JP2016022451A - Body fluid storage container - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide a body fluid storage container which properly takes out a desired component in a body fluid centrifugally separated.SOLUTION: A body fluid storage container may store a body fluid centrifugally separated and includes: a first storage part 720 having a first cavity part 721 that stores the body fluid; a second storage part 730 detachably attached to the first storage part 720 and having a second cavity part 731 that stores the body fluid with the first cavity part 721, the second storage part 730 in which an inner diameter of the second cavity part 731 is smaller than an inner diameter of the first cavity part 721; and a lid part 740 which closes an opening of the second storage part 730 which is located opposite to the side attached to the first storage part 720.SELECTED DRAWING: Figure 4

Description

  The present invention relates to a body fluid container for housing body fluid.

  2. Description of the Related Art Conventionally, a body fluid container that can contain body fluids such as blood and urine used for a test for diagnosing a human health condition is known. The body fluid is collected by the body fluid collector and then stored in the body fluid container.

  Patent Document 1 discloses a technique for extracting blood cell parts and plasma parts after separating blood cells and plasma, which are constituents of blood, by centrifuging blood contained in a tube body that is a body fluid container. Yes. By examining and analyzing the blood cell portion and the plasma portion thus taken out, it becomes possible to diagnose the human health condition.

JP-A-9-141135

  By the way, improvement of the collection method and inspection method of body fluid advances, and the amount of collection of body fluid used for inspection tends to be reduced. In such a case, in order to prevent a decrease in test accuracy, it is necessary to have a configuration of a body fluid container that can appropriately extract a desired component (for example, blood cells) to be tested from a small amount of collected body fluid. In order to take out a desired component, it can be considered that a body fluid container containing body fluid is set in a centrifuge and centrifuged for each component. However, when centrifuging using a conventional bodily fluid container, it is necessary to insert a micropipette into the bodily fluid container in which a plurality of composition components are stacked after centrifugation to take out a desired component. When it did in this way, there existed a problem that the said component and another composition component would mix.

  In addition, the thin protrusion part which can accommodate some blood cells of the blood after centrifugation is integrally molded at the front-end | tip of the tubular body described in patent document 1. FIG. Such molding is usually performed using a mold. However, stress concentration tends to occur at a molding portion of a thin protrusion on the molding by the mold, so that it is difficult to integrally mold the protrusion.

  Then, this invention is made | formed in view of these points, and it aims at providing the bodily fluid container which can take out the desired component in the centrifuged bodily fluid appropriately.

  In the first aspect of the present invention, a body fluid container that can store a body fluid to be centrifuged, separated into a first housing portion having a first cavity portion for housing the body fluid, and the first housing portion. A second housing part that is mounted so as to have a second cavity part that houses the body fluid together with the first cavity part, wherein the inner diameter of the second cavity part is smaller than the inner diameter of the first cavity part A bodily fluid container is provided, comprising: a second housing portion; and a lid portion that closes an opening of the second housing portion on the side opposite to the mounting side of the first housing portion.

  The second housing part may be press-fitted and attached to an opening located on the second housing part side of the first housing part.

  The second housing part may be formed of a material harder than the first housing part.

  The first housing part may be formed of a flexible material.

  The second housing portion is formed in a cylindrical shape, and a housing portion selected from a small-diameter housing portion and a large-diameter housing portion having different inner diameters is mounted on the first housing portion as the second housing portion. Good.

  The outer diameter of the large diameter accommodating part may be the same size as the outer diameter of the small diameter accommodating part.

  The body fluid is blood including plasma and blood cells, and when the body fluid is centrifuged, the first storage portion may store the plasma and the second storage portion may store the blood cells.

  The first storage unit and the second storage unit can store a separating agent, and when the body fluid is centrifuged, the separating agent is located at a connection position of the first cavity portion and the second cavity portion. May be.

  According to a second aspect of the present invention, there is provided a body fluid container comprising an inner container capable of accommodating a body fluid to be centrifuged, and an outer container containing the inner container, wherein the inner container Has a first housing part having a first cavity part for housing the body fluid and a second cavity part separably attached to the first housing part and for housing the body fluid together with the first housing part. The second housing portion, the second housing portion having an inner diameter of the second cavity portion smaller than the inner diameter of the first cavity portion, and the mounting side of the second housing portion to the first housing portion There is provided a body fluid container including a lid portion that closes an opening located on the opposite side.

  According to the present invention, there is an effect that a desired component in a centrifuged body fluid can be appropriately taken out.

It is a figure which shows the structure of the bodily fluid collection apparatus 2000 which concerns on one Embodiment of this invention. It is a figure which shows the structure of the bodily fluid container 700 which concerns on one Embodiment. It is a side view of the outer side container 701 which concerns on one Embodiment. It is a side view of the inner side container 702 which concerns on one Embodiment. 6 is a cross-sectional view of the vicinity of the outer lid portion 712 and the upper lid portion 722 when the outer lid portion 712 and the upper lid portion 722 are closed. FIG. FIG. 10 is a cross-sectional view showing an example of a mounting state of the second storage portion 730 to the first storage portion 720. It is a figure for demonstrating an example of a small diameter accommodating part and a large diameter accommodating part. It is a schematic diagram which shows an example of the state of the blood and the separating agent in the inner container 702 after centrifugation. It is a flowchart which shows an example of the flow from blood collection to a test | inspection.

<Outline of body fluid collection device>
An outline of a body fluid sampling device according to one embodiment of the present invention will be described with reference to FIGS. 1 and 2.

  FIG. 1 is a diagram showing a configuration of a body fluid sampling device 2000 according to one embodiment. FIG. 2 is a diagram illustrating a configuration of the body fluid container 700 according to the embodiment. The body fluid sampling device 2000 includes a body fluid collector 600 and a body fluid container 700. The body fluid container 700 has a cylindrical shape, but FIG. 1 shows an internal state in which the body fluid container 700 is inserted into the body fluid collector 600.

  The body fluid collector 600 includes a suction unit 601, a main body unit 602, a blocking unit 603, and a pressure generating unit 604. The suction part 601, the main body part 602, the blocking part 603, and the pressure generating part 604 are made of, for example, a transparent or translucent resin material.

  When the user immerses the tip of the suction unit 601 in the body fluid to be collected, the body fluid is sucked into the suction unit 601 and accumulated in the suction unit 601 by capillary action. The suction part 601 has two hollow parts 613a and 613b, and absorbs body fluid through either one.

  The main body portion 602 has a ventilation path through which a gas for discharging the body fluid sucked by the suction portion 601 is passed. Specifically, the air passage causes the gas to flow toward the suction unit 601 by the pressure generated by the pressure generation unit 604 to move the gas for discharging body fluid to the suction unit 601 side. For example, the body fluid accumulated in the suction part 601 is discharged by the air taken in from the outside flowing through the ventilation path 621 (ventilation paths 621a and 621b).

  The blocking part 603 is provided between the main body part 602 and the suction part 601. The blocking portion 603 is formed with a tapered cavity having a smaller inner diameter on the main body 602 side than the inner diameter on the suction portion 601 side. The blocking unit 603 blocks the body fluid sucked by the suction unit 601 from flowing into the main body unit 602.

  The suction unit 601 and the blocking unit 603 may be detachably mounted. In such a case, it is possible to select and attach a suction part and a blocking part having a size corresponding to the amount of blood to be collected.

  The body fluid container 700 stores the chemical liquid injected at the time of manufacture in order to prevent the destruction of the body fluid and the body fluid discharged from the body fluid collector 600. Specifically, the body fluid container 700 includes an outer container 701 and an inner container 702 as shown in FIG. 2, and stores the chemical solution and the body fluid in the inner container 702 accommodated in the outer container 701. . The user presses the pressure generating unit 604 in a state where the body fluid collecting device 600 in a state where the body fluid is accumulated in the suction unit 601 is inserted into the body fluid container 700, whereby the body fluid accumulated in the suction unit 601 is stored in the inner container 702. Can be accommodated.

<Configuration of body fluid container 700>
A detailed configuration of the body fluid container 700 will be described with reference to FIGS. 3 and 4. Below, after demonstrating the structure of the outer side container 701 which comprises the bodily fluid container 700, the structure of the inner side container 702 is demonstrated.

(Outer container 701)
FIG. 3 is a side view of the outer container 701 according to one embodiment. The outer container 701 houses the inner container 702. The outer container 701 includes an outer container 710, an outer lid 712, and an outer coupling part 714.

  The outer housing part 710 has an outer cavity part 711 that houses the inner container 702. The outer cavity 711 is formed inside the outer housing 710 and is a slightly larger cavity than the inner container 702.

  In addition, the outer container 710 has a fixing portion 713 that fixes the inner container 702 to the outer cavity 711 by contacting a later-described protrusion 723 formed in the inner container 702. The fixing portion 713 is an annular region formed on the inner wall of the outer housing portion 710 in the horizontal direction orthogonal to the direction in which the inner housing 702 is inserted.

  The outer lid portion 712 is an outer cavity portion 711 in a state where the inner receptacle 702 in a state where the first cavity portion 721 is closed by an upper lid portion 722 of the inner receptacle 702 described later is inserted into the outer cavity portion 711. (See FIG. 5). That is, it has a double sealed structure. The inner diameter of the outer lid portion 712 is larger than the outer diameter of the outer housing portion 710 at the opening side end portion of the outer cavity portion 711. 5 is a cross-sectional view of the vicinity of the outer lid portion 712 and the upper lid portion 722 in a state where the outer lid portion 712 and the upper lid portion 722 are closed.

  The outer joint portion 714 is a member that is formed into a shape that can be folded without breaking, and joins the outer lid portion 712 and the outer housing portion 710.

(Inner container 702)
FIG. 4 is a side view of the inner container 702 according to one embodiment. The inner container 702 stores body fluid to be centrifuged. The inner container 702 includes a first housing part 720, an upper lid part 722, an inner coupling part 724, a second housing part 730, and a lower lid part 740. In the following, blood containing blood cells and plasma will be described as an example of the body fluid.

  The first storage unit 720 includes a first cavity 721 into which a body fluid collector 600 that collects blood can be inserted, and stores a chemical solution for preventing blood destruction and blood collected by the body fluid collector 600. The first accommodating part 720 has a shape that can be accommodated in the outer cavity part 711, and protrudes toward the outer accommodating part 710 in the horizontal direction perpendicular to the direction in which the first accommodating part 720 is inserted into the outer accommodating part 710. Projecting portion 723.

  The upper lid part 722 closes the first cavity part 721 of the first accommodating part 720 in a state where the body fluid collector 600 is not inserted. The upper lid portion 722 includes a first upper lid portion 722a having a thickness corresponding to the width of the protruding portion 723, and a second upper lid portion 722b having a diameter smaller than that of the first upper lid portion 722a.

  In a state where the upper lid portion 722 closes the first cavity portion 721, the first upper lid portion 722a is in contact with the protruding portion 723, and the second upper lid portion 722b is blood in the first cavity portion 721 with respect to the protruding portion 723. Is located on the side where it is housed. Since the first upper lid portion 722a and the second upper lid portion 722b have such a shape, in the state where the upper lid portion 722 closes the first accommodation portion 720, the first accommodation portion 720 and the upper lid portion Since the path connecting the space outside 722 becomes long, it becomes easy to prevent evaporation of blood and chemicals. Further, even in a state before the blood is stored in the first cavity 721, it is possible to prevent a decrease in the chemical liquid stored in advance in the body fluid container.

  The inner coupling portion 724 is a member that is coupled to the upper lid portion 722 and the first accommodating portion 720 and is processed into a shape that can be bent without breaking. The inner coupling portion 724 is provided with unevenness formed continuously on at least one surface (see FIG. 5).

  The 1st accommodating part 720, the upper cover part 722, and the inner side coupling part 724 are comprised, for example by using ABS resin or polycarbonate (PC) as a forming member. By using ABS resin or polycarbonate (PC) that hardly absorbs liquid, it is possible to prevent blood from being absorbed into the first storage portion 720 and the upper lid portion 722 when blood is stored in the first storage portion 720. . Note that, as in the case where the chemical solution is stored only for a short period (for example, about one month), polypropylene (PP) or the like is used as a forming member for the first storage portion 720, the upper lid portion 722, and the inner coupling portion 724 depending on the application. Other materials may be used.

  The second accommodating portion 730 has a second cavity portion 731 that accommodates blood together with the first cavity portion 721. The second housing part 730 is formed in a cylindrical shape, and the inner diameter of the second cavity part 731 is smaller than the inner diameter of the first cavity part 721. The second cavity 731 stores blood including blood cells and plasma before centrifugation, but has a function of storing only blood cells of blood cells and plasma after centrifugation. The axial length of the second cavity portion 731 is set so that the second cavity portion 731 accommodates blood cells after centrifugation. Note that the second cavity 731 may slightly contain plasma on the upper side.

  FIG. 6 is a cross-sectional view illustrating an example of a state in which the second storage portion 730 is attached to the first storage portion 720. In the present embodiment, the second housing part 730 is detachably mounted on the first housing part 720. That is, the second housing part 730 is a separate member from the first housing part 720. In such a case, since the axial length of the second storage portion 730 can be increased compared to the case where the second storage portion and the first storage portion are integrally molded, even if the amount of blood cells is large It can be reliably accommodated. When the first housing portion and the second housing portion are integrally formed by injection molding or the like, it is difficult to appropriately form the second housing portion having a long axial direction. This is because the integral molding is performed using a mold, but stress concentration tends to occur in the molding portion of the second housing portion having a small inner diameter upon molding by the mold, and therefore the second housing portion may be damaged. Because there is.

  The second housing part 730 is press-fitted and attached to a mounted part 726 that is an opening located on the second housing part 730 side of the first housing part 720. Thereby, since the connection part of the 2nd accommodating part 730 and the 1st accommodating part 720 after mounting adheres, blood will evaporate from the connecting part of the 1st accommodating part 720 and the 2nd accommodating part 730 which are separate members. Can be prevented.

  In the present embodiment, the first housing portion 720 can be configured to mount different types of second housing portions 730. Specifically, as the second accommodating portion 730, an accommodating portion selected from a small diameter accommodating portion and a large diameter accommodating portion having different inner diameters as shown in FIG. 7 is mounted on the first accommodating portion 720. Here, the two accommodating portions are described as an example, but the present invention is not limited to this. For example, one accommodating portion selected from three or more accommodating portions having different inner diameters is the first accommodating portion. 720 may be attached.

  FIG. 7 is a diagram for explaining an example of a small-diameter accommodating portion and a large-diameter accommodating portion. FIG. 7A shows a large-diameter accommodating portion 730A, and FIG. 7B shows a small-diameter accommodating portion 730B. Each of the large-diameter accommodating portion 730A and the small-diameter accommodating portion 730B includes a large-diameter cavity portion 731A and a small-diameter cavity portion 731B that accommodate blood.

  The inner diameter D2 of the large diameter accommodating portion 730A is smaller than the inner diameter D3 of the small diameter accommodating portion 730B. On the other hand, the axial length L of the large-diameter accommodating portion 730A and the small-diameter accommodating portion 730B is the same size. Accordingly, the amount of blood that can be accommodated in the large-diameter accommodating portion 730A (large-diameter cavity portion 731A) is larger than the amount of blood that can be accommodated in the small-diameter accommodating portion 730B (small-diameter cavity portion 731B). In other words, after centrifugation, the amount of blood cells that can be accommodated in the large diameter accommodating portion 730A is larger than the amount of blood cells that can be accommodated in the small diameter accommodating portion 730B. Therefore, by attaching the large-diameter container 730A or the small-diameter container 730B according to the amount of blood cells required for the examination, plasma and blood cells are appropriately stored in the first container and the second container after centrifugation, respectively. It becomes possible to make it.

  The outer diameter D1 of the large diameter accommodating portion 730A may be the same size as the outer diameter D1 of the small diameter accommodating portion 730B. Specifically, as shown in FIG. 7, the outer diameter of the large-diameter accommodating portion 730A and the outer diameter of the small-diameter accommodating portion 730B are reduced by making the thickness t1 of the large-diameter accommodating portion 730A smaller than the thickness t2 of the small-diameter accommodating portion 730B. The diameter can be the same size. In such a case, the large-diameter accommodating portion 730A and the small-diameter accommodating portion 730B can be press-fitted and attached to the attached portion 726 without changing the structure of the attached portion 726 (FIG. 6) of the first accommodating portion 720.

  In the above description, the outer diameter D1 of the large-diameter accommodating portion 730A and the small-diameter accommodating portion 730B is the same size, but is not limited thereto. For example, the outer diameter of the large diameter accommodating portion 730A may be larger than the outer diameter of the small diameter accommodating portion 730B.

In the above description, the length L in the axial direction of the large-diameter accommodating portion 730A and the small-diameter accommodating portion 730B is the same size, but is not limited thereto. For example, the axial length of the large diameter accommodating portion 730A may be larger than the axial length of the small diameter accommodating portion 730B. In such a case, the amount of blood cells that can be stored can be changed in accordance with the second storage portion to be mounted.

  In the above description, the second housing portion 730 is press-fitted and attached to the first housing portion 720. However, the present invention is not limited to this. For example, the structure which press-fits the 1st accommodating part 720 in the 2nd accommodating part 730 may be sufficient. In addition, a member for fixing the second housing part 730 to the first housing part 720 may be provided separately. That is, any configuration may be used as long as the second housing portion 730 is in close contact with the first housing portion 720.

  In the present embodiment, when the blood in the inner container 702 is centrifuged, blood cells having a high specific gravity are stored in the lower second storage part 730, and plasma having a low specific gravity is stored in the upper first storage part 720. Is done. Thus, when plasma and blood cells are stored in different storage portions after centrifugation, the plasma and blood cells can be easily taken out individually. For example, by removing the second container 730 containing blood cells from the inner container 702, only blood cells located on the bottom side of the inner container 702 after centrifugation can be easily obtained without using a micropipette. It can be taken out. In addition, when the second storage portion 730 is removed, the plasma is not mixed with blood cells when the plasma is discharged from the opening of the attached portion 726 or when the plasma is taken out by the micropipette. Can be taken out properly.

  The second housing part 730 may be formed of a material harder than the first housing part 720 formed of ABS resin or the like as described above. For example, the second housing portion 730 is made of glass, hard polycarbonate, or the like. In such a case, since the rigidity of the second housing portion 730 is strong, when the second housing portion 730 is press-fitted into the first housing portion 720, the second housing portion 730 is attached to the first housing portion 720. Since it is easy to be inserted into 726, the second housing portion 730 is easily attached to the attachment portion 726.

  The first housing part 720 may be formed of a flexible material. In such a case, when the second housing portion 730 is press-fitted into the first housing portion 720, the mounted portion 726 of the first housing portion 720 is easily pressed and expanded by the second housing portion 730. 2 It becomes easy to mount the accommodating portion 730 on the mounted portion 726.

As shown in FIG. 6, the lower lid portion 740 closes the opening of the second housing portion 730 that is located on the side opposite to the mounting side of the first housing portion 720. The lower lid portion 740 functions as a stopper that prevents the blood (blood cells after centrifugation) from being stored in the second storage portion 730. The lower lid part 740 is detachably attached to the second housing part 730. For example, a convex portion 741 is press-fitted and attached to the lower lid portion 740 so as to be in close contact with the second housing portion 730.
The lower lid portion 740 may be a lid in which a concave portion (not shown) serving as a liquid reservoir is formed on the surface on the second cavity portion 731 side. In the liquid reservoir, when a drug (for example, a washing liquid) is stored in the inner container 702, the drug is stored. In addition, since the blood cells after centrifugation are also stored in the recess, the storage capacity of the second storage portion 730 can be increased.

  The first storage unit 720 and the second storage unit 730 may store a separating agent. The separating agent is accommodated in the inner container 702 together with the blood before centrifugation. The separating agent exhibits so-called thixotropic properties. Thixotropy is a property exhibited by an intermediate material between a plastic solid such as a gel and a non-Newtonian liquid such as a sol. Such a separating agent changes from a gel state to a liquid phase at the time of centrifugation, moves between a blood cell portion and a plasma portion, and returns to a gel state after centrifugation. For this reason, the separating agent can keep a state between the plasma stored in the first storage unit 720 and the blood cells stored in the second storage unit 730 in a blocked state.

  FIG. 8 is a schematic diagram showing an example of the state of blood and separation agent in the inner container 702 after centrifugation. When the blood is centrifuged, the separating agent (the separating agent 790 shown in FIG. 8) is located at the connection position between the first cavity portion 721 and the second cavity portion 731. In such a case, after centrifugation, the plasma is accommodated only in the first cavity portion 721 and the blood cells are accommodated only in the second cavity portion 731, so that it is easy to take out the plasma and blood cells separately thereafter. That is, by removing the second storage portion 730, only blood cells can be taken out.

  In addition, since the separating agent has the thixotropy described above, it does not flow out from the opening of the mounted portion 726 even if the second storage portion 730 is removed after centrifugation. Further, since the separating agent fills the opening of the mounted portion 726, the plasma stored in the first storage portion 720 does not flow out of the opening of the mounted portion 726. That is, the separating agent functions as a stopper.

<An example of the flow from blood collection to testing>
Conventionally, centrifugation of blood using a centrifuge has been performed by an analysis organization that performs inspection and analysis. However, the centrifugal separator of the analysis engine is expensive and the running cost is high, so that cost reduction is required.

  In response to such a request, if the body fluid container 700 having the above-described configuration is used, blood is centrifuged with an inexpensive centrifuge at a facility other than the analysis engine (for example, a pharmacy), and then the analysis engine is used. It is possible to provide services for inspection and analysis. Thereby, since the use of the centrifuge in an analysis engine can be reduced, a running cost can be reduced. An example of such a service flow will be described with reference to FIG.

  FIG. 9 is a flowchart showing an example of a flow from blood collection to examination. In this service, a user who desires a blood test receives a body fluid collector 600 at a pharmacy or the like and collects blood (step S102). That is, the user sucks blood to be collected by the suction unit 601 of the body fluid collector 600.

  Next, the user or a clerk of the pharmacy discharges the blood from the body fluid collector 600 to the body fluid container 700 (step S104). That is, the store clerk or the like presses the pressure generator 604 of the body fluid collector 600 in a state where the body fluid collector 600 is inserted into the body fluid container 700 (specifically, the inner container 702). The accumulated blood is discharged to the body fluid container 700. Here, the separating agent is also stored in the body fluid container 700 before or after the blood is discharged to the body fluid container 700.

  Next, the store clerk sets the body fluid container 700 in a centrifuge installed in the pharmacy, and centrifuges the blood stored in the body fluid container 700 (step S106). It is assumed that conditions such as the rotation speed when performing the centrifugation are set in advance. When centrifugation is performed, due to the specific gravity difference between blood cells and plasma in blood, for example, as shown in FIG. 8, blood cells are stored in the second storage unit 730, and plasma is stored in the first storage unit 720, respectively. The Centrifugation may be performed with the outer container 701 containing the inner container 702 set in the centrifuge, or with only the inner container 702 set in the centrifuge. .

  The body fluid container 700 after the centrifugation is transported to an analysis organization that performs blood examination / analysis (step S108). Then, in the analysis engine, the second storage unit 730 attached to the first storage unit 720 is removed (step S110). That is, the second accommodating portion 730 that has been press-fitted is removed by being pulled out in a direction opposite to the mounting direction.

  Next, blood cells are taken out from the second storage unit 730 (step S112). Specifically, first, the lower lid portion 740 that closes the lower opening is removed from the second accommodating portion 730. And the blood cell accommodated in the 2nd accommodating part 730 is discharged | emitted through a lower opening. As a result, only blood cells can be taken out without using an instrument such as a micropipette.

  Next, extraction of the plasma from the first storage unit 720 is performed (step S114). Specifically, first, the upper lid 722 that closes the upper opening is opened. Then, an instrument such as a micropipette is inserted through the upper opening, and the plasma is aspirated and removed. Note that the plasma may be discharged from the opening of the mounted portion of the first housing portion 720. In such a case, a micropipette becomes unnecessary.

  Next, the analysis organization performs inspection / analysis on the extracted plasma and blood cells (step S116). Thereby, the health state of the user from whom the blood was collected can be determined.

  In the above-described service, even a pharmacy clerk who is not skilled in blood centrifuge can easily set the body fluid container 700 in the centrifuge and easily perform the centrifuge. Can grasp. For this reason, it becomes possible to carry out the centrifugation of blood, which has been performed in an analysis organization so far, in a pharmacy or the like.

<Summary>
As described above, the body fluid container 700 according to this embodiment has the second cavity portion 731 that contains the body fluid (specifically, blood) together with the first cavity portion 721 as shown in FIG. The housing portion 730 includes a lower lid portion 740 that closes an opening located on the side opposite to the mounting side of the second housing portion 730 to the first housing portion 720. The second housing part 730 is detachably attached to the first housing part 720, and the inner diameter of the second cavity part 731 is smaller than the inner diameter of the first cavity part 721.

  In such a case, since the axial length of the second storage portion 730 can be increased compared to the case where the second storage portion and the first storage portion are integrally molded, even if the amount of blood cells is large It can be appropriately accommodated in the second accommodating portion 730. Then, by removing the second storage portion 730 from the first storage portion 720 and opening the lower lid portion 740, blood cells in the blood can be easily taken out. In particular, the workability is greatly improved as compared with the case where blood cells are sucked and taken out by a conventional micropipette or the like.

  In the above description, the body fluid container 700 includes the inner container 702 that stores blood and the outer container 701 that stores the inner container 702, but the present invention is not limited thereto. For example, the body fluid container 700 may include only the inner container 702 and may not include the outer container.

  In the above description, blood has been described as an example of body fluid, but the present invention is not limited to this. For example, the body fluid may be urine. In such a case, blood cells in urine and the like are stored in the second storage unit 730 after centrifugation, so that urine blood cells can be easily taken out.

  As mentioned above, although this invention was demonstrated using embodiment, the technical scope of this invention is not limited to the range as described in the said embodiment. It will be apparent to those skilled in the art that various modifications or improvements can be added to the above embodiment. It is apparent from the scope of the claims that the embodiments added with such changes or improvements can be included in the technical scope of the present invention.

700 Body fluid container 701 Outer container 702 Inner container 720 First container 721 First cavity 726 Mounted part 730 Second container 730A Large diameter container 730B Small diameter container 731 Second cavity 740 Lower lid part 2000 Body fluid collection device

Claims (9)

A body fluid container capable of housing a body fluid to be centrifuged,
A first housing portion having a first cavity for housing the body fluid;
A second housing part that is detachably mounted in the first housing part and has a second cavity part that houses the body fluid together with the first cavity part, wherein an inner diameter of the second cavity part is the first A second accommodating portion smaller than the inner diameter of the cavity portion;
A lid portion for closing an opening of the second housing portion located on the side opposite to the mounting side to the first housing portion;
A body fluid container. The second housing portion is press-fitted and attached to an opening located on the second housing portion side of the first housing portion.
The body fluid container according to claim 1. The second housing part is formed of a material harder than the first housing part,
The body fluid container according to claim 1 or 2. The first housing part is formed of a flexible material.
The body fluid container according to any one of claims 1 to 3. The second accommodating portion is formed in a cylindrical shape,
As the second housing portion, a housing portion selected from a small-diameter housing portion and a large-diameter housing portion having different inner diameters is attached to the first housing portion.
The body fluid container according to any one of claims 1 to 4. The outer diameter of the large-diameter accommodating portion is the same size as the outer diameter of the small-diameter accommodating portion.
The body fluid container according to claim 5. The body fluid is blood including plasma and blood cells,
When the body fluid is centrifuged, the first storage unit stores the plasma, and the second storage unit stores the blood cells.
The body fluid container according to any one of claims 1 to 6. The first storage portion and the second storage portion can store a separating agent,
When the bodily fluid is centrifuged, the separating agent is located at a connection position between the first cavity and the second cavity,
The body fluid container according to any one of claims 1 to 7. An inner container capable of containing a body fluid to be centrifuged;
An outer container that houses the inner container;
A body fluid container comprising:
The inner container is
A first housing portion having a first cavity for housing the body fluid;
A second housing portion that is detachably mounted in the first housing portion and has a second cavity portion that houses the body fluid together with the first housing portion, wherein an inner diameter of the second cavity portion is the first A second accommodating portion smaller than the inner diameter of the cavity portion;
A lid portion for closing an opening of the second housing portion located on the side opposite to the mounting side to the first housing portion;
A body fluid container.

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