CN107519483A - α胸腺肽用于脓毒症治疗的用途 - Google Patents
α胸腺肽用于脓毒症治疗的用途 Download PDFInfo
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- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 description 1
- LPQZKKCYTLCDGQ-WEDXCCLWSA-N tazobactam Chemical compound C([C@]1(C)S([C@H]2N(C(C2)=O)[C@H]1C(O)=O)(=O)=O)N1C=CN=N1 LPQZKKCYTLCDGQ-WEDXCCLWSA-N 0.000 description 1
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/2292—Thymosin; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| US201261618563P | 2012-03-30 | 2012-03-30 | |
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| US201261643824P | 2012-05-07 | 2012-05-07 | |
| US61/643824 | 2012-05-07 | ||
| US13/835,107 US20130296223A1 (en) | 2012-03-30 | 2013-03-15 | Use of thymosin alpha for the treatment of sepsis |
| US13/835107 | 2013-03-15 | ||
| CN201380028974.4A CN105338996A (zh) | 2012-03-30 | 2013-03-28 | α胸腺肽用于脓毒症治疗的用途 |
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| CN201380028974.4A Division CN105338996A (zh) | 2012-03-30 | 2013-03-28 | α胸腺肽用于脓毒症治疗的用途 |
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| CN107519483A true CN107519483A (zh) | 2017-12-29 |
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| CN201380028974.4A Pending CN105338996A (zh) | 2012-03-30 | 2013-03-28 | α胸腺肽用于脓毒症治疗的用途 |
| CN201710735183.5A Pending CN107519483A (zh) | 2012-03-30 | 2013-03-28 | α胸腺肽用于脓毒症治疗的用途 |
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| CN201380028974.4A Pending CN105338996A (zh) | 2012-03-30 | 2013-03-28 | α胸腺肽用于脓毒症治疗的用途 |
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| Country | Link |
|---|---|
| US (5) | US20130296223A1 (enExample) |
| EP (2) | EP3741386A1 (enExample) |
| JP (6) | JP2015514093A (enExample) |
| KR (1) | KR20150048663A (enExample) |
| CN (2) | CN105338996A (enExample) |
| CA (1) | CA2866435A1 (enExample) |
| HK (1) | HK1246694A1 (enExample) |
| WO (1) | WO2013149030A2 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111971068A (zh) * | 2018-04-20 | 2020-11-20 | 康柏辛股份有限公司 | 败血症和败血性休克的治疗 |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2015303147A1 (en) * | 2014-08-12 | 2017-02-23 | Arsanis Biosciences Gmbh | Predicting S. aureus disease |
| WO2019028448A1 (en) * | 2017-08-04 | 2019-02-07 | The Johns Hopkins University | APPLICATION FOR EARLY PREDICTION OF SEPTIC SHOCK WAITING |
| US11504071B2 (en) * | 2018-04-10 | 2022-11-22 | Hill-Rom Services, Inc. | Patient risk assessment based on data from multiple sources in a healthcare facility |
| EP4370129A1 (en) | 2021-07-12 | 2024-05-22 | 2N Pharma ApS | Carnitine-palmitoyl-transferase-1 (cpt-1) inhibitors for use in a method of preventing or treating sepsis in a mammalian subject |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101020048A (zh) * | 2007-02-12 | 2007-08-22 | 广东天普生化医药股份有限公司 | 一种用于治疗脓毒症的药物组合物 |
| CN101514228A (zh) * | 2008-02-21 | 2009-08-26 | 张卓兵 | N-端修饰的人胸腺肽α1复合物及其制备方法 |
| WO2010129947A2 (en) * | 2009-05-08 | 2010-11-11 | Sciclone Pharmaceuticals, Inc. | Alpha thymosin peptides as vaccine enhancers |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4079127A (en) | 1976-10-28 | 1978-03-14 | Board Of Regents Of The University Of Texas | Thymosin alpha 1 |
| WO1995009647A1 (en) * | 1993-10-07 | 1995-04-13 | The George Washington University Medical Center | METHOD OF TREATING SEPTIC SHOCK USING THYMOSIN-α¿1? |
| TW252045B (enExample) * | 1993-10-07 | 1995-07-21 | Allan L Goldstein | |
| US5972933A (en) * | 1998-01-08 | 1999-10-26 | Ed. Geistlich Sohne Ag Fur Chemische Industrie | Method of treating microbial infections |
| UA80957C2 (en) | 2001-11-01 | 2007-11-26 | Sciclone Pharmaceuticals Inc | Method of administering a thymosin alpha 1 peptide |
| UA81932C2 (uk) * | 2002-11-25 | 2008-02-25 | Сайклон Фармасютикалс, Инк | СПОСІБ ЗАХИСТУ ВІД РАДІАЦІЙНОГО УРАЖЕННЯ ІЗ ЗАСТОСУВАННЯМ α-ТИМОЗИНУ |
| EP1928410A2 (en) * | 2005-09-29 | 2008-06-11 | Nektar Therapeutics | Antibiotic formulations, unit doses, kits, and methods |
| WO2008115951A1 (en) * | 2007-03-21 | 2008-09-25 | Bausch & Lomb Incorporated | Fluoroquinolones for treating, reducing, ameliorating, or preventing infections caused by antibacterial drug-resistant bacteria |
| AU2008335840A1 (en) * | 2007-12-12 | 2009-06-18 | Sciclone Pharmaceuticals, Inc. | Treatment of melanoma with alpha thymosin peptides in combination with antibodies against cytotoxic T lymphocyte-associated antigen 4 (CTLA4) |
| WO2011104352A1 (en) * | 2010-02-25 | 2011-09-01 | Agennix Ag | Oral lactoferrin in the treatment of severe sepsis |
| CA2826875A1 (en) * | 2011-02-09 | 2012-08-16 | Sciclone Pharmaceuticals, Inc. | Thymosin alpha peptide for preventing, reducing the severity of, and treating infection |
-
2013
- 2013-03-15 US US13/835,107 patent/US20130296223A1/en not_active Abandoned
- 2013-03-28 US US13/877,323 patent/US20150024994A1/en not_active Abandoned
- 2013-03-28 KR KR1020147027456A patent/KR20150048663A/ko not_active Ceased
- 2013-03-28 CN CN201380028974.4A patent/CN105338996A/zh active Pending
- 2013-03-28 CN CN201710735183.5A patent/CN107519483A/zh active Pending
- 2013-03-28 EP EP20180095.0A patent/EP3741386A1/en active Pending
- 2013-03-28 EP EP13768168.0A patent/EP2841088B1/en active Active
- 2013-03-28 CA CA2866435A patent/CA2866435A1/en active Pending
- 2013-03-28 JP JP2015503582A patent/JP2015514093A/ja active Pending
- 2013-03-28 WO PCT/US2013/034394 patent/WO2013149030A2/en not_active Ceased
-
2017
- 2017-06-01 JP JP2017108931A patent/JP2017214377A/ja active Pending
- 2017-09-20 US US15/710,012 patent/US20180236036A1/en not_active Abandoned
-
2018
- 2018-05-18 HK HK18106506.4A patent/HK1246694A1/zh unknown
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2019
- 2019-06-28 JP JP2019120721A patent/JP2019156854A/ja active Pending
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2020
- 2020-05-22 US US16/881,314 patent/US20210106656A1/en not_active Abandoned
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2021
- 2021-04-07 JP JP2021065044A patent/JP2021100983A/ja active Pending
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2022
- 2022-10-06 JP JP2022161403A patent/JP2022176345A/ja active Pending
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2023
- 2023-09-13 US US18/466,693 patent/US20240091314A1/en not_active Abandoned
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2025
- 2025-05-02 JP JP2025076491A patent/JP2025107346A/ja active Pending
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| CN101020048A (zh) * | 2007-02-12 | 2007-08-22 | 广东天普生化医药股份有限公司 | 一种用于治疗脓毒症的药物组合物 |
| CN101514228A (zh) * | 2008-02-21 | 2009-08-26 | 张卓兵 | N-端修饰的人胸腺肽α1复合物及其制备方法 |
| WO2010129947A2 (en) * | 2009-05-08 | 2010-11-11 | Sciclone Pharmaceuticals, Inc. | Alpha thymosin peptides as vaccine enhancers |
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| 梅徽，郭皖北: "胸腺肽α1对脓毒性休克患者的临床疗效及增强免疫功能的研究", 《湘南学院学报（医学版）》 * |
| 黄顺伟等: "创伤性严重脓毒症和多器官功能障碍综合征免疫调理治疗的临床研究和远期评价", 《中国危重病急救医学》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111971068A (zh) * | 2018-04-20 | 2020-11-20 | 康柏辛股份有限公司 | 败血症和败血性休克的治疗 |
Also Published As
| Publication number | Publication date |
|---|---|
| JP2015514093A (ja) | 2015-05-18 |
| EP3741386A1 (en) | 2020-11-25 |
| JP2017214377A (ja) | 2017-12-07 |
| HK1207314A1 (en) | 2016-01-29 |
| WO2013149030A2 (en) | 2013-10-03 |
| US20210106656A1 (en) | 2021-04-15 |
| US20240091314A1 (en) | 2024-03-21 |
| EP2841088A4 (en) | 2015-10-14 |
| CA2866435A1 (en) | 2013-10-03 |
| US20180236036A1 (en) | 2018-08-23 |
| US20150024994A1 (en) | 2015-01-22 |
| JP2022176345A (ja) | 2022-11-25 |
| US20130296223A1 (en) | 2013-11-07 |
| EP2841088A2 (en) | 2015-03-04 |
| EP2841088B1 (en) | 2020-06-17 |
| HK1246694A1 (zh) | 2018-09-14 |
| JP2021100983A (ja) | 2021-07-08 |
| JP2025107346A (ja) | 2025-07-17 |
| JP2019156854A (ja) | 2019-09-19 |
| CN105338996A (zh) | 2016-02-17 |
| KR20150048663A (ko) | 2015-05-07 |
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