JP2015504661A5 - - Google Patents
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- JP2015504661A5 JP2015504661A5 JP2014548844A JP2014548844A JP2015504661A5 JP 2015504661 A5 JP2015504661 A5 JP 2015504661A5 JP 2014548844 A JP2014548844 A JP 2014548844A JP 2014548844 A JP2014548844 A JP 2014548844A JP 2015504661 A5 JP2015504661 A5 JP 2015504661A5
- Authority
- JP
- Japan
- Prior art keywords
- chronotype
- same
- clan
- region
- profile
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 238000000034 method Methods 0.000 claims 18
- 108020004707 nucleic acids Proteins 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- 102000039446 nucleic acids Human genes 0.000 claims 4
- 108020004511 Recombinant DNA Proteins 0.000 claims 3
- 108700005091 Immunoglobulin Genes Proteins 0.000 claims 2
- 210000003719 b-lymphocyte Anatomy 0.000 claims 2
- 201000003444 follicular lymphoma Diseases 0.000 claims 2
- 238000012804 iterative process Methods 0.000 claims 2
- 239000002773 nucleotide Substances 0.000 claims 2
- 125000003729 nucleotide group Chemical group 0.000 claims 2
- 230000009466 transformation Effects 0.000 claims 2
- 208000003950 B-cell lymphoma Diseases 0.000 claims 1
- 208000031671 Large B-Cell Diffuse Lymphoma Diseases 0.000 claims 1
- 210000004027 cell Anatomy 0.000 claims 1
- 206010012818 diffuse large B-cell lymphoma Diseases 0.000 claims 1
- 238000013507 mapping Methods 0.000 claims 1
- 238000005259 measurement Methods 0.000 claims 1
- 238000005215 recombination Methods 0.000 claims 1
- 230000006798 recombination Effects 0.000 claims 1
- 230000003252 repetitive effect Effects 0.000 claims 1
- 238000012163 sequencing technique Methods 0.000 claims 1
- 238000011144 upstream manufacturing Methods 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161578175P | 2011-12-20 | 2011-12-20 | |
| US61/578,175 | 2011-12-20 | ||
| PCT/US2012/070674 WO2013096480A2 (en) | 2011-12-20 | 2012-12-19 | Monitoring transformation of follicular lymphoma to diffuse large b-cell lymphoma by immune repertoire analysis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2015504661A JP2015504661A (ja) | 2015-02-16 |
| JP2015504661A5 true JP2015504661A5 (https=) | 2017-01-19 |
Family
ID=48669695
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014548844A Pending JP2015504661A (ja) | 2011-12-20 | 2012-12-19 | 免疫レパートリー解析による、濾胞性リンパ腫からびまん性大細胞型ｂ細胞リンパ腫への形質転換のモニタリング |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US20140349883A1 (https=) |
| EP (1) | EP2794925A4 (https=) |
| JP (1) | JP2015504661A (https=) |
| WO (1) | WO2013096480A2 (https=) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9394567B2 (en) | 2008-11-07 | 2016-07-19 | Adaptive Biotechnologies Corporation | Detection and quantification of sample contamination in immune repertoire analysis |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| CN104195227B (zh) | 2008-11-07 | 2017-04-12 | 适应生物技术公司 | 通过序列分析监测状况的方法 |
| EP2387627B1 (en) | 2009-01-15 | 2016-03-30 | Adaptive Biotechnologies Corporation | Adaptive immunity profiling and methods for generation of monoclonal antibodies |
| CN102459643B (zh) | 2009-06-25 | 2016-06-01 | 弗雷德哈钦森癌症研究中心 | 检测获得性免疫的方法 |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| EP2768982A4 (en) | 2011-10-21 | 2015-06-03 | Adaptive Biotechnologies Corp | QUANTIFICATION OF ADAPTIVE IMMUNOCELL GENOMES IN A COMPLEX MIX OF CELLS |
| US9824179B2 (en) | 2011-12-09 | 2017-11-21 | Adaptive Biotechnologies Corp. | Diagnosis of lymphoid malignancies and minimal residual disease detection |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| DK2823060T3 (en) | 2012-03-05 | 2018-05-28 | Adaptive Biotechnologies Corp | Determination of associated immune receptor chains from frequency-matched subunits |
| CA2872468C (en) | 2012-05-08 | 2020-10-27 | Adaptive Biotechnologies Corporation | Compositions and methods for measuring and calibrating amplification bias in multiplexed pcr reactions |
| JP6449160B2 (ja) | 2012-10-01 | 2019-01-09 | アダプティブ バイオテクノロジーズ コーポレイション | 適応免疫受容体多様性およびクローン性特性決定による免疫能力評価関連出願の相互参照 |
| US10150996B2 (en) | 2012-10-19 | 2018-12-11 | Adaptive Biotechnologies Corp. | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| WO2015134787A2 (en) | 2014-03-05 | 2015-09-11 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| CA2966201A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| WO2016086029A1 (en) | 2014-11-25 | 2016-06-02 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| CA2976580A1 (en) | 2015-02-24 | 2016-09-01 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
| AU2016242967B2 (en) | 2015-04-01 | 2021-07-01 | Adaptive Biotechnologies Corp. | Method of identifying human compatible T cell receptors specific for an antigenic target |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| WO2021151114A1 (en) * | 2020-01-22 | 2021-07-29 | Life Technologies Corporation | Immune repertoire biomarkers in autoimmune disease and immunodeficiency disorders |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8748103B2 (en) * | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| EP4219759A3 (en) * | 2010-05-06 | 2023-09-06 | Adaptive Biotechnologies Corporation | Monitoring health and disease status using clonotype profiles |
-
2012
- 2012-12-19 WO PCT/US2012/070674 patent/WO2013096480A2/en not_active Ceased
- 2012-12-19 JP JP2014548844A patent/JP2015504661A/ja active Pending
- 2012-12-19 US US14/366,840 patent/US20140349883A1/en not_active Abandoned
- 2012-12-19 EP EP12859772.1A patent/EP2794925A4/en not_active Withdrawn
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