JP2014523525A5 - - Google Patents
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- Publication number
- JP2014523525A5 JP2014523525A5 JP2014514556A JP2014514556A JP2014523525A5 JP 2014523525 A5 JP2014523525 A5 JP 2014523525A5 JP 2014514556 A JP2014514556 A JP 2014514556A JP 2014514556 A JP2014514556 A JP 2014514556A JP 2014523525 A5 JP2014523525 A5 JP 2014523525A5
- Authority
- JP
- Japan
- Prior art keywords
- subject
- nthi
- respiratory tract
- upper respiratory
- biomarker
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 210000002345 respiratory system Anatomy 0.000 claims description 100
- 108090000623 proteins and genes Proteins 0.000 claims description 59
- 102000004169 proteins and genes Human genes 0.000 claims description 59
- 239000000090 biomarker Substances 0.000 claims description 52
- 238000000034 method Methods 0.000 claims description 48
- 241000894006 Bacteria Species 0.000 claims description 44
- 238000003018 immunoassay Methods 0.000 claims description 39
- 208000015181 infectious disease Diseases 0.000 claims description 38
- 208000035143 Bacterial infection Diseases 0.000 claims description 29
- 208000022362 bacterial infectious disease Diseases 0.000 claims description 29
- 230000001225 therapeutic effect Effects 0.000 claims description 28
- 101710167677 Outer membrane protein P2 Proteins 0.000 claims description 17
- 101710167675 Outer membrane protein P5 Proteins 0.000 claims description 17
- 150000001875 compounds Chemical class 0.000 claims description 17
- 230000028327 secretion Effects 0.000 claims description 17
- 239000000758 substrate Substances 0.000 claims description 11
- 239000003814 drug Substances 0.000 claims description 6
- 206010022000 influenza Diseases 0.000 claims description 6
- 241000606768 Haemophilus influenzae Species 0.000 claims description 5
- 206010009137 Chronic sinusitis Diseases 0.000 claims description 3
- 208000027157 chronic rhinosinusitis Diseases 0.000 claims description 3
- 238000003745 diagnosis Methods 0.000 claims description 3
- 238000000691 measurement method Methods 0.000 claims description 2
- 244000052769 pathogen Species 0.000 description 18
- 244000052616 bacterial pathogen Species 0.000 description 17
- 230000001717 pathogenic effect Effects 0.000 description 15
- 241000589516 Pseudomonas Species 0.000 description 6
- 241000588655 Moraxella catarrhalis Species 0.000 description 3
- 241000191967 Staphylococcus aureus Species 0.000 description 3
- 241000122973 Stenotrophomonas maltophilia Species 0.000 description 3
- 241000193998 Streptococcus pneumoniae Species 0.000 description 3
- 229940031000 streptococcus pneumoniae Drugs 0.000 description 3
- 229940047650 haemophilus influenzae Drugs 0.000 description 2
- 208000035473 Communicable disease Diseases 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161493829P | 2011-06-06 | 2011-06-06 | |
| US61/493,829 | 2011-06-06 | ||
| PCT/US2012/040910 WO2012170422A1 (en) | 2011-06-06 | 2012-06-05 | Proteomics based diagnostic detection method for chronic sinusitis |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016160374A Division JP2016194532A (ja) | 2011-06-06 | 2016-08-18 | プロテオミクスに基づく、慢性副鼻腔炎の診断用検出方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014523525A JP2014523525A (ja) | 2014-09-11 |
| JP2014523525A5 true JP2014523525A5 (enExample) | 2015-07-23 |
| JP6050337B2 JP6050337B2 (ja) | 2016-12-21 |
Family
ID=46208851
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014514556A Active JP6050337B2 (ja) | 2011-06-06 | 2012-06-05 | プロテオミクスに基づく、慢性副鼻腔炎の診断用検出方法 |
| JP2016160374A Pending JP2016194532A (ja) | 2011-06-06 | 2016-08-18 | プロテオミクスに基づく、慢性副鼻腔炎の診断用検出方法 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016160374A Pending JP2016194532A (ja) | 2011-06-06 | 2016-08-18 | プロテオミクスに基づく、慢性副鼻腔炎の診断用検出方法 |
Country Status (9)
| Country | Link |
|---|---|
| US (4) | US9568472B2 (enExample) |
| EP (1) | EP2718722B1 (enExample) |
| JP (2) | JP6050337B2 (enExample) |
| AU (1) | AU2012268380C1 (enExample) |
| CA (1) | CA2838488C (enExample) |
| DK (1) | DK2718722T3 (enExample) |
| ES (1) | ES2649370T3 (enExample) |
| PL (1) | PL2718722T3 (enExample) |
| WO (1) | WO2012170422A1 (enExample) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103687613A (zh) * | 2011-05-11 | 2014-03-26 | 里斯贝克保健瑞典股份公司 | 蛋白f-具有层粘连蛋白和玻连蛋白结合性能的新的流感嗜血杆菌粘附素 |
| EP2718722B1 (en) * | 2011-06-06 | 2017-10-18 | Nationwide Children's Hospital, Inc. | Proteomics based diagnostic detection method for chronic sinusitis |
| JP2015508755A (ja) * | 2012-02-01 | 2015-03-23 | オクラホマ メディカル リサーチ ファウンデーションＯｋｌａｈｏｍａ Ｍｅｄｉｃａｌ Ｒｅｓｅａｒｃｈｆｏｕｎｄａｔｉｏｎ | ヒト肺炎連鎖球菌抗体およびその使用 |
| CN105979779A (zh) * | 2013-08-16 | 2016-09-28 | 俄亥俄州国家创新基金会 | 调整dna甲基化的组合物和方法 |
| US9606118B2 (en) * | 2015-03-30 | 2017-03-28 | Entvantage Diagnostics, Inc. | Devices and assays for diagnosis of sinusitis |
| US10921320B2 (en) | 2015-03-30 | 2021-02-16 | Entvantage Diagnostics, Inc. | Devices and methods for diagnosis of sinusitis |
| US11650213B2 (en) | 2015-03-30 | 2023-05-16 | Entvantage Diagnostics, Inc. | Devices and assays for diagnosis of viral and bacterial infections |
| CA3057853A1 (en) | 2017-03-28 | 2018-10-04 | Entvantage Diagnostics, Inc. | Devices and methods for diagnosis of sinusitis |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0664065B2 (ja) * | 1985-12-23 | 1994-08-22 | 日水製薬株式会社 | 菌体外膜保有菌の免疫学的測定法 |
| US5763262A (en) | 1986-09-18 | 1998-06-09 | Quidel Corporation | Immunodiagnostic device |
| KR910014706A (ko) | 1990-01-10 | 1991-08-31 | 원본미기재 | 세척이 필요없는 개량된 이뮤노어세이(immunoassay)장치 |
| US20020164354A1 (en) | 1998-09-30 | 2002-11-07 | Barenkamp Stephen J. | High molecular weight surface proteins of non-typeable haemphilus |
| US5415994A (en) | 1993-08-02 | 1995-05-16 | Quidel Corporation | Lateral flow medical diagnostic assay device with sample extraction means |
| ATE527059T1 (de) * | 2004-03-18 | 2011-10-15 | Nissui Pharm Co Ltd | Methode zur herstellung einer analytischen vorrichtung und kit |
| WO2010079739A1 (ja) * | 2009-01-07 | 2010-07-15 | 大塚製薬株式会社 | 全インフルエンザ菌の測定方法 |
| US8617574B2 (en) * | 2009-02-13 | 2013-12-31 | Valneva Austria Gmbh | Nontypable Haemophilus influenzae antigens |
| US20120276145A1 (en) * | 2011-03-28 | 2012-11-01 | House Research Institute | Extracellular matrix proteins from haemophilus influenzae biofilms: targets for therapeutic or diagnostic use |
| EP2718722B1 (en) * | 2011-06-06 | 2017-10-18 | Nationwide Children's Hospital, Inc. | Proteomics based diagnostic detection method for chronic sinusitis |
-
2012
- 2012-06-05 EP EP12726000.8A patent/EP2718722B1/en active Active
- 2012-06-05 WO PCT/US2012/040910 patent/WO2012170422A1/en not_active Ceased
- 2012-06-05 DK DK12726000.8T patent/DK2718722T3/en active
- 2012-06-05 ES ES12726000.8T patent/ES2649370T3/es active Active
- 2012-06-05 CA CA2838488A patent/CA2838488C/en active Active
- 2012-06-05 JP JP2014514556A patent/JP6050337B2/ja active Active
- 2012-06-05 US US14/124,470 patent/US9568472B2/en active Active
- 2012-06-05 PL PL12726000T patent/PL2718722T3/pl unknown
- 2012-06-05 AU AU2012268380A patent/AU2012268380C1/en active Active
-
2016
- 2016-08-18 JP JP2016160374A patent/JP2016194532A/ja active Pending
-
2017
- 2017-01-12 US US15/404,681 patent/US10048261B2/en active Active
-
2018
- 2018-07-18 US US16/039,031 patent/US10345300B2/en active Active
-
2019
- 2019-06-24 US US16/450,476 patent/US10725040B2/en active Active
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