JP2015520178A5 - - Google Patents
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- Publication number
- JP2015520178A5 JP2015520178A5 JP2015515526A JP2015515526A JP2015520178A5 JP 2015520178 A5 JP2015520178 A5 JP 2015520178A5 JP 2015515526 A JP2015515526 A JP 2015515526A JP 2015515526 A JP2015515526 A JP 2015515526A JP 2015520178 A5 JP2015520178 A5 JP 2015520178A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- soluble peptide
- composition according
- motomeko
- preventing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 10
- 201000011510 cancer Diseases 0.000 claims 6
- 206010008958 Chronic lymphocytic leukaemia Diseases 0.000 claims 4
- 208000000429 Leukemia, Lymphocytic, Chronic, B-Cell Diseases 0.000 claims 4
- 206010024324 Leukaemias Diseases 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 150000007523 nucleic acids Chemical class 0.000 claims 2
- 108010017447 4N1K peptide Proteins 0.000 claims 1
- 150000001413 amino acids Chemical class 0.000 claims 1
- 108090000765 processed proteins & peptides Proteins 0.000 claims 1
- 102000004196 processed proteins & peptides Human genes 0.000 claims 1
Claims (13)
- アミノ酸配列：ＫＲＦＹＶＶＭＷＫＫ（配列番号１）又はその機能保存的変異体を含む可溶性ペプチドを含む、癌を防止又は処置するための医薬組成物。
- 可溶性ペプチドが、１、２、又は３アミノ酸、配列番号１と異なりうる、請求項１記載の医薬組成物。
- 可溶性ペプチドがアミノ酸配列配列番号１にある、請求項１記載の医薬組成物。
- 癌が白血病である、請求項１〜３のいずれか一項記載の医薬組成物。
- 白血病がＢ慢性リンパ球性白血病（ＣＬＬ）である、請求項４記載の医薬組成物。
- ＣＬＬが難治性ＣＬＬである、請求項５記載の医薬組成物。
- 請求項１〜６のいずれか一項記載の可溶性ペプチドをコードする核酸を含む、癌を防止又は処置するための医薬組成物。
- 請求項７記載の核酸を含む発現ベクターを含む、癌を防止又は処置するための医薬組成物。
- 請求項８記載の発現ベクターを含む宿主細胞を含む、癌を防止又は処置するための医薬組成物。
- 式（Ｉ）：
の可溶性ペプチド。 - 式（ＩＩ）：
の可溶性ペプチド。 - 式（ＩＩＩ）：
の可溶性ペプチド。 - 請求項１０〜１２のいずれか一項記載の可溶性ペプチドを含む、癌を防止又は処置するための医薬組成物。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12305636 | 2012-06-06 | ||
| EP12305636.8 | 2012-06-06 | ||
| PCT/EP2013/061727 WO2013182650A1 (en) | 2012-06-06 | 2013-06-06 | Method and pharmaceutical composition for use in the treatment of cancer |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017224767A Division JP2018057394A (ja) | 2012-06-06 | 2017-11-22 | 癌の処置における使用のための方法及び医薬的組成物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015520178A JP2015520178A (ja) | 2015-07-16 |
| JP2015520178A5 true JP2015520178A5 (ja) | 2016-07-28 |
Family
ID=48669879
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015515526A Pending JP2015520178A (ja) | 2012-06-06 | 2013-06-06 | 癌の処置における使用のための方法及び医薬的組成物 |
| JP2017224767A Pending JP2018057394A (ja) | 2012-06-06 | 2017-11-22 | 癌の処置における使用のための方法及び医薬的組成物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017224767A Pending JP2018057394A (ja) | 2012-06-06 | 2017-11-22 | 癌の処置における使用のための方法及び医薬的組成物 |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US9198949B2 (ja) |
| EP (2) | EP3434276A1 (ja) |
| JP (2) | JP2015520178A (ja) |
| CN (1) | CN104519898A (ja) |
| IN (1) | IN2014DN09963A (ja) |
| WO (1) | WO2013182650A1 (ja) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014160183A1 (en) * | 2013-03-13 | 2014-10-02 | The United States Of America,As Represented By The Secretary,Department Of Health And Human Services | Methods for modulating chemotherapeutic cytotoxicity |
| US11142548B2 (en) | 2016-05-10 | 2021-10-12 | Sorbonne Universite | Agents that activate CD47 and their use in the treatment of inflammation |
| EP3243522A1 (en) * | 2016-05-10 | 2017-11-15 | Université Pierre et Marie Curie (Paris 6) | Agonist agents of cd47 inducing programmed cell death and their use in the treatments of diseases associated with defects in programmed cell death |
| US11759496B2 (en) | 2016-05-10 | 2023-09-19 | Philippe Karoyan | Compounds and pharmaceutical use thereof in the treatment of cancer |
| CN107703109B (zh) * | 2016-08-08 | 2021-01-15 | 华东理工大学 | 二维硫化钼多肽复合材料及其在靶向cd47癌症标记中的应用 |
| EP3650036A1 (en) | 2018-11-06 | 2020-05-13 | Sorbonne Universite | Synthetic peptides inducing immunogenic cell death |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU643427B2 (en) | 1988-10-31 | 1993-11-18 | Immunex Corporation | Interleukin-4 receptors |
| AU651596B2 (en) | 1990-06-05 | 1994-07-28 | Immunex Corporation | Type II interleukin-1 receptors |
| US5595756A (en) * | 1993-12-22 | 1997-01-21 | Inex Pharmaceuticals Corporation | Liposomal compositions for enhanced retention of bioactive agents |
| AU684348B2 (en) | 1994-06-07 | 1997-12-11 | Nihon Medi-Physics Co., Ltd. | Tumor affinity peptide, and radioactive diagnostic agent and adioactive therapeutic agent containing the peptide |
| US5610271A (en) * | 1995-06-07 | 1997-03-11 | Torrey Pines Institute For Molecular Studies | Kappa receptor selective opioid peptides |
| US6074849A (en) | 1995-07-19 | 2000-06-13 | Genetics Institute, Inc. | Polynucleotides encoding human CTLA-8 related proteins |
| JP4184437B2 (ja) * | 1996-11-27 | 2008-11-19 | ボストン ハート ファウンデイション インコーポレイテッド | 新規な低密度リポ蛋白質結合性蛋白質並びにアテローム性動脈硬化症の診断及び治療におけるそれらの利用 |
| US6579520B2 (en) | 1998-05-15 | 2003-06-17 | Genentech, Inc. | IL-17 related mammalian cytokine polypeptides (IL-17E) |
| US6569645B2 (en) | 1999-05-14 | 2003-05-27 | Genentech, Inc. | IL-17 homologous polypeptides and therapeutic uses thereof |
| EP1283850A2 (en) * | 2000-05-26 | 2003-02-19 | Beth Israel Deaconess Medical Center | Thrombospondin type 1 repeat polypeptides |
| US8691780B2 (en) * | 2005-02-17 | 2014-04-08 | The Board Of Trustees Of The Leland Stanford Junior University | Txr1 and enhanced taxane sensitivity based on the modulation of a pathway mediated thereby |
| JP2009013142A (ja) | 2007-07-09 | 2009-01-22 | Kyoto Univ | 徐放用メソポーラスシリカ |
| JP5661988B2 (ja) | 2008-02-26 | 2015-01-28 | 株式会社ペプタイドドア | ムスカリンレセプター活性化剤及びペプチド |
-
2013
- 2013-06-06 CN CN201380029870.5A patent/CN104519898A/zh active Pending
- 2013-06-06 EP EP18192533.0A patent/EP3434276A1/en active Pending
- 2013-06-06 EP EP13730146.1A patent/EP2858660B1/en not_active Not-in-force
- 2013-06-06 IN IN9963DEN2014 patent/IN2014DN09963A/en unknown
- 2013-06-06 WO PCT/EP2013/061727 patent/WO2013182650A1/en active Application Filing
- 2013-06-06 JP JP2015515526A patent/JP2015520178A/ja active Pending
- 2013-06-06 US US14/406,091 patent/US9198949B2/en active Active
-
2015
- 2015-10-05 US US14/874,657 patent/US20160039908A1/en not_active Abandoned
-
2017
- 2017-08-28 US US15/687,692 patent/US20170362302A1/en not_active Abandoned
- 2017-11-22 JP JP2017224767A patent/JP2018057394A/ja active Pending
-
2018
- 2018-10-16 US US16/161,931 patent/US10759843B2/en active Active
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