JP2014523330A - 留置型経皮的デバイスの感染を予防するための薬物溶出メッシュ - Google Patents

留置型経皮的デバイスの感染を予防するための薬物溶出メッシュ Download PDF

Info

Publication number
JP2014523330A
JP2014523330A JP2014521814A JP2014521814A JP2014523330A JP 2014523330 A JP2014523330 A JP 2014523330A JP 2014521814 A JP2014521814 A JP 2014521814A JP 2014521814 A JP2014521814 A JP 2014521814A JP 2014523330 A JP2014523330 A JP 2014523330A
Authority
JP
Japan
Prior art keywords
hours
poly
active agent
rifampin
tyrosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2014521814A
Other languages
English (en)
Japanese (ja)
Other versions
JP2014523330A5 (enExample
Inventor
ラーナー，ダニエル・ジェレミー
マクジェイムズ，ウィリアム
マンスフィールド，ランディ
ホワイト，ロバート・エス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medtronic PLC
Original Assignee
TYRX Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by TYRX Inc filed Critical TYRX Inc
Publication of JP2014523330A publication Critical patent/JP2014523330A/ja
Publication of JP2014523330A5 publication Critical patent/JP2014523330A5/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/04—Macromolecular materials
    • A61L31/06—Macromolecular materials obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/146—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602—Type of release, e.g. controlled, sustained, slow
    • A61L2300/604—Biodegradation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/606—Coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2420/00—Materials or methods for coatings medical devices
    • A61L2420/06—Coatings containing a mixture of two or more compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Vascular Medicine (AREA)
  • Epidemiology (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polymers & Plastics (AREA)
JP2014521814A 2011-07-20 2012-07-20 留置型経皮的デバイスの感染を予防するための薬物溶出メッシュ Pending JP2014523330A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161509843P 2011-07-20 2011-07-20
US61/509,843 2011-07-20
PCT/US2012/047542 WO2013013123A1 (en) 2011-07-20 2012-07-20 Drug eluting mesh to prevent infection of indwelling transdermal devices

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2016137619A Division JP2016221297A (ja) 2011-07-20 2016-07-12 留置型経皮的デバイスの感染を予防するための薬物溶出メッシュ

Publications (2)

Publication Number Publication Date
JP2014523330A true JP2014523330A (ja) 2014-09-11
JP2014523330A5 JP2014523330A5 (enExample) 2015-08-20

Family

ID=46650881

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2014521814A Pending JP2014523330A (ja) 2011-07-20 2012-07-20 留置型経皮的デバイスの感染を予防するための薬物溶出メッシュ
JP2016137619A Pending JP2016221297A (ja) 2011-07-20 2016-07-12 留置型経皮的デバイスの感染を予防するための薬物溶出メッシュ

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2016137619A Pending JP2016221297A (ja) 2011-07-20 2016-07-12 留置型経皮的デバイスの感染を予防するための薬物溶出メッシュ

Country Status (6)

Country Link
US (1) US9381281B2 (enExample)
EP (1) EP2734248B1 (enExample)
JP (2) JP2014523330A (enExample)
AU (1) AU2012283875B2 (enExample)
CA (1) CA2842107C (enExample)
WO (1) WO2013013123A1 (enExample)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014137454A1 (en) * 2013-03-07 2014-09-12 Tyrx, Inc. Methods and compositions to inhibit the assemblage of microbial cells irreversibly associated with surfaces of medical devices
GB201505527D0 (en) * 2015-03-31 2015-05-13 Jmedtech Pte Ltd Composition
CN107743404A (zh) 2015-06-18 2018-02-27 心脏起搏器股份公司 用于可植入医疗装置的包含生物可吸收聚合物和抗微生物剂的聚合物覆盖物及其生产方法
WO2017011321A1 (en) 2015-07-11 2017-01-19 Cardiac Pacemakers, Inc. Polymer coating with antimicrobial materials and methods for producing
US9999899B2 (en) 2016-11-01 2018-06-19 International Business Machines Corporation Controlled exposure of in-vivo sensors
WO2019036759A1 (en) * 2017-08-24 2019-02-28 Boulos & Cooper Pharmaceuticals Pty Ltd ANTIMICROBIAL COATING
CN111432807A (zh) 2017-10-06 2020-07-17 铸造疗法股份有限公司 用于控制释放治疗剂的可植入贮库
US9919080B1 (en) * 2017-10-27 2018-03-20 Tyrx, Inc. Kits for local delivery of water soluble agents and methods of use
WO2019136490A1 (en) 2018-01-08 2019-07-11 Foundry Therapeutics, Inc. Devices, systems, and methods for treating intraluminal cancer via controlled delivery of therapeutic agents
EP3793536A1 (en) 2018-05-12 2021-03-24 Foundry Therapeutics, Inc. Implantable polymer depots for the controlled release of therapeutic agents
EP3843710A1 (en) 2018-08-28 2021-07-07 Foundry Therapeutics, Inc. Polymer implants

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010508915A (ja) * 2006-11-06 2010-03-25 タイレックス・ファーマ・インコーポレイテッド 埋込型医療機器のためのメッシュパウチ

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4980449A (en) 1988-07-14 1990-12-25 Rutgers, The State University Polyiminocarbonate synthesis
US5099060A (en) 1990-06-12 1992-03-24 Rutgers, The State University Of New Jersey Synthesis of amino acid-derived bioerodible polymers
US5216115A (en) 1990-06-12 1993-06-01 Rutgers, The State University Of New Jersey Polyarylate containing derivatives of the natural amino acid L-tyrosine
USRE37160E1 (en) 1990-06-12 2001-05-01 Rutgers, The State University Synthesis of tyrosine derived diphenol monomers
US5587507A (en) 1995-03-31 1996-12-24 Rutgers, The State University Synthesis of tyrosine derived diphenol monomers
US5658995A (en) 1995-11-27 1997-08-19 Rutgers, The State University Copolymers of tyrosine-based polycarbonate and poly(alkylene oxide)
US6319492B1 (en) 1996-11-27 2001-11-20 Rutgers, The State University Copolymers of tyrosine-based polyarylates and poly(alkylene oxides)
US6048521A (en) 1997-11-07 2000-04-11 Rutgers, The State University Copolymers of tyrosine-based polyarlates and poly(alkylene oxides)
US6120491A (en) 1997-11-07 2000-09-19 The State University Rutgers Biodegradable, anionic polymers derived from the amino acid L-tyrosine
US6475477B1 (en) 1997-11-07 2002-11-05 Rutgers, The State University Radio-opaque polymer biomaterials
US6602497B1 (en) 1997-11-07 2003-08-05 Rutgers, The State University Strictly alternating poly(alkylene oxide ether) copolymers
WO1999052962A1 (en) 1998-04-13 1999-10-21 Rutgers, The State University The construction of copolymer libraries
US7521061B2 (en) 1999-12-31 2009-04-21 Rutgers, The State University Of New Jersey Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix
AU784226B2 (en) 1999-12-31 2006-02-23 Rutgers, The State University Pharmaceutical formulation for regulating the timed release of biologically active compounds based on a polymer matrix
CA2395892C (en) 1999-12-31 2014-06-03 Rutgers, The State University Pharmaceutical formulation composed of a polymer blend and an active compound for time-controlled release
US7271234B2 (en) 2002-04-24 2007-09-18 Rutgers, The State University Of New Jersey Polyarylates for drug delivery and tissue engineering
MX2008010126A (es) 2006-02-08 2010-02-22 Tyrx Pharma Inc Protesis de malla temporalmente rigidizadas.
US8591531B2 (en) * 2006-02-08 2013-11-26 Tyrx, Inc. Mesh pouches for implantable medical devices
US9486560B2 (en) * 2006-02-08 2016-11-08 Tyrx, Inc. Mesh pouches for implantable medical devices
US8315700B2 (en) 2006-02-08 2012-11-20 Tyrx, Inc. Preventing biofilm formation on implantable medical devices
EP2079491B1 (en) * 2006-10-17 2013-02-27 Reva Medical, Inc. N-substituted monomers and polymers
US20080146869A1 (en) * 2006-10-30 2008-06-19 Hector Chow Adjustable Gastric Band Having Anti-Microbial Coatings
JP5847706B2 (ja) * 2009-06-01 2016-01-27 タイレックス・インコーポレイテッドＴｙｒｘ Ｉｎｃ． 胸骨創感染症を予防するための組成物および方法
US9080015B2 (en) * 2009-07-31 2015-07-14 Rutgers, The State University Of New Jersey Biocompatible polymers for medical devices
CA2816343C (en) * 2010-11-12 2017-01-17 Tyrx, Inc. Anchorage devices comprising an active pharmaceutical ingredient

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2010508915A (ja) * 2006-11-06 2010-03-25 タイレックス・ファーマ・インコーポレイテッド 埋込型医療機器のためのメッシュパウチ

Also Published As

Publication number Publication date
US9381281B2 (en) 2016-07-05
EP2734248B1 (en) 2018-10-17
CA2842107A1 (en) 2013-01-24
US20140220098A1 (en) 2014-08-07
JP2016221297A (ja) 2016-12-28
AU2012283875A1 (en) 2014-02-13
EP2734248A1 (en) 2014-05-28
WO2013013123A1 (en) 2013-01-24
AU2012283875B2 (en) 2016-05-12
CA2842107C (en) 2018-01-16

Similar Documents

Publication Publication Date Title
US9381281B2 (en) Drug eluting mesh to prevent infection of indwelling transdermal devices
EP2637713B1 (en) Anchorage devices comprising an active pharmaceutical ingredient
US10765500B2 (en) Temporarily stiffened mesh prostheses
JP5398535B2 (ja) 埋込型医療機器のための吸収性パウチ
AU2007351374B2 (en) Mesh pouches for implantable medical devices
AU2013200515C1 (en) Mesh pouches for implantable medical devices
AU2015264956B2 (en) Anchorage devices comprising an active pharmaceutical ingredient
WO2023037187A1 (en) Surgical system and methods of use
CA2637578C (en) Temporarily stiffened mesh prostheses
AU2013200627A1 (en) Resorbable pouches for implantable medical devices

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20150701

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20150701

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20160412

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20161124