JP2014528800A - 組織の活動の感知又は刺激 - Google Patents
組織の活動の感知又は刺激 Download PDFInfo
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- JP2014528800A JP2014528800A JP2014533737A JP2014533737A JP2014528800A JP 2014528800 A JP2014528800 A JP 2014528800A JP 2014533737 A JP2014533737 A JP 2014533737A JP 2014533737 A JP2014533737 A JP 2014533737A JP 2014528800 A JP2014528800 A JP 2014528800A
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- intravascular device
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- neural tissue
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Abstract
Description
Claims (44)
- 神経組織の活動の感知又は刺激のうち少なくとも一方を行うためのシステムであって、
動物の血管内に配置するための血管内デバイスを備え、
前記血管内デバイスは、その付近の前記血管の外に位置する神経組織の活動の感知又は刺激のうち少なくとも一方に適している、システム。 - 前記血管内デバイスは電極を備え、前記電極はその付近の前記血管の外に位置する神経組織の活動の感知又は刺激のうち少なくとも一方を行うための電極である、請求項1に記載のシステム。
- 感知又は刺激のうち少なくとも一方の対象となる前記神経組織付近の前記血管内の領域にて、前記血管内デバイスを保持するための保持部材を備えた、請求項1又は2に記載のシステム。
- 前記保持部材は、前記血管内での拡張に適した、請求項3に記載のシステム。
- 前記保持部材は、体内への配置及び体内での漸次的な分解に適した、請求項3又は4に記載のシステム。
- 前記保持部材は、前記血管内での長期間配置に適した、請求項3又は4に記載のシステム。
- 前記保持部材は、前記血管内の領域での配置、回収、及び前記血管内の異なる領域へのその後の再配置に適した、請求項3〜6のうちいずれか一項に記載のシステム。
- 前記保持部材は、ステントを備える、請求項3〜7のうちいずれか一項に記載のシステム。
- 前記保持部材は、プローブを備える、請求項3〜8のうちいずれか一項に記載のシステム。
- 前記プローブは、細長い可撓性マイクロチューブを備えた、請求項9に記載のシステム。
- 前記血管内デバイスは、前記プローブに取り付けられており、前記プローブは前記血管内デバイスとの間の電気信号の伝導に適した、請求項9又は10に記載のシステム。
- 前記血管内デバイスとの間で送受信した信号を処理するためのプロセッサを備えた、請求項1〜11のうちいずれか一項に記載のシステム。
- 前記血管内デバイスとの間で、データと電力のうち少なくとも一方を、ワイヤレスで送受信するためのワイヤレス送受信システムを備えた、請求項1〜12のうちいずれか一項に記載のシステム。
- 前記ワイヤレス送受信システムは、磁気誘導コイルとRF送受信装置のうち少なくとも1つを備えた、請求項13に記載のシステム。
- 感知された神経組織の活動が、所定のパラメータ範囲を外れると警報信号を送信するのに適した警報システムを備えた、請求項1〜14のうちいずれか一項に記載のシステム。
- 前記警報は、感知された活動が、前記動物に起こり得る、発作が差し迫った状態を示したときに発する警告信号を含む、請求項15に記載のシステム。
- 前記動物の血管に通し、前記動物の前記血管内を通過させられるように適合させた案内部材を備え、
前記案内部材は、感知又は刺激のうち少なくとも一方の対象となる前記神経組織付近の前記血管内の領域へと前記血管内デバイスを案内するのに適している、請求項1〜16のうちいずれか一項に記載のシステム。 - 前記案内部材は、その内部に前記血管内デバイスを通過させるのに適した、請求項17に記載のシステム。
- 前記血管内デバイスと離れて配置されたデバイスを備え、前記デバイスは、データ又は電力の保存、処理、及び前記血管内デバイスとの間の送受信のうち少なくとも1つに適している、請求項1〜18のうちいずれか一項に記載のシステム。
- 前記デバイスは、データ及び電力のうち少なくとも一方を、前記血管内デバイスと前記デバイスとの間、又は2つの前記デバイス間で送受信するためのワイヤレス送受信機構を備えた、請求項19に記載のシステム。
- 前記デバイスは、血管内配置に適した内部ユニットを備えた、請求項19又は20に記載のシステム。
- 前記デバイスは、皮下配置に適した内部ユニットを備えた、請求項19〜21のうちいずれか一項に記載のシステム。
- 前記デバイスは、体への配置又は体外の配置に適した外部ユニットを備えた、請求項19又は20に記載のシステム。
- 前記デバイスは、義肢を備えた、請求項19又は20に記載のシステム。
- 動物の、1つ以上の血管におけるさまざまな領域にて保持するのに適した複数の血管内デバイスを備えることで、前記血管内デバイス付近のさまざまな領域の神経組織における電気的活動の感知又は刺激のうち少なくとも一方を可能にする、請求項1〜24のうちいずれか一項に記載のシステム。
- 動物の血管内で神経組織の電気的活動を感知又は刺激するための方法であって、
動物の、神経組織付近の血管内で神経組織の電気的活動の感知又は刺激のうち少なくとも一方を行うのに血管内デバイスを用いることを含む、方法。 - 感知又は刺激の対象となる前記神経組織付近の前記血管内の領域へと、前記血管内デバイスを案内することを含む、請求項26に記載の方法。
- 前記血管の内壁に対して前記血管内デバイスを保持することを含む、請求項26又は27に記載の方法。
- 内側血管壁に対して前記血管内デバイスを保持するために、前記血管内で保持部材を拡張することを含む、請求項26〜28のうちいずれか一項に記載の方法。
- 感知された、前記神経組織の活動に基いて、血管内脳波の信号を生成することを含む、請求項26〜29のうちいずれか一項に記載の方法。
- 前記血管内デバイスと、信号を保存、処理、又は前記デバイスとの間で送受信するのに適した別個のデバイスと、の間でデータ又は電力をワイヤレスで送受信することを含む、請求項26〜30のうちいずれか一項に記載の方法。
- 1つ以上の血管のさまざまな領域内に配置された、複数の血管内デバイスによって、神経組織の複数領域における電気的活動を感知又は刺激することを含む、請求項26〜31のうちいずれか一項に記載の方法。
- 動物の、脳深部領域付近の血管内に前記血管内デバイスを保持又は配置することと、血管内で脳深部領域の電気的活動を感知又は刺激することとを含む、請求項26〜32のうちいずれか一項に記載の方法。
- パーキンソン病、うつ病、強迫性障害、又はトゥレット症候群等の医的障害の治療のために、神経組織を血管内で刺激することを含む、請求項26〜33のうちいずれか一項に記載の方法。
- 前記神経組織付近に配置されたときに、前記血管内デバイスが感知した信号に基いて、神経組織の性状をマッピングすることを含む、請求項26〜34のうちいずれか一項に記載の方法。
- 前記血管内デバイス付近の前記神経組織を刺激するために、内部デバイス又は外部デバイスから前記血管内デバイスへと信号を送信することを含む、請求項26〜35のうちいずれか一項に記載の方法。
- 前記内部デバイス又は前記外部デバイスを作動させるために、前記血管内デバイスが感知した電気的信号に基いて、前記内部デバイス又は前記外部デバイスへと信号を送信することを含む、請求項26〜36のうちいずれか一項に記載の方法。
- 義肢を運動させるために、前記血管内デバイスが感知した電気的信号に基いて、前記義肢へと信号を送信することを含む、請求項26〜37のうちいずれか一項に記載の方法。
- 前記血管内デバイスは、脳の中心後回にわたって又は沿って延びる中大脳動脈の第2分岐又は第3分岐に保持又は配置される、請求項26〜38のうちいずれか一項に記載の方法。
- 感知された電気的活動をモニタリングすることで、てんかん発作又は発作焦点を検知することを含む、請求項26〜39のうちいずれか一項に記載の方法。
- 差し迫った発作の前兆を検出するために、海馬の血管に広がる部分に前記血管内デバイスを保持又は配置することを含む、請求項26〜40のうちいずれか一項に記載の方法。
- 正常な体部位、失われた体部位又は人工的な体部位の運動を試みることによって、中心前回における電気的活動の変化を感知することを含む、請求項26〜41のうちいずれか一項に記載の方法。
- 血管内で前記中心前回を刺激することによって、正常な体部位又は人工的な体部位の運動を生じさせることを含む、請求項26〜42のうちいずれか一項に記載の方法。
- 前記外部デバイスと前記血管内デバイスとの間、又は前記外部デバイスと前記内部デバイスとの間のワイヤレス送受信を容易にするために、前記血管内デバイス付近の身体領域、又は前記血管内デバイスと接続された前記内部デバイス付近の身体領域の上に、外部ユニットを配置することを含む、請求項26〜43のうちいずれか一項に記載の方法。
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WO2013049887A9 (en) | 2013-05-30 |
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JP6149269B2 (ja) | 2017-06-21 |
AU2017276276A1 (en) | 2018-01-18 |
CN107374623A (zh) | 2017-11-24 |
IL267547B (en) | 2022-12-01 |
AU2019283829A1 (en) | 2020-01-23 |
EP2763745A1 (en) | 2014-08-13 |
IL231914A0 (en) | 2014-05-28 |
EP3536375A1 (en) | 2019-09-11 |
IL267547A (en) | 2019-08-29 |
US10575783B2 (en) | 2020-03-03 |
IL231914B (en) | 2019-07-31 |
US20210378595A1 (en) | 2021-12-09 |
EP2763745A4 (en) | 2015-05-27 |
CN104023787B (zh) | 2017-07-11 |
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