JP2015209424A5 - - Google Patents
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- Publication number
- JP2015209424A5 JP2015209424A5 JP2014095457A JP2014095457A JP2015209424A5 JP 2015209424 A5 JP2015209424 A5 JP 2015209424A5 JP 2014095457 A JP2014095457 A JP 2014095457A JP 2014095457 A JP2014095457 A JP 2014095457A JP 2015209424 A5 JP2015209424 A5 JP 2015209424A5
- Authority
- JP
- Japan
- Prior art keywords
- composition
- density lipoprotein
- concentration
- calebin
- oral administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000203 mixture Substances 0.000 claims 8
- 241000124008 Mammalia Species 0.000 claims 7
- UYEWRTKHKAVRDI-UHFFFAOYSA-N Calebin A Natural products C1=C(O)C(OC)=CC(C=CC(=O)COC(=O)C=CC=2C=C(OC)C(O)=CC=2)=C1 UYEWRTKHKAVRDI-UHFFFAOYSA-N 0.000 claims 5
- UYEWRTKHKAVRDI-ASVGJQBISA-N Calebin A Chemical compound C1=C(O)C(OC)=CC(\C=C\C(=O)COC(=O)\C=C\C=2C=C(OC)C(O)=CC=2)=C1 UYEWRTKHKAVRDI-ASVGJQBISA-N 0.000 claims 5
- 108010010234 HDL Lipoproteins Proteins 0.000 claims 4
- 102000015779 HDL Lipoproteins Human genes 0.000 claims 4
- 108010007622 LDL Lipoproteins Proteins 0.000 claims 4
- 102000007330 LDL Lipoproteins Human genes 0.000 claims 4
- 108010062497 VLDL Lipoproteins Proteins 0.000 claims 4
- 210000004369 blood Anatomy 0.000 claims 3
- 239000008280 blood Substances 0.000 claims 3
- 208000035150 Hypercholesterolemia Diseases 0.000 claims 2
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 2
- 210000002966 serum Anatomy 0.000 claims 2
- UFTFJSFQGQCHQW-UHFFFAOYSA-N triformin Chemical compound O=COCC(OC=O)COC=O UFTFJSFQGQCHQW-UHFFFAOYSA-N 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 1
- 208000004930 Fatty Liver Diseases 0.000 claims 1
- 206010019708 Hepatic steatosis Diseases 0.000 claims 1
- 206010033645 Pancreatitis Diseases 0.000 claims 1
- 235000012000 cholesterol Nutrition 0.000 claims 1
- 230000007423 decrease Effects 0.000 claims 1
- 208000010706 fatty liver disease Diseases 0.000 claims 1
- 208000006575 hypertriglyceridemia Diseases 0.000 claims 1
- 230000002265 prevention Effects 0.000 claims 1
- 231100000240 steatosis hepatitis Toxicity 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US14/259,404 | 2014-04-23 | ||
| US14/259,404 US9668999B2 (en) | 2014-04-23 | 2014-04-23 | Method for the treatment of hypercholesterolemia |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2015209424A JP2015209424A (ja) | 2015-11-24 |
| JP2015209424A5 true JP2015209424A5 (enExample) | 2016-06-16 |
| JP6263707B2 JP6263707B2 (ja) | 2018-01-24 |
Family
ID=50828681
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014095457A Expired - Fee Related JP6263707B2 (ja) | 2014-04-23 | 2014-05-02 | 高コレステロール血症の治療方法 |
Country Status (11)
| Country | Link |
|---|---|
| US (2) | US9668999B2 (enExample) |
| EP (1) | EP2937084B1 (enExample) |
| JP (1) | JP6263707B2 (enExample) |
| KR (1) | KR101647549B1 (enExample) |
| AU (1) | AU2014202312B2 (enExample) |
| CA (2) | CA2850999C (enExample) |
| EA (1) | EA027148B1 (enExample) |
| MY (1) | MY170067A (enExample) |
| PH (1) | PH12014000244A1 (enExample) |
| PL (1) | PL2937084T3 (enExample) |
| TW (1) | TWI622394B (enExample) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SG10201503805XA (en) * | 2015-04-19 | 2016-11-29 | Sabinsa Corp | Calebin A For Hepatic Steatosis |
| US9539232B1 (en) * | 2016-08-04 | 2017-01-10 | Muhammed Majeed | Calebin A for osteoporosis |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1060352C (zh) * | 1996-02-08 | 2001-01-10 | 袁克兴 | 降脂药及其制备方法 |
| US6811786B1 (en) * | 1999-04-01 | 2004-11-02 | Ganeden Biotech, Inc. | Methods for reducing cholesterol using Bacillus coagulans spores, systems and compositions |
| WO2001030335A2 (en) * | 1999-10-22 | 2001-05-03 | The Board Of Trustees Of The University Of Illinois | Pharmaceutical compositions useful in the prevention and treatment of beta-amyloid protein-induced disease |
| US20020012733A1 (en) | 2000-04-12 | 2002-01-31 | The Procter & Gamble Company | Compositions for reducing hypercholesterolemia and controlling of postprandial blood glucose and insulin levels |
| JP2005232059A (ja) * | 2004-02-18 | 2005-09-02 | Iichiro Shimomura | 低アディポネクチン血症予防・治療剤 |
| JP4834824B2 (ja) * | 2004-07-08 | 2011-12-14 | 独立行政法人産業技術総合研究所 | アディポネクチン産生増強剤 |
| JP2010018522A (ja) * | 2007-03-23 | 2010-01-28 | Hiroshima Univ | アディポネクチン産生促進剤 |
| JP5294165B2 (ja) * | 2007-03-23 | 2013-09-18 | ナガセケムテックス株式会社 | アディポネクチン上昇剤 |
| CN101301455A (zh) * | 2008-07-01 | 2008-11-12 | 崔井朝 | 一种治疗高脂血症的中药复方姜黄固体分散体 |
| JP2011063543A (ja) * | 2009-09-17 | 2011-03-31 | Kao Corp | アディポネクチン増加剤 |
| KR101702702B1 (ko) * | 2011-01-10 | 2017-02-03 | 무하메드 마제에드 | 칼레빈 ａ의 항-비만 가능성 |
-
2014
- 2014-04-23 US US14/259,404 patent/US9668999B2/en active Active
- 2014-04-29 AU AU2014202312A patent/AU2014202312B2/en not_active Ceased
- 2014-05-01 CA CA2850999A patent/CA2850999C/en active Active
- 2014-05-01 CA CA2963383A patent/CA2963383C/en active Active
- 2014-05-02 JP JP2014095457A patent/JP6263707B2/ja not_active Expired - Fee Related
- 2014-05-08 PL PL14167512T patent/PL2937084T3/pl unknown
- 2014-05-08 EP EP14167512.4A patent/EP2937084B1/en active Active
- 2014-06-10 KR KR1020140070179A patent/KR101647549B1/ko not_active Expired - Fee Related
- 2014-07-25 MY MYPI2014002207A patent/MY170067A/en unknown
- 2014-08-26 PH PH12014000244A patent/PH12014000244A1/en unknown
- 2014-09-03 TW TW103130375A patent/TWI622394B/zh not_active IP Right Cessation
- 2014-09-17 EA EA201491545A patent/EA027148B1/ru unknown
-
2015
- 2015-03-03 US US14/637,081 patent/US9610273B2/en active Active
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