JP2014520825A - モノクローナル抗体に対して特異的なβ−アミロイドx−37およびその使用 - Google Patents

モノクローナル抗体に対して特異的なβ−アミロイドx−37およびその使用 Download PDF

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JP2014520825A
JP2014520825A JP2014519503A JP2014519503A JP2014520825A JP 2014520825 A JP2014520825 A JP 2014520825A JP 2014519503 A JP2014519503 A JP 2014519503A JP 2014519503 A JP2014519503 A JP 2014519503A JP 2014520825 A JP2014520825 A JP 2014520825A
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antibody
peptide
aβx
jrd
sample
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JP2014520825A5 (enExample
Inventor
ヒューバート マーケン,マーク
ボージャーズ,マリアンヌ
マリア ピエール ペラジエ ヴァンデルメーレン,マーク
ブロエック,ビアンカ ジュリア ジェイ ヴァン
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ヤンセン ファーマシューティカ エヌ.ベー.
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Publication of JP2014520825A5 publication Critical patent/JP2014520825A5/ja
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies; monoclonal antibodies per se are classified with their corresponding antigens
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2014519503A 2011-07-15 2012-07-06 モノクローナル抗体に対して特異的なβ−アミロイドx−37およびその使用 Pending JP2014520825A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP11174224 2011-07-15
EP11174224.3 2011-07-15
PCT/EP2012/063213 WO2013010812A1 (en) 2011-07-15 2012-07-06 Monoclonal antibodies specific for beta-amyloid x-37 and uses thereof

Publications (2)

Publication Number Publication Date
JP2014520825A true JP2014520825A (ja) 2014-08-25
JP2014520825A5 JP2014520825A5 (enExample) 2016-12-01

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JP2014519503A Pending JP2014520825A (ja) 2011-07-15 2012-07-06 モノクローナル抗体に対して特異的なβ−アミロイドx−37およびその使用

Country Status (8)

Country Link
US (1) US8911731B2 (enExample)
EP (1) EP2731968A1 (enExample)
JP (1) JP2014520825A (enExample)
CN (1) CN103687876A (enExample)
AU (1) AU2012286021A1 (enExample)
CA (1) CA2841093A1 (enExample)
EA (1) EA201490286A1 (enExample)
WO (1) WO2013010812A1 (enExample)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004029629A1 (en) * 2002-09-27 2004-04-08 Janssen Pharmaceutica N.V. N-11 truncated amyloid-beta nomoclonal antibodies, compositions, methods and uses
CN114478762B (zh) * 2022-02-15 2024-06-04 武汉天德生物科技有限公司 一种β-淀粉样多肽1-42单克隆抗体、ELISA试剂盒及其应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8173127B2 (en) * 1997-04-09 2012-05-08 Intellect Neurosciences, Inc. Specific antibodies to amyloid beta peptide, pharmaceutical compositions and methods of use thereof
UA91683C2 (ru) * 2004-07-30 2010-08-25 Ринат Нейросаенз Корп. Антитела, направленные против бета-амилоидного пептида, и способы их применения
UY29504A1 (es) * 2005-04-29 2006-10-31 Rinat Neuroscience Corp Anticuerpos dirigidos contra el péptido amiloide beta y métodos que utilizan los mismos.
CN101223185A (zh) * 2005-05-17 2008-07-16 萨托里医药公司 用于治疗神经变性障碍的化合物
EA021047B1 (ru) 2009-07-15 2015-03-31 Янссен Фармасьютикалз, Инк. Замещенные производные триазола и имидазола в качестве модуляторов гамма-секретазы

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
JPN5014008588; HOEGLUND K.: 'PREDICTION OF ALZHEIMER'S DISEASE USING A CEREBROSPINAL FLUID PATTERN OF C-TERMINALLY 以下備考' NEURODEGENERATIVE DISEASES V5 N5, 2008, P268-276, KARGER AG. *
JPN6016013944; IDA, N. et al.: J. Biol. Chem. Vol.271, No.37, 1996, pp.22908-22914 *
JPN6016013946; 日経バイオ最新用語辞典 第5版, 2002, 第517頁 *
JPN6016013948; GRONWALL, C. et al.: J. Biotechnol. Vol.128, 2007, pp.162-183 *
JPN6016013949; JENSEN, M. et al.: Mol. Med. Vol.6, 2000, pp.291-302 *
JPN6016013951; BIBL, M. et al.: Brain Vol.129, 2006, pp.1177-1187 *
JPN6016013952; LEE, M. et al.: Ann. Neurol. Vol.58, 2005, pp.430-435 *

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Publication number Publication date
CA2841093A1 (en) 2013-01-24
CN103687876A (zh) 2014-03-26
US20140154715A1 (en) 2014-06-05
EA201490286A1 (ru) 2014-04-30
US8911731B2 (en) 2014-12-16
AU2012286021A1 (en) 2014-01-16
EP2731968A1 (en) 2014-05-21
WO2013010812A1 (en) 2013-01-24

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