JP2015519134A - 生体光骨再建のための組成物および方法 - Google Patents

生体光骨再建のための組成物および方法 Download PDF

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Publication number
JP2015519134A
JP2015519134A JP2015514302A JP2015514302A JP2015519134A JP 2015519134 A JP2015519134 A JP 2015519134A JP 2015514302 A JP2015514302 A JP 2015514302A JP 2015514302 A JP2015514302 A JP 2015514302A JP 2015519134 A JP2015519134 A JP 2015519134A
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JP
Japan
Prior art keywords
composition
hyaluronic acid
calcium phosphate
weight
bone
Prior art date
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Pending
Application number
JP2015514302A
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English (en)
Japanese (ja)
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JP2015519134A5 (https=
Inventor
ルピス、ニコラオス
ピエルガッリーニ、レミージョ
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Klox Technologies Inc
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Klox Technologies Inc
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Publication of JP2015519134A publication Critical patent/JP2015519134A/ja
Publication of JP2015519134A5 publication Critical patent/JP2015519134A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057—Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
    • A61K31/728—Hyaluronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/42—Phosphorus; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00—Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/884—Preparations for artificial teeth, for filling teeth or for capping teeth comprising natural or synthetic resins
    • A61K6/898—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/001—Use of materials characterised by their function or physical properties
    • A61L24/0015—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
    • A61L24/0047—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L24/0073—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix
    • A61L24/0084—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material with a macromolecular matrix containing fillers of phosphorus-containing inorganic compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/40—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
    • A61L27/44—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
    • A61L27/46—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix with phosphorus-containing inorganic fillers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N5/0613—Apparatus adapted for a specific treatment
    • A61N5/062—Photodynamic therapy, i.e. excitation of an agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/32—Phosphorus-containing compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/0008—Organic ingredients according to more than one of the "one dot" groups of C08K5/01 - C08K5/59
    • C08K5/0041—Optical brightening agents, organic pigments
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K5/00—Use of organic ingredients
    • C08K5/04—Oxygen-containing compounds
    • C08K5/15—Heterocyclic compounds having oxygen in the ring
    • C08K5/151—Heterocyclic compounds having oxygen in the ring having one oxygen atom in the ring
    • C08K5/1545—Six-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K6/00—Preparations for dentistry
    • A61K6/80—Preparations for artificial teeth, for filling teeth or for capping teeth
    • A61K6/831—Preparations for artificial teeth, for filling teeth or for capping teeth comprising non-metallic elements or compounds thereof, e.g. carbon
    • A61K6/838—Phosphorus compounds, e.g. apatite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/442—Colorants, dyes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/06—Radiation therapy using light
    • A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
    • A61N2005/0662—Visible light
    • A61N2005/0663—Coloured light
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08K—Use of inorganic or non-macromolecular organic substances as compounding ingredients
    • C08K3/00—Use of inorganic substances as compounding ingredients
    • C08K3/32—Phosphorus-containing compounds
    • C08K2003/321—Phosphates
    • C08K2003/325—Calcium, strontium or barium phosphate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Composite Materials (AREA)
  • Transplantation (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plastic & Reconstructive Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biochemistry (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2015514302A 2012-05-30 2013-05-30 生体光骨再建のための組成物および方法 Pending JP2015519134A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261653101P 2012-05-30 2012-05-30
US61/653,101 2012-05-30
US201361777894P 2013-03-12 2013-03-12
US61/777,894 2013-03-12
PCT/CA2013/000532 WO2013177686A1 (en) 2012-05-30 2013-05-30 Compositions and methods for biophotonic bone reconstruction

Publications (2)

Publication Number Publication Date
JP2015519134A true JP2015519134A (ja) 2015-07-09
JP2015519134A5 JP2015519134A5 (https=) 2016-07-14

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015514302A Pending JP2015519134A (ja) 2012-05-30 2013-05-30 生体光骨再建のための組成物および方法

Country Status (17)

Country Link
US (1) US11426463B2 (https=)
EP (1) EP2854853B1 (https=)
JP (1) JP2015519134A (https=)
KR (1) KR20150023294A (https=)
CN (1) CN104394888A (https=)
AU (1) AU2013270353A1 (https=)
BR (1) BR112014029801A2 (https=)
CA (1) CA2873068A1 (https=)
HK (1) HK1207300A1 (https=)
IL (1) IL235687A0 (https=)
IN (1) IN2014DN09950A (https=)
MX (1) MX2014014458A (https=)
NZ (1) NZ701667A (https=)
RU (1) RU2014147975A (https=)
SG (1) SG11201407276RA (https=)
WO (1) WO2013177686A1 (https=)
ZA (1) ZA201408483B (https=)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017511393A (ja) * 2014-01-24 2017-04-20 ザ プロクター アンド ギャンブル カンパニー 光活性剤
JP2017076494A (ja) * 2015-10-14 2017-04-20 三菱電機株式会社 光源ユニット及び照明装置
JP2023542733A (ja) * 2020-09-29 2023-10-11 シージー バイオ カンパニー，リミテッド 高弾性のリン酸カルシウム系注入型骨移植材組成物及びその製造方法

Families Citing this family (4)

* Cited by examiner, † Cited by third party
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CA2944201A1 (en) * 2014-04-01 2015-10-08 Klox Technologies Inc. Tissue filler compositions and methods of use
EP3581697B1 (en) 2018-06-11 2023-02-22 The Procter & Gamble Company Photoactivating device for washing machine
KR20260032794A (ko) * 2024-08-30 2026-03-10 주식회사 덴큐임플란트 임플란트 서지컬 키트의 드릴링 온도를 이용한 인공지능 기반 골질 판별 시스템
CN119935694A (zh) * 2025-01-24 2025-05-06 北京大学第三医院（北京大学第三临床医学院） 一种骨组织多重特殊染色分析方法及其应用

Citations (7)

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JP2005538757A (ja) * 2002-07-31 2005-12-22 デンツプライ インターナショナル インコーポレーテッド 多孔性粒子およびキャリアゲルを含む骨修復パテ
JP2007515196A (ja) * 2003-09-23 2007-06-14 オーソ・セラピューティクス・リミテッド・ライアビリティ・カンパニー 吸収性のインプラントならびに止血および骨欠損の処置における、それらの使用
JP2007197371A (ja) * 2006-01-26 2007-08-09 Yaizu Suisankagaku Industry Co Ltd 美肌促進剤及び美容健康食品
JP2009511425A (ja) * 2005-09-02 2009-03-19 キャンピナ・ネダーランド・ホールディング・ビー．ブイ． 皮膚を加湿するための経口組成物
JP2010511474A (ja) * 2006-12-08 2010-04-15 ザ ユニバーシティ オブ ワイカト 医療用調製物
JP2010535071A (ja) * 2007-08-01 2010-11-18 ジョンズ ホプキンス ユニバーシティ 光開始組織充填剤

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AU770196B2 (en) * 1999-02-04 2004-02-12 Warsaw Orthopedic, Inc. Osteogenic paste compositions and uses thereof
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EP1585504A4 (en) 2002-11-06 2009-07-15 Azaya Therapeutics Inc Protein stabilized liposomal formulations of pharmaceutical active ingredients
ITPD20030286A1 (it) * 2003-11-27 2005-05-28 Fidia Advanced Biopolymers Srl Strutture composite multistrato contenenti acido ialuronico
US9132208B2 (en) * 2008-08-07 2015-09-15 Lifenet Health Composition for a tissue repair implant and methods of making the same
US20070269518A1 (en) * 2005-12-28 2007-11-22 Walline Katherine S Light-curable bone growth material for treating dental bone defects
US8999933B2 (en) 2006-01-18 2015-04-07 Biolitec Pharma Marketing Ltd Photodynamic cosmetic procedure and healing method
CN101677957A (zh) * 2007-02-05 2010-03-24 卡比兰生物外科公司 用于递送生物活性试剂的聚合物制剂
CN102065914A (zh) * 2008-04-15 2011-05-18 埃泰克斯公司 使用磷酸钙组合的骨接合剂的脊椎骨最小侵入性治疗(mitv)
SG177635A1 (en) * 2009-07-17 2012-03-29 Klox Technologies Inc Combination of an oxidant, a photosensitizer and a wound healing agent for oral disinfection and treatment of oral disease

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1285193A (zh) * 1999-08-18 2001-02-28 凌沛学 透明质酸口服美肤保健品的制备和应用
JP2005538757A (ja) * 2002-07-31 2005-12-22 デンツプライ インターナショナル インコーポレーテッド 多孔性粒子およびキャリアゲルを含む骨修復パテ
JP2007515196A (ja) * 2003-09-23 2007-06-14 オーソ・セラピューティクス・リミテッド・ライアビリティ・カンパニー 吸収性のインプラントならびに止血および骨欠損の処置における、それらの使用
JP2009511425A (ja) * 2005-09-02 2009-03-19 キャンピナ・ネダーランド・ホールディング・ビー．ブイ． 皮膚を加湿するための経口組成物
JP2007197371A (ja) * 2006-01-26 2007-08-09 Yaizu Suisankagaku Industry Co Ltd 美肌促進剤及び美容健康食品
JP2010511474A (ja) * 2006-12-08 2010-04-15 ザ ユニバーシティ オブ ワイカト 医療用調製物
JP2010535071A (ja) * 2007-08-01 2010-11-18 ジョンズ ホプキンス ユニバーシティ 光開始組織充填剤

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017511393A (ja) * 2014-01-24 2017-04-20 ザ プロクター アンド ギャンブル カンパニー 光活性剤
JP2017076494A (ja) * 2015-10-14 2017-04-20 三菱電機株式会社 光源ユニット及び照明装置
JP2023542733A (ja) * 2020-09-29 2023-10-11 シージー バイオ カンパニー，リミテッド 高弾性のリン酸カルシウム系注入型骨移植材組成物及びその製造方法
JP7522309B2 (ja) 2020-09-29 2024-07-24 シージー バイオ カンパニー，リミテッド 高弾性のリン酸カルシウム系注入型骨移植材組成物及びその製造方法

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Publication number Publication date
CA2873068A1 (en) 2013-12-05
HK1207300A1 (en) 2016-01-29
EP2854853A1 (en) 2015-04-08
KR20150023294A (ko) 2015-03-05
SG11201407276RA (en) 2015-03-30
ZA201408483B (en) 2015-12-23
WO2013177686A1 (en) 2013-12-05
IL235687A0 (en) 2015-01-29
CN104394888A (zh) 2015-03-04
BR112014029801A2 (pt) 2017-06-27
EP2854853B1 (en) 2019-08-21
US11426463B2 (en) 2022-08-30
EP2854853A4 (en) 2016-01-13
AU2013270353A1 (en) 2014-11-27
RU2014147975A (ru) 2016-07-20
US20150119789A1 (en) 2015-04-30
MX2014014458A (es) 2015-08-14
NZ701667A (en) 2017-05-26
IN2014DN09950A (https=) 2015-08-14

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