JP2015514093A - 敗血症の処置のためのチモシンαの使用 - Google Patents

敗血症の処置のためのチモシンαの使用 Download PDF

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Publication number
JP2015514093A
JP2015514093A JP2015503582A JP2015503582A JP2015514093A JP 2015514093 A JP2015514093 A JP 2015514093A JP 2015503582 A JP2015503582 A JP 2015503582A JP 2015503582 A JP2015503582 A JP 2015503582A JP 2015514093 A JP2015514093 A JP 2015514093A
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JP
Japan
Prior art keywords
sepsis
thymosin alpha
days
administered
alpha peptide
Prior art date
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Pending
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JP2015503582A
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English (en)
Japanese (ja)
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JP2015514093A5 (enExample
Inventor
シンシア タシル
シンシア タシル
シャンドン クワン
シャンドン クワン
チャンフェン ウー
チャンフェン ウー
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Sciclone Pharmaceuticals LLC
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Sciclone Pharmaceuticals LLC
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Application filed by Sciclone Pharmaceuticals LLC filed Critical Sciclone Pharmaceuticals LLC
Publication of JP2015514093A publication Critical patent/JP2015514093A/ja
Publication of JP2015514093A5 publication Critical patent/JP2015514093A5/ja
Pending legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/2292—Thymosin; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2015503582A 2012-03-30 2013-03-28 敗血症の処置のためのチモシンαの使用 Pending JP2015514093A (ja)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US201261618563P 2012-03-30 2012-03-30
US61/618,563 2012-03-30
US201261643824P 2012-05-07 2012-05-07
US61/643,824 2012-05-07
US13/835,107 US20130296223A1 (en) 2012-03-30 2013-03-15 Use of thymosin alpha for the treatment of sepsis
US13/835,107 2013-03-15
PCT/US2013/034394 WO2013149030A2 (en) 2012-03-30 2013-03-28 Use of thymosin alpha for the treatment of sepsis

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017108931A Division JP2017214377A (ja) 2012-03-30 2017-06-01 敗血症の処置のためのチモシンαの使用

Publications (2)

Publication Number Publication Date
JP2015514093A true JP2015514093A (ja) 2015-05-18
JP2015514093A5 JP2015514093A5 (enExample) 2015-12-17

Family

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Family Applications (6)

Application Number Title Priority Date Filing Date
JP2015503582A Pending JP2015514093A (ja) 2012-03-30 2013-03-28 敗血症の処置のためのチモシンαの使用
JP2017108931A Pending JP2017214377A (ja) 2012-03-30 2017-06-01 敗血症の処置のためのチモシンαの使用
JP2019120721A Pending JP2019156854A (ja) 2012-03-30 2019-06-28 敗血症の処置のためのチモシンαの使用
JP2021065044A Pending JP2021100983A (ja) 2012-03-30 2021-04-07 敗血症の処置のためのチモシンαの使用
JP2022161403A Pending JP2022176345A (ja) 2012-03-30 2022-10-06 敗血症の処置のためのチモシンαの使用
JP2025076491A Pending JP2025107346A (ja) 2012-03-30 2025-05-02 敗血症の処置のためのチモシンαの使用

Family Applications After (5)

Application Number Title Priority Date Filing Date
JP2017108931A Pending JP2017214377A (ja) 2012-03-30 2017-06-01 敗血症の処置のためのチモシンαの使用
JP2019120721A Pending JP2019156854A (ja) 2012-03-30 2019-06-28 敗血症の処置のためのチモシンαの使用
JP2021065044A Pending JP2021100983A (ja) 2012-03-30 2021-04-07 敗血症の処置のためのチモシンαの使用
JP2022161403A Pending JP2022176345A (ja) 2012-03-30 2022-10-06 敗血症の処置のためのチモシンαの使用
JP2025076491A Pending JP2025107346A (ja) 2012-03-30 2025-05-02 敗血症の処置のためのチモシンαの使用

Country Status (8)

Country Link
US (5) US20130296223A1 (enExample)
EP (2) EP2841088B1 (enExample)
JP (6) JP2015514093A (enExample)
KR (1) KR20150048663A (enExample)
CN (2) CN107519483A (enExample)
CA (1) CA2866435A1 (enExample)
HK (1) HK1246694A1 (enExample)
WO (1) WO2013149030A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019207684A (ja) * 2018-04-10 2019-12-05 ヒル−ロム サービシズ，インコーポレイテッド 医療施設の複数のソースからのデータに基づく患者リスク評価

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017524943A (ja) * 2014-08-12 2017-08-31 アルサニス・バイオサイエンスズ・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング Ｓ．アウレウス疾患の予測
WO2019028448A1 (en) * 2017-08-04 2019-02-07 The Johns Hopkins University APPLICATION FOR EARLY PREDICTION OF SEPTIC SHOCK WAITING
SMT202400412T1 (it) * 2018-04-20 2024-11-15 Combioxin Sa Trattamento dell'ipotensione con sepsi o shock settico
WO2023285349A1 (en) 2021-07-12 2023-01-19 2N Pharma Aps Carnitine-palmitoyl-transferase-1 (cpt-1) inhibitors for use in a method of preventing or treating sepsis in a mammalian subject

Citations (5)

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WO1995009647A1 (en) * 1993-10-07 1995-04-13 The George Washington University Medical Center METHOD OF TREATING SEPTIC SHOCK USING THYMOSIN-α¿1?
JP2002500189A (ja) * 1998-01-08 2002-01-08 エド・ガイストリヒ・ゼーネ・アクチエンゲゼルシャフト・フューア・ヒェーミシェ・インドゥストリー 微生物の院内感染症の治療用医薬の製造におけるタウロリジンまたはタウラルタムのような抗微生物薬剤の使用
CN101020048A (zh) * 2007-02-12 2007-08-22 广东天普生化医药股份有限公司 一种用于治疗脓毒症的药物组合物
JP2010522192A (ja) * 2007-03-21 2010-07-01 ボーシュ アンド ローム インコーポレイティド 抗菌薬耐性のバクテリアによって引き起こされる感染症を治療、軽減、寛解、又は予防するための組成物及び方法
WO2011104352A1 (en) * 2010-02-25 2011-09-01 Agennix Ag Oral lactoferrin in the treatment of severe sepsis

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US4079127A (en) 1976-10-28 1978-03-14 Board Of Regents Of The University Of Texas Thymosin alpha 1
TW252045B (enExample) * 1993-10-07 1995-07-21 Allan L Goldstein
UA80957C2 (en) 2001-11-01 2007-11-26 Sciclone Pharmaceuticals Inc Method of administering a thymosin alpha 1 peptide
US7897567B2 (en) * 2002-11-25 2011-03-01 Sciclone Pharmaceuticals, Inc. Methods of protecting against radiation damage using alpha thymosin
US9205050B2 (en) * 2005-09-29 2015-12-08 Bayer Intellectual Property Gmbh Antibiotic formulations, unit doses, kits and methods
JP2011506436A (ja) * 2007-12-12 2011-03-03 サイクローン・ファーマシューティカルズ・インコーポレイテッド 細胞傷害性ｔリンパ球抗原４（ｃｔｌａ４）に対する抗体と組み合わせられたアルファチモシンペプチドによる黒色腫の処置の方法
CN101514228A (zh) * 2008-02-21 2009-08-26 张卓兵 N-端修饰的人胸腺肽α1复合物及其制备方法
ES2537785T3 (es) * 2009-05-08 2015-06-12 Sciclone Pharmaceuticals, Inc. Péptidos de alfa timosina como potenciadores de vacunas
CN103458681A (zh) * 2011-02-09 2013-12-18 赛生制药有限公司 用于预防感染、降低感染的严重性、及治疗感染的胸腺素α肽

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995009647A1 (en) * 1993-10-07 1995-04-13 The George Washington University Medical Center METHOD OF TREATING SEPTIC SHOCK USING THYMOSIN-α¿1?
JP2002500189A (ja) * 1998-01-08 2002-01-08 エド・ガイストリヒ・ゼーネ・アクチエンゲゼルシャフト・フューア・ヒェーミシェ・インドゥストリー 微生物の院内感染症の治療用医薬の製造におけるタウロリジンまたはタウラルタムのような抗微生物薬剤の使用
CN101020048A (zh) * 2007-02-12 2007-08-22 广东天普生化医药股份有限公司 一种用于治疗脓毒症的药物组合物
JP2010522192A (ja) * 2007-03-21 2010-07-01 ボーシュ アンド ローム インコーポレイティド 抗菌薬耐性のバクテリアによって引き起こされる感染症を治療、軽減、寛解、又は予防するための組成物及び方法
WO2011104352A1 (en) * 2010-02-25 2011-09-01 Agennix Ag Oral lactoferrin in the treatment of severe sepsis

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CHIN. CRIT. CARE MED. 2009, VOL.21, NO.1, P.21-24, JPN6016027709, ISSN: 0003362425 *
CHIN. CRIT. CARE MED., 2007, VOL.19, NO.3, P.153-155, JPN6016027716, ISSN: 0003362426 *
CHIN. CRIT. CARE MED., 2009, VOL.21, NO.3, P.147-150, JPN6016027712, ISSN: 0003362427 *
THE JOURNAL OF INFECTIOUS DISEASES, 2008, VOL.198, P.723-730, JPN6016027714, ISSN: 0003362428 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2019207684A (ja) * 2018-04-10 2019-12-05 ヒル−ロム サービシズ，インコーポレイテッド 医療施設の複数のソースからのデータに基づく患者リスク評価
JP2020129396A (ja) * 2018-04-10 2020-08-27 ヒル−ロム サービシズ，インコーポレイテッド 医療施設の複数のソースからのデータに基づく患者リスク評価

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CA2866435A1 (en) 2013-10-03
JP2025107346A (ja) 2025-07-17
JP2017214377A (ja) 2017-12-07
JP2019156854A (ja) 2019-09-19
WO2013149030A2 (en) 2013-10-03
KR20150048663A (ko) 2015-05-07
US20240091314A1 (en) 2024-03-21
JP2021100983A (ja) 2021-07-08
HK1246694A1 (zh) 2018-09-14
JP2022176345A (ja) 2022-11-25
EP2841088A4 (en) 2015-10-14
CN105338996A (zh) 2016-02-17
CN107519483A (zh) 2017-12-29
US20150024994A1 (en) 2015-01-22
US20180236036A1 (en) 2018-08-23
HK1207314A1 (en) 2016-01-29
EP3741386A1 (en) 2020-11-25
EP2841088B1 (en) 2020-06-17
US20210106656A1 (en) 2021-04-15
EP2841088A2 (en) 2015-03-04
US20130296223A1 (en) 2013-11-07

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