JP2015517524A5 - - Google Patents
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- Publication number
- JP2015517524A5 JP2015517524A5 JP2015512752A JP2015512752A JP2015517524A5 JP 2015517524 A5 JP2015517524 A5 JP 2015517524A5 JP 2015512752 A JP2015512752 A JP 2015512752A JP 2015512752 A JP2015512752 A JP 2015512752A JP 2015517524 A5 JP2015517524 A5 JP 2015517524A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- salt
- crystalline
- methyl
- monomesylate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 150000003839 salts Chemical class 0.000 claims 20
- 239000000203 mixture Substances 0.000 claims 19
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims 8
- -1 methoxy (methyl) amino Chemical group 0.000 claims 4
- 239000008194 pharmaceutical composition Substances 0.000 claims 4
- 239000004480 active ingredient Substances 0.000 claims 2
- 206010061041 Chlamydial infection Diseases 0.000 claims 1
- 206010019375 Helicobacter infections Diseases 0.000 claims 1
- 208000037942 Methicillin-resistant Staphylococcus aureus infection Diseases 0.000 claims 1
- 208000008469 Peptic Ulcer Diseases 0.000 claims 1
- 229910052797 bismuth Inorganic materials 0.000 claims 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 claims 1
- 208000011906 peptic ulcer disease Diseases 0.000 claims 1
- 229940126409 proton pump inhibitor Drugs 0.000 claims 1
- 239000000612 proton pump inhibitor Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261646754P | 2012-05-14 | 2012-05-14 | |
| US61/646,754 | 2012-05-14 | ||
| PCT/US2013/040933 WO2013173326A1 (en) | 2012-05-14 | 2013-05-14 | Methods of using (4s,4as,5ar,12as)-4- dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015517524A JP2015517524A (ja) | 2015-06-22 |
| JP2015517524A5 true JP2015517524A5 (enExample) | 2016-06-30 |
Family
ID=49548796
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512752A Pending JP2015517524A (ja) | 2012-05-14 | 2013-05-14 | （４Ｓ，４ａＳ，５ａＲ，１２ａＳ）−４−ジメチルアミノ−３，１０，１２，１２ａ−テトラヒドロキシ−７−［（メトキシ（メチル）アミノ）−メチル］−１，１１−ジオキソ−１，４，４ａ，５，５ａ，６，１１，１２ａ−オクタヒドロ−ナフタセン−２−カルボン酸アミドの使用方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20130302442A1 (enExample) |
| EP (1) | EP2849757A4 (enExample) |
| JP (1) | JP2015517524A (enExample) |
| AU (1) | AU2013262991A1 (enExample) |
| CA (1) | CA2873412A1 (enExample) |
| WO (1) | WO2013173326A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012155146A1 (en) * | 2011-05-12 | 2012-11-15 | Paratek Pharmaceuticals, Inc. | Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same |
| EP4268897A3 (en) * | 2015-03-24 | 2024-01-03 | Paratek Pharmaceuticals, Inc. | Minocycline compounds for biodefense |
| US12297161B2 (en) * | 2018-04-06 | 2025-05-13 | Almirall, Llc | Process for making sarecycline hydrochloride |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0375068A1 (en) * | 1988-12-23 | 1990-06-27 | Gist-Brocades N.V. | Combining bismuth compounds and tetracyclines |
| US7871793B2 (en) * | 2004-02-20 | 2011-01-18 | Burnham Institute For Medical Research | Antimicrobial carbohydrates and methods of using same |
| AU2007338681B2 (en) * | 2006-12-21 | 2013-09-26 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of inflammatory skin disorders |
| ES2548261T3 (es) * | 2006-12-21 | 2015-10-15 | Paratek Pharmaceuticals, Inc. | Derivados de tetraciclina para el tratamiento de infecciones bacterianas, virales y parasitarias |
| JP5944825B2 (ja) * | 2009-08-28 | 2016-07-05 | テトラフェース ファーマシューティカルズ，インコーポレイテッド | テトラサイクリン化合物 |
| WO2012021829A1 (en) * | 2010-08-12 | 2012-02-16 | Tetraphase Pharmaceuticals, Inc. | Methods of treating bacterial infections |
| WO2012155146A1 (en) * | 2011-05-12 | 2012-11-15 | Paratek Pharmaceuticals, Inc. | Crystalline salts of (4s,4as,5ar,12as)-4-dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide and methods of using the same |
-
2013
- 2013-05-14 JP JP2015512752A patent/JP2015517524A/ja active Pending
- 2013-05-14 EP EP13790638.4A patent/EP2849757A4/en not_active Withdrawn
- 2013-05-14 CA CA2873412A patent/CA2873412A1/en not_active Abandoned
- 2013-05-14 US US13/893,717 patent/US20130302442A1/en not_active Abandoned
- 2013-05-14 AU AU2013262991A patent/AU2013262991A1/en not_active Abandoned
- 2013-05-14 WO PCT/US2013/040933 patent/WO2013173326A1/en not_active Ceased
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