JP2014521636A - ペプチドおよびポリペプチド分子の制御放出のためのマトリクス組成物 - Google Patents

ペプチドおよびポリペプチド分子の制御放出のためのマトリクス組成物 Download PDF

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JP2014521636A
JP2014521636A JP2014522216A JP2014522216A JP2014521636A JP 2014521636 A JP2014521636 A JP 2014521636A JP 2014522216 A JP2014522216 A JP 2014522216A JP 2014522216 A JP2014522216 A JP 2014522216A JP 2014521636 A JP2014521636 A JP 2014521636A
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matrix composition
another embodiment
lipid
fatty acid
matrix
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JP2014521636A5 (enExample
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エマヌエル,ノアム
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ポリピッド リミテッド
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
    • A61K9/1273Polymersomes; Liposomes with polymerisable or polymerised bilayer-forming substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18Growth factors; Growth regulators
    • A61K38/1825Fibroblast growth factor [FGF]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)
JP2014522216A 2011-07-27 2012-07-26 ペプチドおよびポリペプチド分子の制御放出のためのマトリクス組成物 Pending JP2014521636A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161512025P 2011-07-27 2011-07-27
US61/512,025 2011-07-27
PCT/IL2012/050278 WO2013014677A1 (en) 2011-07-27 2012-07-26 Matrix compositions for controlled release of peptide and polypeptide molecules

Publications (2)

Publication Number Publication Date
JP2014521636A true JP2014521636A (ja) 2014-08-28
JP2014521636A5 JP2014521636A5 (enExample) 2015-09-10

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JP2014522216A Pending JP2014521636A (ja) 2011-07-27 2012-07-26 ペプチドおよびポリペプチド分子の制御放出のためのマトリクス組成物

Country Status (7)

Country Link
US (1) US20140271861A1 (enExample)
EP (1) EP2736492A4 (enExample)
JP (1) JP2014521636A (enExample)
CN (1) CN103717206A (enExample)
AU (1) AU2012288422B2 (enExample)
CA (1) CA2838481A1 (enExample)
WO (1) WO2013014677A1 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160340659A1 (en) 2014-01-30 2016-11-24 Yissum Research And Development Company Of The Hebrew University Of Jerusalem Ltd. Actin binding peptides and compositions comprising same for inhibiting angiogenesis and treating medical conditions associated with same
US10682442B2 (en) 2014-04-04 2020-06-16 University Of Kentucky Research Foundation Small molecule drug release from in situ forming degradable scaffolds incorporating hydrogels and bioceramic microparticles
US11406742B2 (en) 2014-07-18 2022-08-09 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
US9492594B2 (en) * 2014-07-18 2016-11-15 M.A. Med Alliance SA Coating for intraluminal expandable catheter providing contact transfer of drug micro-reservoirs
US10182993B2 (en) * 2015-04-06 2019-01-22 Patheon Softgels Inc. Compositions for colonic delivery of drugs
US11464860B2 (en) 2017-10-27 2022-10-11 Massachusetts Institute Of Technology Poly (beta-amino esters) and uses thereof
CA3117781A1 (en) * 2018-10-26 2020-04-30 Massachusetts Institute Of Technology Polymer-lipids and compositions
WO2022192176A1 (en) 2021-03-09 2022-09-15 Massachusetts Institute Of Technology Branched poly(-amino esters) for the delivery of nucleic acids

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09510477A (ja) * 1994-06-18 1997-10-21 ユニバーシティ オブ ノッティンガム 薬剤移送用ポリマーミクロ粒子
JP2007524628A (ja) * 2003-06-26 2007-08-30 シヴィダ・インコーポレイテッド In−Situゲル化薬物輸送システム
WO2010007623A1 (en) * 2008-07-14 2010-01-21 Polypid Ltd. Sustained-release drug carrier composition
US20100196482A1 (en) * 2007-04-04 2010-08-05 Massachusetts Institute Of Technology Polymer-encapsulated reverse micelles
WO2011007353A1 (en) * 2009-07-14 2011-01-20 Polypid Ltd. Sustained-release drug carrier composition

Family Cites Families (10)

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US6423345B2 (en) * 1998-04-30 2002-07-23 Acusphere, Inc. Matrices formed of polymer and hydrophobic compounds for use in drug delivery
WO2002028408A2 (en) * 2000-10-02 2002-04-11 Arizeke Pharmaceuticals, Inc. Compositions and methods for the transport of biologically active agents across cellular barriers
US20060140904A1 (en) * 2003-02-12 2006-06-29 Tadeusz Wellisz Random alkylene oxide copolymers for medical and surgical utilities
US20040247624A1 (en) * 2003-06-05 2004-12-09 Unger Evan Charles Methods of making pharmaceutical formulations for the delivery of drugs having low aqueous solubility
US8277831B2 (en) * 2004-02-17 2012-10-02 Advanced Technologies And Regenerative Medicine, Llc. Drug-enhanced adhesion prevention
CA2578709C (en) * 2004-06-17 2010-06-15 Virun, Inc. Compositions comprising a mucoadhesive protein and an active principle for mucosal delivery of said agents
WO2008105773A2 (en) * 2006-03-31 2008-09-04 Massachusetts Institute Of Technology System for targeted delivery of therapeutic agents
US8703167B2 (en) * 2006-06-05 2014-04-22 Advanced Cardiovascular Systems, Inc. Coatings for implantable medical devices for controlled release of a hydrophilic drug and a hydrophobic drug
WO2010083337A2 (en) * 2009-01-15 2010-07-22 The Regents Of The University Of Califorinia Composite nanostructures and methods for making and using them
CN101555212B (zh) * 2009-05-22 2012-06-20 戴立忠 能输送生物活性物质的合成小分子化合物及其应用

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH09510477A (ja) * 1994-06-18 1997-10-21 ユニバーシティ オブ ノッティンガム 薬剤移送用ポリマーミクロ粒子
JP2007524628A (ja) * 2003-06-26 2007-08-30 シヴィダ・インコーポレイテッド In−Situゲル化薬物輸送システム
US20100196482A1 (en) * 2007-04-04 2010-08-05 Massachusetts Institute Of Technology Polymer-encapsulated reverse micelles
WO2010007623A1 (en) * 2008-07-14 2010-01-21 Polypid Ltd. Sustained-release drug carrier composition
WO2011007353A1 (en) * 2009-07-14 2011-01-20 Polypid Ltd. Sustained-release drug carrier composition

Also Published As

Publication number Publication date
CN103717206A (zh) 2014-04-09
CA2838481A1 (en) 2013-01-31
EP2736492A4 (en) 2015-06-17
EP2736492A1 (en) 2014-06-04
US20140271861A1 (en) 2014-09-18
WO2013014677A8 (en) 2013-09-06
WO2013014677A1 (en) 2013-01-31
AU2012288422B2 (en) 2016-08-11

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