JP2014527083A5 - - Google Patents
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- Publication number
- JP2014527083A5 JP2014527083A5 JP2014530793A JP2014530793A JP2014527083A5 JP 2014527083 A5 JP2014527083 A5 JP 2014527083A5 JP 2014530793 A JP2014530793 A JP 2014530793A JP 2014530793 A JP2014530793 A JP 2014530793A JP 2014527083 A5 JP2014527083 A5 JP 2014527083A5
- Authority
- JP
- Japan
- Prior art keywords
- alkoxy
- cyano
- nitro
- alkanoyloxy
- alkynyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161535311P | 2011-09-15 | 2011-09-15 | |
| US61/535,311 | 2011-09-15 | ||
| US201261681519P | 2012-08-09 | 2012-08-09 | |
| US61/681,519 | 2012-08-09 | ||
| PCT/US2012/055186 WO2013040227A2 (en) | 2011-09-15 | 2012-09-13 | Therapeutic compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014527083A JP2014527083A (ja) | 2014-10-09 |
| JP2014527083A5 true JP2014527083A5 (https=) | 2015-08-20 |
Family
ID=47019147
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014530793A Pending JP2014527083A (ja) | 2011-09-15 | 2012-09-13 | 治療用化合物 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US9573906B2 (https=) |
| EP (2) | EP2755942A2 (https=) |
| JP (1) | JP2014527083A (https=) |
| AU (1) | AU2012308582B2 (https=) |
| CA (1) | CA2848540A1 (https=) |
| WO (1) | WO2013040227A2 (https=) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2755942A2 (en) | 2011-09-15 | 2014-07-23 | Arizona Board of Regents, a Body Corporate of the State of Arizona acting for and on behalf of Arizona State University | Therapeutic compounds |
| WO2015026990A2 (en) * | 2013-08-20 | 2015-02-26 | University Of Washington Through Its Center For Commercialization | Novel and specific inhibitors of cytochrome p450 26 retinoic acid hydrolase |
| US10328040B2 (en) | 2014-01-17 | 2019-06-25 | Arizona Board Of Regents On Behalf Of Arizona State University | Therapeutic methods |
| WO2015130973A1 (en) * | 2014-02-26 | 2015-09-03 | Arizona Board Of Regents On Behalf Of Arizona State University | Therapeutic compounds |
| CA2962150C (en) * | 2014-10-10 | 2023-07-04 | High Force Research Limited | Fluorescent synthetic retinoids |
| US10112917B2 (en) | 2015-03-03 | 2018-10-30 | Arizona Board Of Regents On Behalf Of Arizona State University | Therapeutic compounds |
| WO2016140978A1 (en) * | 2015-03-03 | 2016-09-09 | Arizona Board Of Regents On Behalf Of Arizona State University | Therapeutic compounds |
| US10238655B2 (en) * | 2017-01-23 | 2019-03-26 | Arizona Board Of Regents On Behalf Of Arizona State University | Dihydroindene and tetrahydronaphthalene compounds |
| US10238626B2 (en) * | 2017-01-23 | 2019-03-26 | Arizona Board Of Regents On Behalf Of Arizona State University | Therapeutic compounds |
| US10231947B2 (en) * | 2017-01-23 | 2019-03-19 | Arizona Board Of Regents On Behalf Of Arizona State University | Isochroman compounds and methods of use thereof |
| WO2020263960A1 (en) * | 2019-06-28 | 2020-12-30 | Carl Wagner | Compositions comprising a retinoid x receptor (rxr) agonist, a retinoic acid receptor (rar) agonist, or a dual rxr/rar agonist |
Family Cites Families (35)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4559157A (en) | 1983-04-21 | 1985-12-17 | Creative Products Resource Associates, Ltd. | Cosmetic applicator useful for skin moisturizing |
| LU84979A1 (fr) | 1983-08-30 | 1985-04-24 | Oreal | Composition cosmetique ou pharmaceutique sous forme aqueuse ou anhydre dont la phase grasse contient un polyether oligomere et polyethers oligomeres nouveaux |
| DE3441788A1 (de) | 1984-11-15 | 1986-05-15 | Bayer Ag, 5090 Leverkusen | Alkyl-1-cyclopropyl-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel |
| US4820508A (en) | 1987-06-23 | 1989-04-11 | Neutrogena Corporation | Skin protective composition |
| US4992478A (en) | 1988-04-04 | 1991-02-12 | Warner-Lambert Company | Antiinflammatory skin moisturizing composition and method of preparing same |
| US4938949A (en) | 1988-09-12 | 1990-07-03 | University Of New York | Treatment of damaged bone marrow and dosage units therefor |
| US7655699B1 (en) | 1992-04-22 | 2010-02-02 | Eisai Inc. | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
| US5962731A (en) | 1992-04-22 | 1999-10-05 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for retinoid X receptors, and means for modulation of processes mediated by retinoid X receptors |
| US5780676A (en) | 1992-04-22 | 1998-07-14 | Ligand Pharmaceuticals Incorporated | Compounds having selective activity for Retinoid X Receptors, and means for modulation of processes mediated by Retinoid X Receptors |
| DE10199033I2 (de) | 1992-04-22 | 2003-01-09 | Ligand Parmaceuticals Inc | Retinoid-x Rezeptor selektive Verbindungen |
| US6137002A (en) | 1993-07-22 | 2000-10-24 | Eli Lilly And Company | Glycoprotein IIb/IIIa antagonists |
| CA2233888A1 (en) * | 1995-10-06 | 1997-04-10 | Ligand Pharmaceuticals Incorporated | Dimer-selective rxr modulators and methods for their use |
| FR2746101B1 (fr) | 1996-03-14 | 1998-04-30 | Composes bicycliques-aromatiques | |
| WO1998046076A1 (en) * | 1997-04-11 | 1998-10-22 | Sidney Kimmel Cancer Center | Retinoid related molecules for the inhibition of endothelin-1 overproduction in disease |
| FR2776657B1 (fr) * | 1998-03-31 | 2000-05-26 | Cird Galderma | Composes bicycliques-aromatiques et leur utilisation en medecine humaine ou veterinaire ainsi qu'en cosmetologie |
| AU762364B2 (en) * | 1998-05-06 | 2003-06-26 | Galderma Research & Development, S.N.C. | Assay for identification of compounds that promote melanin production and retinoid-like compounds identified by said assay |
| ATE365158T1 (de) * | 1999-04-28 | 2007-07-15 | Inst Med Molecular Design Inc | Pyrimidincarbonsäurederivate |
| US6313107B1 (en) | 2000-08-29 | 2001-11-06 | Allergan Sales, Inc. | Methods of providing and using compounds having activity as inhibitors of cytochrome P450RAI |
| JP2004507531A (ja) | 2000-08-29 | 2004-03-11 | アラーガン、インコーポレイテッド | シトクロムp450rai阻害剤としての活性を有する化合物 |
| US6303785B1 (en) | 2000-08-29 | 2001-10-16 | Allergan Sales, Inc. | Compounds having activity as inhibitors of cytochrome P450RAI |
| US6291677B1 (en) | 2000-08-29 | 2001-09-18 | Allergan Sales, Inc. | Compounds having activity as inhibitors of cytochrome P450RAI |
| CN1747949A (zh) | 2002-12-20 | 2006-03-15 | 法马西亚公司 | 无环吡唑化合物 |
| AU2004263156B2 (en) * | 2003-08-07 | 2009-02-26 | Allergan, Inc. | Method for treating cachexia with retinoid ligands |
| EP1541549A1 (en) | 2003-12-12 | 2005-06-15 | Exonhit Therapeutics S.A. | Tricyclic hydroxamate and benzaminde derivatives, compositions and methods |
| US7226951B2 (en) | 2003-12-17 | 2007-06-05 | Allergan, Inc. | Compounds having selective cytochrome P450RAI-1 or selective cytochrome P450RAI-2 inhibitory activity and methods of obtaining the same |
| CA2550010A1 (en) | 2003-12-17 | 2005-06-30 | Allergan, Inc. | Methods for treating retinoid responsive disorders using selective inhibitors of cyp26a and cyp26b |
| WO2007022437A2 (en) * | 2005-08-18 | 2007-02-22 | Auspex Pharmaceuticals, Inc. | Therapeutic agents for the treatment of cancer and metabolic disorders |
| CA2662218A1 (en) * | 2006-08-29 | 2008-03-06 | Reinnervate Limited | Retinoid compounds and their use |
| CN113636966B (zh) | 2007-01-15 | 2024-01-12 | 于崇曦 | 维生素a酸类和类维生素a酸化合物的前药 |
| WO2010096264A2 (en) | 2009-02-03 | 2010-08-26 | Children's Medical Center Corporation | Methods for enhancing hematopoietic stem/progenitor cell engraftment |
| US20120115912A1 (en) | 2009-07-10 | 2012-05-10 | Landreth Gary E | Rxr agonist compounds and methods |
| CN102892755A (zh) * | 2009-12-23 | 2013-01-23 | 韦恩州立大学 | 治疗性化合物 |
| US9174917B2 (en) | 2010-02-19 | 2015-11-03 | Arizona Board Of Regents On Behalf Of Arizona State University | Bexarotene analogs |
| JP5743129B2 (ja) | 2010-04-16 | 2015-07-01 | Dic株式会社 | 重合性化合物を含有する液晶組成物及びそれを使用した液晶表示素子 |
| EP2755942A2 (en) | 2011-09-15 | 2014-07-23 | Arizona Board of Regents, a Body Corporate of the State of Arizona acting for and on behalf of Arizona State University | Therapeutic compounds |
-
2012
- 2012-09-13 EP EP12772840.0A patent/EP2755942A2/en not_active Withdrawn
- 2012-09-13 WO PCT/US2012/055186 patent/WO2013040227A2/en not_active Ceased
- 2012-09-13 JP JP2014530793A patent/JP2014527083A/ja active Pending
- 2012-09-13 AU AU2012308582A patent/AU2012308582B2/en not_active Expired - Fee Related
- 2012-09-13 EP EP15154401.2A patent/EP2910549A1/en not_active Withdrawn
- 2012-09-13 CA CA2848540A patent/CA2848540A1/en not_active Abandoned
- 2012-09-13 US US14/344,867 patent/US9573906B2/en active Active
-
2017
- 2017-01-04 US US15/398,584 patent/US10391093B2/en active Active
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