JP2015516264A5 - - Google Patents
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- Publication number
- JP2015516264A5 JP2015516264A5 JP2015512646A JP2015512646A JP2015516264A5 JP 2015516264 A5 JP2015516264 A5 JP 2015516264A5 JP 2015512646 A JP2015512646 A JP 2015512646A JP 2015512646 A JP2015512646 A JP 2015512646A JP 2015516264 A5 JP2015516264 A5 JP 2015516264A5
- Authority
- JP
- Japan
- Prior art keywords
- antigen
- antibody
- binding fragment
- particles
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000427 antigen Substances 0.000 claims 12
- 102000036639 antigens Human genes 0.000 claims 12
- 108091007433 antigens Proteins 0.000 claims 12
- 239000012634 fragment Substances 0.000 claims 12
- 238000000034 method Methods 0.000 claims 9
- 239000002245 particle Substances 0.000 claims 9
- 229920000642 polymer Polymers 0.000 claims 7
- 239000013060 biological fluid Substances 0.000 claims 6
- 239000003446 ligand Substances 0.000 claims 6
- 239000008280 blood Substances 0.000 claims 3
- 210000004369 blood Anatomy 0.000 claims 3
- SJECZPVISLOESU-UHFFFAOYSA-N 3-trimethoxysilylpropan-1-amine Chemical compound CO[Si](OC)(OC)CCCN SJECZPVISLOESU-UHFFFAOYSA-N 0.000 claims 2
- 239000003431 cross linking reagent Substances 0.000 claims 2
- 102000004169 proteins and genes Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 108090000695 Cytokines Proteins 0.000 claims 1
- 102000004127 Cytokines Human genes 0.000 claims 1
- 108090001005 Interleukin-6 Proteins 0.000 claims 1
- 102000005789 Vascular Endothelial Growth Factors Human genes 0.000 claims 1
- 108010019530 Vascular Endothelial Growth Factors Proteins 0.000 claims 1
- 210000001175 cerebrospinal fluid Anatomy 0.000 claims 1
- 239000012530 fluid Substances 0.000 claims 1
- 239000007863 gel particle Substances 0.000 claims 1
- 239000000017 hydrogel Substances 0.000 claims 1
- 230000002757 inflammatory effect Effects 0.000 claims 1
- 239000011859 microparticle Substances 0.000 claims 1
- 239000002105 nanoparticle Substances 0.000 claims 1
- 210000002381 plasma Anatomy 0.000 claims 1
- 229920000435 poly(dimethylsiloxane) Polymers 0.000 claims 1
- 229920001296 polysiloxane Polymers 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 210000002966 serum Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261646674P | 2012-05-14 | 2012-05-14 | |
| US61/646,674 | 2012-05-14 | ||
| PCT/US2013/031744 WO2013172966A1 (en) | 2012-05-14 | 2013-03-14 | Systems and methods for extracorporeal blood modification |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015516264A JP2015516264A (ja) | 2015-06-11 |
| JP2015516264A5 true JP2015516264A5 (https=) | 2016-05-12 |
| JP6404211B2 JP6404211B2 (ja) | 2018-10-10 |
Family
ID=49584139
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015512646A Active JP6404211B2 (ja) | 2012-05-14 | 2013-03-14 | 体外血液改質のためのシステムおよび方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US20150132312A1 (https=) |
| EP (1) | EP2849817B1 (https=) |
| JP (1) | JP6404211B2 (https=) |
| ES (1) | ES2725573T3 (https=) |
| WO (1) | WO2013172966A1 (https=) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20150071935A1 (en) * | 2012-05-27 | 2015-03-12 | Marv Enterprises, LLC | Treatment for the rapid amelioration of clinical depression |
| ES2660595T3 (es) * | 2013-06-07 | 2018-03-23 | Baxter International Inc. | Inmovilización de un agente activo sobre un sustrato empleando compuestos que incluyen grupos trihidroxifenilo |
| BR112016013876B1 (pt) * | 2013-12-27 | 2022-03-22 | Eliaz Therapeutics, Inc. | Dispositivo para realização de plasmaferese |
| DE102015207228A1 (de) * | 2015-04-21 | 2016-10-27 | Vetter Pharma-Fertigung GmbH & Co. KG | Primärpackmittel und Verfahren zur Herstellung eines Primärpackmittels |
| US10064653B2 (en) | 2015-06-08 | 2018-09-04 | The Board Of Trustees Of The Leland Stanford Junior University | Intravascular magnetic wire for detection, retrieval or elimination of disease-associated biomarkers and toxins |
| JP7429343B2 (ja) | 2018-01-05 | 2024-02-08 | パス イーエックス，インク． | 流体からの疾患材料の捕捉および除去のためのデバイス |
| JP2022548026A (ja) * | 2019-09-13 | 2022-11-16 | ザ・トラスティーズ・オブ・インディアナ・ユニバーシティー | 血液中のａｄｍａを調節するデバイスおよび方法 |
| US12521475B2 (en) * | 2020-04-08 | 2026-01-13 | Arizona Board Of Regents On Behalf Of Arizona State University | Method, device, and product for treating a body fluid of a patient with an inflammatory cytokine storm by binding an antibody to a cytokine antigen in the body fluid to form an antigen-antibody complex that is removed from the body fluid to reduce the amount of the cytokines in the body fluid |
| CN112090410B (zh) * | 2020-07-29 | 2023-11-10 | 健帆生物科技集团股份有限公司 | 具有互穿网络包膜的血液净化吸附剂、制备方法及灌流器 |
| WO2024030085A1 (en) * | 2022-08-05 | 2024-02-08 | Innowayrg Arastirma Gelistirme Ve Danismanlik Hizmetleri Sanayi Ve Ticaret Anonim Sirketi | A device for cleaning heavy metal-bound mediators in body fluids and organs |
| WO2024076704A1 (en) * | 2022-10-05 | 2024-04-11 | Immunicom, Inc. | Il-6 removal |
| KR102694305B1 (ko) * | 2023-05-23 | 2024-08-13 | 주식회사 월드바이오텍 | 치열교정 브라켓 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3523615A1 (de) * | 1985-07-02 | 1987-01-15 | Cytomed Medizintechnik | Medizinisches geraet, insbesondere kanuele, katheter oder implantat |
| US5589563A (en) * | 1992-04-24 | 1996-12-31 | The Polymer Technology Group | Surface-modifying endgroups for biomedical polymers |
| EP1315551B1 (en) * | 1999-06-03 | 2015-11-04 | Advanced Extravascular Systems | One step removal of unwanted molecules from circulating blood |
| US6969367B2 (en) * | 2000-02-02 | 2005-11-29 | Xepmed, Inc. | Extracorporeal pathogen reduction system |
| US20030120202A1 (en) * | 2001-12-21 | 2003-06-26 | Gordon Lucas S. | Magnetic extracorporeal circuit for removal of medical agents |
| US20040028687A1 (en) * | 2002-01-15 | 2004-02-12 | Waelti Ernst Rudolf | Methods and compositions for the targeted delivery of therapeutic substances to specific cells and tissues |
| US8211310B2 (en) * | 2006-11-20 | 2012-07-03 | Cytosorbents, Inc. | Size-selective polymer system |
| US20090191175A1 (en) * | 2006-11-21 | 2009-07-30 | University Of Southern California | Therapeutic methods using peg-conjugated agents and devices for performing the same |
| US20110008404A1 (en) * | 2007-12-19 | 2011-01-13 | Georgia Tech Research Corporation | Modification Of Biomaterials With Microgel Films |
| CA2728270A1 (en) * | 2008-06-17 | 2009-12-23 | Georgia Tech Research Corporation | Superparamagnetic nanoparticles for removal of cells, pathogens or viruses |
| US8454547B2 (en) * | 2009-02-25 | 2013-06-04 | The Invention Science Fund I, Llc | Device, system, and method for controllably reducing inflammatory mediators in a subject |
| CA2776613A1 (en) * | 2009-10-07 | 2011-04-14 | University Of Pittsburgh - Of The Commonwealth System Of Higher Educatio N | Devices, systems and methods for cell modification |
| WO2011112873A2 (en) * | 2010-03-10 | 2011-09-15 | Paul Tebbey | Extracorporeal immunoadsorption treatment |
-
2013
- 2013-03-14 US US14/400,606 patent/US20150132312A1/en not_active Abandoned
- 2013-03-14 EP EP13791497.4A patent/EP2849817B1/en active Active
- 2013-03-14 ES ES13791497T patent/ES2725573T3/es active Active
- 2013-03-14 WO PCT/US2013/031744 patent/WO2013172966A1/en not_active Ceased
- 2013-03-14 JP JP2015512646A patent/JP6404211B2/ja active Active
-
2019
- 2019-05-16 US US16/413,874 patent/US20200101214A1/en not_active Abandoned
- 2019-12-20 US US16/724,102 patent/US20200171232A1/en not_active Abandoned
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