JP2014520836A5 - - Google Patents
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- Publication number
- JP2014520836A5 JP2014520836A5 JP2014519611A JP2014519611A JP2014520836A5 JP 2014520836 A5 JP2014520836 A5 JP 2014520836A5 JP 2014519611 A JP2014519611 A JP 2014519611A JP 2014519611 A JP2014519611 A JP 2014519611A JP 2014520836 A5 JP2014520836 A5 JP 2014520836A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccine composition
- nanoparticles
- composition according
- pseudoboehmite
- antigen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229960005486 vaccine Drugs 0.000 claims 14
- 239000002105 nanoparticle Substances 0.000 claims 9
- VXAUWWUXCIMFIM-UHFFFAOYSA-M aluminum;oxygen(2-);hydroxide Chemical compound [OH-].[O-2].[Al+3] VXAUWWUXCIMFIM-UHFFFAOYSA-M 0.000 claims 5
- 239000000427 antigen Substances 0.000 claims 5
- 102000036639 antigens Human genes 0.000 claims 5
- 108091007433 antigens Proteins 0.000 claims 5
- 239000002245 particle Substances 0.000 claims 4
- 229920000058 polyacrylate Polymers 0.000 claims 4
- 239000011148 porous material Substances 0.000 claims 3
- 239000002671 adjuvant Substances 0.000 claims 2
- 238000001914 filtration Methods 0.000 claims 2
- 206010022000 influenza Diseases 0.000 claims 2
- 238000004519 manufacturing process Methods 0.000 claims 2
- 206010043376 Tetanus Diseases 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR1156398A FR2977800B1 (fr) | 2011-07-13 | 2011-07-13 | Composition vaccinale avec des nanoparticules d'hydroxyde d'aluminium |
| FR1156398 | 2011-07-13 | ||
| PCT/FR2012/051648 WO2013007956A1 (fr) | 2011-07-13 | 2012-07-12 | Composition vaccinale avec des nanoparticules d'hydroxyde d'aluminium |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014520836A JP2014520836A (ja) | 2014-08-25 |
| JP2014520836A5 true JP2014520836A5 (cg-RX-API-DMAC7.html) | 2015-08-27 |
| JP6111245B2 JP6111245B2 (ja) | 2017-04-05 |
Family
ID=46639612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014519611A Expired - Fee Related JP6111245B2 (ja) | 2011-07-13 | 2012-07-12 | 水酸化アルミニウムナノ粒子を含むワクチン組成物 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9770505B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2731622B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6111245B2 (cg-RX-API-DMAC7.html) |
| CN (1) | CN103826658A (cg-RX-API-DMAC7.html) |
| CA (1) | CA2838817A1 (cg-RX-API-DMAC7.html) |
| ES (1) | ES2650740T3 (cg-RX-API-DMAC7.html) |
| FR (1) | FR2977800B1 (cg-RX-API-DMAC7.html) |
| NO (1) | NO2731622T3 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2013007956A1 (cg-RX-API-DMAC7.html) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104587464B (zh) * | 2015-01-23 | 2018-05-22 | 四川大学 | 一种基于氢氧化铝纳米粒的疫苗载体 |
| CN106177939B (zh) * | 2015-06-01 | 2021-01-19 | 普莱柯生物工程股份有限公司 | 一种疫苗用佐剂及其应用 |
| CN106421775B (zh) * | 2015-08-12 | 2020-12-01 | 普莱柯生物工程股份有限公司 | 一种疫苗用佐剂及含该佐剂的疫苗组合物和其应用 |
| US11344491B2 (en) * | 2015-09-23 | 2022-05-31 | The Regents Of The University Of California | Compositions and methods of using the same for decontamination of skin |
| CN107041952B (zh) * | 2016-02-05 | 2020-11-10 | 中国人民解放军军事医学科学院微生物流行病研究所 | 表面修饰有氧化铝的疫苗及其制备方法和疫苗组合物 |
| EP3463300A1 (en) * | 2016-06-01 | 2019-04-10 | Infectious Disease Research Institute | Nanoalum particles containing a sizing agent |
| CN113666404B (zh) * | 2021-09-23 | 2023-07-28 | 北京智飞绿竹生物制药有限公司 | 一种适合规模化生产的高浓度纳米级氢氧化铝佐剂配制方法 |
| CN118846101A (zh) * | 2022-02-18 | 2024-10-29 | 广州瑞贝斯药业有限公司 | 一种铝纳米晶复合免疫药物及其制备方法和应用 |
| GB202215072D0 (en) * | 2022-10-13 | 2022-11-30 | Glaxosmithkline Biologicals Sa | Process for production of aluminium hydroxide particles |
| CN115944723A (zh) * | 2022-12-22 | 2023-04-11 | 中国人民解放军陆军军医大学 | 基于纳米铝盐与纳米乳的复合物在制备疫苗佐剂中的应用及其产品 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK143689C (da) * | 1975-03-20 | 1982-03-15 | J Kreuter | Fremgangsmaade til fremstilling af en adsorberet vaccine |
| US4836948A (en) * | 1987-12-30 | 1989-06-06 | Lever Brothers Company | Viscoelastic gel detergent compositions |
| NZ259285A (en) * | 1993-01-08 | 1996-07-26 | Csl Ltd | Vaccine preparations in stable particulate form comprising an immunogen absorbed to an aluminium salt adjuvant or biodegradable polymer matrix |
| US7357936B1 (en) * | 1998-10-16 | 2008-04-15 | Smithkline Beecham Biologicals, Sa | Adjuvant systems and vaccines |
| GB0118249D0 (en) * | 2001-07-26 | 2001-09-19 | Chiron Spa | Histidine vaccines |
| CN101370515A (zh) * | 2005-11-04 | 2009-02-18 | 诺华疫苗和诊断有限公司 | 包含颗粒佐剂和免疫增强剂组合的流感疫苗 |
| ATE539765T1 (de) * | 2005-11-04 | 2012-01-15 | Novartis Vaccines & Diagnostic | Grippeimpfstoffe mit kombinationen aus teilchenförmigen adjuvantien und immunverstärkern |
| US8354110B2 (en) * | 2007-03-07 | 2013-01-15 | Uti Limited Partnership | Compositions and methods for the prevention and treatment of autoimmune conditions |
| CN101801343A (zh) * | 2007-07-26 | 2010-08-11 | 圣诺菲·帕斯图尔有限公司 | 抗原佐剂组合物及其方法 |
| DK2510947T3 (en) * | 2009-04-14 | 2016-03-21 | Glaxosmithkline Biolog Sa | Compositions for Immunization against Staphylococcus aureus. |
-
2011
- 2011-07-13 FR FR1156398A patent/FR2977800B1/fr not_active Expired - Fee Related
-
2012
- 2012-07-12 EP EP12744086.5A patent/EP2731622B1/fr not_active Not-in-force
- 2012-07-12 WO PCT/FR2012/051648 patent/WO2013007956A1/fr not_active Ceased
- 2012-07-12 US US14/131,616 patent/US9770505B2/en not_active Expired - Fee Related
- 2012-07-12 NO NO12744086A patent/NO2731622T3/no unknown
- 2012-07-12 CN CN201280034602.8A patent/CN103826658A/zh active Pending
- 2012-07-12 CA CA2838817A patent/CA2838817A1/fr not_active Abandoned
- 2012-07-12 JP JP2014519611A patent/JP6111245B2/ja not_active Expired - Fee Related
- 2012-07-12 ES ES12744086.5T patent/ES2650740T3/es active Active
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