JP2014521372A5

JP2014521372A5 -

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Publication number: JP2014521372A5
Authority: JP; Japan
Prior art keywords: dose; syringe; delivery guide; loading; dose delivery
Prior art date: 2012-04-25
Legal status : Granted

Application number

JP2014508521A

Other languages

English (en)

Japanese (ja)

Other versions

JP2014521372A (ja

JP6215193B2 (ja

Filing date

2012-04-25

Publication date

2016-07-21

2012-04-25 Application filed filed Critical

2012-04-25 Priority claimed from PCT/US2012/035028 external-priority patent/WO2012149040A2/en

2014-08-28 Publication of JP2014521372A publication Critical patent/JP2014521372A/ja

2016-07-21 Publication of JP2014521372A5 publication Critical patent/JP2014521372A5/ja

2017-10-18 Application granted granted Critical

2017-10-18 Publication of JP6215193B2 publication Critical patent/JP6215193B2/ja

Status Active legal-status Critical Current

2032-04-25 Anticipated expiration legal-status Critical

Links

NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims description 8
102000004877 Insulin Human genes 0.000 claims description 4
108090001061 Insulin Proteins 0.000 claims description 4
229940125396 insulin Drugs 0.000 claims description 4
239000011521 glass Substances 0.000 claims description 3
230000009977 dual effect Effects 0.000 claims 8
239000013583 drug formulation Substances 0.000 claims 2
238000000034 method Methods 0.000 claims 2
108010081667 aflibercept Proteins 0.000 claims 1
229960000397 bevacizumab Drugs 0.000 claims 1
UREBDLICKHMUKA-CXSFZGCWSA-N dexamethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(F)[C@@H]1[C@@H]1C[C@@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O UREBDLICKHMUKA-CXSFZGCWSA-N 0.000 claims 1
239000012530 fluid Substances 0.000 claims 1
238000007373 indentation Methods 0.000 claims 1
229960003876 ranibizumab Drugs 0.000 claims 1
125000006850 spacer group Chemical group 0.000 description 2
238000004128 high performance liquid chromatography Methods 0.000 description 1
229960001005 tuberculin Drugs 0.000 description 1

JP2014508521A 2011-04-25 2012-04-25 注射器の用量ガイド Active JP6215193B2 (ja)