JP2015502367A5 - - Google Patents
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- Publication number
- JP2015502367A5 JP2015502367A5 JP2014547550A JP2014547550A JP2015502367A5 JP 2015502367 A5 JP2015502367 A5 JP 2015502367A5 JP 2014547550 A JP2014547550 A JP 2014547550A JP 2014547550 A JP2014547550 A JP 2014547550A JP 2015502367 A5 JP2015502367 A5 JP 2015502367A5
- Authority
- JP
- Japan
- Prior art keywords
- group
- phenyl
- compound
- cancer
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161576780P | 2011-12-16 | 2011-12-16 | |
| US61/576,780 | 2011-12-16 | ||
| PCT/US2012/070155 WO2013090912A1 (en) | 2011-12-16 | 2012-12-17 | Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017102107A Division JP6726640B2 (ja) | 2011-12-16 | 2017-05-23 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015502367A JP2015502367A (ja) | 2015-01-22 |
| JP2015502367A5 true JP2015502367A5 (cg-RX-API-DMAC10.html) | 2016-02-25 |
| JP6463130B2 JP6463130B2 (ja) | 2019-01-30 |
Family
ID=47436279
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014547550A Active JP6463130B2 (ja) | 2011-12-16 | 2012-12-17 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
| JP2017102107A Active JP6726640B2 (ja) | 2011-12-16 | 2017-05-23 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2017102107A Active JP6726640B2 (ja) | 2011-12-16 | 2017-05-23 | 腫瘍転移及び腫瘍形成の予防及び治療のための化合物並びに方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US9663521B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2791142B1 (cg-RX-API-DMAC10.html) |
| JP (2) | JP6463130B2 (cg-RX-API-DMAC10.html) |
| AU (2) | AU2012353651B2 (cg-RX-API-DMAC10.html) |
| CA (1) | CA2859370C (cg-RX-API-DMAC10.html) |
| ES (1) | ES2748590T3 (cg-RX-API-DMAC10.html) |
| WO (1) | WO2013090912A1 (cg-RX-API-DMAC10.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9663521B2 (en) * | 2011-12-16 | 2017-05-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis |
| CA2957046C (en) * | 2014-08-04 | 2022-11-15 | Nuevolution A/S | Optionally fused heterocyclyl-substituted derivatives of pyrimidine useful for the treatment of inflammatory, metabolic, oncologic and autoimmune diseases |
| US9877966B1 (en) * | 2015-08-10 | 2018-01-30 | Eugene J. Oliva | Combination therapy for the inhibition of metastasis and tumorigenesis |
| WO2018140630A1 (en) * | 2017-01-25 | 2018-08-02 | Northwestern University | Autophagy inducers for treatment of cns conditions |
| JP7421499B2 (ja) * | 2018-05-15 | 2024-01-24 | アメリカ合衆国 | 腫瘍転移および腫瘍発生の予防および治療のための製剤および方法 |
| WO2021124277A1 (en) | 2019-12-20 | 2021-06-24 | Nuevolution A/S | Compounds active towards nuclear receptors |
| US11685727B2 (en) | 2019-12-20 | 2023-06-27 | Nuevolution A/S | Compounds active towards nuclear receptors |
| EP4126874A1 (en) | 2020-03-31 | 2023-02-08 | Nuevolution A/S | Compounds active towards nuclear receptors |
| AU2021249530A1 (en) | 2020-03-31 | 2022-12-01 | Nuevolution A/S | Compounds active towards nuclear receptors |
| US20260028342A1 (en) * | 2022-07-29 | 2026-01-29 | The University Of North Carolina At Chapel Hill | Enhancing antimetastasis activity using targeted protein degradation |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4235871A (en) | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
| US4501728A (en) | 1983-01-06 | 1985-02-26 | Technology Unlimited, Inc. | Masking of liposomes from RES recognition |
| US5019369A (en) | 1984-10-22 | 1991-05-28 | Vestar, Inc. | Method of targeting tumors in humans |
| US4837028A (en) | 1986-12-24 | 1989-06-06 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
| IL112249A (en) | 1994-01-25 | 2001-11-25 | Warner Lambert Co | Pharmaceutical compositions containing di and tricyclic pyrimidine derivatives for inhibiting tyrosine kinases of the epidermal growth factor receptor family and some new such compounds |
| GB9604361D0 (en) | 1996-02-29 | 1996-05-01 | Pharmacia Spa | 4-Substituted pyrrolopyrimidine compounds as tyrosine kinase inhibitors |
| US7863444B2 (en) | 1997-03-19 | 2011-01-04 | Abbott Laboratories | 4-aminopyrrolopyrimidines as kinase inhibitors |
| US6664252B2 (en) | 1999-12-02 | 2003-12-16 | Osi Pharmaceuticals, Inc. | 4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof |
| US20030114467A1 (en) | 2001-06-21 | 2003-06-19 | Shakespeare William C. | Novel pyrazolo- and pyrrolo-pyrimidines and uses thereof |
| EP2190466A4 (en) | 2007-08-10 | 2011-12-21 | Burnham Inst Medical Research | Tissue-specific alkaline phosphatase (TNAP) activators and their use |
| US8642660B2 (en) * | 2007-12-21 | 2014-02-04 | The University Of Rochester | Method for altering the lifespan of eukaryotic organisms |
| US9101635B2 (en) * | 2009-07-10 | 2015-08-11 | Microbiotix, Inc. | Inhibitors of filovirus entry into host cells |
| US9663521B2 (en) * | 2011-12-16 | 2017-05-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Compounds and methods for the prevention and treatment of tumor metastasis and tumorigenesis |
| JP6681070B2 (ja) * | 2015-11-19 | 2020-04-15 | 国立大学法人 岡山大学 | 光ファイバ装置及びセンサシステム |
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2012
- 2012-12-17 US US14/364,759 patent/US9663521B2/en active Active
- 2012-12-17 JP JP2014547550A patent/JP6463130B2/ja active Active
- 2012-12-17 AU AU2012353651A patent/AU2012353651B2/en active Active
- 2012-12-17 EP EP12806846.7A patent/EP2791142B1/en active Active
- 2012-12-17 ES ES12806846T patent/ES2748590T3/es active Active
- 2012-12-17 CA CA2859370A patent/CA2859370C/en active Active
- 2012-12-17 WO PCT/US2012/070155 patent/WO2013090912A1/en not_active Ceased
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2017
- 2017-05-23 JP JP2017102107A patent/JP6726640B2/ja active Active
- 2017-05-26 US US15/606,740 patent/US10301314B2/en active Active
- 2017-12-13 AU AU2017276258A patent/AU2017276258B2/en active Active