膚状態の予防および治療のための方法 - Google Patents

炎症性皮膚状態の予防および治療のための方法 Download PDF

Info

Publication number
JP2016501236A
JP2016501236A JP2015545609A JP2015545609A JP2016501236A JP 2016501236 A JP2016501236 A JP 2016501236A JP 2015545609 A JP2015545609 A JP 2015545609A JP 2015545609 A JP2015545609 A JP 2015545609A JP 2016501236 A JP2016501236 A JP 2016501236A
Authority
JP
Japan
Prior art keywords
condition
aha
aqa
ata
therapeutic agent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2015545609A
Other languages
English (en)
Japanese (ja)
Other versions
JP2016501236A5 (enExample
Inventor
パトリック エル． マクギアー、
パトリック エル． マクギアー、
ムンヒ イ、
ムンヒ イ、
ダグラス エヌ． ベル、
ダグラス エヌ． ベル、
Original Assignee
アウリン バイオテック インコーポレイテッド
アウリン バイオテック インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by アウリン バイオテック インコーポレイテッド, アウリン バイオテック インコーポレイテッド filed Critical アウリン バイオテック インコーポレイテッド
Publication of JP2016501236A publication Critical patent/JP2016501236A/ja
Publication of JP2016501236A5 publication Critical patent/JP2016501236A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/194—Carboxylic acids, e.g. valproic acid having two or more carboxyl groups, e.g. succinic, maleic or phthalic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/08—Antiseborrheics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/28—Antiandrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Botany (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Birds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Emergency Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015545609A 2012-12-06 2013-06-21 炎症性皮膚状態の予防および治療のための方法 Pending JP2016501236A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13/694,484 US8877808B2 (en) 2012-12-06 2012-12-06 Protection against skin diseases by aurin tricarboxylic acid and its derivatives
US13/694,484 2012-12-06
PCT/CA2013/050488 WO2014085920A1 (en) 2012-12-06 2013-06-21 Methods for preventing and treating inflammatory skin conditions

Publications (2)

Publication Number Publication Date
JP2016501236A true JP2016501236A (ja) 2016-01-18
JP2016501236A5 JP2016501236A5 (enExample) 2016-05-26

Family

ID=50881631

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015545609A Pending JP2016501236A (ja) 2012-12-06 2013-06-21 炎症性皮膚状態の予防および治療のための方法

Country Status (7)

Country Link
US (1) US8877808B2 (enExample)
EP (1) EP2928460B1 (enExample)
JP (1) JP2016501236A (enExample)
KR (1) KR20150090920A (enExample)
CN (1) CN104902886A (enExample)
CA (1) CA2893966C (enExample)
WO (1) WO2014085920A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10588879B2 (en) 2011-08-01 2020-03-17 Aurin Biotech Inc. Treatment of age-related macular degeneration
EP3071543B1 (en) 2013-11-18 2019-10-02 Aurin Biotech Inc. Acetyl salicyclic acid dimers, synthesis thereof, and uses thereof to prevent and treat complement-mediated disorders
US11013750B2 (en) 2017-01-20 2021-05-25 Aurin Biotech Inc. Methods for treating and preventing nociceptive pain

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4007270A (en) * 1975-11-18 1977-02-08 American Cyanamid Company Complement inhibitors
US6538028B1 (en) * 2000-02-01 2003-03-25 Vanderbilt University Method for inhibiting complement activation
JP2003525243A (ja) * 2000-02-28 2003-08-26 ザ ユニバーシティ オブ ブリティッシュ コロンビア 炎症性疾患の治療のための組成物及び方法
JP2015522060A (ja) * 2012-07-13 2015-08-03 アウリン バイオテック インコーポレイテッド アウリントリカルボン酸合成複合体の低分子量成分による、補体の膜侵襲複合体およびｃ３転換酵素の選択的阻害

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5030442A (en) 1987-03-30 1991-07-09 Liposome Technology, Inc. Non-crystalline minoxidil composition
DE4222534A1 (de) * 1992-07-09 1994-01-13 Behringwerke Ag Verwendung von Komplement-Inhibitoren zur Herstellung eines Arzneimittels zur Prophylaxe und Therapie von entzündlichen Darm- und Hauterkrankungen sowie Purpura
US5434185A (en) 1993-05-17 1995-07-18 The University Of Kentucky Research Foundation Method for inhibiting angiogenesis with aurintricarboxylic acid, its analogues or salts
US6770633B1 (en) * 1999-10-26 2004-08-03 Immusol, Inc. Ribozyme therapy for the treatment of proliferative skin and eye diseases
EP1223950B1 (en) 1999-10-26 2006-01-04 Immusol, Inc. Ribozyme therapy for the treatment of proliferative eye diseases
US20110189310A1 (en) 2008-10-08 2011-08-04 Cornell University Small molecule modulators of prongf uptake
US20130035392A1 (en) 2011-08-01 2013-02-07 Mcgeer Patrick L Selective inhibition of the membrane attack complex of complement and C3 convertase by low molecular weight components of the aurin tricarboxylic acid synthetic complex
US10966945B2 (en) 2011-08-01 2021-04-06 Aurin Biotech Inc. Selective inhibition of the membrane attack complex of complement by low molecular weight components of the aurin tricarboxylic synthetic complex

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4007270A (en) * 1975-11-18 1977-02-08 American Cyanamid Company Complement inhibitors
US6538028B1 (en) * 2000-02-01 2003-03-25 Vanderbilt University Method for inhibiting complement activation
JP2003525243A (ja) * 2000-02-28 2003-08-26 ザ ユニバーシティ オブ ブリティッシュ コロンビア 炎症性疾患の治療のための組成物及び方法
JP2015522060A (ja) * 2012-07-13 2015-08-03 アウリン バイオテック インコーポレイテッド アウリントリカルボン酸合成複合体の低分子量成分による、補体の膜侵襲複合体およびｃ３転換酵素の選択的阻害

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ACTA DERMATOVEN APA, vol. 20, no. 1, JPN6016048617, 2011, pages 3 - 11, ISSN: 0003462980 *
NEUROBIOLOGY OF AGING, vol. 33, JPN6016048616, October 2012 (2012-10-01), pages 2237 - 2246, ISSN: 0003462978 *
臨床病理, vol. 54, no. 7, JPN6016048618, 2006, pages 744 - 756, ISSN: 0003462979 *

Also Published As

Publication number Publication date
CA2893966C (en) 2018-09-18
EP2928460A1 (en) 2015-10-14
EP2928460B1 (en) 2017-12-27
CN104902886A (zh) 2015-09-09
WO2014085920A1 (en) 2014-06-12
KR20150090920A (ko) 2015-08-06
WO2014085920A9 (en) 2015-05-21
US8877808B2 (en) 2014-11-04
EP2928460A4 (en) 2016-08-17
CA2893966A1 (en) 2014-06-12
US20140163106A1 (en) 2014-06-12

Similar Documents

Publication Publication Date Title
JP5570992B2 (ja) 皮膚病又は皮膚病変の治療方法及び組成物
ES2198476T3 (es) Inhibidores de no-sintasa.
AU2016202140B2 (en) Compositions for skin exfoliation and use thereof
US12440432B2 (en) Methods and compositions for treatment of skin
KR101205209B1 (ko) 탈모방지 및 발모촉진용 외용제 조성물
JP2010502700A (ja) アクネを治療する医薬品、加齢および日焼けの症状を回復する医薬品、及び、これを用いた方法
CN105263469A (zh) 包含比马前列素的局部组合物和利用其刺激毛发生长的方法
KR20120118064A (ko) 염증후 과다색소침착의 감소로 비코카서스인 모집단에서의 여드름 치료를 위한 아다팔렌과 벤조일 퍼옥사이드의 조합물을 포함하는 피부용 조성물
PL190755B1 (pl) Preparat do leczenia i profilaktyki chorób skóry
CN110769817A (zh) 皮肤治疗方法、含类视黄醇的组合物及其递送系统
CA2893966C (en) Topical treatment of inflammatory skin conditions using a combination of aurin tricarboxylic, aurin quadracarboxylic and aurin hexacarboxylic acids
CN111936130B (zh) 包含锶和甲基磺酰基甲烷（msm）的局部制剂及治疗方法
US20200030398A1 (en) Skin care composition
EP2046273A2 (en) Rinse-off therapeutic agents for treating skin
JP2016501236A5 (enExample)
Patel et al. Clinical assessment of the combination therapy with liposomal gels of tretinoin and benzoyl peroxide in acne
US20040204492A1 (en) Topical composition and method for treating seborrheic dermatitis
JPH10265365A (ja) ニキビ用皮膚外用剤
Fathi et al. Efficacy and Safety of Combination of Mometasone Furoate 0.1% Cream and Adapalene 0.1% Gel in Alopecia Areata
JP2013082631A (ja) 非侵襲的に皮膚の色素の除去を促進するための組成物
MX2007006059A (es) Composicion de crema desmanchadora de piel.
WO2006119540A1 (en) Preparation for treating psoriasis
WO2019132850A1 (en) Dermatologic and cosmetologic treatment compounds showing antiinflammatory and antipruritic characteristics having adjuvant interaction strontium salts and licorice combinations
JP2002003371A (ja) ステロイド５α−リダクターゼ活性阻害剤及びそれを有効成分とする医療用組成物、化粧料組成物、養毛料、皮膚障害治療剤
AU2006246350A1 (en) Preparation for treating psoriasis

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20160330

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20160330

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20161220

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20170912