JP2015516451A5 - - Google Patents

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Publication number
JP2015516451A5
JP2015516451A5 JP2015511957A JP2015511957A JP2015516451A5 JP 2015516451 A5 JP2015516451 A5 JP 2015516451A5 JP 2015511957 A JP2015511957 A JP 2015511957A JP 2015511957 A JP2015511957 A JP 2015511957A JP 2015516451 A5 JP2015516451 A5 JP 2015516451A5
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JP
Japan
Prior art keywords
pain
pharmaceutical dosage
weeks
hours
refers
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JP2015511957A
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English (en)
Japanese (ja)
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JP2015516451A (ja
JP6116678B2 (ja
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Priority claimed from PCT/EP2013/001470 external-priority patent/WO2013170971A1/en
Publication of JP2015516451A publication Critical patent/JP2015516451A/ja
Publication of JP2015516451A5 publication Critical patent/JP2015516451A5/ja
Application granted granted Critical
Publication of JP6116678B2 publication Critical patent/JP6116678B2/ja
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JP2015511957A 2012-05-18 2013-05-16 (1r,4r)−6’−フルオロ−N,N−ジメチル−4−フェニル−4’,9’−ジヒドロ−3’H−スピロ[シクロヘキサン−1,1’−ピラノ[3,4,b]インドール]−4−アミンおよびNSARを含む医薬組成物 Active JP6116678B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12003895 2012-05-18
EP12003895.5 2012-05-18
PCT/EP2013/001470 WO2013170971A1 (en) 2012-05-18 2013-05-16 Pharmaceutical composition comprising (1r,4r)-6'-fluoro-n,n-dimethyl-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano [3,4,b]indol]-4-amine and a nsar

Publications (3)

Publication Number Publication Date
JP2015516451A JP2015516451A (ja) 2015-06-11
JP2015516451A5 true JP2015516451A5 (https=) 2017-03-09
JP6116678B2 JP6116678B2 (ja) 2017-04-19

Family

ID=48520892

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2015511957A Active JP6116678B2 (ja) 2012-05-18 2013-05-16 (1r,4r)−6’−フルオロ−N,N−ジメチル−4−フェニル−4’,9’−ジヒドロ−3’H−スピロ[シクロヘキサン−1,1’−ピラノ[3,4,b]インドール]−4−アミンおよびNSARを含む医薬組成物

Country Status (22)

Country Link
US (1) US8912226B2 (https=)
EP (1) EP2849747B1 (https=)
JP (1) JP6116678B2 (https=)
CN (1) CN104284660A (https=)
AU (1) AU2013262077B2 (https=)
BR (1) BR112014028566A2 (https=)
CA (1) CA2873867A1 (https=)
CY (1) CY1119781T1 (https=)
DK (1) DK2849747T3 (https=)
EA (1) EA027145B1 (https=)
ES (1) ES2658217T3 (https=)
HR (1) HRP20171725T1 (https=)
HU (1) HUE034658T2 (https=)
IL (1) IL235653B (https=)
LT (1) LT2849747T (https=)
MX (1) MX356493B (https=)
NO (1) NO2849747T3 (https=)
PL (1) PL2849747T3 (https=)
PT (1) PT2849747T (https=)
RS (1) RS56788B1 (https=)
SI (1) SI2849747T1 (https=)
WO (1) WO2013170971A1 (https=)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6673924B2 (ja) 2015-01-23 2020-03-25 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング 肝機能障害および/または腎機能障害を有する対象における疼痛を治療するためのセブラノパドール
WO2016168388A2 (en) 2015-04-14 2016-10-20 Palatin Technologies, Inc. Therapies for obesity, diabetes and related indications
JP7373904B2 (ja) 2016-02-29 2023-11-06 パーク・セラピューティクス・インコーポレイテッド セブラノパドールの滴定

Family Cites Families (31)

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EP0068838B1 (en) 1981-06-26 1986-09-17 The Upjohn Company Analgesic process and composition
US4389393A (en) 1982-03-26 1983-06-21 Forest Laboratories, Inc. Sustained release therapeutic compositions based on high molecular weight hydroxypropylmethylcellulose
US4404208A (en) * 1982-06-30 1983-09-13 E. I. Du Pont De Nemours And Company Analgesic mixture of nalbuphine and tiflamizole
US4765989A (en) 1983-05-11 1988-08-23 Alza Corporation Osmotic device for administering certain drugs
US4612008A (en) 1983-05-11 1986-09-16 Alza Corporation Osmotic device with dual thermodynamic activity
US4783337A (en) 1983-05-11 1988-11-08 Alza Corporation Osmotic system comprising plurality of members for dispensing drug
KR0156231B1 (ko) 1989-05-22 1998-11-16 존 레이 비핀 인도메타신의 2가 전이 금속염을 함유하는 조성물
US5472711A (en) 1992-07-30 1995-12-05 Edward Mendell Co., Inc. Agglomerated hydrophilic complexes with multi-phasic release characteristics
US5330761A (en) 1993-01-29 1994-07-19 Edward Mendell Co. Inc. Bioadhesive tablet for non-systemic use products
US5455046A (en) 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5399362A (en) 1994-04-25 1995-03-21 Edward Mendell Co., Inc. Once-a-day metoprolol oral dosage form
US5914129A (en) 1996-07-23 1999-06-22 Mauskop; Alexander Analgesic composition for treatment of migraine headaches
EP1219304B1 (de) 2000-12-28 2004-10-20 Fresenius Kabi Austria GmbH Stabile Infusionslösung von Diclofenac-Salzen, deren Herstellung und Verwendung
EP1374906B1 (en) 2002-06-17 2007-04-18 CHIESI FARMACEUTICI S.p.A. A process for the preparation of piroxicam: beta-cyclodextrin inclusion compounds
DE10252667A1 (de) 2002-11-11 2004-05-27 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
DE10257824B4 (de) 2002-12-10 2004-11-11 Kochem, Hans-Günter, Dr. Zusammensetzung zur Schmerzbehandlung, insbesondere zur Behandlung von Gelenkschmerzen
US20100297252A1 (en) 2003-03-03 2010-11-25 Elan Pharma International Ltd. Nanoparticulate meloxicam formulations
US7132452B2 (en) 2003-03-10 2006-11-07 Fang-Yu Lee Topical formulation having effects on alleviating pain/inflammation caused by herpes virus infection
DE10360792A1 (de) 2003-12-23 2005-07-28 Grünenthal GmbH Spirocyclische Cyclohexan-Derivate
CA2612299A1 (en) * 2005-06-17 2006-12-21 Pfizer Inc. Alpha-(aryl-or heteroaryl-methyl)-beta piperidino propanamide compounds as orl1-receptor antagonists
ATE502629T1 (de) * 2006-04-28 2011-04-15 Gruenenthal Gmbh Pharmazeutische kombination mit 3- (3- dimethylamino-1-ethyl-2-methyl-propyl) phenol und einem nsar
CN101147735A (zh) 2006-09-19 2008-03-26 沈阳华泰药物研究有限公司 注射用药物组合物及其药盒
DE102006046745A1 (de) 2006-09-29 2008-04-03 Grünenthal GmbH Gemischte ORL1/µ-Agonisten zur Behandlung von Schmerz
DE102006056458A1 (de) 2006-11-28 2008-05-29 Grünenthal GmbH Arzneimittelzubereitung von Tramadol und Acetaminophen
ES2416723T3 (es) * 2007-10-09 2013-08-02 Merck Patent Gmbh Composiciones farmacéuticas que contienen benfotiamina y gabapentina
CN100560061C (zh) 2008-06-20 2009-11-18 海南锦瑞制药股份有限公司 一种氯诺昔康冻干粉针剂及其制备方法
KR101730924B1 (ko) * 2008-09-05 2017-04-27 그뤼넨탈 게엠베하 3-(3-디메틸아미노-1-에틸-2-메틸-프로필)-페놀과 항간질제의 약제학적 병용물
AR073495A1 (es) * 2008-09-05 2010-11-10 Gruenenthal Gmbh Combinacion farmaceutica que contiene el 6-dimetilaminometil-1- (3-metoxi-fenil)-ciclohexano-1,3-diol y un nsaid
KR20130097173A (ko) * 2010-08-04 2013-09-02 그뤼넨탈 게엠베하 신경병증성 통증을 치료하기 위한 6’­플루오로­(N­메틸­ 또는 N,N­디메틸­)­4­페닐­4’,9’­디하이드로­3’H­스피로[사이클로헥산­1,1’­피라노[3,4,b]인돌]­4­아민을 포함하는 약제학적 투여형
WO2012016703A2 (en) * 2010-08-04 2012-02-09 Grünenthal GmbH Pharmaceutical dosage form comprising 6'-fluoro-(n-methyl- or n,n-dimethyl-)-4-phenyl-4',9'-dihydro-3'h-spiro[cyclohexane-1,1'-pyrano[3,4,b]indol]-4-amine
AU2011287952B2 (en) * 2010-08-04 2014-08-21 Grünenthal GmbH Pharmaceutical dosage form comprising 6'-fluoro-(N-methyl- or N,N-dimethyl-)-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane- 1,1'-pyrano[3,4,b]indol]-4-amine

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