JP2014529395A5 - - Google Patents
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- JP2014529395A5 JP2014529395A5 JP2014523291A JP2014523291A JP2014529395A5 JP 2014529395 A5 JP2014529395 A5 JP 2014529395A5 JP 2014523291 A JP2014523291 A JP 2014523291A JP 2014523291 A JP2014523291 A JP 2014523291A JP 2014529395 A5 JP2014529395 A5 JP 2014529395A5
- Authority
- JP
- Japan
- Prior art keywords
- dystonia
- syndrome
- disease
- polynucleotide
- modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 208000014094 Dystonic disease Diseases 0.000 claims description 68
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- 239000002157 polynucleotide Substances 0.000 claims description 30
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims description 18
- 208000004350 Strabismus Diseases 0.000 claims description 16
- 229920001184 polypeptide Polymers 0.000 claims description 14
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 14
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161574596P | 2011-08-04 | 2011-08-04 | |
| EP11176531.9 | 2011-08-04 | ||
| EP11176531 | 2011-08-04 | ||
| US61/574,596 | 2011-08-04 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014529395A JP2014529395A (ja) | 2014-11-13 |
| JP2014529395A5 true JP2014529395A5 (OSRAM) | 2016-07-28 |
Family
ID=47628649
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014523291A Pending JP2014529395A (ja) | 2011-08-04 | 2012-07-26 | ボツリヌス神経毒のタンパク質分解的切断の改変 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20140170133A1 (OSRAM) |
| EP (1) | EP2739297A1 (OSRAM) |
| JP (1) | JP2014529395A (OSRAM) |
| AU (1) | AU2012292163A1 (OSRAM) |
| CA (1) | CA2841933A1 (OSRAM) |
| WO (1) | WO2013017522A1 (OSRAM) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3290437A1 (en) | 2016-08-31 | 2018-03-07 | Merz Pharma GmbH & Co. KGaA | Novel recombinant clostridial neurotoxins with decreased duration of effect |
| EP3312193A1 (en) | 2016-10-19 | 2018-04-25 | Merz Pharma GmbH & Co. KGaA | Novel recombinant botulinum neurotoxins with accelerated onset of effect |
| WO2018081282A1 (en) * | 2016-10-25 | 2018-05-03 | Cellsnap Llc | Neurotoxins and uses thereof |
| EP3335719A1 (en) * | 2016-12-14 | 2018-06-20 | Merz Pharma GmbH & Co. KGaA | Novel recombinant botulinum neurotoxins with a stabilized light chain |
| CN118126143B (zh) * | 2024-03-14 | 2025-06-24 | 河北平朴生物科技合伙企业(有限合伙) | 一种a型肉毒毒素的突变体及其应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5939070A (en) * | 1996-10-28 | 1999-08-17 | Wisconsin Alumni Research Foundation | Hybrid botulinal neurotoxins |
| US6903187B1 (en) * | 2000-07-21 | 2005-06-07 | Allergan, Inc. | Leucine-based motif and clostridial neurotoxins |
| US20030219462A1 (en) * | 2000-07-21 | 2003-11-27 | Allergan Sales, Inc | Clostridial neurotoxin compositions and modified clostridial neurotoxins |
| US6943555B2 (en) * | 2002-05-23 | 2005-09-13 | Lockheed Martin Corporation | Redundant safety circuit for squib testing |
| MX2011001823A (es) * | 2008-08-29 | 2011-03-25 | Merz Pharma Gmbh & Co Kgaa | Neurotoxinas clostridiales con persistencia alterada. |
| GB0903006D0 (en) * | 2009-02-23 | 2009-04-08 | Syntaxin Ltd | Modified non-cytotoxic proteases |
-
2012
- 2012-07-26 AU AU2012292163A patent/AU2012292163A1/en not_active Abandoned
- 2012-07-26 WO PCT/EP2012/064690 patent/WO2013017522A1/en not_active Ceased
- 2012-07-26 CA CA2841933A patent/CA2841933A1/en not_active Abandoned
- 2012-07-26 JP JP2014523291A patent/JP2014529395A/ja active Pending
- 2012-07-26 US US14/236,454 patent/US20140170133A1/en not_active Abandoned
- 2012-07-26 EP EP12742873.8A patent/EP2739297A1/en not_active Withdrawn
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