JP2015519134A5 - - Google Patents

Info

Publication number

JP2015519134A5

JP2015519134A5 JP2015514302A JP2015514302A JP2015519134A5 JP 2015519134 A5 JP2015519134 A5 JP 2015519134A5 JP 2015514302 A JP2015514302 A JP 2015514302A JP 2015514302 A JP2015514302 A JP 2015514302A JP 2015519134 A5 JP2015519134 A5 JP 2015519134A5

Authority

JP

Japan

Prior art keywords

composition

hyaluronic acid

composition according

calcium phosphate

total weight

Prior art date

2013-05-30

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

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• KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims 9
• 229920002674 hyaluronan Polymers 0.000 claims 9
• 229960003160 hyaluronic acid Drugs 0.000 claims 9
• 229910000389 calcium phosphate Inorganic materials 0.000 claims 6
• 239000001506 calcium phosphate Substances 0.000 claims 6
• 235000011010 calcium phosphates Nutrition 0.000 claims 6
• 229910052500 inorganic mineral Inorganic materials 0.000 claims 6
• 239000011707 mineral Substances 0.000 claims 6
• QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 5
• MSWZFWKMSRAUBD-IVMDWMLBSA-N 2-amino-2-deoxy-D-glucopyranose Chemical compound N[C@H]1C(O)O[C@H](CO)[C@@H](O)[C@@H]1O MSWZFWKMSRAUBD-IVMDWMLBSA-N 0.000 claims 4
• MSWZFWKMSRAUBD-UHFFFAOYSA-N beta-D-galactosamine Natural products NC1C(O)OC(CO)C(O)C1O MSWZFWKMSRAUBD-UHFFFAOYSA-N 0.000 claims 4
• 229960002442 glucosamine Drugs 0.000 claims 4
• 239000000906 photoactive agent Substances 0.000 claims 4
• GNBHRKFJIUUOQI-UHFFFAOYSA-N fluorescein Chemical class O1C(=O)C2=CC=CC=C2C21C1=CC=C(O)C=C1OC1=CC(O)=CC=C21 GNBHRKFJIUUOQI-UHFFFAOYSA-N 0.000 claims 2
• 210000000988 bone and bone Anatomy 0.000 claims 1
• 230000008468 bone growth Effects 0.000 claims 1
• -1 calcium phosphate mineral Chemical class 0.000 claims 1
• SEACYXSIPDVVMV-UHFFFAOYSA-L eosin Y Chemical group [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=C(Br)C(=O)C(Br)=C2OC2=C(Br)C([O-])=C(Br)C=C21 SEACYXSIPDVVMV-UHFFFAOYSA-L 0.000 claims 1
• 229910052588 hydroxylapatite Inorganic materials 0.000 claims 1
• XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 1
• 230000001172 regenerating effect Effects 0.000 claims 1
• 239000001018 xanthene dye Substances 0.000 claims 1