JP2014521088A - 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 - Google Patents
腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 Download PDFInfo
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Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54306—Solid-phase reaction mechanisms
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/475—Assays involving growth factors
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/575—Hormones
- G01N2333/59—Follicle-stimulating hormone [FSH]; Chorionic gonadotropins, e.g. HCG; Luteinising hormone [LH]; Thyroid-stimulating hormone [TSH]
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/81—Protease inhibitors
- G01N2333/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/34—Genitourinary disorders
- G01N2800/347—Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/56—Staging of a disease; Further complications associated with the disease
Landscapes
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
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| US201161506038P | 2011-07-09 | 2011-07-09 | |
| US61/506,038 | 2011-07-09 | ||
| PCT/US2012/045583 WO2013009573A1 (en) | 2011-07-09 | 2012-07-05 | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Publications (2)
| Publication Number | Publication Date |
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| JP2014521088A true JP2014521088A (ja) | 2014-08-25 |
| JP2014521088A5 JP2014521088A5 (https=) | 2015-08-20 |
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| JP2014520221A Pending JP2014521088A (ja) | 2011-07-09 | 2012-07-05 | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
Country Status (9)
| Country | Link |
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| US (2) | US20140171522A1 (https=) |
| EP (1) | EP2729803A4 (https=) |
| JP (1) | JP2014521088A (https=) |
| CN (1) | CN103858008B (https=) |
| AU (1) | AU2012282918A1 (https=) |
| CA (1) | CA2841880A1 (https=) |
| EA (1) | EA201490105A1 (https=) |
| MX (1) | MX2014000283A (https=) |
| WO (1) | WO2013009573A1 (https=) |
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| WO2014120569A1 (en) * | 2013-01-25 | 2014-08-07 | Beth Israel Deaconess Medical Center, Inc. | Methods and compositions for human epididymis protein-4 (he4) |
| WO2015081102A1 (en) | 2013-11-27 | 2015-06-04 | Gnubio, Inc. | Microfluidic droplet packing |
| CN104045453B (zh) * | 2014-06-11 | 2016-08-24 | 句容市鑫诚果业家庭农场 | 一种石榴专用有机肥料及其制备方法 |
| CN106536709A (zh) | 2014-06-16 | 2017-03-22 | 基纽拜奥股份有限公司 | 尺寸交替的注入到液滴中以促进分选 |
| CN104062294A (zh) * | 2014-07-11 | 2014-09-24 | 青岛千士医疗科技有限公司 | 一种支气管/肺上皮细胞线粒体损伤的检测方法 |
| CN104166003B (zh) * | 2014-08-06 | 2016-06-08 | 中国人民解放军第二军医大学 | 人附睾蛋白4在制备系统性红斑狼疮性肾病诊断试剂或试剂盒中的应用 |
| WO2016130802A1 (en) * | 2015-02-11 | 2016-08-18 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| TW201827070A (zh) * | 2016-12-19 | 2018-08-01 | 康鶴生醫科技股份有限公司 | 合成多肽、含該多肽的組合物、由其產生的抗體及其用途 |
| CN121186383B (zh) * | 2025-11-24 | 2026-03-13 | 华中科技大学 | 慢性肾病的蛋白质标志物的筛选及应用 |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080254485A1 (en) * | 2006-11-14 | 2008-10-16 | Biosite Incorporated | Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome |
| WO2010025424A1 (en) * | 2008-08-28 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011075744A1 (en) * | 2009-12-20 | 2011-06-23 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001016354A1 (en) * | 1999-09-02 | 2001-03-08 | Gene Logic, Inc. | Modulation of he4 in inflammatory and renal diseases |
| CN1791797A (zh) * | 2003-03-27 | 2006-06-21 | 儿童医院医疗中心 | 用于检测肾小管细胞损伤的早发的方法和试剂盒 |
| US7588892B2 (en) * | 2004-07-19 | 2009-09-15 | Entelos, Inc. | Reagent sets and gene signatures for renal tubule injury |
| US20070087387A1 (en) * | 2005-04-21 | 2007-04-19 | Prasad Devarajan | Method for the Early Detection of Renal Disease Using Proteomics |
| CN101802014A (zh) * | 2007-03-09 | 2010-08-11 | 三路影像公司 | He4单克隆抗体和它们的使用方法 |
| EP2479569A3 (en) * | 2007-03-26 | 2012-09-26 | Novartis AG | Predictive renal safety biomarkers and biomarker signatures to monitor kidney function |
| KR20100122495A (ko) * | 2008-02-29 | 2010-11-22 | 고쿠리츠 다이가쿠 호우징 나고야 다이가쿠 | 급성 신장 장해 및 예후 추정용 바이오마커 및 그 용도 |
| WO2009126380A2 (en) * | 2008-03-05 | 2009-10-15 | Singulex, Inc. | Methods and compositions for highly sensitive detection of molecules |
| CA2726563A1 (en) * | 2008-06-04 | 2009-12-10 | Proteosys Ag | Protein biomarkers for in vitro testing of developmental toxicity and embryotoxicity of chemical substances |
| AU2009316387B2 (en) * | 2008-11-22 | 2015-01-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011109830A2 (en) * | 2010-03-05 | 2011-09-09 | Case Western Reserve University | Protein biomarkers and therapeutic targets for renal disorders |
| WO2012074888A2 (en) * | 2010-11-29 | 2012-06-07 | Alere San Diego, Inc. | Methods and compositions for diagnosis and risk prediction in heart failure |
| WO2013006629A1 (en) * | 2011-07-06 | 2013-01-10 | Alere San Diego Inc. | Methods and compositions for assigning likelihood of acute kidney injury progression |
-
2012
- 2012-07-05 US US14/131,678 patent/US20140171522A1/en not_active Abandoned
- 2012-07-05 MX MX2014000283A patent/MX2014000283A/es not_active Application Discontinuation
- 2012-07-05 AU AU2012282918A patent/AU2012282918A1/en not_active Abandoned
- 2012-07-05 WO PCT/US2012/045583 patent/WO2013009573A1/en not_active Ceased
- 2012-07-05 EP EP12810709.1A patent/EP2729803A4/en not_active Withdrawn
- 2012-07-05 CA CA2841880A patent/CA2841880A1/en not_active Abandoned
- 2012-07-05 JP JP2014520221A patent/JP2014521088A/ja active Pending
- 2012-07-05 EA EA201490105A patent/EA201490105A1/ru unknown
- 2012-07-05 CN CN201280039959.5A patent/CN103858008B/zh not_active Expired - Fee Related
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2015
- 2015-12-09 US US14/964,410 patent/US20160097779A1/en not_active Abandoned
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20080254485A1 (en) * | 2006-11-14 | 2008-10-16 | Biosite Incorporated | Methods And Compositions For Monitoring And Risk Prediction In Cardiorenal Syndrome |
| WO2010025424A1 (en) * | 2008-08-28 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011075744A1 (en) * | 2009-12-20 | 2011-06-23 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
Also Published As
| Publication number | Publication date |
|---|---|
| CN103858008B (zh) | 2017-03-01 |
| AU2012282918A1 (en) | 2014-02-06 |
| EP2729803A4 (en) | 2015-08-05 |
| MX2014000283A (es) | 2014-05-01 |
| US20140171522A1 (en) | 2014-06-19 |
| US20160097779A1 (en) | 2016-04-07 |
| CA2841880A1 (en) | 2013-01-17 |
| CN103858008A (zh) | 2014-06-11 |
| WO2013009573A1 (en) | 2013-01-17 |
| EA201490105A1 (ru) | 2014-07-30 |
| EP2729803A1 (en) | 2014-05-14 |
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