JP2015511531A - 分子分離装置 - Google Patents

分子分離装置 Download PDF

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Publication number
JP2015511531A
JP2015511531A JP2015501867A JP2015501867A JP2015511531A JP 2015511531 A JP2015511531 A JP 2015511531A JP 2015501867 A JP2015501867 A JP 2015501867A JP 2015501867 A JP2015501867 A JP 2015501867A JP 2015511531 A JP2015511531 A JP 2015511531A
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Japan
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separation membrane
membrane
blocked
components
chamber
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JP2015501867A
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English (en)
Japanese (ja)
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ジョン、ビー．ステットソン、ジュニア
サラ、サイモン
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ロッキード・マーチン・コーポレーション
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/24—Extraction; Separation; Purification by electrochemical means
    • C07K1/26—Electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
    • B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
    • B01D35/06—Filters making use of electricity or magnetism
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/02—Inorganic material
    • B01D71/021—Carbon
    • B01D71/0211—Graphene or derivates thereof
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2325/00—Details relating to properties of membranes
    • B01D2325/20—Specific permeability or cut-off range
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
    • B01D61/14—Ultrafiltration; Microfiltration
    • B01D61/18—Apparatus therefor
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Electrochemistry (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Water Supply & Treatment (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Environmental & Geological Engineering (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Urology & Nephrology (AREA)
  • Electrostatic Separation (AREA)
  • Peptides Or Proteins (AREA)
JP2015501867A 2012-03-21 2013-03-20 分子分離装置 Pending JP2015511531A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261613578P 2012-03-21 2012-03-21
US61/613,578 2012-03-21
PCT/US2013/033035 WO2013142539A1 (en) 2012-03-21 2013-03-20 Molecular separation device

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2017002652A Division JP2017100127A (ja) 2012-03-21 2017-01-11 分子分離装置

Publications (1)

Publication Number Publication Date
JP2015511531A true JP2015511531A (ja) 2015-04-20

Family

ID=48050312

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2015501867A Pending JP2015511531A (ja) 2012-03-21 2013-03-20 分子分離装置
JP2017002652A Pending JP2017100127A (ja) 2012-03-21 2017-01-11 分子分離装置

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2017002652A Pending JP2017100127A (ja) 2012-03-21 2017-01-11 分子分離装置

Country Status (12)

Country Link
US (2) US9028663B2 (enExample)
EP (1) EP2827974A1 (enExample)
JP (2) JP2015511531A (enExample)
KR (1) KR20140147855A (enExample)
CN (2) CN106823846A (enExample)
AU (2) AU2013235234A1 (enExample)
CA (1) CA2865648A1 (enExample)
IL (1) IL234685A0 (enExample)
IN (1) IN2014DN07731A (enExample)
SA (1) SA113340401B1 (enExample)
SG (1) SG11201405347PA (enExample)
WO (1) WO2013142539A1 (enExample)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9475709B2 (en) * 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
US9193587B2 (en) 2011-07-13 2015-11-24 Lockheed Martin Corporation System and method for water purification and desalination
WO2013142133A1 (en) 2012-03-21 2013-09-26 Lockheed Martin Corporation Methods for perforating graphene using an activated gas stream and perforated graphene produced therefrom
US9095823B2 (en) * 2012-03-29 2015-08-04 Lockheed Martin Corporation Tunable layered membrane configuration for filtration and selective isolation and recovery devices
US9463421B2 (en) 2012-03-29 2016-10-11 Lockheed Martin Corporation Planar filtration and selective isolation and recovery device
US10653824B2 (en) 2012-05-25 2020-05-19 Lockheed Martin Corporation Two-dimensional materials and uses thereof
US9744617B2 (en) 2014-01-31 2017-08-29 Lockheed Martin Corporation Methods for perforating multi-layer graphene through ion bombardment
US9067811B1 (en) * 2012-05-25 2015-06-30 Lockheed Martin Corporation System, method, and control for graphenoid desalination
US9834809B2 (en) 2014-02-28 2017-12-05 Lockheed Martin Corporation Syringe for obtaining nano-sized materials for selective assays and related methods of use
US10376845B2 (en) 2016-04-14 2019-08-13 Lockheed Martin Corporation Membranes with tunable selectivity
US10418143B2 (en) 2015-08-05 2019-09-17 Lockheed Martin Corporation Perforatable sheets of graphene-based material
US10696554B2 (en) 2015-08-06 2020-06-30 Lockheed Martin Corporation Nanoparticle modification and perforation of graphene
US9610546B2 (en) 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US10980919B2 (en) 2016-04-14 2021-04-20 Lockheed Martin Corporation Methods for in vivo and in vitro use of graphene and other two-dimensional materials
US10118130B2 (en) 2016-04-14 2018-11-06 Lockheed Martin Corporation Two-dimensional membrane structures having flow passages
US9592475B2 (en) 2013-03-12 2017-03-14 Lockheed Martin Corporation Method for forming perforated graphene with uniform aperture size
US9505192B2 (en) 2013-03-13 2016-11-29 Lockheed Martin Corporation Nanoporous membranes and methods for making the same
US9480952B2 (en) 2013-03-14 2016-11-01 Lockheed Martin Corporation Methods for chemical reaction perforation of atomically thin materials
US9572918B2 (en) 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
JP2017510461A (ja) 2014-01-31 2017-04-13 ロッキード マーティン コーポレイションＬｏｃｋｈｅｅｄ Ｍａｒｔｉｎ Ｃｏｒｐｏｒａｔｉｏｎ 広幅イオン場を用いる二次元材料の穿孔
WO2015116857A2 (en) 2014-01-31 2015-08-06 Lockheed Martin Corporation Processes for forming composite structures with a two-dimensional material using a porous, non-sacrificial supporting layer
CA2942496A1 (en) 2014-03-12 2015-09-17 Lockheed Martin Corporation Separation membranes formed from perforated graphene
AU2015229296A1 (en) * 2014-03-12 2016-10-27 Lockheed Martin Corporation In vivo and in vitro use of graphene
WO2015138808A1 (en) * 2014-03-12 2015-09-17 Lockheed Martin Corporation Graphene-based molecular separation and sequestration device
WO2016036888A1 (en) * 2014-09-02 2016-03-10 Lockheed Martin Corporation Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same
KR20170113624A (ko) * 2015-02-06 2017-10-12 캐보트 코포레이션 요소 격리 조성물 및 방법
EP3443329A4 (en) 2016-04-14 2020-04-08 Lockheed Martin Corporation METHODS FOR PROVIDING IN SITU MONITORING AND CONTROL OF DEFECT TRAINING OR HEALING
WO2017180141A1 (en) 2016-04-14 2017-10-19 Lockheed Martin Corporation Selective interfacial mitigation of graphene defects
JP2019511451A (ja) 2016-04-14 2019-04-25 ロッキード・マーチン・コーポレーション 浮遊法を用いてグラフェンシートを大判転写用に処理する方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142463A1 (en) * 2001-10-11 2004-07-22 George Walker Methods, compositions, and automated systems for separating rare cells from fluid samples
US20100327847A1 (en) * 2007-09-12 2010-12-30 President And Fellows Of Harvard College High-Resolution Molecular Sensor
WO2011046706A1 (en) * 2009-09-18 2011-04-21 President And Fellows Of Harvard College Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis
US20120048804A1 (en) * 2010-08-25 2012-03-01 Lockheed Martin Corporation Perforated graphene deionization or desalination

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MA26028A1 (fr) 1997-01-09 2004-04-01 Garfield Int Invest Ltd Dessalement de l'eau
GB0100513D0 (en) 2001-01-09 2001-02-21 Smithkline Beecham Plc Process
JP3939943B2 (ja) 2001-08-29 2007-07-04 株式会社Ｇｓｉクレオス 気相成長法による炭素繊維からなるフィルター材
WO2004025250A2 (en) * 2002-09-11 2004-03-25 Temple University - Of The Commonwealth System Of Higher Education System and methods for electrophoretic separation of proteins on protein binding membranes
US7150813B2 (en) * 2003-06-12 2006-12-19 Palo Alto Research Center Incorporated Isoelectric focusing (IEF) of proteins with sequential and oppositely directed traveling waves in gel electrophoresis
US7410574B2 (en) 2004-03-03 2008-08-12 Patent Innovations Llc Magnetic particle filtration apparatus
DE102004062535A1 (de) 2004-12-24 2006-07-06 Forschungszentrum Karlsruhe Gmbh Semipermeables Membransystem für magnetische Partikelfraktionen
DE102005012594A1 (de) * 2005-03-18 2006-09-21 Bayer Technology Services Gmbh Elektrofiltrationsverfahren
US20100059378A1 (en) 2007-07-18 2010-03-11 The Water Company Llc Apparatus and method for removal of ions from a porous electrode that is part of a deionization system
US8409450B2 (en) * 2008-03-24 2013-04-02 The Regents Of The University Of California Graphene-based structure, method of suspending graphene membrane, and method of depositing material onto graphene membrane
US8147599B2 (en) 2009-02-17 2012-04-03 Mcalister Technologies, Llc Apparatuses and methods for storing and/or filtering a substance
EP2230511B1 (en) 2009-03-20 2017-04-26 Ecole Polytechnique Method for varying the diameter of a nanopore contained in a nanoporous membrane functionalised with a ph-dependent polyelectrolyte
AR077838A1 (es) 2009-08-10 2011-09-28 Danisco Us Inc Proceso basado en la filtracion tangencial en membrana para la recuperacion de proteinas
US8292092B2 (en) * 2009-09-08 2012-10-23 Teledyne Scientific & Imaging, Llc Macrocyclic pore-apertured carbon nanotube apparatus
WO2011063458A1 (en) 2009-11-25 2011-06-03 University Of Sydney Membrane and membrane separation system
US9751763B2 (en) 2010-07-14 2017-09-05 Monash University Material and applications therefor
JP2013535467A (ja) * 2010-07-28 2013-09-12 スマートセルズ・インコーポレイテツド 組換えにより発現されたインスリンポリペプチドおよびその使用
US9475709B2 (en) * 2010-08-25 2016-10-25 Lockheed Martin Corporation Perforated graphene deionization or desalination
WO2012030368A1 (en) 2010-09-01 2012-03-08 Lawrence Curtin Application of radio frequency to fluidized beds
KR101211850B1 (ko) 2010-09-01 2012-12-12 연세대학교 산학협력단 그라핀 나노 필터 망, 그라핀 나노 필터 및 그 제조방법
CN102242062B (zh) * 2011-04-19 2012-12-19 浙江大学 一种高分辨率的生物传感器
WO2013115762A1 (en) * 2012-01-27 2013-08-08 Empire Technology Development, Llc Accelerating transport through graphene membranes
US11135546B2 (en) * 2012-03-15 2021-10-05 Massachusetts Institute Of Technology Graphene based filter
WO2013142133A1 (en) * 2012-03-21 2013-09-26 Lockheed Martin Corporation Methods for perforating graphene using an activated gas stream and perforated graphene produced therefrom
US9067811B1 (en) * 2012-05-25 2015-06-30 Lockheed Martin Corporation System, method, and control for graphenoid desalination
US9610546B2 (en) * 2014-03-12 2017-04-04 Lockheed Martin Corporation Separation membranes formed from perforated graphene and methods for use thereof
US9592475B2 (en) * 2013-03-12 2017-03-14 Lockheed Martin Corporation Method for forming perforated graphene with uniform aperture size
US9572918B2 (en) * 2013-06-21 2017-02-21 Lockheed Martin Corporation Graphene-based filter for isolating a substance from blood
EP3074551B1 (en) * 2013-11-25 2023-11-22 Northeastern University Freestanding ultra thin membranes and transfer-free fabrication thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040142463A1 (en) * 2001-10-11 2004-07-22 George Walker Methods, compositions, and automated systems for separating rare cells from fluid samples
US20100327847A1 (en) * 2007-09-12 2010-12-30 President And Fellows Of Harvard College High-Resolution Molecular Sensor
WO2011046706A1 (en) * 2009-09-18 2011-04-21 President And Fellows Of Harvard College Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis
US20120048804A1 (en) * 2010-08-25 2012-03-01 Lockheed Martin Corporation Perforated graphene deionization or desalination

Also Published As

Publication number Publication date
US20130248367A1 (en) 2013-09-26
EP2827974A1 (en) 2015-01-28
IN2014DN07731A (enExample) 2015-05-15
WO2013142539A1 (en) 2013-09-26
AU2018200090A1 (en) 2018-01-25
CN104245094A (zh) 2014-12-24
SG11201405347PA (en) 2014-10-30
SA113340401B1 (ar) 2015-08-16
US20150218210A1 (en) 2015-08-06
AU2013235234A1 (en) 2014-10-16
KR20140147855A (ko) 2014-12-30
CN106823846A (zh) 2017-06-13
US9028663B2 (en) 2015-05-12
CA2865648A1 (en) 2013-09-26
JP2017100127A (ja) 2017-06-08
IL234685A0 (en) 2014-11-30

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