JP2014534263A5 - - Google Patents
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- Publication number
- JP2014534263A5 JP2014534263A5 JP2014543579A JP2014543579A JP2014534263A5 JP 2014534263 A5 JP2014534263 A5 JP 2014534263A5 JP 2014543579 A JP2014543579 A JP 2014543579A JP 2014543579 A JP2014543579 A JP 2014543579A JP 2014534263 A5 JP2014534263 A5 JP 2014534263A5
- Authority
- JP
- Japan
- Prior art keywords
- serine
- day
- derivative
- pharmaceutical composition
- precursor
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161562194P | 2011-11-21 | 2011-11-21 | |
| US61/562,194 | 2011-11-21 | ||
| PCT/US2012/066373 WO2013078395A1 (en) | 2011-11-21 | 2012-11-21 | L-serine compositions, methods and uses for treating neurodegenerative diseases and disorders |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014534263A JP2014534263A (ja) | 2014-12-18 |
| JP2014534263A5 true JP2014534263A5 (https=) | 2016-01-07 |
| JP6265908B2 JP6265908B2 (ja) | 2018-01-24 |
Family
ID=48470319
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014543579A Active JP6265908B2 (ja) | 2011-11-21 | 2012-11-21 | 神経変性疾患および障害を処置するためのｌ−セリン組成物、方法および使用 |
Country Status (10)
| Country | Link |
|---|---|
| US (5) | US20130156846A1 (https=) |
| EP (1) | EP2782566B1 (https=) |
| JP (1) | JP6265908B2 (https=) |
| AU (1) | AU2012340563B2 (https=) |
| CA (1) | CA2855854C (https=) |
| DK (1) | DK2782566T3 (https=) |
| ES (1) | ES2856063T3 (https=) |
| IL (1) | IL232710B (https=) |
| PT (1) | PT2782566T (https=) |
| WO (1) | WO2013078395A1 (https=) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MX2017006748A (es) * | 2014-11-24 | 2017-08-28 | Entrinsic Health Solutions Inc | Composiciones de aminoácidos para el tratamiento de síntomas de enfermedades. |
| US10960076B2 (en) | 2017-01-25 | 2021-03-30 | Church & Dwight Co. Inc. | Gummy dosage forms comprising serine |
| KR20180101242A (ko) | 2017-03-02 | 2018-09-12 | 주식회사 아스트로젠 | 엘세린을 유효성분으로 포함하는 혈뇌장벽 장애의 예방 또는 치료용 약학적 조성물 및 건강 기능 식품 |
| AU2019282362B2 (en) * | 2018-06-08 | 2025-04-03 | The Institute For Ethnomedicine | Method of enhancing glucose levels in the central nervous system |
| KR101952443B1 (ko) * | 2018-08-23 | 2019-02-26 | 주식회사 아스트로젠 | 신규한 마그네슘세리네이트 화합물 및 이의 용도 |
| KR102022118B1 (ko) * | 2019-01-07 | 2019-09-18 | 주식회사 아스트로젠 | 중추신경계 질환의 예방 또는 치료용 세린 유도체 화합물 |
| AU2020334128B2 (en) * | 2019-08-21 | 2025-10-23 | Brain Chemistry Labs | Compositions comprising a metal and L-serine, and uses thereof |
| US12578348B2 (en) * | 2021-02-05 | 2026-03-17 | The Institute For Ethnomedicine | Blood indicators of Alzheimer's disease |
| CN112972458B (zh) * | 2021-03-05 | 2022-10-04 | 北京北科华夏生物医药科技有限公司 | 一种组合物在制备阿尔兹海默症治疗药物中的应用 |
| KR102522508B1 (ko) * | 2022-12-16 | 2023-04-18 | 주식회사 아스트로젠 | 마그네슘-세리네이트의 신규한 결정형 및 이의 제조방법 |
| WO2025014008A1 (ko) * | 2023-07-07 | 2025-01-16 | 주식회사 아스트로젠 | 질환의 치료 방법 |
| KR20250081156A (ko) * | 2023-11-29 | 2025-06-05 | 주식회사 아스트로젠 | L-세린 염산염의 제조 방법 및 이의 용도 |
| CN118303636A (zh) * | 2024-04-12 | 2024-07-09 | 南通大学 | 一种改善帕金森症状的功能性食品 |
| KR20260010331A (ko) * | 2024-07-12 | 2026-01-20 | 주식회사 아스트로젠 | L-세린의 리포좀 제형 및 이의 제조 방법 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3873722A (en) | 1974-05-31 | 1975-03-25 | Nelson Res & Dev | Method for treating schizophrenia |
| US4000318A (en) * | 1974-08-19 | 1976-12-28 | Commonwealth Scientific And Industrial Research Organization | Amino acid supplements |
| US4491589A (en) * | 1982-05-17 | 1985-01-01 | The Trustees Of Columbia University In The City Of New York | Amino acid solutions for parenteral nutrition and methods of formulation and use |
| US4522811A (en) | 1982-07-08 | 1985-06-11 | Syntex (U.S.A.) Inc. | Serial injection of muramyldipeptides and liposomes enhances the anti-infective activity of muramyldipeptides |
| SE8701662L (sv) * | 1987-04-22 | 1988-10-23 | Gelder Nico M Van | Saett och medel foer att behandla neurologiska sjukdomar, exempelvis migraen genom paaverkan av nervcellerna |
| JPS6440453A (en) | 1987-08-05 | 1989-02-10 | Mitsui Toatsu Chemicals | Racemization of optically active serine |
| US5668117A (en) | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| SE502280C2 (sv) | 1991-12-20 | 1995-09-25 | Bio Swede Ab | Separering av aminosyror, aminosyrabaserad monomer och förfarande för framställning därav samt polymert material och förfarande för framställning därav |
| WO1996015788A1 (en) | 1994-11-23 | 1996-05-30 | G.D. Searle & Co. | Use of amino-isoxazolidone compounds for improvement of implicit memory |
| CA2298795A1 (en) * | 1997-07-28 | 1999-02-04 | The Institute Of Physical And Chemical Research | Agent for protecting central nerve cells and enhancing survival thereof |
| EP1073432B1 (en) | 1998-04-14 | 2007-08-15 | The General Hospital Corporation | Use of d-serine or d-alanine for treating schizophrenia |
| US6984484B1 (en) * | 1999-01-19 | 2006-01-10 | The Johns Hopkins University | Mammalian serine racemase |
| JP2002316929A (ja) * | 2001-04-18 | 2002-10-31 | Japan Science & Technology Corp | Ｌ−セリン又はグリシンからなる抗アポトーシス剤 |
| WO2004000297A1 (en) * | 2002-06-19 | 2003-12-31 | N.V. Nutricia | Nutritional or pharmaceutical compositions for increasing the creatine response of organisms |
| JP2004182705A (ja) * | 2002-10-11 | 2004-07-02 | Yasutoshi Koga | ミトコンドリア機能異常に起因する疾患における臨床症状発現の予防・治療用組成物 |
| US20050028720A1 (en) * | 2003-08-05 | 2005-02-10 | Bell Adam Warwick | Pop-up device for deterring an attacking animal such as a bear |
| US7256002B2 (en) | 2003-08-12 | 2007-08-14 | The Institute For Ethnomedicine | Screening for neurotoxic amino acid associated with neurological disorders |
| US7148192B2 (en) | 2004-01-29 | 2006-12-12 | Ebwe Pharma Ges. M.H. Nfg.Kg | Neuroprotective dietary supplement |
| FI121915B (fi) | 2004-02-06 | 2011-06-15 | Neurofood Ab Oy | Koostumus psoriasiksen hoitoon |
| US20080027088A1 (en) | 2004-03-26 | 2008-01-31 | Warner-Lambert Company, Llc | Imidazole-Based Hmg-Coa Reductase Inhibitors |
| CA2583947A1 (en) | 2004-10-12 | 2006-04-20 | Forbes Medi-Tech (Research) Inc. | Compounds and methods of treating insulin resistance and cardiomyopathy |
| US20070286909A1 (en) * | 2006-06-07 | 2007-12-13 | Daniel S. Smith | Amino acid compositions |
| US20080058395A1 (en) | 2006-06-30 | 2008-03-06 | Sepracor Inc. | Fused heterocyclic inhibitors of D-amino acid oxidase |
| WO2008118785A2 (en) | 2007-03-23 | 2008-10-02 | Tikvah Therapeutics | Methods for treating depression using immediate-impact treatments and d-cycloserine |
| US20080241121A1 (en) | 2007-04-02 | 2008-10-02 | Daniela Salvemini | Inhibitors of the ceramide metabolic pathway as adjuncts to opiates for pain |
| EP2677319B1 (en) * | 2008-07-09 | 2015-12-30 | The Institute for Ethnomedicine | Antibody for detection of a neurotoxic amino acids associated with neurological disorders |
| WO2010132128A1 (en) * | 2009-05-14 | 2010-11-18 | The Board Of Trustees Of The Leland Stanford Junior University | Method of improving cognitve functions in individuals with down syndrome and/or alzheimer's disease |
| WO2011104298A1 (en) * | 2010-02-24 | 2011-09-01 | Universität Zürich | Prevention and treatment of diseases caused by elevated levels of deoxy-sphingolipids |
-
2012
- 2012-11-21 EP EP12851576.4A patent/EP2782566B1/en active Active
- 2012-11-21 AU AU2012340563A patent/AU2012340563B2/en active Active
- 2012-11-21 CA CA2855854A patent/CA2855854C/en active Active
- 2012-11-21 ES ES12851576T patent/ES2856063T3/es active Active
- 2012-11-21 DK DK12851576.4T patent/DK2782566T3/da active
- 2012-11-21 JP JP2014543579A patent/JP6265908B2/ja active Active
- 2012-11-21 US US13/683,821 patent/US20130156846A1/en not_active Abandoned
- 2012-11-21 PT PT128515764T patent/PT2782566T/pt unknown
- 2012-11-21 WO PCT/US2012/066373 patent/WO2013078395A1/en not_active Ceased
-
2014
- 2014-03-28 US US14/229,624 patent/US11917986B2/en active Active
- 2014-05-20 IL IL232710A patent/IL232710B/en unknown
-
2017
- 2017-10-06 US US15/727,335 patent/US11700840B2/en active Active
-
2021
- 2021-02-02 US US17/165,897 patent/US12295353B2/en active Active
- 2021-07-12 US US17/373,434 patent/US11974551B2/en active Active
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