JP2015511623A5 - - Google Patents
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- Publication number
- JP2015511623A5 JP2015511623A5 JP2015502436A JP2015502436A JP2015511623A5 JP 2015511623 A5 JP2015511623 A5 JP 2015511623A5 JP 2015502436 A JP2015502436 A JP 2015502436A JP 2015502436 A JP2015502436 A JP 2015502436A JP 2015511623 A5 JP2015511623 A5 JP 2015511623A5
- Authority
- JP
- Japan
- Prior art keywords
- particles
- suspension
- membrane
- membrane separation
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000002245 particle Substances 0.000 claims 37
- 238000000034 method Methods 0.000 claims 31
- 239000012528 membrane Substances 0.000 claims 24
- 238000000926 separation method Methods 0.000 claims 20
- 239000000725 suspension Substances 0.000 claims 18
- 239000000203 mixture Substances 0.000 claims 16
- 238000005374 membrane filtration Methods 0.000 claims 10
- 239000012466 permeate Substances 0.000 claims 10
- 239000002904 solvent Substances 0.000 claims 10
- 238000004064 recycling Methods 0.000 claims 7
- 229940126534 drug product Drugs 0.000 claims 6
- 239000000825 pharmaceutical preparation Substances 0.000 claims 6
- 239000008186 active pharmaceutical agent Substances 0.000 claims 5
- 238000009826 distribution Methods 0.000 claims 5
- 238000005549 size reduction Methods 0.000 claims 4
- 238000000227 grinding Methods 0.000 claims 3
- 239000000543 intermediate Substances 0.000 claims 3
- 239000000546 pharmaceutical excipient Substances 0.000 claims 3
- 229920000642 polymer Polymers 0.000 claims 3
- 239000012465 retentate Substances 0.000 claims 3
- 239000003814 drug Substances 0.000 claims 2
- 229940079593 drug Drugs 0.000 claims 2
- 239000012510 hollow fiber Substances 0.000 claims 2
- 238000000265 homogenisation Methods 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 238000005119 centrifugation Methods 0.000 claims 1
- 229940088679 drug related substance Drugs 0.000 claims 1
- 238000001914 filtration Methods 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 238000002955 isolation Methods 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 238000010951 particle size reduction Methods 0.000 claims 1
- 239000011148 porous material Substances 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000001694 spray drying Methods 0.000 claims 1
- 239000004094 surface-active agent Substances 0.000 claims 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PT106237 | 2012-03-30 | ||
| PT106237A PT106237B (pt) | 2012-03-30 | 2012-03-30 | Produção de partículas substancialmente monodispersas utilizando moagem e separação por membranas |
| PCT/GB2013/000146 WO2013144554A1 (en) | 2012-03-30 | 2013-03-28 | Production of near monodisperse particles using milling and membrane separation. |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015511623A JP2015511623A (ja) | 2015-04-20 |
| JP2015511623A5 true JP2015511623A5 (enExample) | 2016-03-03 |
| JP6247680B2 JP6247680B2 (ja) | 2017-12-13 |
Family
ID=48095912
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2015502436A Expired - Fee Related JP6247680B2 (ja) | 2012-03-30 | 2013-03-28 | 粉砕及び膜分離を使用する近単分散粒子の製造 |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US9937470B2 (enExample) |
| EP (1) | EP2830597B1 (enExample) |
| JP (1) | JP6247680B2 (enExample) |
| CN (2) | CN110314546A (enExample) |
| CA (1) | CA2868676C (enExample) |
| DK (1) | DK2830597T3 (enExample) |
| ES (1) | ES2660401T3 (enExample) |
| HU (1) | HUE037271T2 (enExample) |
| IL (1) | IL234918A0 (enExample) |
| PT (1) | PT106237B (enExample) |
| TW (1) | TWI572370B (enExample) |
| WO (1) | WO2013144554A1 (enExample) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8691145B2 (en) | 2009-11-16 | 2014-04-08 | Flodesign Sonics, Inc. | Ultrasound and acoustophoresis for water purification |
| US9783775B2 (en) | 2012-03-15 | 2017-10-10 | Flodesign Sonics, Inc. | Bioreactor using acoustic standing waves |
| US9752114B2 (en) | 2012-03-15 | 2017-09-05 | Flodesign Sonics, Inc | Bioreactor using acoustic standing waves |
| US10704021B2 (en) | 2012-03-15 | 2020-07-07 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9458450B2 (en) | 2012-03-15 | 2016-10-04 | Flodesign Sonics, Inc. | Acoustophoretic separation technology using multi-dimensional standing waves |
| US9796956B2 (en) | 2013-11-06 | 2017-10-24 | Flodesign Sonics, Inc. | Multi-stage acoustophoresis device |
| US9752113B2 (en) | 2012-03-15 | 2017-09-05 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9950282B2 (en) | 2012-03-15 | 2018-04-24 | Flodesign Sonics, Inc. | Electronic configuration and control for acoustic standing wave generation |
| US10689609B2 (en) | 2012-03-15 | 2020-06-23 | Flodesign Sonics, Inc. | Acoustic bioreactor processes |
| US9272234B2 (en) | 2012-03-15 | 2016-03-01 | Flodesign Sonics, Inc. | Separation of multi-component fluid through ultrasonic acoustophoresis |
| US10967298B2 (en) | 2012-03-15 | 2021-04-06 | Flodesign Sonics, Inc. | Driver and control for variable impedence load |
| US9745548B2 (en) | 2012-03-15 | 2017-08-29 | Flodesign Sonics, Inc. | Acoustic perfusion devices |
| US9567559B2 (en) | 2012-03-15 | 2017-02-14 | Flodesign Sonics, Inc. | Bioreactor using acoustic standing waves |
| US10322949B2 (en) | 2012-03-15 | 2019-06-18 | Flodesign Sonics, Inc. | Transducer and reflector configurations for an acoustophoretic device |
| US10370635B2 (en) | 2012-03-15 | 2019-08-06 | Flodesign Sonics, Inc. | Acoustic separation of T cells |
| US10953436B2 (en) | 2012-03-15 | 2021-03-23 | Flodesign Sonics, Inc. | Acoustophoretic device with piezoelectric transducer array |
| PT106237B (pt) | 2012-03-30 | 2015-03-19 | Hovione Farmaci Ncia S A | Produção de partículas substancialmente monodispersas utilizando moagem e separação por membranas |
| US10737953B2 (en) | 2012-04-20 | 2020-08-11 | Flodesign Sonics, Inc. | Acoustophoretic method for use in bioreactors |
| CA2909950A1 (en) * | 2013-04-25 | 2014-10-30 | Flodesign Sonics, Inc. | Excipient removal from pharmacological samples |
| US9745569B2 (en) | 2013-09-13 | 2017-08-29 | Flodesign Sonics, Inc. | System for generating high concentration factors for low cell density suspensions |
| CA2935960C (en) | 2014-01-08 | 2023-01-10 | Bart Lipkens | Acoustophoresis device with dual acoustophoretic chamber |
| PT107433B (pt) * | 2014-01-28 | 2018-12-04 | Hovione Farm S A | Processo de redução e controlo do tamanho de partícula |
| US9744483B2 (en) | 2014-07-02 | 2017-08-29 | Flodesign Sonics, Inc. | Large scale acoustic separation device |
| US10705070B1 (en) | 2015-03-05 | 2020-07-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and poorly water soluble drug |
| US10527604B1 (en) | 2015-03-05 | 2020-01-07 | Abraxis Bioscience, Llc | Methods of assessing suitability of use of pharmaceutical compositions of albumin and paclitaxel |
| US10106770B2 (en) | 2015-03-24 | 2018-10-23 | Flodesign Sonics, Inc. | Methods and apparatus for particle aggregation using acoustic standing waves |
| PT108368B (pt) | 2015-03-31 | 2018-11-05 | Hovione Farm S A | Produção contínua de partículas |
| US11377651B2 (en) | 2016-10-19 | 2022-07-05 | Flodesign Sonics, Inc. | Cell therapy processes utilizing acoustophoresis |
| US11708572B2 (en) | 2015-04-29 | 2023-07-25 | Flodesign Sonics, Inc. | Acoustic cell separation techniques and processes |
| US11021699B2 (en) | 2015-04-29 | 2021-06-01 | FioDesign Sonics, Inc. | Separation using angled acoustic waves |
| US11474085B2 (en) | 2015-07-28 | 2022-10-18 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| US11459540B2 (en) | 2015-07-28 | 2022-10-04 | Flodesign Sonics, Inc. | Expanded bed affinity selection |
| CH712233A2 (de) * | 2016-03-15 | 2017-09-15 | Arcolor Ag | Verfahren zur Herstellung von Dispersionen mit definierter Partikelgrösse. |
| US10710006B2 (en) | 2016-04-25 | 2020-07-14 | Flodesign Sonics, Inc. | Piezoelectric transducer for generation of an acoustic standing wave |
| CN114891635A (zh) | 2016-05-03 | 2022-08-12 | 弗洛设计声能学公司 | 利用声泳的治疗细胞洗涤、浓缩和分离 |
| US11085035B2 (en) | 2016-05-03 | 2021-08-10 | Flodesign Sonics, Inc. | Therapeutic cell washing, concentration, and separation utilizing acoustophoresis |
| US11214789B2 (en) | 2016-05-03 | 2022-01-04 | Flodesign Sonics, Inc. | Concentration and washing of particles with acoustics |
| CN110494543A (zh) | 2016-10-19 | 2019-11-22 | 弗洛设计声能学公司 | 通过声学的亲和细胞提取 |
| KR20220066413A (ko) | 2017-12-14 | 2022-05-24 | 프로디자인 소닉스, 인크. | 음향 트랜스듀서 구동기 및 제어기 |
| CN118515598A (zh) * | 2018-12-07 | 2024-08-20 | 斯塔蒂亚生物制药有限公司 | 甲异靛的多晶型和甲异靛的改进制剂 |
| US20220106554A1 (en) * | 2019-01-30 | 2022-04-07 | Repligen Corporation | Method of using track etched membranes for the filtration of biological fluids |
| US10569278B1 (en) * | 2019-10-02 | 2020-02-25 | Nanostar, Inc. | System for reducing oxygen contamination of milled silicon |
| EP4051241A4 (en) | 2019-10-28 | 2023-12-06 | Abraxis BioScience, LLC | PHARMACEUTICAL COMPOSITIONS OF ALBUMIN AND RAPAMYCIN |
| CN110773079B (zh) * | 2019-11-18 | 2022-03-01 | 江苏博迁新材料股份有限公司 | 一种超声喷雾法制备超细粉球的方法 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3977967A (en) * | 1973-05-10 | 1976-08-31 | Union Carbide Corporation | Ultrafiltration apparatus and process for the treatment of liquids |
| JPH1133362A (ja) * | 1997-07-23 | 1999-02-09 | Japan Organo Co Ltd | 研磨剤の回収方法及び研磨剤の回収装置 |
| US5879715A (en) * | 1997-09-02 | 1999-03-09 | Ceramem Corporation | Process and system for production of inorganic nanoparticles |
| CN1190454C (zh) | 2000-04-28 | 2005-02-23 | 田边制药株式会社 | 用于制备微球的方法 |
| CN1374253A (zh) * | 2002-04-12 | 2002-10-16 | 黄榕 | 从含杂质离子悬浮液中分离超细沉淀硫酸钡颗粒的方法 |
| US6962006B2 (en) | 2002-12-19 | 2005-11-08 | Acusphere, Inc. | Methods and apparatus for making particles using spray dryer and in-line jet mill |
| US20050258288A1 (en) | 2003-11-26 | 2005-11-24 | E. I. Du Pont De Nemours And Company | High pressure media milling system and process of forming particles |
| US20060008498A1 (en) | 2004-07-12 | 2006-01-12 | Chen Tzer-Fen D | Nano-particle production |
| US20060122049A1 (en) * | 2004-12-03 | 2006-06-08 | 3M Innovative Properties Company | Method of making glass microbubbles and raw product |
| EP1834624A4 (en) | 2005-01-07 | 2011-05-04 | Eisai R&D Man Co Ltd | MEDICAL COMPOSITION AND MANUFACTURING METHOD THEREFOR |
| US20100172994A1 (en) | 2006-11-22 | 2010-07-08 | University Of Florida Research Foundation, Inc. | Nanoparticles for Protection of Cells from Oxidative Stress |
| TWI405590B (zh) | 2007-04-06 | 2013-08-21 | Activus Pharma Co Ltd | 微粉碎化有機化合物粒子之製法 |
| DE102007054885A1 (de) * | 2007-11-15 | 2009-05-20 | Evonik Degussa Gmbh | Verfahren zur Fraktionierung oxidischer Nanopartikel durch Querstrom-Membranfiltration |
| FR2929136B1 (fr) | 2008-03-25 | 2011-11-11 | Sprainnov | Procede et tete de pulverisation, procede et tour associes pour fabriquer un produit pulverulent |
| PT105058B (pt) * | 2010-04-21 | 2013-04-17 | Hovione Farmaciencia S A | Processo para processamento de partículas de ingredientes activos farmacêuticos |
| PT106237B (pt) | 2012-03-30 | 2015-03-19 | Hovione Farmaci Ncia S A | Produção de partículas substancialmente monodispersas utilizando moagem e separação por membranas |
-
2012
- 2012-03-30 PT PT106237A patent/PT106237B/pt active IP Right Grant
-
2013
- 2013-03-28 JP JP2015502436A patent/JP6247680B2/ja not_active Expired - Fee Related
- 2013-03-28 CA CA2868676A patent/CA2868676C/en active Active
- 2013-03-28 DK DK13716344.0T patent/DK2830597T3/en active
- 2013-03-28 US US14/389,117 patent/US9937470B2/en active Active
- 2013-03-28 CN CN201910535128.0A patent/CN110314546A/zh active Pending
- 2013-03-28 WO PCT/GB2013/000146 patent/WO2013144554A1/en not_active Ceased
- 2013-03-28 HU HUE13716344A patent/HUE037271T2/hu unknown
- 2013-03-28 ES ES13716344.0T patent/ES2660401T3/es active Active
- 2013-03-28 CN CN201380022846.9A patent/CN104321050A/zh active Pending
- 2013-03-28 EP EP13716344.0A patent/EP2830597B1/en active Active
- 2013-03-29 TW TW102111579A patent/TWI572370B/zh not_active IP Right Cessation
-
2014
- 2014-09-30 IL IL234918A patent/IL234918A0/en unknown
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