AU2013249786A1 - Ocular therapeutics using embryonic stem cell microvesicles - Google Patents
Ocular therapeutics using embryonic stem cell microvesicles Download PDFInfo
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0618—Cells of the nervous system
- C12N5/0622—Glial cells, e.g. astrocytes, oligodendrocytes; Schwann cells
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/02—Coculture with; Conditioned medium produced by embryonic cells
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- C12N2502/00—Coculture with; Conditioned medium produced by
- C12N2502/45—Artificially induced pluripotent stem cells
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201261624701P | 2012-04-16 | 2012-04-16 | |
| US61/624,701 | 2012-04-16 | ||
| PCT/US2013/030733 WO2013158258A1 (en) | 2012-04-16 | 2013-03-13 | Ocular therapeutics using embryonic system cell microvesicles |
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| EP (1) | EP2838995A4 (https=) |
| JP (1) | JP2015514760A (https=) |
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| AU (1) | AU2013249786A1 (https=) |
| CA (1) | CA2870466A1 (https=) |
| IL (1) | IL235126A0 (https=) |
| WO (1) | WO2013158258A1 (https=) |
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| KR101334404B1 (ko) * | 2011-04-28 | 2013-12-12 | 포항공과대학교 산학협력단 | 배아줄기세포 유래의 인공 마이크로베시클을 이용한 역분화 유도만능줄기세포의 제조방법 |
| CN109890964A (zh) * | 2016-09-09 | 2019-06-14 | 康奈尔大学 | 核酸、蛋白和小分子在玻璃体囊泡体中的递送 |
| US11653636B2 (en) * | 2019-11-15 | 2023-05-23 | University Of Ulsan Foundation For Industry Cooperation | Method of making a rat model of retinal degeneration and rat model made thereby |
| JP7007770B1 (ja) * | 2021-06-21 | 2022-02-10 | パナジー株式会社 | 眼症状改善剤および眼症状の改善方法 |
| KR20230129828A (ko) | 2022-03-02 | 2023-09-11 | 포항공과대학교 산학협력단 | 안구 후방 질환 또는 손상의 예방 또는 치료용 조성물 |
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| US5824685A (en) * | 1995-02-01 | 1998-10-20 | The Johns Hopkins University School Of Medicine | Method of preventing proliferation of retinal pigment epithelium by retinoic acid receptor agonists |
| PL216193B1 (pl) * | 2002-07-25 | 2014-03-31 | Scripps Research Inst | Wyizolowana, ssacza, pochodząca ze szpiku kostnego linia populacji niezróżnicowanych krwiotwórczych komórek macierzystych |
| AU2003280824A1 (en) * | 2002-11-15 | 2004-06-15 | Fumihiko Ishikawa | Method of organ regeneration |
| AU2006216473B2 (en) * | 2005-02-24 | 2012-07-26 | The Scripps Research Institute | Method for the treatment of retinopathy of prematurity and related retinopathic diseases |
| KR20080031474A (ko) * | 2005-07-27 | 2008-04-08 | 유니버시티 오브 플로리다 리서치 파운데이션, 아이엔씨. | 안구 질환의 치료를 위한 열충격의 사용 |
| EP2422802A3 (en) * | 2006-03-07 | 2013-03-06 | Geeta Shroff | Compositions comprising human embryonic stem cells and their derivatives, methods of use, and methods of preparation |
| ES2523098T3 (es) * | 2007-10-29 | 2014-11-20 | Fresenius Medical Care Deutschland Gmbh | Microvesícula (MV) derivada de células madre para su uso en la inhibición de la apoptosis inducida por un agente citostático |
| CA2711218C (en) * | 2008-01-04 | 2019-08-06 | Lydac Neuroscience Limited | A method of producing a population of differentiated cells |
| KR101268741B1 (ko) * | 2009-10-06 | 2013-06-04 | 김지연 | 줄기세포를 망막세포로 분화시키는 방법 |
| CA2845280A1 (en) * | 2010-08-13 | 2012-02-16 | Paul Shiels | Therapeutic uses of microvesicles and related micrornas |
| WO2013025042A2 (ko) * | 2011-08-16 | 2013-02-21 | 사회복지법인 삼성생명공익재단 | 줄기세포 유래 미세소포를 포함하는 신경 생성 촉진용 조성물 |
| EP2866816A4 (en) * | 2012-05-31 | 2016-03-16 | Caladrius Biosciences Inc | VERY SMALL HUMAN EMBRYONIC STEM CELLS FOR THE TREATMENT OF EYE DISEASES |
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- 2013-03-13 US US14/394,688 patent/US20150079047A1/en not_active Abandoned
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2014
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Also Published As
| Publication number | Publication date |
|---|---|
| JP2015514760A (ja) | 2015-05-21 |
| EP2838995A4 (en) | 2016-01-06 |
| WO2013158258A8 (en) | 2014-09-04 |
| KR20150009541A (ko) | 2015-01-26 |
| WO2013158258A1 (en) | 2013-10-24 |
| CA2870466A1 (en) | 2013-10-24 |
| US20150079047A1 (en) | 2015-03-19 |
| EP2838995A1 (en) | 2015-02-25 |
| IL235126A0 (en) | 2014-12-31 |
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