JP2016190070A5 - - Google Patents
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- Publication number
- JP2016190070A5 JP2016190070A5 JP2016133994A JP2016133994A JP2016190070A5 JP 2016190070 A5 JP2016190070 A5 JP 2016190070A5 JP 2016133994 A JP2016133994 A JP 2016133994A JP 2016133994 A JP2016133994 A JP 2016133994A JP 2016190070 A5 JP2016190070 A5 JP 2016190070A5
- Authority
- JP
- Japan
- Prior art keywords
- coating
- catheter assembly
- water
- therapeutic agent
- hema
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000011248 coating agent Substances 0.000 claims 16
- 238000000576 coating method Methods 0.000 claims 16
- 229920000642 polymer Polymers 0.000 claims 9
- 239000003814 drug Substances 0.000 claims 8
- 229940124597 therapeutic agent Drugs 0.000 claims 8
- 102100026735 Coagulation factor VIII Human genes 0.000 claims 6
- 101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 claims 6
- WOBHKFSMXKNTIM-UHFFFAOYSA-N Hydroxyethyl methacrylate Chemical compound CC(=C)C(=O)OCCO WOBHKFSMXKNTIM-UHFFFAOYSA-N 0.000 claims 6
- 239000011159 matrix material Substances 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 229930012538 Paclitaxel Natural products 0.000 claims 5
- 239000002202 Polyethylene glycol Substances 0.000 claims 5
- 229960001592 paclitaxel Drugs 0.000 claims 5
- 229920001223 polyethylene glycol Polymers 0.000 claims 5
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 5
- 239000003125 aqueous solvent Substances 0.000 claims 4
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 claims 3
- 229910052740 iodine Inorganic materials 0.000 claims 3
- 239000011630 iodine Substances 0.000 claims 3
- 229920000036 polyvinylpyrrolidone Polymers 0.000 claims 3
- 235000013855 polyvinylpyrrolidone Nutrition 0.000 claims 3
- 239000001267 polyvinylpyrrolidone Substances 0.000 claims 3
- HKVAMNSJSFKALM-GKUWKFKPSA-N Everolimus Chemical compound C1C[C@@H](OCCO)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 HKVAMNSJSFKALM-GKUWKFKPSA-N 0.000 claims 2
- YNAVUWVOSKDBBP-UHFFFAOYSA-N Morpholine Chemical compound C1COCCN1 YNAVUWVOSKDBBP-UHFFFAOYSA-N 0.000 claims 2
- 238000010560 atom transfer radical polymerization reaction Methods 0.000 claims 2
- 239000012888 bovine serum Substances 0.000 claims 2
- 229960005167 everolimus Drugs 0.000 claims 2
- PNDPGZBMCMUPRI-UHFFFAOYSA-N iodine Chemical compound II PNDPGZBMCMUPRI-UHFFFAOYSA-N 0.000 claims 2
- 239000000178 monomer Substances 0.000 claims 2
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims 2
- 229960002930 sirolimus Drugs 0.000 claims 2
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims 2
- SMZOUWXMTYCWNB-UHFFFAOYSA-N 2-(2-methoxy-5-methylphenyl)ethanamine Chemical compound COC1=CC=C(C)C=C1CCN SMZOUWXMTYCWNB-UHFFFAOYSA-N 0.000 claims 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N 2-Propenoic acid Natural products OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 1
- 229920001577 copolymer Polymers 0.000 claims 1
- 238000003618 dip coating Methods 0.000 claims 1
- 238000001035 drying Methods 0.000 claims 1
- VOZRXNHHFUQHIL-UHFFFAOYSA-N glycidyl methacrylate Chemical group CC(=C)C(=O)OCC1CO1 VOZRXNHHFUQHIL-UHFFFAOYSA-N 0.000 claims 1
- 239000003999 initiator Substances 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- HNJBEVLQSNELDL-UHFFFAOYSA-N pyrrolidin-2-one Chemical compound O=C1CCCN1 HNJBEVLQSNELDL-UHFFFAOYSA-N 0.000 claims 1
- 210000005166 vasculature Anatomy 0.000 claims 1
- 229920002554 vinyl polymer Polymers 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12/712,134 US8128951B2 (en) | 2008-09-15 | 2010-02-24 | Local delivery of water-soluble or water-insoluble therapeutic agents to the surface of body lumens |
| US12/712,134 | 2010-02-24 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014142111A Division JP2014195736A (ja) | 2010-02-24 | 2014-07-10 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017125830A Division JP6466520B2 (ja) | 2010-02-24 | 2017-06-28 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016190070A JP2016190070A (ja) | 2016-11-10 |
| JP2016190070A5 true JP2016190070A5 (cg-RX-API-DMAC7.html) | 2016-12-22 |
| JP6169229B2 JP6169229B2 (ja) | 2017-07-26 |
Family
ID=43638759
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012554976A Active JP5781548B2 (ja) | 2010-02-24 | 2010-03-17 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
| JP2014142111A Withdrawn JP2014195736A (ja) | 2010-02-24 | 2014-07-10 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
| JP2016133994A Active JP6169229B2 (ja) | 2010-02-24 | 2016-07-06 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
| JP2017125830A Active JP6466520B2 (ja) | 2010-02-24 | 2017-06-28 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2012554976A Active JP5781548B2 (ja) | 2010-02-24 | 2010-03-17 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
| JP2014142111A Withdrawn JP2014195736A (ja) | 2010-02-24 | 2014-07-10 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017125830A Active JP6466520B2 (ja) | 2010-02-24 | 2017-06-28 | 水溶性又は不水溶性の治療剤の身体管腔表面への局所的送達 |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US8128951B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2538990B1 (cg-RX-API-DMAC7.html) |
| JP (4) | JP5781548B2 (cg-RX-API-DMAC7.html) |
| CN (2) | CN105664263A (cg-RX-API-DMAC7.html) |
| AU (3) | AU2010346621B2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2789565A1 (cg-RX-API-DMAC7.html) |
| HK (1) | HK1219908A1 (cg-RX-API-DMAC7.html) |
| NZ (1) | NZ601762A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2011106027A1 (cg-RX-API-DMAC7.html) |
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2010
- 2010-02-24 US US12/712,134 patent/US8128951B2/en active Active
- 2010-03-17 CN CN201610050061.8A patent/CN105664263A/zh active Pending
- 2010-03-17 EP EP10716921.1A patent/EP2538990B1/en active Active
- 2010-03-17 JP JP2012554976A patent/JP5781548B2/ja active Active
- 2010-03-17 WO PCT/US2010/027731 patent/WO2011106027A1/en not_active Ceased
- 2010-03-17 NZ NZ601762A patent/NZ601762A/en not_active IP Right Cessation
- 2010-03-17 CA CA2789565A patent/CA2789565A1/en not_active Abandoned
- 2010-03-17 CN CN2010800644973A patent/CN102781489A/zh active Pending
- 2010-03-17 AU AU2010346621A patent/AU2010346621B2/en not_active Ceased
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2011
- 2011-12-02 US US13/310,320 patent/US8563023B2/en active Active
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2013
- 2013-09-20 US US14/032,336 patent/US20140171864A1/en not_active Abandoned
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2014
- 2014-04-17 AU AU2014202149A patent/AU2014202149B2/en not_active Ceased
- 2014-07-10 JP JP2014142111A patent/JP2014195736A/ja not_active Withdrawn
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2016
- 2016-07-06 JP JP2016133994A patent/JP6169229B2/ja active Active
- 2016-07-06 HK HK16107852.4A patent/HK1219908A1/zh unknown
- 2016-08-05 AU AU2016210749A patent/AU2016210749B2/en not_active Ceased
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- 2017-06-28 JP JP2017125830A patent/JP6466520B2/ja active Active
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