JP2016102092A - Pest repelling efficacy enhancer, and pest repelling method by using pest repellent composition incorporating the same - Google Patents
Pest repelling efficacy enhancer, and pest repelling method by using pest repellent composition incorporating the same Download PDFInfo
- Publication number
- JP2016102092A JP2016102092A JP2014241597A JP2014241597A JP2016102092A JP 2016102092 A JP2016102092 A JP 2016102092A JP 2014241597 A JP2014241597 A JP 2014241597A JP 2014241597 A JP2014241597 A JP 2014241597A JP 2016102092 A JP2016102092 A JP 2016102092A
- Authority
- JP
- Japan
- Prior art keywords
- pest repellent
- pest
- efficacy enhancer
- repellent
- antibacterial
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Catching Or Destruction (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Description
本発明は、害虫忌避効力増強剤、及びこれを配合した害虫忌避組成物を用いる害虫忌避方法に関するものである。更に詳しくは、特に皮膚や衣服に処理される害虫忌避成分の害虫忌避効力を増強させ、衣服から露出した肌や衣服着用者の服の上からの害虫の被害から保護するために効果的な害虫忌避効力増強剤、及びこれを配合した害虫忌避組成物を用いる害虫忌避方法に関するものである。 The present invention relates to a pest repellent efficacy enhancer and a pest repellent method using a pest repellent composition containing the same. More specifically, the pests that are effective to enhance the pest repellent efficacy of the pest repellent components that are treated especially on the skin and clothes, and to protect them from the damage of the pests exposed on the skin and the clothes wearer's clothes. The present invention relates to a repellent efficacy enhancer and a pest repellent method using a pest repellent composition containing the same.
蚊、ブヨ、サシバエ等の害虫から人体等を守るための人体用害虫忌避剤は広く実用に供され、その忌避効力の向上、あるいは使用感の改善、刺激性の軽減を目的とした様々な改良品が提案されている。一方、人体の皮膚に対する症害を極力回避するために、害虫忌避剤を人体の皮膚に適用するのではなく、特開２００３−２６５２３号公報（特許文献１）や特開２０１０−２２２２７８号公報（特許文献２）のように、害虫忌避組成物を衣服に処理し害虫忌避効果を得ようとする試みもある。しかしながら、衣服に処理する方法では、忌避成分の処理ムラや処理量のバラツキが避けられず、蚊、ブヨ、サシバエ等のような飛翔害虫に対し満足のいく忌避効果が得られない場面が多いのが実情である。 Pest repellents for the human body to protect the human body from insect pests such as mosquitoes, gnats, and fly flies are widely used in practice, and various improvements aimed at improving their repellent efficacy, improving the feeling of use, and reducing irritation Goods have been proposed. On the other hand, in order to avoid illnesses on the human skin as much as possible, a pest repellent is not applied to the human skin, but JP-A-2003-26523 (Patent Document 1) and JP-A-2010-222278 ( There is also an attempt to obtain a pest repellent effect by treating a pest repellent composition on clothes as in Patent Document 2). However, in the method of treating clothes, uneven treatment of the repellent components and variations in the amount of treatment cannot be avoided, and there are many situations where satisfactory repellent effects cannot be obtained against flying pests such as mosquitoes, gnats, and fly flies. Is the actual situation.
ところで、最近話題に上った吸血害虫であるマダニ類は通常、野外の草むらや森林等に生息し、シカやイノシシ等の野生動物に寄生するが、犬に寄生する種類も知られている。マダニ類の成虫は、通りかかった人の上着に取り付いてから下着〜皮膚面に移行し、徘徊しながら寄生部位を探して咬着する。その後の吸血は産卵のために必要で、この際に様々な病原体を媒介させるベクターとなりうることが報告され、最近では、ウイルス感染症の一つである重症熱性血小板減少症候群（ＳＦＴＳ）との関連性が取り沙汰されている。
かかる現状を鑑み、当面のマダニ被害対策として、濃度が１０％程度のジエチルトルアミド（ディート）製剤を手袋や袖口にスプレーしたり、露出皮膚面に塗布する方法が提唱されている。また、特開平５−１７８７１２号公報（特許文献３）には、ベンジルホーメート、ベンジルアセテート、ベンジルプロピオネート等の化合物及びこれを主成分とする精油等を有効成分に用いたマダニの忌避剤が開示されているが、それらの効果は到底十分とは言えない。
By the way, ticks that are blood-sucking pests that have recently been talked about usually inhabit wild grasses and forests, and parasitize wild animals such as deer and wild boar, but are also known to parasitize dogs. The adult ticks move to the underwear-skin surface after attaching to the jacket of a person who passes by, searching for the parasitic site while wandering and biting. Subsequent blood sucking has been reported to be necessary for egg laying and can serve as a vector for mediating various pathogens. Recently, it has been associated with severe febrile thrombocytopenia syndrome (SFTS), one of viral infections. Sex is taken.
In view of the present situation, as a countermeasure against tick damage for the time being, methods have been proposed in which a diethyltoluamide (diet) preparation having a concentration of about 10% is sprayed on gloves or cuffs or applied to the exposed skin surface. JP-A-5-178712 (Patent Document 3) discloses a tick repellent using as an active ingredient a compound such as benzylformate, benzylacetate, benzylpropionate, and an essential oil containing the compound as a main component. However, the effect is not sufficient.
本発明は、害虫忌避成分の害虫忌避効力を増強させる成分を特定するのみならず、使用した場合には使用場所として肌やその周辺部はもとより、衣服に処理された時に当該衣服から露出したその周辺部をも吸血害虫からの被害から保護するために効果的な害虫忌避効力増強剤、及びこれを配合した害虫忌避組成物を用いる害虫忌避方法を提供しようとするものである。 The present invention not only identifies the component that enhances the pest repellent efficacy of the pest repellent component, but also when exposed to the skin and its surroundings as a place of use, when exposed to the clothing It is an object of the present invention to provide an insect pest repellent efficacy enhancer effective for protecting the peripheral portion from damage from blood-sucking pests, and a pest repellent method using a pest repellent composition containing the same.
本発明者らは、人体用忌避成分のより効率的な使用の検討を行うため、蚊、ブヨ、サシバエやマダニ等のような吸血害虫に対して、使用されている各種害虫忌避成分の効力をより高めるための物質の配合を検討した。そして、その結果、害虫忌避成分に対してその忌避効力をより増強させ得る忌避効力増強剤を見出し、これを応用することによって本発明を完成するに至ったものである。 In order to investigate more efficient use of human repellent components, the present inventors have demonstrated the effectiveness of various pest repellent components used against blood-sucking pests such as mosquitoes, gnats, horn flies and ticks. The composition of the substance to enhance it was examined. As a result, the present inventors have completed the present invention by finding a repellent efficacy enhancer that can further enhance the repellent efficacy of the pest repellent component and applying it.
本発明は、以下の構成が上記目的を達成するために優れた効果を奏することを見出したものである。
（１）抗菌性化合物から選ばれる１種以上であって、かつ、害虫忌避成分を添加した害虫忌避組成物に配合される前記害虫忌避成分の害虫忌避効力増強剤。
（２）前記害虫忌避成分が３−（Ｎ−ブチルアセトアミド）プロピオン酸エチル及び／又はＮ，Ｎ−ジエチルトルアミドからなる（１）に記載の害虫忌避効力増強剤。
（３）前記抗菌性化合物が、フェノール系抗菌剤、ベンゾチアゾール系抗菌剤及びイソチアゾリン系抗菌剤からなる１種以上である（１）又は（２）に記載の害虫忌避効力増強剤。
（４）前記抗菌性化合物が、前記害虫忌避成分に対し、０．００５〜０．３倍量配合されてなる（１）ないし（３）のいずれかに記載の害虫忌避効力増強剤。
（５）前記害虫忌避組成物が、前記３−（Ｎ−ブチルアセトアミド）プロピオン酸エチル０．５〜１０％を配合する（１）ないし（４）のいずれかに記載の害虫忌避効力増強剤。
（６）前記フェノール系抗菌剤、ベンゾチアゾール系抗菌剤及びイソチアゾリン系抗菌剤が、３−メチル−４−イソプロピルフェノール、オルト−フェニルフェノール、２−ｎ−オクチル−４−イソチアゾリン−３−オン、５−クロロ−２−メチル−４−イソチアゾリン−３−オン、２−メルカプトベンゾチアゾールから選ばれる１種以上である（１）ないし（５）のいずれかに記載の害虫忌避効力増強剤。
（７）（１）〜（６）に記載の忌避効力増強剤を用いた害虫忌避方法。
（８）前記（７）に記載の害虫忌避方法における対象が衣類であることを特徴する害虫忌避方法。
The present invention has been found that the following constitution has an excellent effect for achieving the above-mentioned object.
(1) The pest repellent efficacy enhancer of the pest repellent component, which is one or more selected from antibacterial compounds and is added to the pest repellent composition to which the pest repellent component is added.
(2) The pest repellent efficacy enhancer according to (1), wherein the pest repellent component comprises ethyl 3- (N-butylacetamide) propionate and / or N, N-diethyltoluamide.
(3) The pest repellent efficacy enhancer according to (1) or (2), wherein the antibacterial compound is one or more of a phenolic antibacterial agent, a benzothiazole antibacterial agent and an isothiazoline antibacterial agent.
(4) The pest repellent efficacy enhancer according to any one of (1) to (3), wherein the antibacterial compound is blended in an amount of 0.005 to 0.3 times the pest repellent component.
(5) The pest repellent efficacy enhancer according to any one of (1) to (4), wherein the pest repellent composition contains 0.5 to 10% of the ethyl 3- (N-butylacetamido) propionate.
(6) The phenolic antibacterial agent, benzothiazole antibacterial agent and isothiazoline antibacterial agent are 3-methyl-4-isopropylphenol, ortho-phenylphenol, 2-n-octyl-4-isothiazoline-3-one, 5 The pest repellent efficacy enhancer according to any one of (1) to (5), which is at least one selected from -chloro-2-methyl-4-isothiazolin-3-one and 2-mercaptobenzothiazole.
(7) A pest repellent method using the repellent efficacy enhancer according to (1) to (6).
(8) The pest repellent method, wherein the target in the pest repellent method according to (7) is clothing.
本発明に記載の害虫忌避効力増強剤を用いた害虫忌避組成物を使用することで、通常の害虫忌避効力が増強されることはもちろん、さらにこれらの害虫忌避効力増強剤は抗菌作用を持つことから、使用時における発汗の際の各種の菌が発生するいやな臭いを抑えることが出来るため、大変実用的である。
さらに、本発明の害虫忌避組成物における、害虫忌避効力の増強効果は、組成物を直接塗布した場所への効果のみならず、塗付した場所の周辺部分での忌避効果についても更なる増強効果が認められるとの効果も認められた。
By using the pest repellent composition using the pest repellent efficacy enhancer described in the present invention, not only the normal pest repellent efficacy is enhanced, but also these pest repellent efficacy enhancers have antibacterial action Therefore, it is very practical because it can suppress the unpleasant odor that causes various bacteria during sweating during use.
Furthermore, in the pest repellent composition of the present invention, the effect of enhancing the pest repellent effect is not only the effect on the place where the composition is directly applied, but also the repellent effect on the peripheral part of the applied place. The effect was also recognized.
本発明の剤型としては、一般的な各種の剤型を使用することが出来る。一般的な剤型としては、エアゾール剤、ポンプスプレー剤、ジェル剤、害虫忌避組成物をシートに含浸し、シートタイプとしたもの、害虫忌避組成物を入れてロールオンタイプとしたもの、各種の界面活性剤などを添加し乳液タイプとしたものが挙げられる。 Various general dosage forms can be used as the dosage form of the present invention. Common dosage forms include aerosols, pump sprays, gels, pest repellent compositions impregnated into sheets to make sheet types, pest repellent compositions containing roll-on types, and various interfaces The thing made into emulsion type by adding an activator etc. is mentioned.
エアゾール剤として使用する場合には、本発明に記載の害虫忌避組成物を原液として用い、これに噴射剤として、ジメチルエーテル、ＨＦＯ１２３４ｚｅや液化石油ガスなど液化ガスや窒素ガス、炭酸ガスなどの圧縮ガスや、若しくはこれらの２種以上を混合して用いることも出来る。 When used as an aerosol agent, the pest repellent composition described in the present invention is used as a stock solution, and as a propellant, a liquefied gas such as dimethyl ether, HFO1234ze or liquefied petroleum gas, a compressed gas such as nitrogen gas or carbon dioxide gas, Alternatively, two or more of these can be mixed and used.
本発明で用いられる抗菌性化合物としては、各種の一般的な抗菌性化合物が用いられる。抗菌性化合物としては、通常のフェノール系抗菌成分や四級アンモニウム塩の抗菌成分、イソチアゾリン系抗菌成分など各種の化合物が用いられる。これは単独で用いてもよいし、１種又は２種以上を混合して使用してもよい。
フェノール系抗菌剤としては、一般的なフェノール系抗菌成分であれは、特に限定はされないものの、３−メチル−４−イソプロピルフェノール、オルト−フェニルフェノールなどが例示される。ベンゾチアゾール系抗菌剤としては、５−クロロ−２−メチル−４−イソチアゾリン−３−オン、２−メルカプトベンゾチアゾールが例示される。さらにイソチアゾリン系抗菌剤としては、２−ｎ−オクチル−４−イソチアゾリン−３−オン、５−クロロ−２−メチル−４−イソチアゾリン−３−オンが挙げられるが、これらに限定されるものではない。
As the antibacterial compound used in the present invention, various general antibacterial compounds are used. As the antibacterial compound, various compounds such as a normal phenolic antibacterial component, an antibacterial component of quaternary ammonium salt, an isothiazoline antibacterial component are used. These may be used alone or in combination of one or more.
The phenolic antibacterial agent is not particularly limited as long as it is a general phenolic antibacterial component, and examples thereof include 3-methyl-4-isopropylphenol and ortho-phenylphenol. Examples of the benzothiazole antibacterial agent include 5-chloro-2-methyl-4-isothiazolin-3-one and 2-mercaptobenzothiazole. Further, examples of the isothiazoline-based antibacterial agent include 2-n-octyl-4-isothiazolin-3-one and 5-chloro-2-methyl-4-isothiazolin-3-one, but are not limited thereto. .
害虫忌避成分としても特に限定されるものではないが、一般的な害虫忌避成分である例えば、ディート、３−（Ｎ−ｎ−ブチル−Ｎ−アセチル）アミノプロピオン酸エチルエステル、１−メチルプロピル ２−（２−ヒドロキシエチル）−１−ピペリジンカルボキシラート、ｐ−メンタン−３，８−ジオール、が挙げられるが、その中でも３−（Ｎ−ブチルアセトアミド）プロピオン酸エチルやディートなどが好適である。さらに、これらは単独で用いてもよいし、両方を混合し、混合忌避成分として用いてもよい。特に、ディートにおいては、一部の化学繊維に対しては、影響を及ぼす場合もあるのに対し、３−（Ｎ−ブチルアセトアミド）プロピオン酸エチルが繊維などに対する影響はほとんど認められないことから、衣類に対する害虫忌避成分として特に適している。 Although it does not specifically limit also as a pest repellent component, For example, Deat, 3- (Nn-butyl-N-acetyl) aminopropionic acid ethyl ester, 1-methylpropyl 2 which is a general pest repellent component Examples include-(2-hydroxyethyl) -1-piperidinecarboxylate and p-menthane-3,8-diol. Among them, ethyl 3- (N-butylacetamido) propionate and diet are preferable. Furthermore, these may be used alone, or both may be mixed and used as a mixed repellent component. In particular, since diet may affect some chemical fibers, ethyl 3- (N-butylacetamido) propionate has almost no effect on the fibers. It is particularly suitable as a pest repellent component for clothing.
本発明の害虫忌避組成物に用いられる溶剤としては、各種の溶剤を使用することが出来る。溶剤しては、水や各種のアルコールやグリコール系溶剤などを用いたりすることも出来る。本発明の害虫忌避組成物は気温の高いときに用いられることから、速乾性の溶剤は特に好ましい、速乾性の溶剤としては、各種の低級アルコールを挙げることが出来る。低級アルコールとしては、エタノール、イソプロパノールやプロパノールが挙げられる。 Various solvents can be used as the solvent used in the pest repellent composition of the present invention. As the solvent, water, various alcohols, glycol solvents and the like can be used. Since the pest repellent composition of the present invention is used when the temperature is high, a fast-drying solvent is particularly preferred, and examples of the quick-drying solvent include various lower alcohols. Examples of the lower alcohol include ethanol, isopropanol, and propanol.
本発明の害虫忌避組成物には、必要に応じて消臭剤や香料を添加することも出来る。 A deodorant and a fragrance | flavor can also be added to the pest repellent composition of this invention as needed.
本発明の害虫忌避組成物には、各種の界面活性剤を添加することも出来る。界面活性剤としては、アニオン界面活性剤、非イオン界面活性剤、両性界面活性剤が使用できる。アニオン界面活性剤としては、例えば脂肪酸石けん、アルキルベンゼンスルホン酸塩、直鎖アルキルベンゼンスルホン酸塩、アルキル硫酸塩、アルファオレフィンスルホン酸塩、アルキルリン酸エステル塩、ポリオキシエチレンアルキルエーテル硫酸塩、ポリオキシエチレンアルキルエーテルカルボン酸塩、ポリオキシエチレンアルキルフェニルエーテル硫酸塩、ポリオキシエチレンアルキルエーテルりん酸塩、アルキルスルホコハク酸塩、ポリオキシエチレンアルキルスルホコハク酸塩などが挙げられる。非イオン界面活性剤としては、例えばポリオキシアルキレンアルキルエーテル、ポリオキシエチレンアルキルフェニルエーテル、ポリオキシエチレン高級脂肪酸エステル、ポリオキシエチレンソルビタン脂肪酸エステル、ポリオキシエチレングリセリン脂肪酸エステル、ポリオキシエチレン硬化ヒマシ油、ヤシ油脂肪酸ジエタノールアミド、脂肪酸アルカノールアミド、アミンオキシドなどが挙げられる。両性界面活性剤としてはアルキルカルボベタイン、アルキルアミドカルボベタイン、アルキルスルホベタイン、アルキルヒドロキシスルホベタイン、アルキルアミドスルホベタイン、アルキルアミドヒドロキシスルホベタイン等が挙げられる。 Various surfactants can also be added to the pest repellent composition of the present invention. As the surfactant, an anionic surfactant, a nonionic surfactant, and an amphoteric surfactant can be used. Examples of the anionic surfactant include fatty acid soap, alkylbenzene sulfonate, linear alkylbenzene sulfonate, alkyl sulfate, alpha olefin sulfonate, alkyl phosphate ester salt, polyoxyethylene alkyl ether sulfate, polyoxyethylene Examples thereof include alkyl ether carboxylates, polyoxyethylene alkyl phenyl ether sulfates, polyoxyethylene alkyl ether phosphates, alkyl sulfosuccinates, polyoxyethylene alkyl sulfosuccinates, and the like. Nonionic surfactants include, for example, polyoxyalkylene alkyl ether, polyoxyethylene alkylphenyl ether, polyoxyethylene higher fatty acid ester, polyoxyethylene sorbitan fatty acid ester, polyoxyethylene glycerin fatty acid ester, polyoxyethylene hydrogenated castor oil, Examples include coconut oil fatty acid diethanolamide, fatty acid alkanolamide, and amine oxide. Examples of amphoteric surfactants include alkyl carbobetaines, alkylamide carbobetaines, alkylsulfobetaines, alkylhydroxysulfobetaines, alkylamide sulfobetaines, alkylamide hydroxysulfobetaines, and the like.
本発明の効果を阻害しない限りにおいて他種溶剤も使用可能である。かかる溶剤としては、水の外、ｎ−パラフィン、イソパラフィン等の炭化水素系溶剤、プロピレングリコール、１，３−ブチレングリコール、ジプロピレングリコール、ジエチレングリコールモノブチルエーテル等のグリコール類やグリコールエーテル類、ケトン系溶剤、エステル系溶剤等が挙げられる。 Other solvents can be used as long as the effects of the present invention are not impaired. Such solvents include water, hydrocarbon solvents such as n-paraffin and isoparaffin, glycols such as propylene glycol, 1,3-butylene glycol, dipropylene glycol and diethylene glycol monobutyl ether, glycol ethers, and ketone solvents. And ester solvents.
本発明における対象害虫としては、一般的な吸血性害虫や刺咬性害虫については使用可能である。より具体的には、対象害虫としては、一般的な蚊類であるアカイエカ、ヒトスジシマカ、チカエイカや各種のアブ類、ブユ、ヌカカ、やトコジラミや各種のダニ類としてイエダニやマダニ、不快害虫であるユスリカ類、チョウバエ類、クロヤマアリ、トビイロシワアリ、イエヒメアリ、アミメアリ、アルゼンチンアリ等のアリ類、アシナガバチ、スズメバチなどのハチ類などが挙げられる。 As the target pests in the present invention, general blood-sucking pests and biting pests can be used. More specifically, the target pests include common mosquitoes such as mosquitoes, Aedes albopictus, chikaeika, various abu species, blackfish, nukaka, bed bugs and various mites, mite, ticks, and chironomid, an unpleasant pest Ants such as mosquitoes, butterflies, black ants, long-tailed ants, house peas, sand ants, and Argentine ants, and bees such as wasps and wasps.
次に具体的な実施例ならびに試験例に基づき、本発明の害虫忌避効力増強剤、及びこれを配合した害虫忌避組成物を用いる害虫忌避方法について更に詳細に説明する。
但し、本発明は決してこれらに限定される物ではない。
Next, the pest repellent method using the pest repellent efficacy enhancer of the present invention and the pest repellent composition containing the same will be described in more detail based on specific examples and test examples.
However, the present invention is not limited to these.
３−（Ｎ−ｎ−ブチル−Ｎ−アセチル）アミノプロピオン酸エチルエステル（以下、IR3535と記す） 4g、3-メチル-4-イソプロピルメチルフェノール（IPMP）0.4ｇ、及び香料0.1gにエタノール47ｇを加え、溶解し、更に水を加え、全量で100ｍLとした。これをポンプ式スプレーのヘッドが付いた容器に入れ本発明の害虫忌避効力増強剤を得た。
以下、同様に表１に示す害虫忌避組成物を作成し、試験に供試した。
3- (Nn-butyl-N-acetyl) aminopropionic acid ethyl ester (hereinafter referred to as IR3535) 4 g, 3-methyl-4-isopropylmethylphenol (IPMP) 0.4 g, and fragrance 0.1 g were added 47 g of ethanol. In addition, it was dissolved and water was added to make a total volume of 100 mL. This was put in a container with a pump spray head to obtain the pest repellent efficacy enhancer of the present invention.
Hereinafter, the pest repellent composition shown in Table 1 was similarly prepared and used for the test.
23ｃｍ×60ｃｍ×45ｃｍの透明アクリル容器（2か所に両手を入れる穴をあけたもの）を準備し、容器内にアカイエカ雌成虫30匹を放った。被験者の前腕に実施例あるいは比較例の上記で得た供試薬剤（0.5ｇ）を処理した綿布（30×30cm）をまきつけて、アクリル容器内に前腕を入れた。5分間、腕に係留した供試昆虫を計数して、忌避効果を評価した。なお、忌避率は無処理の綿布をまきつけて、同様の操作を行った際の5分間の係留した供試昆虫を計数して、以下の式から算出した。試験は3回繰り返して、その平均値を算出した。
忌避率(％)＝（無処理綿布をまきつけた腕に係留した虫−処理綿布をまきつけた腕に係留した虫）／無処理綿布をまきつけた腕に係留した虫 × １００
A 23 cm × 60 cm × 45 cm transparent acrylic container (having two holes in both places) was prepared, and 30 female squids were released into the container. A cotton cloth (30 × 30 cm) treated with the reagent agent (0.5 g) obtained in the above example or comparative example was applied to the forearm of the subject, and the forearm was placed in an acrylic container. Test insects moored on the arm for 5 minutes were counted to evaluate the repellent effect. The repelling rate was calculated from the following formula by counting untouched test cloths for 5 minutes when untreated cotton cloth was applied and performing the same operation. The test was repeated three times and the average value was calculated.
Repelling rate (%) = (insect anchored to arm with untreated cotton cloth-insect anchored to arm with untreated cotton cloth) / insect anchored to arm with untreated cotton cloth × 100
試験結果より、忌避成分単独の処方の薬剤を用いるより、抗菌成分を用いたものの方がより効果が上がることが判った。
以上のことから、抗菌成分が忌避効果のアップに寄与していることが明らかとなった。
From the test results, it was found that the antibacterial component was more effective than the repellent component alone.
From the above, it became clear that the antibacterial component contributes to the improvement of the repellent effect.
23ｃｍ×60ｃｍ×45ｃｍの透明アクリル容器（2か所に両手を入れる穴をあけたもの）を準備し、容器内にアカイエカ雌成虫30匹を放った。被験者の前腕に実施例あるいは比較例の供試薬剤（0.5ｇ）を処理した綿布（30×30cm）をまきつけて、アクリル容器内に前腕を入れた。5分間、腕に係留した供試昆虫を計数して、忌避効果を評価した。なお、忌避率は無処理の綿布をまきつけて、同様の操作を行った際の5分間の係留した供試昆虫を計数して、実施例１と同様に算出した。試験は3回繰り返して、その平均値を算出した。
A 23 cm × 60 cm × 45 cm transparent acrylic container (having two holes in both places) was prepared, and 30 female squids were released into the container. A cotton cloth (30 × 30 cm) treated with the reagent reagent of Example or Comparative Example (0.5 g) was applied to the forearm of the subject, and the forearm was placed in an acrylic container. Test insects moored on the arm for 5 minutes were counted to evaluate the repellent effect. The repellent rate was calculated in the same manner as in Example 1 by counting untreated cotton cloths, counting the number of test insects moored for 5 minutes when the same operation was performed. The test was repeated three times and the average value was calculated.
上記の結果より、実施例に示した抗菌成分との併用による忌避効果は忌避剤単独使用の場合に比較して、初期から一定時間に渡り効果が持続することが認められた。
From the above results, it was confirmed that the repellent effect due to the combined use with the antibacterial component shown in the Examples was sustained for a certain time from the beginning as compared with the case of using the repellent alone.
試験方法
23ｃｍ×60ｃｍ×45ｃｍの透明アクリル容器（2か所に両手を入れる穴をあけたもの）を準備し、容器内にアカイエカ雌成虫30匹を放った。7.5×30cmの綿布を4枚用意し、そのうち2枚に実施例および比較例に記載した供試薬剤1ｇを処理した。それらの綿布を前腕に処理綿布と無処理綿布が交互になるようまきつけ、透明アクリル板容器内に入れた。5分間、腕に処理した処理綿布および無処理綿布に係留した供試昆虫を計数して、忌避効果を評価した。なお、忌避率は4枚とも無処理の綿布をまきつけて、同様の操作を行った際の5分間の係留した供試昆虫を計数して、実施例１と同様に算出した。
Test method
A 23 cm × 60 cm × 45 cm transparent acrylic container (having two holes in both places) was prepared, and 30 female squids were released into the container. Four 7.5 × 30 cm cotton fabrics were prepared, and 2 of them were treated with 1 g of the reagent agent described in Examples and Comparative Examples. These cotton cloths were wound around the forearm so that treated cotton cloth and untreated cotton cloth were alternately placed in a transparent acrylic board container. The test insects moored on the treated cotton cloth and untreated cotton cloth treated on the arm for 5 minutes were counted to evaluate the repellent effect. The repelling rate was calculated in the same manner as in Example 1 by counting four untreated cotton cloths and counting the 5-minute moored test insects when the same operation was performed.
実施例に記載の薬剤は、塗付した部分以外の近辺でも忌避効果が認められた。これに対して、忌避剤のみしか使用していない比較例４では、無処理部分の効果は低く、抗菌成分を使用した場合との効力の差は明らかとなった。 The drugs described in the Examples were found to have a repellent effect even in the vicinity other than the applied part. On the other hand, in Comparative Example 4 in which only the repellent was used, the effect of the untreated portion was low, and the difference in efficacy from the case where the antibacterial component was used was clarified.
本発明は、人体及び衣類用の虫よけの効力増強剤のみならず、各種の虫よけ剤に利用可能である。
INDUSTRIAL APPLICABILITY The present invention can be used for various insect repellents as well as insect repellent efficacy enhancers for human bodies and clothes.
Claims (8)
The pest repellent method according to claim 7, wherein the object in the pest repellent method is clothing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014241597A JP6497909B2 (en) | 2014-11-28 | 2014-11-28 | Pest repellent efficacy enhancer and pest repellent method using pest repellent composition containing the same |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014241597A JP6497909B2 (en) | 2014-11-28 | 2014-11-28 | Pest repellent efficacy enhancer and pest repellent method using pest repellent composition containing the same |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016102092A true JP2016102092A (en) | 2016-06-02 |
| JP2016102092A5 JP2016102092A5 (en) | 2018-08-09 |
| JP6497909B2 JP6497909B2 (en) | 2019-04-10 |
Family
ID=56088329
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014241597A Active JP6497909B2 (en) | 2014-11-28 | 2014-11-28 | Pest repellent efficacy enhancer and pest repellent method using pest repellent composition containing the same |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6497909B2 (en) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018138532A (en) * | 2017-02-24 | 2018-09-06 | 大日本除蟲菊株式会社 | Biting/stinging damage prevention method of bee and horsefly |
| JP2018138531A (en) * | 2017-02-24 | 2018-09-06 | 大日本除蟲菊株式会社 | Biting/stinging damage prevention method of bee and horsefly |
| KR20190029503A (en) | 2016-07-15 | 2019-03-20 | 라이온 가부시키가이샤 | Insect repellent composition, and insect repellent method |
| CN109497060A (en) * | 2018-05-22 | 2019-03-22 | 中国科学院昆明植物研究所 | Application of the carvacrol analog in mosquito repellent product |
| JP2022078226A (en) * | 2017-04-17 | 2022-05-24 | 大日本除蟲菊株式会社 | Spray product |
| JP2022176243A (en) * | 2018-06-27 | 2022-11-25 | 大日本除蟲菊株式会社 | Spray for preventing oviposition of clothing pest, and clothing pest oviposition prevention method |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53109938A (en) * | 1977-03-09 | 1978-09-26 | Takasago Corp | Insecticide |
| JPS5432620A (en) * | 1977-08-16 | 1979-03-10 | Katsuraya Fine Goods | Insecticidal agent |
| JPS59204102A (en) * | 1983-05-07 | 1984-11-19 | Earth Chem Corp Ltd | Insect pest repellent |
| JPH045201A (en) * | 1990-04-20 | 1992-01-09 | Mitsubishi Petrochem Co Ltd | Mite-repellent aqueous resin emulsion composition |
| JPH05208902A (en) * | 1991-03-19 | 1993-08-20 | Nippon Terupen Kagaku Kk | Mosquito-repelling agent |
| JPH11346635A (en) * | 1998-06-09 | 1999-12-21 | Daiwa Kagaku Kogyo Kk | Repellent composition for rice weevil |
| JP2001199806A (en) * | 2000-01-17 | 2001-07-24 | S T Chem Co Ltd | Repellent against adult of fiber insect pest and method for repelling adult of fiber insect pest |
| JP2002068906A (en) * | 2000-08-30 | 2002-03-08 | Asahi Kasei Corp | Insect pest-repellent |
| JP2007502860A (en) * | 2003-04-24 | 2007-02-15 | ヴァンダービルト ユニバースィティ | Compositions and methods for controlling insects |
| JP2007126376A (en) * | 2005-11-02 | 2007-05-24 | Earth Chem Corp Ltd | Indoor mite-repelling activity enhancer |
| JP2013006823A (en) * | 2011-05-26 | 2013-01-10 | Lion Corp | Insect pest repellent for fiber product, and method for repelling insect pest |
-
2014
- 2014-11-28 JP JP2014241597A patent/JP6497909B2/en active Active
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53109938A (en) * | 1977-03-09 | 1978-09-26 | Takasago Corp | Insecticide |
| JPS5432620A (en) * | 1977-08-16 | 1979-03-10 | Katsuraya Fine Goods | Insecticidal agent |
| JPS59204102A (en) * | 1983-05-07 | 1984-11-19 | Earth Chem Corp Ltd | Insect pest repellent |
| JPH045201A (en) * | 1990-04-20 | 1992-01-09 | Mitsubishi Petrochem Co Ltd | Mite-repellent aqueous resin emulsion composition |
| JPH05208902A (en) * | 1991-03-19 | 1993-08-20 | Nippon Terupen Kagaku Kk | Mosquito-repelling agent |
| JPH11346635A (en) * | 1998-06-09 | 1999-12-21 | Daiwa Kagaku Kogyo Kk | Repellent composition for rice weevil |
| JP2001199806A (en) * | 2000-01-17 | 2001-07-24 | S T Chem Co Ltd | Repellent against adult of fiber insect pest and method for repelling adult of fiber insect pest |
| JP2002068906A (en) * | 2000-08-30 | 2002-03-08 | Asahi Kasei Corp | Insect pest-repellent |
| JP2007502860A (en) * | 2003-04-24 | 2007-02-15 | ヴァンダービルト ユニバースィティ | Compositions and methods for controlling insects |
| JP2007126376A (en) * | 2005-11-02 | 2007-05-24 | Earth Chem Corp Ltd | Indoor mite-repelling activity enhancer |
| JP2013006823A (en) * | 2011-05-26 | 2013-01-10 | Lion Corp | Insect pest repellent for fiber product, and method for repelling insect pest |
Non-Patent Citations (1)
| Title |
|---|
| MARC C. DOLAN ET AL.: "A Review of Arthropod Repellents", ACS SYMPOSIUM SERIES, vol. 1090, JPN6018030119, 13 December 2011 (2011-12-13), pages 1 - 19, ISSN: 0003908455 * |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20190029503A (en) | 2016-07-15 | 2019-03-20 | 라이온 가부시키가이샤 | Insect repellent composition, and insect repellent method |
| JP2018138532A (en) * | 2017-02-24 | 2018-09-06 | 大日本除蟲菊株式会社 | Biting/stinging damage prevention method of bee and horsefly |
| JP2018138531A (en) * | 2017-02-24 | 2018-09-06 | 大日本除蟲菊株式会社 | Biting/stinging damage prevention method of bee and horsefly |
| JP2022078226A (en) * | 2017-04-17 | 2022-05-24 | 大日本除蟲菊株式会社 | Spray product |
| JP7293434B2 (en) | 2017-04-17 | 2023-06-19 | 大日本除蟲菊株式会社 | spray products |
| CN109497060A (en) * | 2018-05-22 | 2019-03-22 | 中国科学院昆明植物研究所 | Application of the carvacrol analog in mosquito repellent product |
| JP2022176243A (en) * | 2018-06-27 | 2022-11-25 | 大日本除蟲菊株式会社 | Spray for preventing oviposition of clothing pest, and clothing pest oviposition prevention method |
Also Published As
| Publication number | Publication date |
|---|---|
| JP6497909B2 (en) | 2019-04-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP6497909B2 (en) | Pest repellent efficacy enhancer and pest repellent method using pest repellent composition containing the same | |
| US11039623B2 (en) | Arthropod control formulations and methods | |
| US7902256B2 (en) | Pest treatment composition | |
| RU2113119C1 (en) | Agent for insect frightening away | |
| JP7293434B2 (en) | spray products | |
| US10743535B2 (en) | Insecticide for flight-capable pests | |
| TW201946533A (en) | Insect pest repellent and insect pest repellent product | |
| WO2001089503A1 (en) | Pest treatment composition | |
| EA008175B1 (en) | Acetals as insect repellant agents | |
| US7988985B2 (en) | Pest repellent compositions and methods | |
| CN104349672A (en) | Killing of bed bugs | |
| WO2004036998A1 (en) | Insect repellent based on a mixture of essential oils | |
| JP4627634B2 (en) | Indoor dust mite repellent | |
| JP6325943B2 (en) | Aerosol for preventing insect pest behavior and method for preventing insect pest behavior using the same | |
| JP6095427B2 (en) | Tick repellent efficacy enhancer and tick repellent method using tick repellent composition containing the same | |
| JP2014205648A (en) | Ixodes repelling efficacy promoter, method of repelling ixodes using ixodes repelling composition containing the same | |
| JP6708377B2 (en) | Lice repellent | |
| JP2020158474A (en) | Female lice repellent | |
| JP2003026523A (en) | Method for protecting skin from blood sucker and method for repelling blood sucker | |
| JP6836930B2 (en) | How to prevent bee and bug bites | |
| AU2014201934B2 (en) | Composition and method for amphibian euthanasia | |
| JPS6051441B2 (en) | insect repellent composition | |
| JP7257354B2 (en) | How to avoid lice | |
| JP2019048783A (en) | Flying pest tracking inhibitor | |
| Baker et al. | Sodium Lauryl Sulfate Profile |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20171017 |
|
| RD02 | Notification of acceptance of power of attorney |
Free format text: JAPANESE INTERMEDIATE CODE: A7422 Effective date: 20180611 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20180626 |
|
| A977 | Report on retrieval |
Free format text: JAPANESE INTERMEDIATE CODE: A971007 Effective date: 20180622 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20180807 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20181004 |
|
| A131 | Notification of reasons for refusal |
Free format text: JAPANESE INTERMEDIATE CODE: A131 Effective date: 20181030 |
|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20181120 |
|
| TRDD | Decision of grant or rejection written | ||
| A01 | Written decision to grant a patent or to grant a registration (utility model) |
Free format text: JAPANESE INTERMEDIATE CODE: A01 Effective date: 20190312 |
|
| A61 | First payment of annual fees (during grant procedure) |
Free format text: JAPANESE INTERMEDIATE CODE: A61 Effective date: 20190312 |
|
| R150 | Certificate of patent or registration of utility model |
Ref document number: 6497909 Country of ref document: JP Free format text: JAPANESE INTERMEDIATE CODE: R150 |
|
| R250 | Receipt of annual fees |
Free format text: JAPANESE INTERMEDIATE CODE: R250 |