JP2014526681A - 造血毒性を評価するための手段及び方法 - Google Patents

造血毒性を評価するための手段及び方法 Download PDF

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Publication number
JP2014526681A
JP2014526681A JP2014529131A JP2014529131A JP2014526681A JP 2014526681 A JP2014526681 A JP 2014526681A JP 2014529131 A JP2014529131 A JP 2014529131A JP 2014529131 A JP2014529131 A JP 2014529131A JP 2014526681 A JP2014526681 A JP 2014526681A
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Japan
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subject
biomarker
hematopoietic toxicity
group
toxicity
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JP2014529131A
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Japanese (ja)
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JP2014526681A5 (https=
Inventor
ベー． ウォーク，ティルマン
ヴァン ラヴェンツヴァーイ，ベナード
メラート，ヴェルナー
ファビアン，エリック
シュトラウス，フォルカー
カンプ，ヘニッケ
ツェー ヴィーマー，ヤン
ルーサー，ラルフ
マンフレッド ヘロルド，ミヒャエル
プロコディーヌ，アレクサンドル
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BASF SE
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BASF SE
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Publication date
Application filed by BASF SE filed Critical BASF SE
Publication of JP2014526681A publication Critical patent/JP2014526681A/ja
Publication of JP2014526681A5 publication Critical patent/JP2014526681A5/ja
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/60—Complex ways of combining multiple protein biomarkers for diagnosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/709—Toxin induced

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2014529131A 2011-09-13 2012-09-12 造血毒性を評価するための手段及び方法 Pending JP2014526681A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201161533867P 2011-09-13 2011-09-13
EP11181156 2011-09-13
US61/533,867 2011-09-13
EP11181156.8 2011-09-13
PCT/IB2012/054731 WO2013038341A1 (en) 2011-09-13 2012-09-12 Means and methods for assessing hematopoietic toxicity

Publications (2)

Publication Number Publication Date
JP2014526681A true JP2014526681A (ja) 2014-10-06
JP2014526681A5 JP2014526681A5 (https=) 2015-11-05

Family

ID=47882692

Family Applications (1)

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JP2014529131A Pending JP2014526681A (ja) 2011-09-13 2012-09-12 造血毒性を評価するための手段及び方法

Country Status (10)

Country Link
US (1) US20150037825A1 (https=)
EP (1) EP2756301A4 (https=)
JP (1) JP2014526681A (https=)
KR (1) KR20140059805A (https=)
CN (2) CN106053832A (https=)
AU (1) AU2012310147A1 (https=)
BR (1) BR112014005472A2 (https=)
CA (1) CA2845621A1 (https=)
IL (1) IL231007A0 (https=)
WO (1) WO2013038341A1 (https=)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114594192A (zh) * 2022-03-07 2022-06-07 山东大学 一种泊沙康唑起始物料中氯苯胺和氯硝基苯胺同分异构体的检测方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003245076A (ja) * 2001-01-30 2003-09-02 Takeda Chem Ind Ltd 新規タンパク質およびそのｄｎａ
US20040121305A1 (en) * 2002-12-18 2004-06-24 Wiegand Roger Charles Generation of efficacy, toxicity and disease signatures and methods of use thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7112409B2 (en) * 1999-01-29 2006-09-26 Center For Molecular Medicine And Immunology Method of determining cytokine dosage for myelosuppressive state
AU2003258319B2 (en) * 2002-08-21 2009-09-17 Hemogenix, Inc. High-throughput assay of hematopoietic stem and progenitor cell proliferation
US8034613B2 (en) * 2005-06-01 2011-10-11 Wisconsin Alumni Research Foundation Multipotent lymphohematopoietic progenitor cells
CN101529249A (zh) * 2006-08-30 2009-09-09 梅坦诺米克斯有限公司 用于诊断溶血性贫血的工具和方法
US7689187B2 (en) * 2007-03-01 2010-03-30 Motorola, Inc. Dual input low noise amplifier for multi-band operation
US8062222B2 (en) * 2007-06-13 2011-11-22 Litron Laboratories, Ltd. Method for measuring in vivo hematotoxicity with an emphasis on radiation exposure assessment
WO2009153136A2 (en) * 2008-05-28 2009-12-23 Basf Se Means and methods for assessing liver toxicity

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003245076A (ja) * 2001-01-30 2003-09-02 Takeda Chem Ind Ltd 新規タンパク質およびそのｄｎａ
US20040121305A1 (en) * 2002-12-18 2004-06-24 Wiegand Roger Charles Generation of efficacy, toxicity and disease signatures and methods of use thereof

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JPN6016028296; Ｗｉｌｂｅｒｔ　Ｈ．　Ｍ．　Ｈｅｉｊｉｎｅ　ｅｔ　ａｌ．: Ｍｕｔａｔｉｏｎ　Ｒｅｓｅａｒｃｈ ５７５, 20050506, ８５-１０１ *
JPN6016028298; Ｓａｔｏｋｏ　Ｎ．　ｅｔ　ａｌ．: Ｊｏｕｒｎａｌ　ｏｆ　Ｐａｒｅｎｔｅｒａｌ　ａｎｄ　Ｅｎｔｅｒａｌ　Ｎｕｔｒｉｔｉｏｎ Ｖｏｌ．　３４，　Ｎｏ．　５, 201009, ５３０-５３７ *
JPN6016030216; Ｐｅｄｅｒｓｅｎ　Ｃ　ｅｔ　ａｌ: ＡＩＤＳ Ｖｏｌ．３，　Ｎｏ．１１, 198911, ａｂｓｔｒａｃｔ *

Also Published As

Publication number Publication date
US20150037825A1 (en) 2015-02-05
IL231007A0 (en) 2014-03-31
CN103827667B (zh) 2016-07-13
EP2756301A4 (en) 2015-08-12
CN103827667A (zh) 2014-05-28
WO2013038341A1 (en) 2013-03-21
CA2845621A1 (en) 2013-03-21
CN106053832A (zh) 2016-10-26
KR20140059805A (ko) 2014-05-16
BR112014005472A2 (pt) 2017-03-28
EP2756301A1 (en) 2014-07-23
AU2012310147A1 (en) 2014-03-13

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