JP2015521475A5 - - Google Patents
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- Publication number
- JP2015521475A5 JP2015521475A5 JP2015517669A JP2015517669A JP2015521475A5 JP 2015521475 A5 JP2015521475 A5 JP 2015521475A5 JP 2015517669 A JP2015517669 A JP 2015517669A JP 2015517669 A JP2015517669 A JP 2015517669A JP 2015521475 A5 JP2015521475 A5 JP 2015521475A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- bag3
- nucleotide
- biological sample
- kit according
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002773 nucleotide Substances 0.000 claims 9
- 125000003729 nucleotide group Chemical group 0.000 claims 9
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 8
- 239000012472 biological sample Substances 0.000 claims 7
- 208000019622 heart disease Diseases 0.000 claims 6
- 238000000034 method Methods 0.000 claims 6
- 108091032973 (ribonucleotides)n+m Proteins 0.000 claims 5
- 102100027954 BAG family molecular chaperone regulator 3 Human genes 0.000 claims 5
- 101000697871 Homo sapiens BAG family molecular chaperone regulator 3 Proteins 0.000 claims 5
- 206010028980 Neoplasm Diseases 0.000 claims 4
- 201000011510 cancer Diseases 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 4
- 230000002757 inflammatory effect Effects 0.000 claims 4
- 230000001575 pathological effect Effects 0.000 claims 4
- 239000013615 primer Substances 0.000 claims 4
- 239000012634 fragment Substances 0.000 claims 3
- 210000002381 plasma Anatomy 0.000 claims 3
- 210000003296 saliva Anatomy 0.000 claims 3
- 210000002966 serum Anatomy 0.000 claims 3
- 210000001519 tissue Anatomy 0.000 claims 3
- 210000002700 urine Anatomy 0.000 claims 3
- 206010002383 Angina Pectoris Diseases 0.000 claims 2
- 206010005003 Bladder cancer Diseases 0.000 claims 2
- 206010007556 Cardiac failure acute Diseases 0.000 claims 2
- 206010007558 Cardiac failure chronic Diseases 0.000 claims 2
- 206010057254 Connective tissue inflammation Diseases 0.000 claims 2
- 206010019280 Heart failures Diseases 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- 241000124008 Mammalia Species 0.000 claims 2
- 206010061902 Pancreatic neoplasm Diseases 0.000 claims 2
- 206010060862 Prostate cancer Diseases 0.000 claims 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 claims 2
- 238000011529 RT qPCR Methods 0.000 claims 2
- 208000007814 Unstable Angina Diseases 0.000 claims 2
- 208000007097 Urinary Bladder Neoplasms Diseases 0.000 claims 2
- 230000001154 acute effect Effects 0.000 claims 2
- 210000004204 blood vessel Anatomy 0.000 claims 2
- 210000000988 bone and bone Anatomy 0.000 claims 2
- 208000029078 coronary artery disease Diseases 0.000 claims 2
- 238000001514 detection method Methods 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 230000000642 iatrogenic effect Effects 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 201000004332 intermediate coronary syndrome Diseases 0.000 claims 2
- 208000028867 ischemia Diseases 0.000 claims 2
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 claims 2
- 208000010125 myocardial infarction Diseases 0.000 claims 2
- 210000005036 nerve Anatomy 0.000 claims 2
- 201000002528 pancreatic cancer Diseases 0.000 claims 2
- 208000008443 pancreatic carcinoma Diseases 0.000 claims 2
- 238000011002 quantification Methods 0.000 claims 2
- 239000000523 sample Substances 0.000 claims 2
- 210000003491 skin Anatomy 0.000 claims 2
- 201000005112 urinary bladder cancer Diseases 0.000 claims 2
- FWMNVWWHGCHHJJ-SKKKGAJSSA-N 4-amino-1-[(2r)-6-amino-2-[[(2r)-2-[[(2r)-2-[[(2r)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanoyl]amino]hexanoyl]piperidine-4-carboxylic acid Chemical compound C([C@H](C(=O)N[C@H](CC(C)C)C(=O)N[C@H](CCCCN)C(=O)N1CCC(N)(CC1)C(O)=O)NC(=O)[C@H](N)CC=1C=CC=CC=1)C1=CC=CC=C1 FWMNVWWHGCHHJJ-SKKKGAJSSA-N 0.000 claims 1
- 101150039216 Bag3 gene Proteins 0.000 claims 1
- 239000003155 DNA primer Substances 0.000 claims 1
- 238000000137 annealing Methods 0.000 claims 1
- 238000003745 diagnosis Methods 0.000 claims 1
- 230000014509 gene expression Effects 0.000 claims 1
- 238000000338 in vitro Methods 0.000 claims 1
- 238000001727 in vivo Methods 0.000 claims 1
- 108020004999 messenger RNA Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12172531.1 | 2012-06-19 | ||
| EP12172531.1A EP2676966A1 (en) | 2012-06-19 | 2012-06-19 | BAG3 as biochemical serum and tissue marker |
| PCT/EP2013/061971 WO2013189775A1 (en) | 2012-06-19 | 2013-06-11 | Bag3 as biochemical serum and tissue marker |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015521475A JP2015521475A (ja) | 2015-07-30 |
| JP2015521475A5 true JP2015521475A5 (enExample) | 2016-07-28 |
Family
ID=48607259
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015517669A Pending JP2015521475A (ja) | 2012-06-19 | 2013-06-11 | 生化学的血清マーカーおよび組織マーカーとしてのｂａｇ３ |
| JP2015517672A Expired - Fee Related JP6654432B2 (ja) | 2012-06-19 | 2013-06-11 | 生化学的血清マーカーおよび組織マーカーとしてのｂａｇ３ |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015517672A Expired - Fee Related JP6654432B2 (ja) | 2012-06-19 | 2013-06-11 | 生化学的血清マーカーおよび組織マーカーとしてのｂａｇ３ |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US10359433B2 (enExample) |
| EP (3) | EP2676966A1 (enExample) |
| JP (2) | JP2015521475A (enExample) |
| KR (2) | KR102150903B1 (enExample) |
| CN (2) | CN104507965B (enExample) |
| AU (2) | AU2013279604B2 (enExample) |
| BR (2) | BR112014031957A2 (enExample) |
| CA (2) | CA2876922C (enExample) |
| ES (1) | ES2795981T3 (enExample) |
| IN (2) | IN2014DN10562A (enExample) |
| PL (1) | PL2861618T3 (enExample) |
| WO (2) | WO2013189778A1 (enExample) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ITMI20130403A1 (it) | 2013-03-18 | 2014-09-19 | Biouniversa Srl | Anticorpi anti-bag3 per uso terapeutico |
| CN105021825B (zh) * | 2015-07-09 | 2016-08-17 | 陈勇 | 一种检测胰腺癌相关多肽dap44的elisa试剂盒 |
| CN105769900A (zh) * | 2016-03-22 | 2016-07-20 | 山西大学 | Bag3基因在制备抗膀胱癌药物中的应用 |
| IT201600069391A1 (it) * | 2016-07-04 | 2016-10-04 | Univ Degli Studi Di Salerno | Uso della proteina bag3 e suoi frammenti peptidici per il controllo dell’omeostasi vascolare |
| WO2021140173A1 (en) | 2020-01-10 | 2021-07-15 | Biouniversa S.R.L. | Methods and uses for treating fibrotic solid tumors with bags inhibitors |
| US11940450B2 (en) | 2021-03-16 | 2024-03-26 | University Of Connecticut | Biomarker panel for non-invasive diagnosis of congenital renal dysfunction |
| CN113862361B (zh) * | 2021-10-25 | 2023-08-15 | 中山大学孙逸仙纪念医院 | 一种诊断和治疗膀胱癌的分子标志物hsf1及其用途 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5652223A (en) * | 1994-03-14 | 1997-07-29 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | DNA encoding CAI resistance proteins and uses thereof |
| CA2379264A1 (en) * | 1999-07-09 | 2001-01-18 | The Burnham Institute | A method for determining the prognosis of cancer patients by measuring levels of bag expression |
| US20030073623A1 (en) * | 2001-07-30 | 2003-04-17 | Drmanac Radoje T. | Novel nucleic acid sequences obtained from various cDNA libraries |
| JP4424987B2 (ja) * | 2001-09-20 | 2010-03-03 | ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム | Ｅｌｉｓａアッセイを用いた循環する治療抗体、抗原および抗原／抗体複合体の測定 |
| EP1323733A1 (en) * | 2001-12-28 | 2003-07-02 | Arturo Leone | BAG3 nucleotide and protein sequences to be used in research, diagnostics and therapy for cell death-involving diseases |
| US20090047689A1 (en) * | 2007-06-20 | 2009-02-19 | John Kolman | Autoantigen biomarkers for early diagnosis of lung adenocarcinoma |
| WO2011044927A1 (en) * | 2009-10-12 | 2011-04-21 | INSERM (Institut National de la Santé et de la Recherche Médicale) | A method for the diagnosis or prognosis of an advanced heart failure |
| IT1397083B1 (it) * | 2009-12-04 | 2012-12-28 | Biouniversa Srl | Marcatore biochimico serico |
| GB201017520D0 (en) * | 2010-10-15 | 2010-12-01 | Sense Proteomic Ltd | Biomarkers |
-
2012
- 2012-06-19 EP EP12172531.1A patent/EP2676966A1/en not_active Withdrawn
-
2013
- 2013-06-11 PL PL13728180T patent/PL2861618T3/pl unknown
- 2013-06-11 KR KR1020157001313A patent/KR102150903B1/ko not_active Expired - Fee Related
- 2013-06-11 BR BR112014031957A patent/BR112014031957A2/pt not_active IP Right Cessation
- 2013-06-11 WO PCT/EP2013/061976 patent/WO2013189778A1/en not_active Ceased
- 2013-06-11 CN CN201380032138.3A patent/CN104507965B/zh not_active Expired - Fee Related
- 2013-06-11 JP JP2015517669A patent/JP2015521475A/ja active Pending
- 2013-06-11 EP EP13728180.4A patent/EP2861618B1/en active Active
- 2013-06-11 CN CN201380032196.6A patent/CN104619861A/zh active Pending
- 2013-06-11 EP EP13728375.0A patent/EP2861754A1/en not_active Ceased
- 2013-06-11 CA CA2876922A patent/CA2876922C/en active Active
- 2013-06-11 KR KR20157001228A patent/KR20150036102A/ko not_active Withdrawn
- 2013-06-11 CA CA2876872A patent/CA2876872A1/en not_active Abandoned
- 2013-06-11 WO PCT/EP2013/061971 patent/WO2013189775A1/en not_active Ceased
- 2013-06-11 AU AU2013279604A patent/AU2013279604B2/en not_active Ceased
- 2013-06-11 ES ES13728180T patent/ES2795981T3/es active Active
- 2013-06-11 BR BR112014031958A patent/BR112014031958A2/pt not_active IP Right Cessation
- 2013-06-11 JP JP2015517672A patent/JP6654432B2/ja not_active Expired - Fee Related
- 2013-06-11 AU AU2013279601A patent/AU2013279601A1/en not_active Abandoned
-
2014
- 2014-12-11 IN IN10562DEN2014 patent/IN2014DN10562A/en unknown
- 2014-12-11 IN IN10561DEN2014 patent/IN2014DN10561A/en unknown
- 2014-12-16 US US14/572,654 patent/US10359433B2/en active Active
- 2014-12-16 US US14/572,445 patent/US20150132764A1/en not_active Abandoned
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