JP2015504430A - Ｉｌ−７アンタゴニスト及びｐｓａ応答又は非応答対立遺伝子を用いた乾癬性関節炎（ｐｓａ）を治療する方法 - Google Patents
Ｉｌ−７アンタゴニスト及びｐｓａ応答又は非応答対立遺伝子を用いた乾癬性関節炎（ｐｓａ）を治療する方法 Download PDFInfo
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| US8710200B2 (en) | 2011-03-31 | 2014-04-29 | Moderna Therapeutics, Inc. | Engineered nucleic acids encoding a modified erythropoietin and their expression |
| US9464124B2 (en) | 2011-09-12 | 2016-10-11 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| ES2911677T3 (es) | 2011-10-03 | 2022-05-20 | Modernatx Inc | Nucleósidos, nucleótidos y ácidos nucleicos modificados, y sus usos |
| MX2014007233A (es) | 2011-12-16 | 2015-02-04 | Moderna Therapeutics Inc | Composiciones de nucleosidos, nucleotidos y acidos nucleicos modificados. |
| US9572897B2 (en) | 2012-04-02 | 2017-02-21 | Modernatx, Inc. | Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins |
| WO2013151663A1 (en) | 2012-04-02 | 2013-10-10 | modeRNA Therapeutics | Modified polynucleotides for the production of membrane proteins |
| US9283287B2 (en) | 2012-04-02 | 2016-03-15 | Moderna Therapeutics, Inc. | Modified polynucleotides for the production of nuclear proteins |
| US9878056B2 (en) | 2012-04-02 | 2018-01-30 | Modernatx, Inc. | Modified polynucleotides for the production of cosmetic proteins and peptides |
| PT2922554T (pt) | 2012-11-26 | 2022-06-28 | Modernatx Inc | Arn modificado nas porções terminais |
| US8980864B2 (en) | 2013-03-15 | 2015-03-17 | Moderna Therapeutics, Inc. | Compositions and methods of altering cholesterol levels |
| WO2015048744A2 (en) | 2013-09-30 | 2015-04-02 | Moderna Therapeutics, Inc. | Polynucleotides encoding immune modulating polypeptides |
| WO2015051214A1 (en) | 2013-10-03 | 2015-04-09 | Moderna Therapeutics, Inc. | Polynucleotides encoding low density lipoprotein receptor |
| US11548940B2 (en) | 2014-05-15 | 2023-01-10 | Rani Therapeutics, Llc | Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device |
| CA2949236C (en) | 2014-05-15 | 2023-06-13 | Incube Labs, Llc | Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins |
| EP3191120B1 (en) * | 2014-09-10 | 2024-04-10 | Novartis Ag | Use of il-17 antagonists to inhibit the progression of structural damage in psoriatic arthritis patients |
| AR103173A1 (es) | 2014-12-22 | 2017-04-19 | Novarits Ag | Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17 |
| AR103172A1 (es) | 2014-12-22 | 2017-04-19 | Novartis Ag | Reducción selectiva de residuos de cisteina en anticuerpos il-17 |
| US20160244520A1 (en) * | 2015-01-24 | 2016-08-25 | Abbvie Inc. | Compositions and methods for treating psoriatic arthritis |
| KR20240156437A (ko) | 2015-10-27 | 2024-10-29 | 유씨비 바이오파마 에스알엘 | 항-il-17a/f 항체를 사용한 치료 방법 |
| CA3120237A1 (en) * | 2018-11-20 | 2020-05-28 | Janssen Biotech, Inc. | Safe and effective method of treating psoriasis with anti-il-23 specific antibody |
| AU2020288749A1 (en) * | 2019-06-04 | 2022-02-03 | Janssen Biotech, Inc. | Safe and effective method of treating psoriatic arthritis with anti-IL23 specific antibody |
| WO2021053591A1 (en) * | 2019-09-20 | 2021-03-25 | Novartis Ag | Methods of treating autoimmune diseases using interleukin-17 (il-17) antagonists |
| EP4305062A1 (en) * | 2021-03-12 | 2024-01-17 | Janssen Biotech, Inc. | Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody |
| MX2023010705A (es) * | 2021-03-12 | 2023-11-22 | Janssen Biotech Inc | Método seguro y eficaz para tratar la artritis psoriásica con el anticuerpo específico anti-il23. |
| CN114427001A (zh) * | 2022-01-29 | 2022-05-03 | 中日友好医院(中日友好临床医学研究所) | 基于78个snp位点评估阿达木单抗治疗银屑病有效性的试剂盒 |
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| US7838638B2 (en) | 2005-12-13 | 2010-11-23 | Eli Lilly And Company | Anti-IL-17 antibodies |
| RU2430110C2 (ru) | 2006-01-31 | 2011-09-27 | Новартис Аг | Антитела - антагонисты интерлейкина-17 (ил-17) для лечения рака |
| GB0612928D0 (en) | 2006-06-29 | 2006-08-09 | Ucb Sa | Biological products |
| BRPI0813262A2 (pt) * | 2007-06-20 | 2015-04-14 | Schering Corp | Biomarcadores de destruição de articulação para terapia de doença inflamatória de articulação anti-il-17a |
| ES2493042T3 (es) | 2008-09-29 | 2014-09-11 | Roche Glycart Ag | Anticuerpos contra la IL-17 humana y usos de los mismos |
| US20120178100A1 (en) * | 2009-07-28 | 2012-07-12 | Centocor Ortho Biotech Inc. | Serum Markers Predicting Clinical Response to Anti-TNF Alpha Antibodies in Patients with Psoriatic Arthritis |
| CN107029234A (zh) * | 2010-10-08 | 2017-08-11 | 诺华有限公司 | 利用il‑17拮抗剂治疗牛皮癣的方法 |
| WO2012082573A1 (en) * | 2010-12-13 | 2012-06-21 | Novartis Ag | Predictive methods and methods of treating arthritis using il-17 antagonists |
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| JP2008507988A (ja) * | 2004-08-05 | 2008-03-21 | ノバルティス アクチエンゲゼルシャフト | Ｉｌ−１７拮抗性抗体 |
Non-Patent Citations (6)
| Title |
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| JPN6016009264; ＬＡＭＢＥＲＴ Ｓ． ｅｔ ａｌ．: 'ＴＲＡＦ３ＩＰ２ ｃｏｕｐｌｅｓ ＩＬ-１７ ｔｏ ｔｈｅ ｅｐｉｄｅｒｍａｌ ｄｅｆｅｎｓｅ ｒｅｓｐｏｎｓｅ' Ｊｏｕｒｎａｌ ｏｆ Ｉｎｖｅｓｔｉｇａｔｉｖｅ Ｄｅｒｍａｔｏｌｏｇｙ Ｖｏｌ．１３１， Ｓｕｐｐｌ．２, 201109, ｐ．Ｓ１９， Ａｂｓｔｒａｃｔ Ｎｏ．１１２ * |
| JPN6016009265; ＬＡＭＢＥＲＴ Ｓ． ｅｔ ａｌ．: 'ＴＲＡＦ３ＩＰ２ ｃｏｕｐｌｅｓ ＩＬ-１７ ｔｏ ｔｈｅ ｅｐｉｄｅｒｍａｌ ｄｅｆｅｎｓｅ ｒｅｓｐｏｎｓｅ' Ｊｏｕｒｎａｌ ｏｆ Ｉｎｖｅｓｔｉｇａｔｉｖｅ Ｄｅｒｍａｔｏｌｏｇｙ Ｖｏｌ．１３１， Ｓｕｐｐｌ．１, 201104, ｐ．Ｓ６， Ａｂｓｔｒａｃｔ Ｎｏ．０３４ * |
| JPN6016009266; ＶＥＬＩＣＨＫＯ Ｓ． ｅｔ ａｌ．: 'Ｇｌｏｂａｌ ｇｅｎｅ ｅｘｐｒｅｓｓｉｏｎ ａｎａｌｙｓｉｓ ｏｆ Ａｃｔ１'ｓ ｅｆｆｅｃｔｓ ｉｎ ａｉｒｗａｙ ｅｐｉｔｈｅｌｉａｌ ｃｅｌｌｓ' Ｊｏｕｒｎａｌ ｏｆ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．１８６， ＭｅｅｔｉｎｇＡｂｓｔｒａｃｔｓ, 201104, Ａｂｓｔｒａｃｔ Ｎｏ．１６１．１７ * |
| JPN6016009267; ＥＬＬＩＮＧＨＡＵＳ Ｅ． ｅｔ ａｌ．: 'Ｇｅｎｏｍｅ-ｗｉｄｅ ａｓｓｏｃｉａｔｉｏｎ ｓｔｕｄｙ ｉｄｅｎｔｉｆｉｅｓ ａ ｐｓｏｒｉａｓｉｓ ｓｕｓｃｅｐｔｉｂｉｌｉｔｙ ｌｏｃｕｓ ａｔ ＴＲＡＦ３ＩＰ２' Ｎａｔｕｒｅ Ｇｅｎｅｔｉｃｓ Ｖｏｌ．４２， Ｎｏ．１１, 2010, ｐ．９９１-５ * |
| JPN6016009268; ＧＬＡＤＭＡＮ Ｄ．Ｄ． ｅｔ ａｌ．: 'ＨＬＡ-ＤＲＢ１＊０４ ａｌｌｅｌｅｓ ｉｎ ｐｓｏｒｉａｔｉｃ ａｒｔｈｒｉｔｉｓ： ｃｏｍｐａｒｉｓｏｎ ｗｉｔｈ ｒｈｅｕｍａｔｏｉｄ ａｒｔｈｒｉｔｉｓ ａｎｄ ｈｅａｌｔｈｙ ｃｏｎｔｒｏｌ' Ｈｕｍａｎ Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．６２， Ｎｏ．１１, 2001, ｐ．１２３９-４４ * |
| JPN6016009269; ＭＣＩＮＮＥＳ Ｉ． ｅｔ ａｌ．: 'Ａｎｔｉ-ｉｎｔｅｒｌｅｕｋｉｎ １７Ａ ｍｏｎｏｃｌｏｎａｌ ａｎｔｉｂｏｄｙ ｓｅｃｕｋｉｎｕｍａｂ ｒｅｄｕｃｅｓ ｓｉｇｎｓ ａｎｄ ｓｙｍｐｔｏｍｓ ｏｆ ｐｓｏｒｉａｔｉｃ ａｒｔｈｒｉｔ' Ａｒｔｈｒｉｔｉｓ ａｎｄ Ｒｈｅｕｍａｔｉｓｍ Ｖｏｌ．６３， Ｓｕｐｐｌ．１０, 201110, Ａｂｓｔｒａｃｔ Ｎｏ．７７９ * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140097178A (ko) | 2014-08-06 |
| AU2012341081B2 (en) | 2015-06-04 |
| BR112014012101A2 (pt) | 2019-09-24 |
| CA2856252A1 (en) | 2013-05-30 |
| RU2014125071A (ru) | 2015-12-27 |
| EP2783014A1 (en) | 2014-10-01 |
| AR086907A1 (es) | 2014-01-29 |
| WO2013077907A1 (en) | 2013-05-30 |
| MX2014006158A (es) | 2014-06-19 |
| AU2012341081A1 (en) | 2014-05-29 |
| US20150064193A1 (en) | 2015-03-05 |
| CN104011223A (zh) | 2014-08-27 |
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