WO2017018686A3 - 마나산틴 a 또는 마나산틴 b를 포함하는 비알코올성 지방간 질환 예방 또는 치료용 조성물 - Google Patents
마나산틴 a 또는 마나산틴 b를 포함하는 비알코올성 지방간 질환 예방 또는 치료용 조성물 Download PDFInfo
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- WO2017018686A3 WO2017018686A3 PCT/KR2016/007395 KR2016007395W WO2017018686A3 WO 2017018686 A3 WO2017018686 A3 WO 2017018686A3 KR 2016007395 W KR2016007395 W KR 2016007395W WO 2017018686 A3 WO2017018686 A3 WO 2017018686A3
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- manassantin
- fatty liver
- alcoholic fatty
- treatment
- liver disease
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- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Animal Behavior & Ethology (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Abstract
본 발명은 마나산틴 A(manassantin A) 또는 마나산틴 B(manassantin B)을 포함하는 비알코올성 지방간 질환 예방 또는 치료용 조성물에 관한 것으로, 본 발명의 마나산틴 A(manassantin A) 또는 마나산틴 B(manassantin B)을 포함하는 비알코올성 지방간 질환 예방 또는 치료용 조성물은 종래 합성 약제 조성물이 유발하는 심혈관작용, 중추작용, 간장장애 및 신장장애 등 여러 부작용이 없으며, 비알코올성 지방간 질환에 의한 염증 감소, 비알코올성 지방간 진행 및 전이 억제, 간 내 지질축적 억제, 항 세포사멸효과 및 세포의 자식작용(autophagy) 활성촉진 효과를 가지고 있으므로, 비알코올성 지방간 예방 및/또는 치료용 약학적 조성물 또는 비알코올성 지방간 및/또는 개선용 건강기능성 식품 조성물로 유용하게 활용될 수 있다.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020150106051A KR20170013086A (ko) | 2015-07-27 | 2015-07-27 | 마나산틴 a 또는 마나산틴 b를 포함하는 비알코올성 지방간 질환 예방 또는 치료용 조성물 |
KR10-2015-0106051 | 2015-07-27 |
Publications (2)
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WO2017018686A2 WO2017018686A2 (ko) | 2017-02-02 |
WO2017018686A3 true WO2017018686A3 (ko) | 2017-04-06 |
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PCT/KR2016/007395 WO2017018686A2 (ko) | 2015-07-27 | 2016-07-07 | 마나산틴 a 또는 마나산틴 b를 포함하는 비알코올성 지방간 질환 예방 또는 치료용 조성물 |
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KR (1) | KR20170013086A (ko) |
WO (1) | WO2017018686A2 (ko) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
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KR102106991B1 (ko) * | 2019-06-07 | 2020-05-06 | 충북대학교 산학협력단 | 아스타잔틴을 유효 성분으로 포함하는 알코올성 간 질환의 치료 또는 예방용 조성물 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN102327368A (zh) * | 2010-09-06 | 2012-01-25 | 成都地奥制药集团有限公司 | 三白草根茎总有效部位及其制备方法和用途 |
KR20150026972A (ko) * | 2013-08-30 | 2015-03-11 | 한국생명공학연구원 | 삼백초 추출물 및 이의 분획물로부터 분리된 화합물을 유효성분으로 함유하는 항바이러스용 약학적 조성물 |
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2015
- 2015-07-27 KR KR1020150106051A patent/KR20170013086A/ko active Application Filing
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2016
- 2016-07-07 WO PCT/KR2016/007395 patent/WO2017018686A2/ko active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102327368A (zh) * | 2010-09-06 | 2012-01-25 | 成都地奥制药集团有限公司 | 三白草根茎总有效部位及其制备方法和用途 |
KR20150026972A (ko) * | 2013-08-30 | 2015-03-11 | 한국생명공학연구원 | 삼백초 추출물 및 이의 분획물로부터 분리된 화합물을 유효성분으로 함유하는 항바이러스용 약학적 조성물 |
Non-Patent Citations (3)
Title |
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CHANG, J. S. ET AL.: "Manassant in A and B From Saururus Chinensis Inhibit Interleukin-6-induced Signal Transducer and Activator of Transcription 3 Activation in Hep3B Cells", JOURNAL OF PHARMACOLOGICAL SCIENCES, vol. 115, no. 1, 2011, pages 84 - 88, XP055374660 * |
KIM, J. Y. ET AL.: "Inhibition of Phenotypic and Functional Maturation of Dendritic Cells by Manassant in A", JOURNAL OF PHARMACOLOGICAL SCIENCES, vol. 109, no. 4, 2009, pages 583 - 592, XP055374662 * |
LEE, M. K. ET AL.: "Antifibrotic Activity of Manassant in B from Saururus Chinensis in HSC-T6 Hepatic Stellate Cells", NATURAL PRODUCT SCIENCES, vol. 14, no. 2, 2008, pages 118 - 121, XP053005995 * |
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Publication number | Publication date |
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WO2017018686A2 (ko) | 2017-02-02 |
KR20170013086A (ko) | 2017-02-06 |
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