JP6836433B2 - Body fluid container - Google Patents

Body fluid container Download PDF

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JP6836433B2
JP6836433B2 JP2017057370A JP2017057370A JP6836433B2 JP 6836433 B2 JP6836433 B2 JP 6836433B2 JP 2017057370 A JP2017057370 A JP 2017057370A JP 2017057370 A JP2017057370 A JP 2017057370A JP 6836433 B2 JP6836433 B2 JP 6836433B2
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accommodating
sealing portion
body fluid
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space
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JP2018159643A (en
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みゆき 山川
みゆき 山川
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みゆき 山川
みゆき 山川
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Description

本発明は、体液を収容するための体液収容器に関する。 The present invention relates to a body fluid container for accommodating body fluid.

従来、人の健康状態を診断するための検査に用いる血液・尿等の体液を収容することができる体液収容器が知られている。体液収容器に収容された体液を検査するために、採取された体液から検査対象の所望の成分（例えば、血球等）を抽出する必要がある。特許文献１には、分離剤を入れた体液収容器内の体液を遠心分離機で遠心分離することにより、血漿と血球とを分離する技術が開示されている。 Conventionally, a body fluid container capable of accommodating body fluids such as blood and urine used for a test for diagnosing a human health condition has been known. In order to test the body fluid contained in the body fluid container, it is necessary to extract a desired component (for example, blood cells) to be tested from the collected body fluid. Patent Document 1 discloses a technique for separating plasma and blood cells by centrifuging the body fluid in the body fluid container containing the separating agent with a centrifuge.

特開２０１６−２２４５１号公報Japanese Unexamined Patent Publication No. 2016-22451

しかし、分離剤を用いる場合、体液収容器内の体液を遠心分離する前に、分離剤を体液収容器に入れる作業が必要であった。また、遠心分離後の体液成分（例えば血清と血球）を体液収容器から採取する際に、分離された体液成分が混合してしまうおそれがあった。 However, when a separating agent is used, it is necessary to put the separating agent into the body fluid container before centrifuging the body fluid in the body fluid container. In addition, when the body fluid components (for example, serum and blood cells) after centrifugation are collected from the body fluid container, the separated body fluid components may be mixed.

そこで、本発明はこれらの点に鑑みてなされたものであり、分離剤を用いることなく体液を複数の成分に分離した状態を維持できる体液収容器を提供することを目的とする。 Therefore, the present invention has been made in view of these points, and an object of the present invention is to provide a body fluid container capable of maintaining a state in which a body fluid is separated into a plurality of components without using a separating agent.

本発明の体液収容器は、体液を収容するための第１収容空間を有する第１収容部と、体液を収容するための第２収容空間を有する第２収容部と、前記第１収容空間と前記第２収容空間とを分離する分離部材と、を備え、前記分離部材は、前記第１収容空間と前記第２収容空間とを連通させる開口部を封止する前方封止部と、前記前方封止部に対して前記第２収容部よりも遠い位置において前記第１収容空間を封止する後方封止部と、を有する。 The body fluid container of the present invention includes a first storage portion having a first storage space for storing body fluid, a second storage portion having a second storage space for storing body fluid, and the first storage space. The separating member includes a separating member for separating the second accommodating space, and the separating member includes a front sealing portion for sealing an opening for communicating the first accommodating space and the second accommodating space, and the front sealing portion. It has a rear sealing portion that seals the first accommodating space at a position farther than the second accommodating portion with respect to the sealing portion.

前記第１収容部は、例えば、前記第１収容空間と前記第２収容空間とを連通させる開口部を形成する中空の円錐形状の壁部を有し、前記分離部材は、前記壁部の内壁と密着する第１後方封止部を有し、前記前方封止部と前記第１後方封止部と前記壁部とに囲まれた空間に体液を収容できる。前記壁部は、例えば、前記第２収容部に近づくほど内径が小さい。 The first accommodating portion has, for example, a hollow conical wall portion forming an opening for communicating the first accommodating space and the second accommodating space, and the separating member is an inner wall of the wall portion. It has a first rear sealing portion that is in close contact with the body fluid, and can accommodate body fluid in a space surrounded by the front sealing portion, the first rear sealing portion, and the wall portion. The inner diameter of the wall portion becomes smaller as it approaches the second accommodating portion, for example.

前記第１後方封止部は円柱形状であり、前記前方封止部が前記開口部を封止した状態で、前記壁部の内壁に密着してもよい。 The first rear sealing portion has a cylindrical shape, and the front sealing portion may be in close contact with the inner wall of the wall portion in a state where the opening is sealed.

前記前方封止部は、外径が前記後方封止部の外径よりも小さい円柱形状であってもよい。また、前記前方封止部の先端部の直径は、前記開口部の内径と等しくてもよい。 The front sealing portion may have a cylindrical shape whose outer diameter is smaller than the outer diameter of the rear sealing portion. Further, the diameter of the tip portion of the front sealing portion may be equal to the inner diameter of the opening portion.

前記前方封止部は、前記開口部を封止する開口封止部と、前記後方封止部から延伸する延伸部と、前記開口封止部と前記延伸部との間に設けられており、前記開口封止部よりも細い溝部と、を有してもよい。 The front sealing portion is provided between the opening sealing portion for sealing the opening, the extending portion extending from the rear sealing portion, and the opening sealing portion and the stretched portion. It may have a groove portion thinner than the opening sealing portion.

前記分離部材は、前記体液を前記第１収容空間に入れるための開放部を封止するための第２後方封止部をさらに有してもよい。 The separating member may further have a second rear sealing portion for sealing an open portion for entering the body fluid into the first storage space.

本発明によれば、分離剤を用いることなく体液を複数の成分に分離した状態を維持できるという効果を奏する。 According to the present invention, there is an effect that the body fluid can be maintained in a state of being separated into a plurality of components without using a separating agent.

第１の実施形態の体液収容器の構成を示す図である。It is a figure which shows the structure of the body fluid container of 1st Embodiment. 第１収容部と第２収容部とが分離された状態の体液収容器の断面図である。It is sectional drawing of the body fluid container in a state where the 1st accommodating part and the 2nd accommodating part are separated. 体液採取器を収容空間に収容した状態の体液収容器の断面図である（遠心分離前）。It is sectional drawing (before centrifugation) of the body fluid container in a state where the body fluid sampler is housed in the storage space. 体液採取器を収容空間に収容した状態の体液収容器の断面図である（遠心分離後）。It is sectional drawing (after centrifugation) of the body fluid container in a state where the body fluid collector is housed in the storage space. 遠心分離後の血清を密封する方法について説明するための図である。It is a figure for demonstrating the method of sealing the serum after centrifugation. 体液収容器に収容された体液を取り出す方法について説明するための図である。It is a figure for demonstrating the method of taking out the body fluid contained in the body fluid container. 体液収容器に収容された体液を取り出す方法について説明するための図である。It is a figure for demonstrating the method of taking out the body fluid contained in the body fluid container. 第２の実施形態の体液収容器の断面図である。It is sectional drawing of the body fluid container of the 2nd Embodiment. 第１収容部に第２収容部が結合した状態の体液収容器の断面図である。It is sectional drawing of the body fluid container in the state which the 2nd accommodating part is bonded to the 1st accommodating part. 第２収容部２０を第１収容部１から取り外した状態を示す図である。It is a figure which shows the state which the 2nd accommodating part 20 was removed from the 1st accommodating part 1.

＜第１の実施形態＞
［体液収容器１００の構成］
図１は、第１の実施形態の体液収容器１００の構成を示す図である。図１（ａ）は、体液収容器１００のＡ−Ａ線断面図であり、図１（ｂ）は、体液収容器１００のＢ−Ｂ線断面図である。体液収容器１００は、体液を収容し、収容した体液を遠心分離機で遠心分離するために用いられる。以下の説明においては、体液収容器１００が血液を収容する場合について説明する。 <First Embodiment>
[Structure of body fluid container 100]
FIG. 1 is a diagram showing the configuration of the body fluid container 100 of the first embodiment. FIG. 1 (a) is a cross-sectional view taken along the line AA of the body fluid container 100, and FIG. 1 (b) is a cross-sectional view taken along the line BB of the body fluid container 100. The body fluid container 100 is used for accommodating the body fluid and centrifuging the contained body fluid with a centrifuge. In the following description, a case where the body fluid container 100 stores blood will be described.

体液収容器１００は、第１収容部１と第２収容部２とを有する。第１収容部１は、遠心分離前の体液、及び遠心分離後の体液の一部の第１成分を収容する容器である。第２収容部２は、遠心分離後の体液の一部の第２成分を収容する容器である。第１収容部１の上部には、蓋３を装着することができる。 The body fluid container 100 has a first storage unit 1 and a second storage unit 2. The first storage unit 1 is a container that stores the body fluid before centrifugation and a part of the first component of the body fluid after centrifugation. The second storage unit 2 is a container that stores a part of the second component of the body fluid after centrifugation. A lid 3 can be attached to the upper part of the first accommodating portion 1.

図２は、第１収容部１と第２収容部２とが分離された状態の体液収容器１００の断面図である。図２（ａ）は第１収容部１の断面図であり、図２（ｂ）は第２収容部２の断面図である。ユーザは、第２収容部２を第１収容部１に挿入することにより、第１収容部１と第２収容部２とを結合して、図１の状態の体液収容器１００を構成することができる。
以下、図１及び図２を参照しながら、第１収容部１及び第２収容部２の構成について説明する。 FIG. 2 is a cross-sectional view of the body fluid container 100 in a state where the first accommodating portion 1 and the second accommodating portion 2 are separated. FIG. 2A is a cross-sectional view of the first accommodating portion 1, and FIG. 2B is a cross-sectional view of the second accommodating portion 2. The user inserts the second accommodating portion 2 into the first accommodating portion 1 to combine the first accommodating portion 1 and the second accommodating portion 2 to form the body fluid container 100 in the state shown in FIG. Can be done.
Hereinafter, the configurations of the first accommodating portion 1 and the second accommodating portion 2 will be described with reference to FIGS. 1 and 2.

［第１収容部１の構成］
第１収容部１は、外壁部１１と、突起部１２と、収容壁部１３と、第１収容空間１４と、開放空間１５とを有する。
外壁部１１は、例えば円筒形状の部材であり、上方に開放部１０１を有し、下方に開放部１０２を有する。外壁部１１は、例えば、長さが約５０ｍｍであり、開放部１０１の内径が約８ｍｍであるが、外壁部１１の形状及び大きさは任意である。突起部１２は、外壁部１１の上方側の開口付近に形成された円形の突起であり、蓋３を支える部位である。 [Structure of 1st accommodating unit 1]
The first accommodating portion 1 has an outer wall portion 11, a protrusion 12, an accommodating wall portion 13, a first accommodating space 14, and an open space 15.
The outer wall portion 11 is, for example, a cylindrical member, having an opening portion 101 above and an opening portion 102 below. The outer wall portion 11 has, for example, a length of about 50 mm and an inner diameter of the open portion 101 of about 8 mm, but the shape and size of the outer wall portion 11 are arbitrary. The protrusion 12 is a circular protrusion formed near the opening on the upper side of the outer wall portion 11, and is a portion that supports the lid 3.

収容壁部１３は、外壁部１１の上方の内面から、開放部１０２に向けて延伸している中空の円錐形状の部材である。収容壁部１３は、第１収容空間１４と後述の第２収容空間２１とを連通させる開口部１０３を下方側に有する。収容壁部１３が中空の円錐形状をしているので、開口部１０３の内径は開放部１０１の内径よりも小さく、例えば２ｍｍである。 The accommodating wall portion 13 is a hollow conical member extending from the upper inner surface of the outer wall portion 11 toward the opening portion 102. The accommodating wall portion 13 has an opening 103 on the lower side for communicating the first accommodating space 14 and the second accommodating space 21 described later. Since the accommodating wall portion 13 has a hollow conical shape, the inner diameter of the opening 103 is smaller than the inner diameter of the opening 101, for example, 2 mm.

第１収容空間１４は、外壁部１１における収容壁部１３と接する位置よりも上方の内面と収容壁部１３の上方の面とによって画定される空間であり、体液を収容することができる。第１収容空間１４には、体液の採取に用いられた体液採取器（例えば体液採取器の先端チップ）を収容することもできる。 The first accommodating space 14 is a space defined by an inner surface of the outer wall portion 11 above the position in contact with the accommodating wall portion 13 and an upper surface of the accommodating wall portion 13, and can accommodate body fluids. The first storage space 14 can also accommodate a body fluid collector (for example, the tip tip of the body fluid collector) used for collecting body fluid.

開放空間１５は、外壁部１１における収容壁部１３と接する位置よりも下方の内面と収容壁部１３の下方の面とによって画定される空間である。図２に示すように、開放空間１５は、第２収容部２が結合されていない状態で外部に開放された空間である。 The open space 15 is a space defined by an inner surface below the position of the outer wall portion 11 in contact with the accommodating wall portion 13 and a surface below the accommodating wall portion 13. As shown in FIG. 2, the open space 15 is a space that is open to the outside in a state where the second accommodating portion 2 is not connected.

［第２収容部２の構成］
続いて、図１及び図２を参照しながら、第２収容部２の構成について説明する。第２収容部２は、第２収容空間２１と、円筒状の凸部２２とを有する、円柱形状の部材である。第２収容部２は、第１収容部１の下方側において第１収容部１と結合している。 [Structure of 2nd accommodating unit 2]
Subsequently, the configuration of the second accommodating portion 2 will be described with reference to FIGS. 1 and 2. The second accommodating portion 2 is a cylindrical member having a second accommodating space 21 and a cylindrical convex portion 22. The second accommodating portion 2 is connected to the first accommodating portion 1 on the lower side of the first accommodating portion 1.

第２収容空間２１は、第１収容空間１４に収容されていた体液の一部の成分を収容する凹部である。第２収容空間２１の深さは、第１収容部１に収容される体液の量によって定められる。ユーザは、それぞれ深さが異なる第２収容空間２１を有する複数の第２収容部２から、採取した体液の量に適した第２収容部２を選択して使用してもよい。 The second storage space 21 is a recess for storing a part of the body fluid contained in the first storage space 14. The depth of the second storage space 21 is determined by the amount of body fluid contained in the first storage portion 1. The user may select and use the second accommodating portion 2 suitable for the amount of the collected body fluid from the plurality of second accommodating portions 2 having the second accommodating spaces 21 having different depths.

凸部２２は、円環状の突起であり、収容壁部１３の先端部の外径よりもわずかに大きな内径を有している。凸部２２が収容壁部１３の先端に押し込まれることで、第２収容部２が収容壁部１３の先端において第１収容部１と結合する。 The convex portion 22 is an annular protrusion and has an inner diameter slightly larger than the outer diameter of the tip portion of the accommodating wall portion 13. When the convex portion 22 is pushed into the tip of the accommodating wall portion 13, the second accommodating portion 2 is coupled to the first accommodating portion 1 at the tip of the accommodating wall portion 13.

［体液を分離する方法］
図３及び図４は、体液採取器４を第１収容空間１４に収容した状態の体液収容器１００の断面図である。図３は、体液採取器４に収容された体液を遠心分離する前の状態を示しており、図４は、遠心分離した後の状態を示している。 [How to separate body fluids]
3 and 4 are cross-sectional views of the body fluid container 100 in a state where the body fluid collector 4 is housed in the first storage space 14. FIG. 3 shows a state before centrifuging the body fluid contained in the body fluid collector 4, and FIG. 4 shows a state after centrifuging.

図３及び図４を参照しながら、体液を分離する方法について説明する。図３に示す体液収容器１００の第１収容空間１４には、採取した血液ａが入った体液採取器４が挿入されている。この状態で、体液収容器１００を遠心分離機に載置して遠心分離をすることにより、図４に示すように、遠心分離中に第２収容空間２１に移動した血球ｃと、遠心分離中に第２収容空間２１に移動しなかった血清ｂとが分離された状態になる。なお、ユーザは、採取した血液ａを遠心分離した後に得られる血球ｃの容量に合った第２収容部２を使用することで、図４に示すように、血清ｂと血球ｃとの境界位置を収容壁部１３の先端に一致させることができる。 A method for separating body fluids will be described with reference to FIGS. 3 and 4. A body fluid collector 4 containing the collected blood a is inserted into the first storage space 14 of the body fluid container 100 shown in FIG. In this state, by placing the body fluid container 100 on a centrifuge and centrifuging it, as shown in FIG. 4, the blood cells c that moved to the second storage space 21 during the centrifugation are being centrifuged. The serum b that did not move to the second storage space 21 is separated from the serum b. In addition, as shown in FIG. 4, the user uses the second storage unit 2 that matches the volume of blood cells c obtained after centrifuging the collected blood a, so that the boundary position between the serum b and the blood cells c is located. Can be aligned with the tip of the accommodating wall portion 13.

［体液を密封する方法］
図５は、遠心分離後の血清ｂを密封する方法について説明するための図である。ユーザは、遠心分離後に体液採取器４を取り外して、第１収容空間１４に分離部材５を挿入することで、血清ｂと血球ｃとの間を分離することができる。分離部材５は、第１空間としての第１収容空間１４と第２収容空間２１とを分離するための部材である。 [How to seal body fluid]
FIG. 5 is a diagram for explaining a method of sealing serum b after centrifugation. The user can separate the serum b and the blood cell c by removing the body fluid collector 4 after centrifugation and inserting the separation member 5 into the first storage space 14. The separating member 5 is a member for separating the first accommodating space 14 and the second accommodating space 21 as the first space.

図５は、体液収容器１００に分離部材５が挿入された状態を示している。図５（ａ）は、体液収容器１００のＡ−Ａ断面図である。図５（ｂ）は、体液収容器１００のＣ−Ｃ断面図である。分離部材５は、前方封止部５１と、第１後方封止部５２と、第２後方封止部５３とを有する。第１後方封止部５２及び第２後方封止部５３は、前方封止部５１に対して第２収容部２よりも遠い位置において第１収容空間１４を封止する後方封止部である。 FIG. 5 shows a state in which the separating member 5 is inserted into the body fluid container 100. FIG. 5A is a cross-sectional view taken along the line AA of the body fluid container 100. FIG. 5B is a cross-sectional view taken along the line CC of the body fluid container 100. The separating member 5 has a front sealing portion 51, a first rear sealing portion 52, and a second rear sealing portion 53. The first rear sealing portion 52 and the second rear sealing portion 53 are rear sealing portions that seal the first accommodating space 14 at a position farther than the second accommodating portion 2 with respect to the front sealing portion 51. ..

前方封止部５１は、第１後方封止部５２から延伸している部分であり、収容壁部１３に囲まれた領域に挿入される。前方封止部５１は、第１後方封止部５２の外径よりも小さな外径を有する円柱形状をしている。前方封止部５１の先端部分の外径は、開口部１０３の内径と略等しく、開口部１０３の先端において開口部１０３を封止する。 The front sealing portion 51 is a portion extending from the first rear sealing portion 52, and is inserted into a region surrounded by the accommodating wall portion 13. The front sealing portion 51 has a cylindrical shape having an outer diameter smaller than the outer diameter of the first rear sealing portion 52. The outer diameter of the tip portion of the front sealing portion 51 is substantially equal to the inner diameter of the opening 103, and the opening 103 is sealed at the tip of the opening 103.

第１後方封止部５２は、前方封止部５１よりも大きな外径を有する円柱形状をしており、収容壁部１３の内壁と密着する。第１後方封止部５２は、例えば、前方封止部５１の先端が収容壁部１３の先端に達した状態で、前方封止部５１の側の底面のエッジが収容壁部１３に接触する。この状態で、前方封止部５１、第１後方封止部５２及び収容壁部１３で囲まれた空間が形成される。 The first rear sealing portion 52 has a cylindrical shape having an outer diameter larger than that of the front sealing portion 51, and is in close contact with the inner wall of the accommodating wall portion 13. In the first rear sealing portion 52, for example, when the tip of the front sealing portion 51 reaches the tip of the accommodating wall portion 13, the edge of the bottom surface on the side of the front sealing portion 51 comes into contact with the accommodating wall portion 13. .. In this state, a space surrounded by the front sealing portion 51, the first rear sealing portion 52, and the accommodating wall portion 13 is formed.

第２後方封止部５３は、第１収容部１における第２収容部２の側と反対側に形成された、体液を第１収容空間１４に入れるための開放部１０１を封止する。第２後方封止部５３は、前方封止部５１が開口部１０３を封止し、かつ第１後方封止部５２が収容壁部１３と密着した状態で、外壁部１１に嵌合して開放部１０１を封止する。 The second rear sealing portion 53 seals the opening portion 101 formed on the side of the first accommodating portion 1 opposite to the side of the second accommodating portion 2 for allowing the body fluid to enter the first accommodating space 14. The second rear sealing portion 53 is fitted to the outer wall portion 11 in a state where the front sealing portion 51 seals the opening 103 and the first rear sealing portion 52 is in close contact with the accommodating wall portion 13. The opening 101 is sealed.

前方封止部５１は、開口封止部５１１、溝部５１２、及び延伸部５１３により構成されている。開口封止部５１１は、収容壁部１３の開口部１０３側において収容壁部１３の内壁と密着することにより、第１収容空間１４を封止する。収容壁部１３は先細り形状になっているので、円柱形状の前方封止部５１が開口部１０３に向けて挿入されるにつれて、血清ｂが上方に移動する。そして、開口封止部５１１が開口部１０３を封止した状態で、開口封止部５１１と収容壁部１３と第１後方封止部５２とで囲まれた空間に血清ｂが収容された状態になる。この空間の容積が第１収容空間１４の容積よりも小さいので、血清ｂに含まれる水分等の蒸発量が少なく、血清ｂが濃縮されにくい。 The front sealing portion 51 is composed of an opening sealing portion 511, a groove portion 512, and a stretching portion 513. The opening sealing portion 511 seals the first accommodating space 14 by being in close contact with the inner wall of the accommodating wall portion 13 on the opening 103 side of the accommodating wall portion 13. Since the containment wall portion 13 has a tapered shape, the serum b moves upward as the cylindrical front sealing portion 51 is inserted toward the opening 103. Then, in a state where the opening sealing portion 511 seals the opening 103, the serum b is contained in the space surrounded by the opening sealing portion 511, the accommodating wall portion 13, and the first rear sealing portion 52. become. Since the volume of this space is smaller than the volume of the first storage space 14, the amount of evaporation of water and the like contained in the serum b is small, and the serum b is difficult to concentrate.

第２後方封止部５３が開放部１０１を封止することにより、開放部１０１から血清ｂが漏れない状態になる。したがって、この状態で体液収容器１００が傾けられても、血清ｂと血球ｃとが分離された状態が維持されるので、ユーザは、体液収容器１００を検査センターに輸送することができる。 When the second rear sealing portion 53 seals the opening portion 101, the serum b does not leak from the opening portion 101. Therefore, even if the body fluid container 100 is tilted in this state, the state in which the serum b and the blood cells c are separated is maintained, so that the user can transport the body fluid container 100 to the examination center.

溝部５１２は、開口封止部５１１と延伸部５１３との間に円環状に形成されている部分である。溝部５１２の位置において、前方封止部５１は、開口封止部５１１及び延伸部５１３よりも細くなっている。 The groove portion 512 is a portion formed in an annular shape between the opening sealing portion 511 and the extending portion 513. At the position of the groove portion 512, the front sealing portion 51 is thinner than the opening sealing portion 511 and the extending portion 513.

延伸部５１３は、第１後方封止部５２から第２収容部２に向けて延伸している円柱形状の部分である。延伸部５１３の直径は、溝部５１２の直径よりも大きく、かつ第１後方封止部５２の直径よりも小さい範囲であれば、任意の大きさであってもよい。延伸部５１３の直径は、例えば、開口封止部５１１の直径と同一である。 The stretched portion 513 is a cylindrical portion extending from the first rear sealing portion 52 toward the second accommodating portion 2. The diameter of the stretched portion 513 may be any size as long as it is larger than the diameter of the groove portion 512 and smaller than the diameter of the first rear sealing portion 52. The diameter of the stretched portion 513 is, for example, the same as the diameter of the opening sealing portion 511.

［体液を取り出す方法］
図６及び図７は、体液収容器１００に収容された体液を取り出す方法について説明するための図である。図５に示したように、溝部５１２の位置において、前方封止部５１は、開口封止部５１１及び延伸部５１３よりも細くなっている。したがって、開口封止部５１１が収容壁部１３の先端の位置で収容壁部１３の内壁に密着している状態でユーザが分離部材５を回転させる力を加えた場合、開口封止部５１１は回転せず、溝部５１２よりも上に位置する延伸部５１３及び第２後方封止部５３だけが回転する。その結果、図６に示すように、分離部材５は、溝部５１２の位置で切断される。 [How to take out body fluid]
6 and 7 are diagrams for explaining a method of taking out the body fluid contained in the body fluid container 100. As shown in FIG. 5, at the position of the groove portion 512, the front sealing portion 51 is thinner than the opening sealing portion 511 and the extending portion 513. Therefore, when the user applies a force to rotate the separation member 5 while the opening sealing portion 511 is in close contact with the inner wall of the accommodating wall portion 13 at the position of the tip of the accommodating wall portion 13, the opening sealing portion 511 It does not rotate, and only the extension portion 513 and the second rear sealing portion 53 located above the groove portion 512 rotate. As a result, as shown in FIG. 6, the separating member 5 is cut at the position of the groove portion 512.

図６は、分離部材５が溝部５１２の位置で切断されて、開口封止部５１１と延伸部５１３及び第２後方封止部５３とが分離した状態を示している。開口封止部５１１は、収容壁部１３の先端付近の開口部１０３を封止した状態で残り、ユーザは、延伸部５１３、第１後方封止部５２及び第２後方封止部５３を含む分離部材５を取り出すことができる。 FIG. 6 shows a state in which the separating member 5 is cut at the position of the groove portion 512, and the opening sealing portion 511, the extending portion 513, and the second rear sealing portion 53 are separated. The opening sealing portion 511 remains in a state of sealing the opening 103 near the tip of the accommodating wall portion 13, and the user includes the extending portion 513, the first rear sealing portion 52, and the second rear sealing portion 53. The separating member 5 can be taken out.

図７は、分離部材５が取り出されるとともに、血清ｂが収容された第１収容部１を第２収容部２から分離した状態を示す図である。この状態で、ユーザは、開放部１０１から血清ｂを取り出すことができる。 FIG. 7 is a diagram showing a state in which the separation member 5 is taken out and the first storage portion 1 in which the serum b is stored is separated from the second storage portion 2. In this state, the user can take out the serum b from the opening 101.

［体液収容器１００による効果］
以上説明したように、体液収容器１００は、第１収容部１が有する第１収容空間１４と、第２収容部２が有する第２収容空間２１とを連通させる開口部１０３を形成する中空の円錐形状の収容壁部１３を有する。そして、開口部１０３を封止する前方封止部５１と、前方封止部５１が開口部１０３を封止した状態で収容壁部１３の内壁に密着する第１後方封止部５２とを有する。このようにすることで、体液収容器１００は、分離剤を用いることなく、前方封止部５１、第１後方封止部５２及び収容壁部１３により囲まれた空間に収容された血清ｂと、第２収容部２に収容された血球ｃとを分離した状態を維持することができる。 [Effect of body fluid container 100]
As described above, the body fluid container 100 is a hollow hollow portion forming an opening 103 that communicates the first storage space 14 of the first storage unit 1 and the second storage space 21 of the second storage unit 2. It has a conical housing wall portion 13. Then, it has a front sealing portion 51 that seals the opening 103, and a first rear sealing portion 52 that is in close contact with the inner wall of the accommodating wall portion 13 in a state where the front sealing portion 51 seals the opening 103. .. By doing so, the body fluid container 100 can be combined with the serum b contained in the space surrounded by the front sealing portion 51, the first rear sealing portion 52, and the containing wall portion 13 without using a separating agent. , The state in which the blood cells c housed in the second storage unit 2 are separated can be maintained.

また、前方封止部５１が開口部１０３を封止し、かつ第１後方封止部５２が収容壁部１３の内壁と密着した状態で、第２後方封止部５３により開放部１０１が封止される。したがって、体液収容器１００が傾いても血清ｂと血球ｃとが分離された状態が維持されるので、ユーザは、体液収容器１００を検査センターに輸送することができる。 Further, with the front sealing portion 51 sealing the opening 103 and the first rear sealing portion 52 in close contact with the inner wall of the accommodating wall portion 13, the opening portion 101 is sealed by the second rear sealing portion 53. It will be stopped. Therefore, even if the body fluid container 100 is tilted, the state in which the serum b and the blood cells c are separated is maintained, so that the user can transport the body fluid container 100 to the examination center.

（変形例）
第１の実施形態の体液収容器１００においては、分離部材５が第１後方封止部５２を有し、第１後方封止部５２が収容壁部１３の内壁に密着することにより、血清ｂを密封できる空間が形成されていた。これに対して、第１後方封止部５２が収容壁部１３の内壁に接していなかったり、分離部材５が第１後方封止部５２を有していなかったりしてもよい。 (Modification example)
In the body fluid container 100 of the first embodiment, the separating member 5 has the first rear sealing portion 52, and the first rear sealing portion 52 is in close contact with the inner wall of the accommodating wall portion 13, whereby the serum b A space was formed that could be sealed. On the other hand, the first rear sealing portion 52 may not be in contact with the inner wall of the accommodating wall portion 13, or the separating member 5 may not have the first rear sealing portion 52.

この場合、開口封止部５１１が開口部１０３を封止した状態で、第２後方封止部５３が開放部１０１を封止することにより形成される、開口封止部５１１、第２後方封止部５３、収容壁部１３、及び外壁部１１で囲まれた第１収容空間１４に血清ｂが密封される。このような構成であっても、体液収容器１００が傾いても血清ｂと血球ｃとが分離された状態が維持されるので、ユーザは、血清ｂと血球ｃとが分離された状態で体液収容器１００を検査センターに輸送することができる。 In this case, the opening sealing portion 511 and the second rear sealing portion 511 are formed by the second rear sealing portion 53 sealing the opening portion 101 while the opening sealing portion 511 seals the opening 103. Serum b is sealed in the first storage space 14 surrounded by the stop portion 53, the storage wall portion 13, and the outer wall portion 11. Even with such a configuration, the state in which the serum b and the blood cells c are separated is maintained even if the body fluid container 100 is tilted, so that the user can use the body fluid in a state in which the serum b and the blood cells c are separated. The container 100 can be transported to the inspection center.

＜第２の実施形態＞
図８は、第２の実施形態の体液収容器２００の断面図である。体液収容器２００は、第２収容部２に代えて第２収容部２０を有する点で、第１の実施形態の体液収容器１００と異なり、他の点で同じである。第２収容部２０は、第２収容空間２３と、円筒状の凸部２４とを有する。 <Second embodiment>
FIG. 8 is a cross-sectional view of the body fluid container 200 of the second embodiment. The body fluid container 200 is different from the body fluid container 100 of the first embodiment in that it has a second storage unit 20 instead of the second storage unit 2, and is the same in other respects. The second accommodating portion 20 has a second accommodating space 23 and a cylindrical convex portion 24.

凸部２４は、第２収容部２の凸部２２よりも長く延伸しており、第２収容空間２３の容積は、第２収容部２の第２収容空間２１の容積よりも大きい。凸部２４の外径は、第１収容部１の外壁部１１の内径と略同じであり、凸部２４は、外壁部１１の内側に嵌合する。 The convex portion 24 extends longer than the convex portion 22 of the second accommodating portion 2, and the volume of the second accommodating space 23 is larger than the volume of the second accommodating space 21 of the second accommodating portion 2. The outer diameter of the convex portion 24 is substantially the same as the inner diameter of the outer wall portion 11 of the first accommodating portion 1, and the convex portion 24 fits inside the outer wall portion 11.

図９は、第１収容部１に第２収容部２０が結合した状態の体液収容器２００の断面図である。第２収容部２０の第２収容空間２３には、遠心分離後の血球ｃが収容されている。 FIG. 9 is a cross-sectional view of the body fluid container 200 in a state where the second storage unit 20 is coupled to the first storage unit 1. Blood cells c after centrifugation are housed in the second storage space 23 of the second storage unit 20.

図１０は、図９の状態の体液収容器２００において、第２収容部２０を第１収容部１から取り外した状態を示す図である。第２収容部２０の第２収容空間２３には溶血剤が添加され、溶血剤と血球ｃとが混合した混合液ｄが収容されている。 FIG. 10 is a diagram showing a state in which the second storage unit 20 is removed from the first storage unit 1 in the body fluid container 200 in the state of FIG. A hemolytic agent is added to the second accommodating space 23 of the second accommodating portion 20, and a mixed solution d in which the hemolytic agent and the blood cells c are mixed is accommodated.

第１の実施形態の第２収容部２のように血球ｃを収容できる空間の容積が小さい場合、血球ｃを検査（例えばＨｂＡｃ１検査）する際には、第２収容部２からピペットで血球ｃを吸い取って、溶血剤と混合するための別の容器に移す必要があった。これに対して、第２の実施形態の第２収容部２０のように血球ｃを収容できる空間の容積が大きい場合には、血球ｃを別の容器に移すことなく、第２収容部２０にそのまま溶血剤を添加することができる。したがって、体液収容器２００を用いることにより、検査効率が大幅に向上する。 When the volume of the space capable of accommodating the blood cells c is small as in the second accommodating portion 2 of the first embodiment, when inspecting the blood cells c (for example, HbAc1 inspection), the blood cells c are pipetteed from the second accommodating portion 2. Needed to be sucked up and transferred to another container for mixing with the hemolytic agent. On the other hand, when the volume of the space capable of accommodating the blood cells c is large as in the second accommodating portion 20 of the second embodiment, the blood cells c are moved to the second accommodating portion 20 without being transferred to another container. The hemolytic agent can be added as it is. Therefore, by using the body fluid container 200, the inspection efficiency is greatly improved.

以上、本発明を実施の形態を用いて説明したが、本発明の技術的範囲は上記実施の形態に記載の範囲には限定されず、その要旨の範囲内で種々の変形及び変更が可能である。例えば、装置の分散・統合の具体的な実施の形態は、以上の実施の形態に限られず、その全部又は一部について、任意の単位で機能的又は物理的に分散・統合して構成することができる。また、複数の実施の形態の任意の組み合わせによって生じる新たな実施の形態も、本発明の実施の形態に含まれる。組み合わせによって生じる新たな実施の形態の効果は、もとの実施の形態の効果を合わせ持つ。 Although the present invention has been described above using the embodiments, the technical scope of the present invention is not limited to the scope described in the above embodiments, and various modifications and changes can be made within the scope of the gist thereof. is there. For example, the specific embodiment of the distribution / integration of the device is not limited to the above embodiment, and all or a part thereof may be functionally or physically distributed / integrated in any unit. Can be done. Also included in the embodiments of the present invention are new embodiments resulting from any combination of the plurality of embodiments. The effect of the new embodiment produced by the combination has the effect of the original embodiment together.

１ 第１収容部
２ 第２収容部
３ 蓋
４ 体液採取器
５ 分離部材
１１ 外壁部
１２ 突起部
１３ 収容壁部
１４ 第１収容空間
１５ 開放空間
２０ 第２収容部
２１ 第２収容空間
２２ 凸部
２３ 第２収容空間
２４ 凸部
５１ 前方封止部
５２ 第１後方封止部
５３ 第２後方封止部
１００ 体液収容器
１０１ 開放部
１０２ 開放部
１０３ 開口部
５１１ 開口封止部
５１２ 溝部
５１３ 延伸部 1 1st accommodating part 2 2nd accommodating part 3 Lid 4 Body fluid sampler 5 Separation member 11 Outer wall part 12 Projection part 13 Accommodating wall part 14 1st accommodating space 15 Open space 20 2nd accommodating part 21 2nd accommodating space 22 Convex part 23 Second accommodating space 24 Convex part 51 Front sealing part 52 First rear sealing part 53 Second rear sealing part 100 Body fluid container 101 Opening part 102 Opening part 103 Opening part 511 Opening sealing part 512 Groove part 513 Extension part

Claims (8)

体液を収容するための第１収容空間を有する第１収容部と、
体液を収容するための第２収容空間を有する第２収容部と、
前記第１収容空間と前記第２収容空間とを分離する分離部材と、
を備え、
前記分離部材は、
前記第１収容空間と前記第２収容空間とを連通させる開口部を封止する前方封止部と、
前記前方封止部に対して前記第２収容部よりも遠い位置において前記第１収容空間を封止する後方封止部と、
を有し、
前記第１収容部は、前記第１収容空間と前記第２収容空間とを連通させる開口部を形成する中空の円錐形状の壁部を有し、
前記第２収容部は、前記第１収容部における前記開口部の内径よりも大きな内径の円筒状の凸部を有することを特徴とする体液収容器。 A first containment unit having a first containment space for accommodating body fluids,
A second accommodating section having a second accommodating space for accommodating body fluids,
A separating member that separates the first accommodating space and the second accommodating space,
With
The separating member
A front sealing portion that seals an opening that communicates the first accommodating space and the second accommodating space, and a front sealing portion.
A rear sealing portion that seals the first accommodating space at a position farther than the second accommodating portion with respect to the front sealing portion, and a rear sealing portion.
Have a,
The first accommodating portion has a hollow conical wall portion forming an opening for communicating the first accommodating space and the second accommodating space.
The body fluid container is characterized in that the second accommodating portion has a cylindrical convex portion having an inner diameter larger than the inner diameter of the opening in the first accommodating portion. 前記前方封止部は、外径が前記後方封止部の外径よりも小さい円柱形状であることを特徴とする、
請求項１に記載の体液収容器。 The front sealing portion has a cylindrical shape having an outer diameter smaller than the outer diameter of the rear sealing portion.
The body fluid container according to claim 1. 前記前方封止部の先端部の直径は、前記開口部の内径と等しいことを特徴とする、
請求項１又は２に記載の体液収容器。 The diameter of the tip of the front sealing portion is equal to the inner diameter of the opening.
The body fluid container according to claim 1 or 2. 前記分離部材は、前記体液を前記第１収容空間に入れるための開放部を封止するための第２後方封止部をさらに有することを特徴とする、
請求項１から３のいずれか一項に記載の体液収容器。 The separating member further includes a second rear sealing portion for sealing an opening portion for entering the body fluid into the first storage space.
The body fluid container according to any one of claims 1 to 3. 体液を収容するための第１収容空間を有する第１収容部と、
体液を収容するための第２収容空間を有する第２収容部と、
前記第１収容空間と前記第２収容空間とを分離する分離部材と、
を備え、
前記分離部材は、
前記第１収容空間と前記第２収容空間とを連通させる開口部を封止する前方封止部と、
前記前方封止部に対して前記第２収容部よりも遠い位置において前記第１収容空間を封止する後方封止部と、
を有し、
前記第１収容部は、前記第１収容空間と前記第２収容空間とを連通させる開口部を形成する中空の円錐形状の壁部を有し、
前記分離部材は、前記壁部の内壁と密着する第１後方封止部を有し、
前記前方封止部と前記第１後方封止部と前記壁部とに囲まれた空間に体液を収容できることを特徴とする体液収容器。 A first containment unit having a first containment space for accommodating body fluids,
A second accommodating section having a second accommodating space for accommodating body fluids,
A separating member that separates the first accommodating space and the second accommodating space,
With
The separating member
A front sealing portion that seals an opening that communicates the first accommodating space and the second accommodating space, and a front sealing portion.
A rear sealing portion that seals the first accommodating space at a position farther than the second accommodating portion with respect to the front sealing portion, and a rear sealing portion.
Have,
The first accommodating portion has a hollow conical wall portion forming an opening for communicating the first accommodating space and the second accommodating space.
The separating member has a first rear sealing portion that is in close contact with the inner wall of the wall portion.
A body fluid container capable of accommodating a body fluid in a space surrounded by the front sealing portion, the first rear sealing portion, and the wall portion . 前記壁部は、前記第２収容部に近づくほど内径が小さいことを特徴とする、
請求項５に記載の体液収容器。 The wall portion has a smaller inner diameter as it approaches the second accommodating portion.
The body fluid container according to claim 5. 前記第１後方封止部は円柱形状であり、前記前方封止部が前記開口部を封止した状態で、前記壁部の内壁に密着することを特徴とする、
請求項５又は６に記載の体液収容器。 The first rear sealing portion has a cylindrical shape, and the front sealing portion seals the opening and is in close contact with the inner wall of the wall portion.
The body fluid container according to claim 5 or 6. 体液を収容するための第１収容空間を有する第１収容部と、
体液を収容するための第２収容空間を有する第２収容部と、
前記第１収容空間と前記第２収容空間とを分離する分離部材と、
を備え、
前記分離部材は、
前記第１収容空間と前記第２収容空間とを連通させる開口部を封止する前方封止部と、
前記前方封止部に対して前記第２収容部よりも遠い位置において前記第１収容空間を封止する後方封止部と、
を有し、
前記前方封止部は、
前記開口部を封止する開口封止部と、
前記後方封止部から延伸する延伸部と、
前記開口封止部と前記延伸部との間に設けられており、前記開口封止部よりも細い溝部と、
を有することを特徴とする、
体液収容器。 A first containment unit having a first containment space for accommodating body fluids,
A second accommodating section having a second accommodating space for accommodating body fluids,
A separating member that separates the first accommodating space and the second accommodating space,
With
The separating member
A front sealing portion that seals an opening that communicates the first accommodating space and the second accommodating space, and a front sealing portion.
A rear sealing portion that seals the first accommodating space at a position farther than the second accommodating portion with respect to the front sealing portion, and a rear sealing portion.
Have,
The front sealing portion is
An opening sealing portion that seals the opening, and an opening sealing portion.
A stretched portion extending from the rear sealing portion and a stretched portion
A groove portion provided between the opening sealing portion and the extending portion and narrower than the opening sealing portion, and a groove portion
Characterized by having
Body fluid container.
JP2017057370A 2017-03-23 2017-03-23 Body fluid container Active JP6836433B2 (en)

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Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101194044B1 (en) * 2011-12-29 2012-10-24 (주) 알메디카 Single unit kit for separating blood and concentrating prp and method for extracting prp using thereof
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