JP2015504430A - Ｉｌ−７アンタゴニスト及びｐｓａ応答又は非応答対立遺伝子を用いた乾癬性関節炎（ｐｓａ）を治療する方法 - Google Patents

Ｉｌ−７アンタゴニスト及びｐｓａ応答又は非応答対立遺伝子を用いた乾癬性関節炎（ｐｓａ）を治療する方法 Download PDF

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JP2015504430A
JP2015504430A JP2014542299A JP2014542299A JP2015504430A JP 2015504430 A JP2015504430 A JP 2015504430A JP 2014542299 A JP2014542299 A JP 2014542299A JP 2014542299 A JP2014542299 A JP 2014542299A JP 2015504430 A JP2015504430 A JP 2015504430A
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ノバルティス アーゲー
ノバルティス アーゲー
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JP2014542299A 2011-11-21 2012-06-07 Ｉｌ−７アンタゴニスト及びｐｓａ応答又は非応答対立遺伝子を用いた乾癬性関節炎（ｐｓａ）を治療する方法 Pending JP2015504430A (ja)

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IQ370/2011 2011-11-21
IQ3702011 2011-11-21
US201261624564P 2012-04-16 2012-04-16
US61/624,564 2012-04-16
PCT/US2012/041310 WO2013077907A1 (en) 2011-11-21 2012-06-07 Methods of treating psoriatic arthritis (psa) using il-17 antagonists and psa response or non- response alleles

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JP2015504430A true JP2015504430A (ja) 2015-02-12
JP2015504430A5 JP2015504430A5 (enExample) 2015-07-23

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US (1) US20150064193A1 (enExample)
EP (1) EP2783014A1 (enExample)
JP (1) JP2015504430A (enExample)
KR (1) KR20140097178A (enExample)
CN (1) CN104011223A (enExample)
AR (1) AR086907A1 (enExample)
AU (1) AU2012341081B2 (enExample)
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MX (1) MX2014006158A (enExample)
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RU2665954C1 (ru) 2010-10-08 2018-09-05 Новартис Аг Способы лечения псориаза с использованием антагонистов il-17
TWI616204B (zh) 2010-11-05 2018-03-01 諾華公司 Ｉｌ-１７抗體用於製備治療牛皮癬性關節炎之藥物之用途
JP2014511687A (ja) 2011-03-31 2014-05-19 モデルナ セラピューティクス インコーポレイテッド 工学操作された核酸の送達および製剤
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EP2763701B1 (en) 2011-10-03 2018-12-19 Moderna Therapeutics, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
JP2015501844A (ja) 2011-12-16 2015-01-19 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 修飾ヌクレオシド、ヌクレオチドおよび核酸組成物
WO2013151663A1 (en) 2012-04-02 2013-10-10 modeRNA Therapeutics Modified polynucleotides for the production of membrane proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
ES2921623T3 (es) 2012-11-26 2022-08-30 Modernatx Inc ARN modificado terminalmente
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
KR20160067219A (ko) 2013-10-03 2016-06-13 모더나 세라퓨틱스, 인코포레이티드 저밀도 지단백질 수용체를 암호화하는 폴리뉴클레오타이드
CA2949236C (en) 2014-05-15 2023-06-13 Incube Labs, Llc Pharmaceutical compositions and methods for fabrication of solid masses comprising polypeptides and/or proteins
US11548940B2 (en) 2014-05-15 2023-01-10 Rani Therapeutics, Llc Anti-interleukin antibody preparations for delivery into a lumen of the intestinal tract using a swallowable drug delivery device
US11278618B2 (en) * 2014-09-10 2022-03-22 Novartis Ag Use of IL-17 antagonists to inhibit the progression of structural damage in psoriatic arthritis patients
AR103173A1 (es) 2014-12-22 2017-04-19 Novarits Ag Productos farmacéuticos y composiciones líquidas estables de anticuerpos il-17
AR103172A1 (es) * 2014-12-22 2017-04-19 Novartis Ag Reducción selectiva de residuos de cisteina en anticuerpos il-17
WO2016118921A1 (en) * 2015-01-24 2016-07-28 Abbvie, Inc. Compositions and methods for treating psoriatic arthritis
MY207225A (en) 2015-10-27 2025-02-06 UCB Biopharma SRL Methods of treatment using anti-il-17a/f antibodies
MX2021005905A (es) * 2018-11-20 2021-06-23 Janssen Biotech Inc Metodo seguro y eficaz para tratar la psoriasis con el anticuerpo especifico anti-il-23.
JP2022536088A (ja) * 2019-06-04 2022-08-12 ヤンセン バイオテツク，インコーポレーテツド 抗ｉｌ２３特異的抗体で乾癬性関節炎を治療する安全かつ有効な方法
CA3155108A1 (en) * 2019-09-20 2021-03-25 Novartis Ag Methods of treating autoimmune diseases using interleukin-17 (il-17) antagonists
AU2022232007A1 (en) * 2021-03-12 2023-10-26 Janssen Biotech, Inc. Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody
CA3212729A1 (en) * 2021-03-12 2022-09-15 Janssen Biotech, Inc. Safe and effective method of treating psoriatic arthritis with anti-il23 specific antibody
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JPN6016009265; ＬＡＭＢＥＲＴ　Ｓ．　ｅｔ　ａｌ．: 'ＴＲＡＦ３ＩＰ２　ｃｏｕｐｌｅｓ　ＩＬ-１７　ｔｏ　ｔｈｅ　ｅｐｉｄｅｒｍａｌ　ｄｅｆｅｎｓｅ　ｒｅｓｐｏｎｓｅ' Ｊｏｕｒｎａｌ　ｏｆ　Ｉｎｖｅｓｔｉｇａｔｉｖｅ　Ｄｅｒｍａｔｏｌｏｇｙ Ｖｏｌ．１３１，　Ｓｕｐｐｌ．１, 201104, ｐ．Ｓ６，　Ａｂｓｔｒａｃｔ　Ｎｏ．０３４ *
JPN6016009266; ＶＥＬＩＣＨＫＯ　Ｓ．　ｅｔ　ａｌ．: 'Ｇｌｏｂａｌ　ｇｅｎｅ　ｅｘｐｒｅｓｓｉｏｎ　ａｎａｌｙｓｉｓ　ｏｆ　Ａｃｔ１'ｓ　ｅｆｆｅｃｔｓ　ｉｎ　ａｉｒｗａｙ　ｅｐｉｔｈｅｌｉａｌ　ｃｅｌｌｓ' Ｊｏｕｒｎａｌ　ｏｆ　Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．１８６，　ＭｅｅｔｉｎｇＡｂｓｔｒａｃｔｓ, 201104, Ａｂｓｔｒａｃｔ　Ｎｏ．１６１．１７ *
JPN6016009267; ＥＬＬＩＮＧＨＡＵＳ　Ｅ．　ｅｔ　ａｌ．: 'Ｇｅｎｏｍｅ-ｗｉｄｅ　ａｓｓｏｃｉａｔｉｏｎ　ｓｔｕｄｙ　ｉｄｅｎｔｉｆｉｅｓ　ａ　ｐｓｏｒｉａｓｉｓ　ｓｕｓｃｅｐｔｉｂｉｌｉｔｙ　ｌｏｃｕｓ　ａｔ　ＴＲＡＦ３ＩＰ２' Ｎａｔｕｒｅ　Ｇｅｎｅｔｉｃｓ Ｖｏｌ．４２，　Ｎｏ．１１, 2010, ｐ．９９１-５ *
JPN6016009268; ＧＬＡＤＭＡＮ　Ｄ．Ｄ．　ｅｔ　ａｌ．: 'ＨＬＡ-ＤＲＢ１＊０４　ａｌｌｅｌｅｓ　ｉｎ　ｐｓｏｒｉａｔｉｃ　ａｒｔｈｒｉｔｉｓ：　ｃｏｍｐａｒｉｓｏｎ　ｗｉｔｈ　ｒｈｅｕｍａｔｏｉｄ　ａｒｔｈｒｉｔｉｓ　ａｎｄ　ｈｅａｌｔｈｙ　ｃｏｎｔｒｏｌ' Ｈｕｍａｎ　Ｉｍｍｕｎｏｌｏｇｙ Ｖｏｌ．６２，　Ｎｏ．１１, 2001, ｐ．１２３９-４４ *
JPN6016009269; ＭＣＩＮＮＥＳ　Ｉ．　ｅｔ　ａｌ．: 'Ａｎｔｉ-ｉｎｔｅｒｌｅｕｋｉｎ　１７Ａ　ｍｏｎｏｃｌｏｎａｌ　ａｎｔｉｂｏｄｙ　ｓｅｃｕｋｉｎｕｍａｂ　ｒｅｄｕｃｅｓ　ｓｉｇｎｓ　ａｎｄ　ｓｙｍｐｔｏｍｓ　ｏｆ　ｐｓｏｒｉａｔｉｃ　ａｒｔｈｒｉｔ' Ａｒｔｈｒｉｔｉｓ　ａｎｄ　Ｒｈｅｕｍａｔｉｓｍ Ｖｏｌ．６３，　Ｓｕｐｐｌ．１０, 201110, Ａｂｓｔｒａｃｔ　Ｎｏ．７７９ *

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MX2014006158A (es) 2014-06-19
WO2013077907A1 (en) 2013-05-30
EP2783014A1 (en) 2014-10-01
BR112014012101A2 (pt) 2019-09-24
CA2856252A1 (en) 2013-05-30
AR086907A1 (es) 2014-01-29
AU2012341081A1 (en) 2014-05-29
US20150064193A1 (en) 2015-03-05
CN104011223A (zh) 2014-08-27
RU2014125071A (ru) 2015-12-27
AU2012341081B2 (en) 2015-06-04
KR20140097178A (ko) 2014-08-06

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