CA2865648A1 - Molecular separation device - Google Patents
Molecular separation device Download PDFInfo
- Publication number
- CA2865648A1 CA2865648A1 CA2865648A CA2865648A CA2865648A1 CA 2865648 A1 CA2865648 A1 CA 2865648A1 CA 2865648 A CA2865648 A CA 2865648A CA 2865648 A CA2865648 A CA 2865648A CA 2865648 A1 CA2865648 A1 CA 2865648A1
- Authority
- CA
- Canada
- Prior art keywords
- separation membrane
- membrane
- components
- blocked
- outer periphery
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000000926 separation method Methods 0.000 title claims abstract description 72
- 239000012528 membrane Substances 0.000 claims abstract description 108
- 238000000034 method Methods 0.000 claims abstract description 25
- 239000007900 aqueous suspension Substances 0.000 claims abstract description 17
- 230000000737 periodic effect Effects 0.000 claims abstract description 13
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 39
- 229910021389 graphene Inorganic materials 0.000 claims description 35
- 230000009919 sequestration Effects 0.000 claims description 12
- 239000007864 aqueous solution Substances 0.000 claims description 10
- 230000005012 migration Effects 0.000 claims description 10
- 238000013508 migration Methods 0.000 claims description 10
- 230000014759 maintenance of location Effects 0.000 claims description 4
- 230000000694 effects Effects 0.000 claims description 2
- 238000012546 transfer Methods 0.000 claims description 2
- 102000004169 proteins and genes Human genes 0.000 description 58
- 108090000623 proteins and genes Proteins 0.000 description 58
- 239000000463 material Substances 0.000 description 15
- 239000000725 suspension Substances 0.000 description 9
- 239000010410 layer Substances 0.000 description 8
- 230000008569 process Effects 0.000 description 5
- 239000000243 solution Substances 0.000 description 5
- XKRFYHLGVUSROY-UHFFFAOYSA-N Argon Chemical compound [Ar] XKRFYHLGVUSROY-UHFFFAOYSA-N 0.000 description 4
- 125000004432 carbon atom Chemical group C* 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 4
- 238000001914 filtration Methods 0.000 description 4
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 4
- 150000002500 ions Chemical class 0.000 description 4
- 239000002002 slurry Substances 0.000 description 4
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical group C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 3
- 230000009471 action Effects 0.000 description 3
- 238000003306 harvesting Methods 0.000 description 3
- 150000002430 hydrocarbons Chemical class 0.000 description 3
- 210000002381 plasma Anatomy 0.000 description 3
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 3
- 239000004926 polymethyl methacrylate Substances 0.000 description 3
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 3
- 102000015081 Blood Coagulation Factors Human genes 0.000 description 2
- 108010039209 Blood Coagulation Factors Proteins 0.000 description 2
- 239000004215 Carbon black (E152) Substances 0.000 description 2
- 208000031220 Hemophilia Diseases 0.000 description 2
- 208000009292 Hemophilia A Diseases 0.000 description 2
- 102000004877 Insulin Human genes 0.000 description 2
- 108090001061 Insulin Proteins 0.000 description 2
- 102000014150 Interferons Human genes 0.000 description 2
- 108010050904 Interferons Proteins 0.000 description 2
- 229910052786 argon Inorganic materials 0.000 description 2
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 2
- 239000003114 blood coagulation factor Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000001962 electrophoresis Methods 0.000 description 2
- 229960000301 factor viii Drugs 0.000 description 2
- 229930195733 hydrocarbon Natural products 0.000 description 2
- 229940125396 insulin Drugs 0.000 description 2
- 229940079322 interferon Drugs 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 230000003647 oxidation Effects 0.000 description 2
- 238000007254 oxidation reaction Methods 0.000 description 2
- 239000001301 oxygen Substances 0.000 description 2
- 229910052760 oxygen Inorganic materials 0.000 description 2
- 238000001020 plasma etching Methods 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 239000000047 product Substances 0.000 description 2
- 238000007670 refining Methods 0.000 description 2
- 230000002123 temporal effect Effects 0.000 description 2
- 208000030507 AIDS Diseases 0.000 description 1
- 241000283690 Bos taurus Species 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 238000005411 Van der Waals force Methods 0.000 description 1
- 125000004429 atom Chemical group 0.000 description 1
- 230000001363 autoimmune Effects 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 229920001400 block copolymer Polymers 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 150000001721 carbon Chemical group 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 230000005284 excitation Effects 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 230000006870 function Effects 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 206010025135 lupus erythematosus Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000002064 nanoplatelet Substances 0.000 description 1
- 239000002074 nanoribbon Substances 0.000 description 1
- 239000007800 oxidant agent Substances 0.000 description 1
- 238000000059 patterning Methods 0.000 description 1
- 239000012466 permeate Substances 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 238000001223 reverse osmosis Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000036962 time dependent Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/24—Extraction; Separation; Purification by electrochemical means
- C07K1/26—Electrophoresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D57/00—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C
- B01D57/02—Separation, other than separation of solids, not fully covered by a single other group or subclass, e.g. B03C by electrophoresis
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D35/00—Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
- B01D35/06—Filters making use of electricity or magnetism
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
- B01D71/02—Inorganic material
- B01D71/021—Carbon
- B01D71/0211—Graphene or derivates thereof
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2325/00—Details relating to properties of membranes
- B01D2325/20—Specific permeability or cut-off range
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D61/00—Processes of separation using semi-permeable membranes, e.g. dialysis, osmosis or ultrafiltration; Apparatus, accessories or auxiliary operations specially adapted therefor
- B01D61/14—Ultrafiltration; Microfiltration
- B01D61/18—Apparatus therefor
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/34—Extraction; Separation; Purification by filtration, ultrafiltration or reverse osmosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/36—Extraction; Separation; Purification by a combination of two or more processes of different types
Landscapes
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Electrochemistry (AREA)
- Molecular Biology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Water Supply & Treatment (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Inorganic Chemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Environmental & Geological Engineering (AREA)
- General Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Separation Using Semi-Permeable Membranes (AREA)
- Urology & Nephrology (AREA)
- Electrostatic Separation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261613578P | 2012-03-21 | 2012-03-21 | |
| US61/613,578 | 2012-03-21 | ||
| PCT/US2013/033035 WO2013142539A1 (en) | 2012-03-21 | 2013-03-20 | Molecular separation device |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2865648A1 true CA2865648A1 (en) | 2013-09-26 |
Family
ID=48050312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2865648A Abandoned CA2865648A1 (en) | 2012-03-21 | 2013-03-20 | Molecular separation device |
Country Status (12)
| Country | Link |
|---|---|
| US (2) | US9028663B2 (enExample) |
| EP (1) | EP2827974A1 (enExample) |
| JP (2) | JP2015511531A (enExample) |
| KR (1) | KR20140147855A (enExample) |
| CN (2) | CN106823846A (enExample) |
| AU (2) | AU2013235234A1 (enExample) |
| CA (1) | CA2865648A1 (enExample) |
| IL (1) | IL234685A0 (enExample) |
| IN (1) | IN2014DN07731A (enExample) |
| SA (1) | SA113340401B1 (enExample) |
| SG (1) | SG11201405347PA (enExample) |
| WO (1) | WO2013142539A1 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9475709B2 (en) | 2010-08-25 | 2016-10-25 | Lockheed Martin Corporation | Perforated graphene deionization or desalination |
| US9193587B2 (en) | 2011-07-13 | 2015-11-24 | Lockheed Martin Corporation | System and method for water purification and desalination |
| KR20140146131A (ko) | 2012-03-21 | 2014-12-24 | 록히드 마틴 코포레이션 | 활성화 가스 스트림을 사용하여 그래핀을 천공하기 위한 방법들 및 그것으로부터 제조되는 천공된 그래핀 |
| US9463421B2 (en) | 2012-03-29 | 2016-10-11 | Lockheed Martin Corporation | Planar filtration and selective isolation and recovery device |
| US9095823B2 (en) * | 2012-03-29 | 2015-08-04 | Lockheed Martin Corporation | Tunable layered membrane configuration for filtration and selective isolation and recovery devices |
| US9610546B2 (en) | 2014-03-12 | 2017-04-04 | Lockheed Martin Corporation | Separation membranes formed from perforated graphene and methods for use thereof |
| US10980919B2 (en) | 2016-04-14 | 2021-04-20 | Lockheed Martin Corporation | Methods for in vivo and in vitro use of graphene and other two-dimensional materials |
| US10418143B2 (en) | 2015-08-05 | 2019-09-17 | Lockheed Martin Corporation | Perforatable sheets of graphene-based material |
| US9834809B2 (en) | 2014-02-28 | 2017-12-05 | Lockheed Martin Corporation | Syringe for obtaining nano-sized materials for selective assays and related methods of use |
| US20150258498A1 (en) * | 2014-03-12 | 2015-09-17 | Lockheed Martin Corporation | Graphene-based molecular separation and sequestration device and methods for harvest and recovery |
| US10653824B2 (en) | 2012-05-25 | 2020-05-19 | Lockheed Martin Corporation | Two-dimensional materials and uses thereof |
| US10376845B2 (en) | 2016-04-14 | 2019-08-13 | Lockheed Martin Corporation | Membranes with tunable selectivity |
| US9744617B2 (en) | 2014-01-31 | 2017-08-29 | Lockheed Martin Corporation | Methods for perforating multi-layer graphene through ion bombardment |
| US9067811B1 (en) * | 2012-05-25 | 2015-06-30 | Lockheed Martin Corporation | System, method, and control for graphenoid desalination |
| US10005038B2 (en) | 2014-09-02 | 2018-06-26 | Lockheed Martin Corporation | Hemodialysis and hemofiltration membranes based upon a two-dimensional membrane material and methods employing same |
| WO2014164621A1 (en) | 2013-03-12 | 2014-10-09 | Lockheed Martin Corporation | Method for forming filter with uniform aperture size |
| CN105102105A (zh) | 2013-03-13 | 2015-11-25 | 洛克希德马丁公司 | 纳米多孔薄膜及其制造方法 |
| US9480952B2 (en) | 2013-03-14 | 2016-11-01 | Lockheed Martin Corporation | Methods for chemical reaction perforation of atomically thin materials |
| US9572918B2 (en) | 2013-06-21 | 2017-02-21 | Lockheed Martin Corporation | Graphene-based filter for isolating a substance from blood |
| EP3100297A4 (en) | 2014-01-31 | 2017-12-13 | Lockheed Martin Corporation | Perforating two-dimensional materials using broad ion field |
| JP2017507044A (ja) | 2014-01-31 | 2017-03-16 | ロッキード マーティン コーポレイションＬｏｃｋｈｅｅｄ Ｍａｒｔｉｎ Ｃｏｒｐｏｒａｔｉｏｎ | 多孔性非犠牲支持層を用いた二次元材料とのコンポジット構造を形成するための方法 |
| CN106232205A (zh) | 2014-03-12 | 2016-12-14 | 洛克希德马丁公司 | 由有孔石墨烯形成的分离膜 |
| MX2016011812A (es) * | 2014-03-12 | 2017-05-09 | Lockheed Corp | Uso in vivo e in vitro de grafeno. |
| CN107405539A (zh) * | 2015-02-06 | 2017-11-28 | 卡博特公司 | 脲隔离组合物及方法 |
| AU2016303049A1 (en) | 2015-08-06 | 2018-03-01 | Lockheed Martin Corporation | Nanoparticle modification and perforation of graphene |
| JP2019517909A (ja) | 2016-04-14 | 2019-06-27 | ロッキード・マーチン・コーポレーション | 流路を有する二次元膜構造体 |
| EP3442739A4 (en) | 2016-04-14 | 2020-03-04 | Lockheed Martin Corporation | PROCESS FOR PROCESSING GRAPHENE SHEETS FOR LARGE SCALE TRANSFER USING A FREE FLOATING PROCESS |
| KR20190018411A (ko) | 2016-04-14 | 2019-02-22 | 록히드 마틴 코포레이션 | 그래핀 결함의 선택적 계면 완화 |
| SG11201808961QA (en) | 2016-04-14 | 2018-11-29 | Lockheed Corp | Methods for in situ monitoring and control of defect formation or healing |
Family Cites Families (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MA26028A1 (fr) | 1997-01-09 | 2004-04-01 | Garfield Int Invest Ltd | Dessalement de l'eau |
| GB0100513D0 (en) | 2001-01-09 | 2001-02-21 | Smithkline Beecham Plc | Process |
| JP3939943B2 (ja) | 2001-08-29 | 2007-07-04 | 株式会社Ｇｓｉクレオス | 気相成長法による炭素繊維からなるフィルター材 |
| US7166443B2 (en) | 2001-10-11 | 2007-01-23 | Aviva Biosciences Corporation | Methods, compositions, and automated systems for separating rare cells from fluid samples |
| AU2003267094A1 (en) * | 2002-09-11 | 2004-04-30 | Temple University - Of The Commonwealth System Of Higher Education | System and methods for electrophoretic separation of proteins on protein binding membranes |
| US7150813B2 (en) * | 2003-06-12 | 2006-12-19 | Palo Alto Research Center Incorporated | Isoelectric focusing (IEF) of proteins with sequential and oppositely directed traveling waves in gel electrophoresis |
| US7410574B2 (en) | 2004-03-03 | 2008-08-12 | Patent Innovations Llc | Magnetic particle filtration apparatus |
| DE102004062535A1 (de) | 2004-12-24 | 2006-07-06 | Forschungszentrum Karlsruhe Gmbh | Semipermeables Membransystem für magnetische Partikelfraktionen |
| DE102005012594A1 (de) * | 2005-03-18 | 2006-09-21 | Bayer Technology Services Gmbh | Elektrofiltrationsverfahren |
| US20100059378A1 (en) | 2007-07-18 | 2010-03-11 | The Water Company Llc | Apparatus and method for removal of ions from a porous electrode that is part of a deionization system |
| EP3540436B1 (en) | 2007-09-12 | 2023-11-01 | President And Fellows Of Harvard College | High-resolution molecular sensor |
| US8409450B2 (en) * | 2008-03-24 | 2013-04-02 | The Regents Of The University Of California | Graphene-based structure, method of suspending graphene membrane, and method of depositing material onto graphene membrane |
| US8147599B2 (en) | 2009-02-17 | 2012-04-03 | Mcalister Technologies, Llc | Apparatuses and methods for storing and/or filtering a substance |
| EP2230511B1 (en) | 2009-03-20 | 2017-04-26 | Ecole Polytechnique | Method for varying the diameter of a nanopore contained in a nanoporous membrane functionalised with a ph-dependent polyelectrolyte |
| US8993294B2 (en) | 2009-08-10 | 2015-03-31 | Danisco Us Inc. | Cross-flow membrane filtration-based process for protein recovery |
| US8292092B2 (en) * | 2009-09-08 | 2012-10-23 | Teledyne Scientific & Imaging, Llc | Macrocyclic pore-apertured carbon nanotube apparatus |
| EP3196645B1 (en) * | 2009-09-18 | 2019-06-19 | President and Fellows of Harvard College | Bare single-layer graphene membrane having a nanopore enabling high-sensitivity molecular detection and analysis |
| CN102781558B (zh) | 2009-11-25 | 2015-06-24 | 悉尼大学 | 膜及膜分离系统 |
| EP2593403B1 (en) | 2010-07-14 | 2020-03-04 | Monash University | Method for producing a gel film and filtration membrane prepared with this method |
| CA2806399A1 (en) * | 2010-07-28 | 2012-02-02 | Smartcells, Inc. | Recombinantly expressed insulin polypeptides and uses thereof |
| US9475709B2 (en) * | 2010-08-25 | 2016-10-25 | Lockheed Martin Corporation | Perforated graphene deionization or desalination |
| US8361321B2 (en) | 2010-08-25 | 2013-01-29 | Lockheed Martin Corporation | Perforated graphene deionization or desalination |
| KR101211850B1 (ko) | 2010-09-01 | 2012-12-12 | 연세대학교 산학협력단 | 그라핀 나노 필터 망, 그라핀 나노 필터 및 그 제조방법 |
| WO2012030368A1 (en) | 2010-09-01 | 2012-03-08 | Lawrence Curtin | Application of radio frequency to fluidized beds |
| CN102242062B (zh) * | 2011-04-19 | 2012-12-19 | 浙江大学 | 一种高分辨率的生物传感器 |
| US9056282B2 (en) * | 2012-01-27 | 2015-06-16 | Empire Technology Development Llc | Accelerating transport through graphene membranes |
| CN104411642B (zh) * | 2012-03-15 | 2018-04-03 | 麻省理工学院 | 基于石墨烯的过滤器 |
| KR20140146131A (ko) * | 2012-03-21 | 2014-12-24 | 록히드 마틴 코포레이션 | 활성화 가스 스트림을 사용하여 그래핀을 천공하기 위한 방법들 및 그것으로부터 제조되는 천공된 그래핀 |
| US9610546B2 (en) * | 2014-03-12 | 2017-04-04 | Lockheed Martin Corporation | Separation membranes formed from perforated graphene and methods for use thereof |
| US9067811B1 (en) * | 2012-05-25 | 2015-06-30 | Lockheed Martin Corporation | System, method, and control for graphenoid desalination |
| WO2014164621A1 (en) * | 2013-03-12 | 2014-10-09 | Lockheed Martin Corporation | Method for forming filter with uniform aperture size |
| US9572918B2 (en) * | 2013-06-21 | 2017-02-21 | Lockheed Martin Corporation | Graphene-based filter for isolating a substance from blood |
| WO2015077751A1 (en) * | 2013-11-25 | 2015-05-28 | Northeastern University | Freestanding ultra thin membranes and transfer-free fabrication thereof |
-
2013
- 2013-03-14 US US13/804,085 patent/US9028663B2/en not_active Expired - Fee Related
- 2013-03-20 SA SA113340401A patent/SA113340401B1/ar unknown
- 2013-03-20 CA CA2865648A patent/CA2865648A1/en not_active Abandoned
- 2013-03-20 JP JP2015501867A patent/JP2015511531A/ja active Pending
- 2013-03-20 CN CN201710120140.6A patent/CN106823846A/zh active Pending
- 2013-03-20 EP EP13714806.0A patent/EP2827974A1/en not_active Withdrawn
- 2013-03-20 CN CN201380014845.XA patent/CN104245094A/zh active Pending
- 2013-03-20 SG SG11201405347PA patent/SG11201405347PA/en unknown
- 2013-03-20 WO PCT/US2013/033035 patent/WO2013142539A1/en not_active Ceased
- 2013-03-20 AU AU2013235234A patent/AU2013235234A1/en not_active Abandoned
- 2013-03-20 KR KR1020147029539A patent/KR20140147855A/ko not_active Withdrawn
- 2013-03-20 IN IN7731DEN2014 patent/IN2014DN07731A/en unknown
-
2014
- 2014-09-16 IL IL234685A patent/IL234685A0/en unknown
-
2015
- 2015-04-14 US US14/686,452 patent/US20150218210A1/en not_active Abandoned
-
2017
- 2017-01-11 JP JP2017002652A patent/JP2017100127A/ja active Pending
-
2018
- 2018-01-05 AU AU2018200090A patent/AU2018200090A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| IL234685A0 (en) | 2014-11-30 |
| AU2013235234A1 (en) | 2014-10-16 |
| KR20140147855A (ko) | 2014-12-30 |
| CN104245094A (zh) | 2014-12-24 |
| JP2017100127A (ja) | 2017-06-08 |
| AU2018200090A1 (en) | 2018-01-25 |
| US20150218210A1 (en) | 2015-08-06 |
| US9028663B2 (en) | 2015-05-12 |
| US20130248367A1 (en) | 2013-09-26 |
| EP2827974A1 (en) | 2015-01-28 |
| CN106823846A (zh) | 2017-06-13 |
| JP2015511531A (ja) | 2015-04-20 |
| WO2013142539A1 (en) | 2013-09-26 |
| SG11201405347PA (en) | 2014-10-30 |
| IN2014DN07731A (enExample) | 2015-05-15 |
| SA113340401B1 (ar) | 2015-08-16 |
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| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20180320 |
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| FZDE | Discontinued |
Effective date: 20210831 |