JP2014520818A - 固形美容成分の溶解特性の改良されたパーソナルケア組成物 - Google Patents
固形美容成分の溶解特性の改良されたパーソナルケア組成物 Download PDFInfo
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- JP2014520818A JP2014520818A JP2014519309A JP2014519309A JP2014520818A JP 2014520818 A JP2014520818 A JP 2014520818A JP 2014519309 A JP2014519309 A JP 2014519309A JP 2014519309 A JP2014519309 A JP 2014519309A JP 2014520818 A JP2014520818 A JP 2014520818A
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- personal care
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- solid cosmetic
- isosorbide diester
- cosmetic ingredient
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Abstract
【化1】
を有するイソソルビドジエステルを含み、式中、R’及びR”は、独立して、直鎖又は分岐鎖C1〜30鎖から選択され、飽和又は不飽和であってよい。パーソナルケア組成物は、イソソルビドジエステルに可溶性の固形美容成分及び皮膚科学的に許容可能なキャリアも含む。パーソナルケア組成物は、エマルションの形態であってよい。また、次式:
【化2】
を有するイソソルビドジエステルを含むパーソナルケア組成物も開示され、式中、R’及びR”は、独立して、直鎖又は分岐鎖C1〜30鎖から選択され、飽和又は不飽和であってよく、かつZ1〜Z6は、独立して、水素、ヒドロキシル、アミノ、アミド、R’、又はR”から選択される。前述のパーソナルケア組成物の製造方法も開示される。
Description
本発明は部分的には、イソソルビドジエステルと、イソソルビドジエステルに可溶性の固形美容成分と、を含む、パーソナルケア組成物に関する。驚くべきことに、イソソルビドジエステルは、特定の固形美容成分に好適な溶媒であることが判明している。イソソルビドジエステルは、特定の例において、固形美容成分と合わせて幅広く使用されている従来の多くの溶媒と同様又はそれ以上に良好に機能する。
パーソナルケア組成物は、スキンケア、制汗剤、脱臭剤、美容品及びヘアケア製品であってよい。パーソナルケア組成物の主な用途は、保湿剤、コンディショナー、老化防止化合物、美白剤、サンレス・タナー、日焼け止め剤、制汗剤、ひげそり用組成物、ひげそり後用組成物、ファンデーション、リップスティック、整髪料、シャンプー、洗浄剤、及びこれらの組み合わせなどである。
パーソナルケア組成物は、イソソルビドジエステルを含む。イソソルビドジエステルは次式[I]:
パーソナルケア組成物は、イソソルビドジエステルに可溶性の少なくとも1つの固形(周囲条件下で)美容成分を含む。固形美容成分は、周囲条件下で固体である。固形美容成分は有機分子であってよい。固形美容成分は、非水溶性であってよい(すなわち、水溶性ビタミンなどの親水性有効成分は除外される)。好適な固形美容成分としては、フラボノイド及びテトラヒドロクルクミノイドなどのポリフェノール;ヒドロキシ酸;N−アシルアミノ酸化合物;フィトステロール;ヘキシルレゾルシノール;トコフェロールコハク酸エステル;及びグリチルレチン酸が挙げられる。ケラチン組織に固形美容成分を送達するため、固形美容成分は実質的に又は完全に溶解させることができ、すなわちこの場合、固形美容成分はパーソナルケア組成物中で固体又は結晶形態をとどめていない。
パーソナルケア組成物は、1つ以上のキャリアを含み得る。キャリアは、安定性、美観及び/又はパーソナルケア組成物中に存在する他の成分との相溶性などの点から選択することができる。
R3SiO[R2SiO]xSiR3
により表され、式中、Rは独立して水素又はC1〜30直鎖又は分岐鎖鎖飽和又は不飽和アルキル、フェニル又はアリール、トリアルキルシロキシから選択され、xは所望の分子を得るために選択された0〜約10,000の整数である。特定の実施形態では、Rは水素、メチル、又はエチルである。市販のポリシロキサンとしては、ジメチコーンとしても既知である、ポリジメチルシロキサンが挙げられ、その例としては、Shin−Etsuから販売されているDM−Fluidシリーズ、Momentive Performance Materials Inc.から販売されているVicasil(登録商標)シリーズ、及びDow Corning Corporationから販売されるDow Corning(登録商標)200シリーズが挙げられる。好適なポリジメチルシロキサンの具体例としては、6.5E−7、1.5E−6、5E−5、0.0001、0.00035、0.01、0.0125、0.1及び0.3m2/s(0.65、1.5、50、100、350、10,000、12,500、100,000及び300,000センチストークス)の粘度を有するDow Corning(登録商標)200流体(Xiameter(登録商標)PMX−200シリコーン流体としても販売されている)が挙げられる。
R3SiO[R2SiO]x[RR’SiO]ySiR3
により表されるものが挙げられ、式中、R及びR’は各々独立して水素又はC1〜30直鎖又は分岐鎖の、飽和又は不飽和アルキル、アリール、又はトリアルキルシロキシであり、x及びyはそれぞれ所望の分子を得るために選択された1〜1,000,000の整数である。好適なシリコーンとしては、フェニルジメチコン(Botanigenics,Inc.のBotansil(商標)PD−151)、ジフェニルジメチコン(信越化学工業のKF−53及びKF−54)、フェニルトリメチコン(Dow Corningの556コスメチック・グレード液)、又はトリメチルシロキシフェニルジメチコン(Wacker−BelsilのPDM−20、PDM−200、又はPDM−1000)が挙げられる。他の例としては、少なくともR’が脂肪族アルキル(例えば、C12〜22)であるアルキルジメチコンである。好適なアルキルジメチコンはセチルジメチコンであり、式中、R’は直鎖C16鎖であり、Rはメチルである。セチルジメチコンは、2502コスメチック・フルイドとしてDow Corningから、あるいはAbil Wax 9801又は9814としてEvonik Goldschmidt GmbHから入手可能である。
パーソナルケア組成物には、1つ以上の追加成分を含有させることもできる。
本発明のパーソナルケア組成物は、数多くのケラチン組織の状態を改善又は調節するのに有用である。パーソナルケア組成物の使用法に関して使用するとき、「調節する」は、外観及び/又は触感にわずかな劣化を有するあるいはまったく劣化を有さないケラチン組織の外観及び/又は触感を維持することを意味し、「改善する」は、ケラチン組織の外観及び/又は触感に好ましい変化を生じさせるよう作用することを意味する。ケラチン組織の外観及び/又は触感効果は、即時的効果又は持続的効果であってよい。他の実施形態では、パーソナルケア組成物は、ケラチン組織に生理学的な変化を生じさせ得る。
上記の通り、パーソナルケア組成物は多様な形態を取り得る。以降の手法は例示的なものであり、限定するものとして読まれるものではない。パーソナルケア組成物が油分散体又は溶液の形態である場合、以降の手法を使用することができる。十分な量のイソソルビドジエステルを提供し、固形美容成分を可溶化させる。適切な容器中で、固形美容成分をイソソルビドジエステルと組み合わせる。組み合わせたものを混合し(例えば、撹拌棒を入れた電磁攪拌器)、所望により70℃に加熱する。可溶性及び/又は相溶性の追加成分を加えてもよい。溶質が視認されなくなるまで組成物を混合する。当該技術分野で既知の装置及び手法により混合又は均質化することができる。好適な方法及び装置としては、ミキサー又は振とうプレートなどの機械による手法、ソノレーター(sonolator)又は液体ホイッスルなどの高圧による手法、及び超音波処理器などの超音波による手法が挙げられる。典型的には、混合及び所望により70℃での加熱が、10分以下で行われる。場合により組成物を適切な容器に移す。組成物を冷却させてもよい。
2 Seppic(商標)のポリアクリルアミド、C13〜14イソパラフィン及びラウレス−7
3 Equistar(商標)のポリエチレンホモポリマースフェア
4 Dow Corning(商標)のジメチコン及びジメチコノール
5 BASF(商標)のビス−エチルヘキシルオキシフェノールメトキシフェニルトリアジン
6 Syntheon,Ltd.(Boonton,NJ)のジオクタノイルイソソルビド
7 Girindus America,Inc.(Reading,OH)から入手可能
8 Sabinsa Corporation(East Windsor,NJ)から入手可能
9 Sytheon,Ltd.(Lincoln Park,NJ)から入手可能Synovea(登録商標)HR
以降の試験において、試験する固形の溶質の溶解性に関し、「可溶性」(又は「可溶化する」)とは、貯蔵条件下での規定の貯蔵期間後に視認可能な結晶が確認されないことを意味する。貯蔵期間は変更することができる。好適な貯蔵期間は、約24時間、約1週間及び約30日間である。好適な貯蔵条件としては、周囲条件又は5℃での冷蔵条件が挙げられる(約101.3kPa(1atm))。特定の実施形態では、溶解度は、周囲条件下で24時間経過後に評価することができる。他の実施形態では、溶解度は、冷蔵条件下で20日後に評価することができる。他の試験パラメーターとしては、より長期間の貯蔵(例えば、30日間、50日間、60日間、90日間)及び各種温度(例えば、5℃、50℃)が挙げられる。
Claims (29)
- R’及びR”が同じである、請求項1に記載のパーソナルケア組成物。
- R’及びR”が、飽和直鎖又は分岐鎖のC7鎖である、請求項1に記載のパーソナルケア組成物。
- R’及びR”が、飽和直鎖のC7鎖である、請求項3に記載のパーソナルケア組成物。
- 前記固形美容成分を約0.1%〜約10%含む、請求項1に記載のパーソナルケア組成物。
- 前記固形美容成分が、フラボノイド、ヒドロキシ酸、N−アシルアミノ酸化合物、フィトステロール、グリチルレチン酸、トコフェロールスクシネート、及びこれらの組み合わせからなる群から選択される固形化合物である、請求項1に記載のパーソナルケア組成物。
- 前記固形美容成分が、ヘキシルレゾルシノール、エクオル、テトラヒドロクルクミノイド、非置換フラボン、7,2’−ジヒドロキシフラボン、3’,4’−ジヒドロキシナフトフラボン、4’−ヒドロキシフラボン、5,6−ベンゾフラボン、及び7,8−ベンゾフラボン、非置換イソフラボン、7,4’−ジヒドロキシイソフラボン、5,7−ジヒドロキシ−4’−メトキシイソフラボン、大豆イソフラボン、サリチル酸、β−シトステロール、カンペステロール、ブラシカステロール、δ−5−アベナステロール(avennasterol)、ルペノール、α−スピナステロール、スティグマステロール、グリチルレチン酸(glycyrretinic acid)、ウンデシレノイルフェニルアラニン、ビタミンEコハク酸塩、及びこれらの組み合わせからなる群から選択される、請求項1に記載のパーソナルケア組成物。
- 前記固形美容成分が、ヘキシルレゾルシノール、エクオル、テトラヒドロクルクミノイド、及びこれらの組み合わせからなる群から選択される、請求項1に記載のパーソナルケア組成物。
- 前記イソソルビドジエステルを、前記固形美容成分を実質的に可溶化するのに十分な量で含む、請求項1に記載のパーソナルケア組成物。
- 固形美容成分1重量部毎に、少なくとも2重量部のイソソルビドジエステルを含む、請求項1に記載のパーソナルケア組成物。
- 固形美容成分1重量部毎に、少なくとも5重量部のイソソルビドジエステルを含む、請求項1に記載のパーソナルケア組成物。
- 固形美容成分1重量部毎に、少なくとも10重量部のイソソルビドジエステルを含む、請求項1に記載のパーソナルケア組成物。
- UV有効成分を更に含む、請求項1に記載のパーソナルケア組成物。
- 前記UV有効成分が、4−tert−ブチル−4’−メトキシジベンゾイルメタン、ビス−エチルヘキシルオキシフェノールメトキシフェニルトリアジン、2,4,6−トリアニリノ−(p−カルボ−2’−エチルヘキシル−1’−オキシ)−1,3,5−トリアジン、ジエチルヘキシルブタミドトリアゾン、ジエチルアミノヒドロキシベンゾイルヘキシルベンゾエート、ベンゾフェノン−3、4−メチルベンジリデンカンファー、エチルヘキシルビス−イソペンチルベンゾオキサゾリルフェニルメラミン、及びこれらの組み合わせから選択される固形UV有効成分である、請求項13に記載のパーソナルケア組成物。
- 前記UV有効成分が、2−エチルヘキシル−p−メトキシシンナメート、オクチルジメチル−p−アミノ安息香酸、2−エチルヘキシル−2−シアノ−3,3−ジフェニルアクリレート、2−エチルヘキシルサリチレート、2−フェニルベンゾイミダゾール−5−スルホン酸、2−(p−ジメチルアミノフェニル)−5−スルホンベンゾオキサゾイン酸、フェニルジベンゾイミダゾールテトラスルホン酸二ナトリウム、ジヒドロキシジメトキシジスルホベンゾフェノンナトリウム、ポリシリコーン−15、イソアミルp−メトキシシンナメート、二酸化チタン、酸化亜鉛、メチレンビス−ベンゾトリアゾリルテトラメチルブチルフェノール、及びこれらの組み合わせから選択される、請求項13に記載のパーソナルケア組成物。
- 前記UV有効成分が、4−tert−ブチル−4’−メトキシジベンゾイルメタン、2−エチルヘキシル−2−シアノ−3,3−ジフェニルアクリレート、及びこれらの組み合わせから選択される、請求項15に記載のパーソナルケア組成物。
- 光安定剤を更に含む、請求項1に記載のパーソナルケア組成物。
- 前記光安定剤が、メトキシクリレン、ジエチルヘキシル2,6−ナフタレート、ジエチルヘキシルシリンジリデンマロネート、及びこれらの組み合わせからなる群から選択される、請求項17に記載のパーソナルケア組成物。
- UV有効成分1重量部毎に光安定剤が少なくとも1重量部の比で光安定剤を更に含む、請求項13に記載のパーソナルケア組成物。
- a.水を含む水相と、
b.前記イソソルビドジエステルと前記イソソルビドジエステルに可溶性の前記固形美容成分とを含む油相と、を含むエマルション形態である、請求項1に記載のパーソナルケア組成物。 - 前記油相を、前記パーソナルケア組成物の少なくとも1重量%の水を含む水相と組み合わせる工程を更に含む、請求項22に記載の方法。
- 前記固形美容成分が、ヘキシルレゾルシノール、エクオル、テトラヒドロクルクミノイド、非置換フラボン、7,2’−ジヒドロキシフラボン、3’,4’−ジヒドロキシナフトフラボン、4’−ヒドロキシフラボン、5,6−ベンゾフラボン、及び7,8−ベンゾフラボン,非置換イソフラボン、7,4’−ジヒドロキシイソフラボン、5,7−ジヒドロキシ−4’−メトキシイソフラボン、大豆イソフラボン、サリチル酸、β−シトステロール、カンペステロール、ブラシカステロール、δ−5−アベナステロール(avennasterol)、ルペノール、α−スピナステロール、スティグマステロール、グリチルレチン酸(glycyrretinic acid)、ウンデシレノイルフェニルアラニン、ビタミンEコハク酸塩、及びこれらの組み合わせからなる群から選択される、請求項22に記載の方法。
- 前記固形美容成分が、ヘキシルレゾルシノール、エクオル、テトラヒドロクルクミノイド、及びこれらの組み合わせからなる群から選択される、請求項22に記載の方法。
- R’及びR”が同じである、請求項22に記載の方法。
- R’及びR”が飽和直鎖又は分岐鎖のC7鎖である、請求項22に記載の方法。
- R’及びR”が飽和直鎖のC7鎖である、請求項22に記載の方法。
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US13/177,880 US20130011347A1 (en) | 2011-07-07 | 2011-07-07 | Personal Care Compositions With Improved Solubility of a Solid Cosmetic Active |
US13/177,880 | 2011-07-07 | ||
PCT/US2012/045646 WO2013006743A2 (en) | 2011-07-07 | 2012-07-06 | Personal care compositions with improved solubility of a solid cosmetic active |
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EP (1) | EP2729113A2 (ja) |
JP (1) | JP2014520818A (ja) |
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JP2015159774A (ja) * | 2014-02-28 | 2015-09-07 | 不二製油株式会社 | 接触性皮膚炎を抑制する食品添加用組成物 |
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CN111888277B (zh) * | 2019-05-06 | 2021-05-04 | 太和康美(北京)中医研究院有限公司 | 化妆品用植物甾醇组合物及其制备方法和用途 |
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EP2729113A2 (en) | 2014-05-14 |
WO2013006743A2 (en) | 2013-01-10 |
WO2013006743A3 (en) | 2014-04-17 |
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