JP2015508892A - 慢性ｂ型肝炎患者の応答予測及び治療観察のためのｂ型肝炎ウイルス免疫複合体 - Google Patents

慢性ｂ型肝炎患者の応答予測及び治療観察のためのｂ型肝炎ウイルス免疫複合体 Download PDF

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JP2015508892A
JP2015508892A JP2014557064A JP2014557064A JP2015508892A JP 2015508892 A JP2015508892 A JP 2015508892A JP 2014557064 A JP2014557064 A JP 2014557064A JP 2014557064 A JP2014557064 A JP 2014557064A JP 2015508892 A JP2015508892 A JP 2015508892A
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hbv
amount
immune complex
subject
interferon therapy
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JP2015508892A5 (https=
Inventor
クラウゼ，ウルスラ
ヒップ，ベルトホルト
グルナート，ファイト・ペーター
ウプマイヤー，バーバラ
ロパティン，ユーリ
ニート，アンニッキ デ
ニート，アンニッキ デ
リーシンク，ヘンク
ザーアイアー，ハンス
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F Hoffmann La Roche AG
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F Hoffmann La Roche AG
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Publication of JP2015508892A publication Critical patent/JP2015508892A/ja
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/576—Immunoassay; Biospecific binding assay; Materials therefor for hepatitis
    • G01N33/5761—Hepatitis B
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/02—Hepadnaviridae, e.g. hepatitis B virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2014557064A 2012-02-20 2013-02-18 慢性ｂ型肝炎患者の応答予測及び治療観察のためのｂ型肝炎ウイルス免疫複合体 Pending JP2015508892A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12156192.2A EP2629096A1 (en) 2012-02-20 2012-02-20 HBV immunocomplexes for response prediction and therapy monitoring of chronic HBV patients
EP12156192.2 2012-02-20
PCT/EP2013/053150 WO2013124229A1 (en) 2012-02-20 2013-02-18 Hbv immunocomplexes for response prediction and therapy monitoring of chronic hbv patients

Publications (2)

Publication Number Publication Date
JP2015508892A true JP2015508892A (ja) 2015-03-23
JP2015508892A5 JP2015508892A5 (https=) 2016-04-07

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ID=47757571

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JP2014557064A Pending JP2015508892A (ja) 2012-02-20 2013-02-18 慢性ｂ型肝炎患者の応答予測及び治療観察のためのｂ型肝炎ウイルス免疫複合体

Country Status (7)

Country Link
US (1) US20150192583A1 (https=)
EP (2) EP2629096A1 (https=)
JP (1) JP2015508892A (https=)
CN (1) CN104126124A (https=)
CA (1) CA2863106A1 (https=)
HK (1) HK1203616A1 (https=)
WO (1) WO2013124229A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016159178A1 (ja) * 2015-03-30 2016-10-06 雅史 溝上 インターフェロン治療効果予測方法及びそれを用いたｂ型肝炎患者の治療用医薬組成物

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HK1250744A1 (zh) * 2015-07-15 2019-01-11 F. Hoffmann-La Roche Ag Hbv治疗应答的生物标志物
US20190339275A1 (en) * 2016-11-11 2019-11-07 Melbourne Health Assay for determining hepatitis b clearance
TW201928064A (zh) * 2017-12-21 2019-07-16 紐西蘭商紐西蘭健康創新中心管理有限公司 B型肝炎病毒之突變分析方法及其應用
US12235273B2 (en) 2018-05-04 2025-02-25 Abbott Laboratories HBV diagnostic, prognostic, and therapeutic methods and products
CN110564894B (zh) * 2019-09-10 2023-04-07 深圳市罗湖区人民医院 干扰物对荧光定量pcr检测hbv dna的干扰评价方法
CN111474187A (zh) * 2020-04-09 2020-07-31 三峡大学 一种免疫电镜免疫反应盒
CN115466802B (zh) * 2022-10-28 2023-12-12 北京大学 Tp53bp2在调控干扰素信号通路及抗病毒中的用途

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09511577A (ja) * 1994-03-31 1997-11-18 ザ スクリップス リサーチ インスティチュート 慢性肝炎ｂ型ウイルス感染の診断方法
JP2010526307A (ja) * 2007-05-08 2010-07-29 エフ．ホフマン−ラ ロシュ アーゲー 特異的免疫グロブリンクラスｇ抗体の検出方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003502384A (ja) * 1999-06-22 2003-01-21 カイロン コーポレイション 慢性ｈｂｖ感染を処置するための方法
CN1261455C (zh) * 2002-07-19 2006-06-28 余宙耀 一种重组人源性抗乙肝表面抗原（HBsAg）Fab抗体及其制取方法
DE10339927A1 (de) * 2003-08-29 2005-03-24 Rhein Biotech Gesellschaft für neue Biotechnologische Prozesse und Produkte mbH Zusammensetzung zur Prophylaxe/Therapie von HBV-Infektionen und HBV-vermittelten Erkrankungen
GB0326416D0 (en) * 2003-11-12 2003-12-17 Karolinska Innovations Ab Methods and means relating to hepatitis B infection
US20090170926A1 (en) * 2004-03-31 2009-07-02 Monash Univeristy Antiviral agents
US20120035347A1 (en) * 2009-04-14 2012-02-09 Schering Corporation Interferon-alfa sensitivity biomarkers

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09511577A (ja) * 1994-03-31 1997-11-18 ザ スクリップス リサーチ インスティチュート 慢性肝炎ｂ型ウイルス感染の診断方法
JP2010526307A (ja) * 2007-05-08 2010-07-29 エフ．ホフマン−ラ ロシュ アーゲー 特異的免疫グロブリンクラスｇ抗体の検出方法

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2016159178A1 (ja) * 2015-03-30 2016-10-06 雅史 溝上 インターフェロン治療効果予測方法及びそれを用いたｂ型肝炎患者の治療用医薬組成物

Also Published As

Publication number Publication date
CA2863106A1 (en) 2013-08-29
EP2629096A1 (en) 2013-08-21
CN104126124A (zh) 2014-10-29
WO2013124229A1 (en) 2013-08-29
HK1203616A1 (en) 2015-10-30
US20150192583A1 (en) 2015-07-09
EP2817631A1 (en) 2014-12-31

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