JP2016069343A5 - - Google Patents
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- Publication number
- JP2016069343A5 JP2016069343A5 JP2014201707A JP2014201707A JP2016069343A5 JP 2016069343 A5 JP2016069343 A5 JP 2016069343A5 JP 2014201707 A JP2014201707 A JP 2014201707A JP 2014201707 A JP2014201707 A JP 2014201707A JP 2016069343 A5 JP2016069343 A5 JP 2016069343A5
- Authority
- JP
- Japan
- Prior art keywords
- amyloid
- beta protein
- lys
- pro
- met
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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- IRVONVRHHJXWTK-RWMBFGLXSA-N Met-Lys-Pro Chemical compound CSCC[C@@H](C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@@H]1C(=O)O)N IRVONVRHHJXWTK-RWMBFGLXSA-N 0.000 claims description 8
- 239000003795 chemical substances by application Substances 0.000 claims description 8
- 108010022588 methionyl-lysyl-proline Proteins 0.000 claims description 8
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 8
- 102000013455 Amyloid beta-Peptides Human genes 0.000 claims description 5
- 108010090849 Amyloid beta-Peptides Proteins 0.000 claims description 5
- 208000012902 Nervous system disease Diseases 0.000 claims description 5
- 230000006269 (delayed) early viral mRNA transcription Effects 0.000 claims description 4
- 230000005978 brain dysfunction Effects 0.000 claims description 4
- 235000013305 food Nutrition 0.000 claims description 4
- 239000004480 active ingredient Substances 0.000 claims description 3
- 239000005018 casein Substances 0.000 claims description 2
- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims description 2
- 235000021240 caseins Nutrition 0.000 claims description 2
- 239000000203 mixture Substances 0.000 claims description 2
- 208000024827 Alzheimer disease Diseases 0.000 claims 2
- 235000013361 beverage Nutrition 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 230000000069 prophylactic effect Effects 0.000 description 1
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014201707A JP6344796B2 (ja) | 2014-09-30 | 2014-09-30 | 高齢者用アルツハイマー型認知症改善剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2014201707A JP6344796B2 (ja) | 2014-09-30 | 2014-09-30 | 高齢者用アルツハイマー型認知症改善剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2018095342A Division JP6589011B2 (ja) | 2018-05-17 | 2018-05-17 | 脳機能障害改善用経口組成物 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2016069343A JP2016069343A (ja) | 2016-05-09 |
| JP2016069343A5 true JP2016069343A5 (enExample) | 2016-12-28 |
| JP6344796B2 JP6344796B2 (ja) | 2018-06-20 |
Family
ID=55863992
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014201707A Active JP6344796B2 (ja) | 2014-09-30 | 2014-09-30 | 高齢者用アルツハイマー型認知症改善剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP6344796B2 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2018057346A (ja) * | 2016-10-07 | 2018-04-12 | 森永乳業株式会社 | カゼイン酵素処理物及びその製造方法 |
| JP7062460B2 (ja) * | 2018-02-16 | 2022-05-06 | 森永乳業株式会社 | 発酵乳の製造方法 |
| SG11202007786WA (en) | 2018-02-16 | 2020-09-29 | Morinaga Milk Industry Co Ltd | Composition and composition for lowering blood pressure and/or reducing neutral fats |
| JP2019142791A (ja) * | 2018-02-16 | 2019-08-29 | 森永乳業株式会社 | 血圧降下用及び/又は中性脂肪低減用の組成物 |
| JP6589011B2 (ja) * | 2018-05-17 | 2019-10-09 | 森永乳業株式会社 | 脳機能障害改善用経口組成物 |
| JP7368949B2 (ja) * | 2019-03-13 | 2023-10-25 | キリンホールディングス株式会社 | 脳内グルタミン酸濃度の増加抑制用組成物 |
| JP7344722B2 (ja) * | 2019-09-04 | 2023-09-14 | 森永乳業株式会社 | 構成行為改善用組成物 |
| JP6964635B2 (ja) * | 2019-09-04 | 2021-11-10 | 森永乳業株式会社 | 見当識改善用組成物 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5098889A (en) * | 1990-09-17 | 1992-03-24 | E. R. Squibb & Sons, Inc. | Method for preventing or inhibiting loss of cognitive function employing a combination of an ace inhibitor and a drug that acts at serotonin receptors |
| DE10105041A1 (de) * | 2001-02-05 | 2002-08-14 | Tell Pharm Ag Hergiswil | Tripeptide und Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
| DE10105039A1 (de) * | 2001-02-05 | 2002-08-08 | Tell Pharm Ag Hergiswil | Tripeptid-Derivate für die Behandlung neurodegenerativer Krankheiten |
| CA2468039C (en) * | 2001-11-21 | 2011-01-04 | Morinaga Milk Industry Co., Ltd. | Novel peptide having angiotensin converting enzyme inhibitory effect |
| JPWO2005011736A1 (ja) * | 2003-07-30 | 2006-09-14 | 株式会社 東北テクノアーチ | アルツハイマー病の予防および/または治療剤 |
| EP1684783A4 (en) * | 2003-10-23 | 2009-07-08 | Neuren Pharmaceuticals Ltd | NEUROPROTECTIVE EFFECTS OF GLY-PRO-GLU AFTER INTRAVENOUS INFUSION |
| JP2007523122A (ja) * | 2004-02-20 | 2007-08-16 | ノバルティス アクチエンゲゼルシャフト | 神経変性障害および認知障害の処置のためのdpp−iv阻害剤 |
| JP2011136932A (ja) * | 2009-12-28 | 2011-07-14 | Calpis Co Ltd | 脳機能改善用組成物および脳機能を改善する方法 |
| JP5926363B2 (ja) * | 2012-02-22 | 2016-05-25 | 森永乳業株式会社 | ジペプチジルペプチダーゼ−iv阻害剤 |
-
2014
- 2014-09-30 JP JP2014201707A patent/JP6344796B2/ja active Active
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