JP2015521611A5 - - Google Patents

Info

Publication number

JP2015521611A5

JP2015521611A5 JP2015517753A JP2015517753A JP2015521611A5 JP 2015521611 A5 JP2015521611 A5 JP 2015521611A5 JP 2015517753 A JP2015517753 A JP 2015517753A JP 2015517753 A JP2015517753 A JP 2015517753A JP 2015521611 A5 JP2015521611 A5 JP 2015521611A5

Authority

JP

Japan

Prior art keywords

peptide

peptide according

seq

disease

acid sequence

Prior art date

2013-06-19

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Granted

Links

• Espacenet
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• 108090000765 processed proteins & peptides Proteins 0.000 claims 17
• 102100024616 Platelet endothelial cell adhesion molecule Human genes 0.000 claims 5
• 125000003275 alpha amino acid group Chemical group 0.000 claims 4
• 150000001413 amino acids Chemical class 0.000 claims 4
• 239000007787 solid Substances 0.000 claims 3
• 208000022559 Inflammatory bowel disease Diseases 0.000 claims 2
• 208000007536 Thrombosis Diseases 0.000 claims 2
• 201000010099 disease Diseases 0.000 claims 2
• 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 2
• 208000027866 inflammatory disease Diseases 0.000 claims 2
• FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
• 208000004476 Acute Coronary Syndrome Diseases 0.000 claims 1
• 206010003178 Arterial thrombosis Diseases 0.000 claims 1
• 201000001320 Atherosclerosis Diseases 0.000 claims 1
• 208000023328 Basedow disease Diseases 0.000 claims 1
• 241000283690 Bos taurus Species 0.000 claims 1
• 208000005145 Cerebral amyloid angiopathy Diseases 0.000 claims 1
• 206010012438 Dermatitis atopic Diseases 0.000 claims 1
• 208000015023 Graves' disease Diseases 0.000 claims 1
• 208000032382 Ischaemic stroke Diseases 0.000 claims 1
• 208000005764 Peripheral Arterial Disease Diseases 0.000 claims 1
• 208000030831 Peripheral arterial occlusive disease Diseases 0.000 claims 1
• 201000004681 Psoriasis Diseases 0.000 claims 1
• 210000001744 T-lymphocyte Anatomy 0.000 claims 1
• 206010047115 Vasculitis Diseases 0.000 claims 1
• 208000002223 abdominal aortic aneurysm Diseases 0.000 claims 1
• 230000004913 activation Effects 0.000 claims 1
• 208000007474 aortic aneurysm Diseases 0.000 claims 1
• 230000007214 atherothrombosis Effects 0.000 claims 1
• 201000008937 atopic dermatitis Diseases 0.000 claims 1
• 206010012601 diabetes mellitus Diseases 0.000 claims 1
• 239000012634 fragment Substances 0.000 claims 1
• 238000001727 in vivo Methods 0.000 claims 1
• 230000001404 mediated effect Effects 0.000 claims 1
• 201000006417 multiple sclerosis Diseases 0.000 claims 1
• 210000005259 peripheral blood Anatomy 0.000 claims 1
• 239000011886 peripheral blood Substances 0.000 claims 1
• 239000008194 pharmaceutical composition Substances 0.000 claims 1
• 230000036470 plasma concentration Effects 0.000 claims 1
• 102000004196 processed proteins & peptides Human genes 0.000 claims 1
• 206010039073 rheumatoid arthritis Diseases 0.000 claims 1
• 230000011664 signaling Effects 0.000 claims 1
• 238000007920 subcutaneous administration Methods 0.000 claims 1
• 239000013589 supplement Substances 0.000 claims 1
• 201000000596 systemic lupus erythematosus Diseases 0.000 claims 1