JP2015526435A - 抗体成分と血液脳関門を通過するポリペプチドと細胞毒とを含むコンジュゲート - Google Patents

抗体成分と血液脳関門を通過するポリペプチドと細胞毒とを含むコンジュゲート Download PDF

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JP2015526435A
JP2015526435A JP2015526846A JP2015526846A JP2015526435A JP 2015526435 A JP2015526435 A JP 2015526435A JP 2015526846 A JP2015526846 A JP 2015526846A JP 2015526846 A JP2015526846 A JP 2015526846A JP 2015526435 A JP2015526435 A JP 2015526435A
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polypeptide
conjugate
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antibody
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カステーニュ，ジャン−ポール
ヤン，ガオチアン
シュ，クリスチャン
デミュール，ミシェル
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アンジオケム インコーポレーテッド
アンジオケム インコーポレーテッド
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    • C—CHEMISTRY; METALLURGY
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    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

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JP2015526846A 2012-08-14 2013-08-14 抗体成分と血液脳関門を通過するポリペプチドと細胞毒とを含むコンジュゲート Pending JP2015526435A (ja)

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US201261682991P 2012-08-14 2012-08-14
US61/682,991 2012-08-14
US201361865071P 2013-08-12 2013-08-12
US61/865,071 2013-08-12
PCT/CA2013/050625 WO2014026286A1 (en) 2012-08-14 2013-08-14 Conjugates including an antibody moiety, a polypeptide that traverses the blood-brain barrier, and a cytotoxin

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JP2015526435A true JP2015526435A (ja) 2015-09-10
JP2015526435A5 JP2015526435A5 (enExample) 2016-03-31

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US (2) US20160106856A1 (enExample)
EP (1) EP2885321A4 (enExample)
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CN (1) CN104781281A (enExample)
AU (1) AU2013302273A1 (enExample)
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WO2007009229A1 (en) 2005-07-15 2007-01-25 Angiochem Inc. Use of aprotinin polypeptides as carriers in pharmaceutical conjugates
WO2010043047A1 (en) 2008-10-15 2010-04-22 Angiochem Inc. Conjugates of glp-1 agonists and uses thereof
US9914754B2 (en) 2008-12-05 2018-03-13 Angiochem Inc. Conjugates of neurotensin or neurotensin analogs and uses thereof
JP2015526434A (ja) 2012-08-14 2015-09-10 アンジオケム インコーポレーテッド ペプチド−デンドリマーコンジュゲート及びその使用
UA120364C2 (uk) 2014-04-25 2019-11-25 Пьєр Фабр Медікамент Кон'югат антитіла до igf-1r з лікарським засобом
PL3134125T3 (pl) 2014-04-25 2020-04-30 Pierre Fabre Médicament Koniugat przeciwciało-lek i jego zastosowanie do leczenia raka
US20170326233A1 (en) * 2014-11-14 2017-11-16 Angiochem Inc. Conjugates including an antibody moiety, a polypeptide that traverses the blood-brain barrier, and a cytotoxin
EP3307326B9 (en) 2015-06-15 2021-02-24 Angiochem Inc. Methods for the treatment of leptomeningeal carcinomatosis
WO2019190293A1 (ko) * 2018-03-30 2019-10-03 한미약품 주식회사 뇌 표적 지속성 단백질 결합체, 이의 제조 방법, 및 이를 포함하는 조성물
WO2020069488A1 (en) * 2018-09-28 2020-04-02 North Carolina State University Compositions and methods for drug delivery
CA3149263A1 (en) * 2019-08-28 2021-03-04 David Owen Targeted dendrimer conjugates
US20240293588A1 (en) * 2020-06-03 2024-09-05 Starpharma Pty Ltd Therapeutic conjugates
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