JP2015514760A - 胚性幹細胞微小胞を用いる眼科治療法 - Google Patents
胚性幹細胞微小胞を用いる眼科治療法 Download PDFInfo
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- JP2015514760A JP2015514760A JP2015506995A JP2015506995A JP2015514760A JP 2015514760 A JP2015514760 A JP 2015514760A JP 2015506995 A JP2015506995 A JP 2015506995A JP 2015506995 A JP2015506995 A JP 2015506995A JP 2015514760 A JP2015514760 A JP 2015514760A
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0603—Embryonic cells ; Embryoid bodies
- C12N5/0606—Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/54—Ovaries; Ova; Ovules; Embryos; Foetal cells; Germ cells
- A61K35/545—Embryonic stem cells; Pluripotent stem cells; Induced pluripotent stem cells; Uncharacterised stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/45—Artificially induced pluripotent stem cells
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Chemical & Material Sciences (AREA)
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- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Zoology (AREA)
- Developmental Biology & Embryology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Reproductive Health (AREA)
- Ophthalmology & Optometry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gynecology & Obstetrics (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Immunology (AREA)
- Epidemiology (AREA)
- Virology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261624701P | 2012-04-16 | 2012-04-16 | |
| US61/624,701 | 2012-04-16 | ||
| PCT/US2013/030733 WO2013158258A1 (en) | 2012-04-16 | 2013-03-13 | Ocular therapeutics using embryonic system cell microvesicles |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015514760A true JP2015514760A (ja) | 2015-05-21 |
| JP2015514760A5 JP2015514760A5 (https=) | 2016-06-16 |
Family
ID=49383920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015506995A Pending JP2015514760A (ja) | 2012-04-16 | 2013-03-13 | 胚性幹細胞微小胞を用いる眼科治療法 |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20150079047A1 (https=) |
| EP (1) | EP2838995A4 (https=) |
| JP (1) | JP2015514760A (https=) |
| KR (1) | KR20150009541A (https=) |
| AU (1) | AU2013249786A1 (https=) |
| CA (1) | CA2870466A1 (https=) |
| IL (1) | IL235126A0 (https=) |
| WO (1) | WO2013158258A1 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7007770B1 (ja) | 2021-06-21 | 2022-02-10 | パナジー株式会社 | 眼症状改善剤および眼症状の改善方法 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101334404B1 (ko) * | 2011-04-28 | 2013-12-12 | 포항공과대학교 산학협력단 | 배아줄기세포 유래의 인공 마이크로베시클을 이용한 역분화 유도만능줄기세포의 제조방법 |
| CN109890964A (zh) * | 2016-09-09 | 2019-06-14 | 康奈尔大学 | 核酸、蛋白和小分子在玻璃体囊泡体中的递送 |
| US11653636B2 (en) * | 2019-11-15 | 2023-05-23 | University Of Ulsan Foundation For Industry Cooperation | Method of making a rat model of retinal degeneration and rat model made thereby |
| KR20230129828A (ko) | 2022-03-02 | 2023-09-11 | 포항공과대학교 산학협력단 | 안구 후방 질환 또는 손상의 예방 또는 치료용 조성물 |
Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004045666A1 (ja) * | 2002-11-15 | 2004-06-03 | Kyushu Tlo Company, Limited. | 臓器の再生方法 |
| JP2008536804A (ja) * | 2005-02-24 | 2008-09-11 | ザ・スクリプス・リサーチ・インステイチユート | 未熟児網膜症及び関連網膜症疾患の治療のための方法 |
| JP2009507770A (ja) * | 2005-07-27 | 2009-02-26 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド | 眼性疾患の治療への、熱ショックの使用 |
| JP2009528834A (ja) * | 2006-03-07 | 2009-08-13 | ギータ シュロフ | ヒト胚性幹細胞およびそれらの誘導体を含む組成物、使用方法、ならびに調製方法 |
| JP2010285434A (ja) * | 2002-07-25 | 2010-12-24 | Scripps Research Inst | 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法 |
| JP2011502142A (ja) * | 2007-10-29 | 2011-01-20 | フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 損傷しまたは傷害を受けた組織または臓器の内皮/上皮再生用医薬の製造のための、幹細胞由来微小胞(mv)の使用ならびにインビトロおよびインビボでの関連した方法 |
| WO2012020307A2 (en) * | 2010-08-13 | 2012-02-16 | The University Court Of The University Of Glasgow | Therapeutic uses of microvesicles and related micrornas |
| JP2014524437A (ja) * | 2011-08-16 | 2014-09-22 | サムスン ライフ パブリック ウェルフェア ファンデーション | 幹細胞由来微小胞を含む神経生成促進用組成物 |
| JP2015520174A (ja) * | 2012-05-31 | 2015-07-16 | ネオステム,インコーポレイティド | 眼疾患を治療するためのヒト極小胚様(vsel)幹細胞 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5824685A (en) * | 1995-02-01 | 1998-10-20 | The Johns Hopkins University School Of Medicine | Method of preventing proliferation of retinal pigment epithelium by retinoic acid receptor agonists |
| CA2711218C (en) * | 2008-01-04 | 2019-08-06 | Lydac Neuroscience Limited | A method of producing a population of differentiated cells |
| KR101268741B1 (ko) * | 2009-10-06 | 2013-06-04 | 김지연 | 줄기세포를 망막세포로 분화시키는 방법 |
-
2013
- 2013-03-13 AU AU2013249786A patent/AU2013249786A1/en not_active Abandoned
- 2013-03-13 WO PCT/US2013/030733 patent/WO2013158258A1/en not_active Ceased
- 2013-03-13 KR KR1020147031795A patent/KR20150009541A/ko not_active Withdrawn
- 2013-03-13 JP JP2015506995A patent/JP2015514760A/ja active Pending
- 2013-03-13 CA CA2870466A patent/CA2870466A1/en not_active Abandoned
- 2013-03-13 EP EP13778372.6A patent/EP2838995A4/en not_active Withdrawn
- 2013-03-13 US US14/394,688 patent/US20150079047A1/en not_active Abandoned
-
2014
- 2014-10-19 IL IL235126A patent/IL235126A0/en unknown
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2010285434A (ja) * | 2002-07-25 | 2010-12-24 | Scripps Research Inst | 造血幹細胞及び該細胞を使用して眼の新生血管の疾患を治療する方法 |
| WO2004045666A1 (ja) * | 2002-11-15 | 2004-06-03 | Kyushu Tlo Company, Limited. | 臓器の再生方法 |
| JP2008536804A (ja) * | 2005-02-24 | 2008-09-11 | ザ・スクリプス・リサーチ・インステイチユート | 未熟児網膜症及び関連網膜症疾患の治療のための方法 |
| JP2009507770A (ja) * | 2005-07-27 | 2009-02-26 | ユニバーシティ オブ フロリダ リサーチ ファウンデーション,インコーポレイティド | 眼性疾患の治療への、熱ショックの使用 |
| JP2009528834A (ja) * | 2006-03-07 | 2009-08-13 | ギータ シュロフ | ヒト胚性幹細胞およびそれらの誘導体を含む組成物、使用方法、ならびに調製方法 |
| JP2011502142A (ja) * | 2007-10-29 | 2011-01-20 | フレゼニウス メディカル ケア ドイッチェランド ゲゼルシャフト ミット ベシュレンクテル ハフツング | 損傷しまたは傷害を受けた組織または臓器の内皮/上皮再生用医薬の製造のための、幹細胞由来微小胞(mv)の使用ならびにインビトロおよびインビボでの関連した方法 |
| WO2012020307A2 (en) * | 2010-08-13 | 2012-02-16 | The University Court Of The University Of Glasgow | Therapeutic uses of microvesicles and related micrornas |
| JP2014524437A (ja) * | 2011-08-16 | 2014-09-22 | サムスン ライフ パブリック ウェルフェア ファンデーション | 幹細胞由来微小胞を含む神経生成促進用組成物 |
| JP2015520174A (ja) * | 2012-05-31 | 2015-07-16 | ネオステム,インコーポレイティド | 眼疾患を治療するためのヒト極小胚様(vsel)幹細胞 |
Non-Patent Citations (3)
| Title |
|---|
| EXPERIMENTAL HEMATOLOGY, vol. 32,7,Suppl.1, JPN6016049510, 2004, pages 57 - 58, ISSN: 0003467351 * |
| PLOS ONE, vol. 7(11), JPN6016049514, November 2012 (2012-11-01), pages 50417, ISSN: 0003467353 * |
| PROC.AMER.ASSOC.CANCER RES., vol. 45, JPN6016049512, 2004, pages 644 - 2792, ISSN: 0003467352 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP7007770B1 (ja) | 2021-06-21 | 2022-02-10 | パナジー株式会社 | 眼症状改善剤および眼症状の改善方法 |
| WO2022269973A1 (ja) * | 2021-06-21 | 2022-12-29 | パナジー株式会社 | 眼症状改善剤および眼症状の改善方法 |
| JP2023001664A (ja) * | 2021-06-21 | 2023-01-06 | パナジー株式会社 | 眼症状改善剤および眼症状の改善方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| EP2838995A4 (en) | 2016-01-06 |
| WO2013158258A8 (en) | 2014-09-04 |
| KR20150009541A (ko) | 2015-01-26 |
| WO2013158258A1 (en) | 2013-10-24 |
| CA2870466A1 (en) | 2013-10-24 |
| US20150079047A1 (en) | 2015-03-19 |
| EP2838995A1 (en) | 2015-02-25 |
| AU2013249786A1 (en) | 2014-11-06 |
| IL235126A0 (en) | 2014-12-31 |
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