JP2014517694A5 - - Google Patents
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- Publication number
- JP2014517694A5 JP2014517694A5 JP2014512189A JP2014512189A JP2014517694A5 JP 2014517694 A5 JP2014517694 A5 JP 2014517694A5 JP 2014512189 A JP2014512189 A JP 2014512189A JP 2014512189 A JP2014512189 A JP 2014512189A JP 2014517694 A5 JP2014517694 A5 JP 2014517694A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- nucleic acid
- acid sequence
- vector
- viral vector
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 14
- 239000013603 viral vector Substances 0.000 claims 12
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 11
- 150000007523 nucleic acids Chemical group 0.000 claims 11
- 239000013598 vector Substances 0.000 claims 5
- 102000000505 Ribonucleotide Reductases Human genes 0.000 claims 3
- 108010041388 Ribonucleotide Reductases Proteins 0.000 claims 3
- 241000124008 Mammalia Species 0.000 claims 2
- 125000003275 alpha amino acid group Chemical group 0.000 claims 2
- 238000006467 substitution reaction Methods 0.000 claims 2
- 241000702421 Dependoparvovirus Species 0.000 claims 1
- 102000004316 Oxidoreductases Human genes 0.000 claims 1
- 108090000854 Oxidoreductases Proteins 0.000 claims 1
- 108091028664 Ribonucleotide Proteins 0.000 claims 1
- 230000000747 cardiac effect Effects 0.000 claims 1
- 230000004217 heart function Effects 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 210000004165 myocardium Anatomy 0.000 claims 1
- 239000002336 ribonucleotide Substances 0.000 claims 1
- 125000002652 ribonucleotide group Chemical group 0.000 claims 1
- 102220082801 rs572004966 Human genes 0.000 claims 1
- 102220032023 rs72554321 Human genes 0.000 claims 1
- 230000026683 transduction Effects 0.000 claims 1
- 238000010361 transduction Methods 0.000 claims 1
- 210000003462 vein Anatomy 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161490450P | 2011-05-26 | 2011-05-26 | |
| US61/490,450 | 2011-05-26 | ||
| PCT/US2012/039897 WO2012162705A2 (en) | 2011-05-26 | 2012-05-29 | Cell and gene based methods to improve cardiac function |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014517694A JP2014517694A (ja) | 2014-07-24 |
| JP2014517694A5 true JP2014517694A5 (cg-RX-API-DMAC7.html) | 2015-07-16 |
| JP6162104B2 JP6162104B2 (ja) | 2017-07-12 |
Family
ID=47218136
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014512189A Active JP6162104B2 (ja) | 2011-05-26 | 2012-05-29 | 細胞及び遺伝子に基づく心臓機能改善方法 |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US9868937B2 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2714709B1 (cg-RX-API-DMAC7.html) |
| JP (1) | JP6162104B2 (cg-RX-API-DMAC7.html) |
| KR (1) | KR20140035967A (cg-RX-API-DMAC7.html) |
| CN (1) | CN103946230B (cg-RX-API-DMAC7.html) |
| AU (1) | AU2012258525B2 (cg-RX-API-DMAC7.html) |
| BR (1) | BR112013030209A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2837322C (cg-RX-API-DMAC7.html) |
| RU (1) | RU2608957C2 (cg-RX-API-DMAC7.html) |
| WO (1) | WO2012162705A2 (cg-RX-API-DMAC7.html) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9868937B2 (en) | 2011-05-26 | 2018-01-16 | University Of Washington | Cell and gene based methods to improve cardiac function |
| EP2792742A1 (en) | 2013-04-17 | 2014-10-22 | Universitätsklinikum Hamburg-Eppendorf (UKE) | Gene-therapy vectors for treating cardiomyopathy |
| WO2015153357A1 (en) * | 2014-03-29 | 2015-10-08 | Beat Biotherapeutics Corp. | Compositions and methods for improving cardiac function |
| IL286316B2 (en) * | 2015-01-16 | 2023-03-01 | Univ Washington | New micro-dystrophins and related method of use |
| EP3268481B1 (en) | 2015-03-11 | 2020-05-27 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Rpgr vectors for treating x-linked retinitis pigmentosa |
| WO2017031238A2 (en) | 2015-08-18 | 2017-02-23 | Boston Scientific Scimed Inc. | Methods for producing cardiomyocyte cells |
| CA3089957C (en) * | 2017-02-04 | 2024-01-23 | AnaBios Corporation | System and methods for predicting drug-induced inotropic and pro-arrhythmia risk |
| CN108913655B (zh) * | 2018-07-16 | 2022-07-15 | 浙江大学 | 基于多能干细胞技术建立“人源性”心肌肥大模型的方法 |
| KR20210052389A (ko) | 2018-08-27 | 2021-05-10 | 리제너론 파마슈티칼스 인코포레이티드 | 다운스트림 정제에서의 라만 분광법의 사용 |
| KR20210102870A (ko) | 2018-08-30 | 2021-08-20 | 테나야 테라퓨틱스, 인코포레이티드 | 미오카르딘 및 ascl1을 사용한 심장 세포 재프로그래밍 |
| US20200405824A1 (en) * | 2019-06-26 | 2020-12-31 | University Of Washington | Use of ribonucleotide reductase alone or in combination with micro-dystrophin to treat duchenne muscular dystrophy striated muscle disease |
| CN110384800B (zh) * | 2019-07-19 | 2021-06-08 | 广东省实验动物监测所 | LncRNA XLOC_075168在制备促进血管新生的药物中的应用 |
| IL295529A (en) | 2020-02-13 | 2022-10-01 | Tenaya Therapeutics Inc | Gene therapy vectors for treating heart disease |
| WO2022216800A1 (en) * | 2021-04-06 | 2022-10-13 | University Of Washington | Non-contractile cardiomyocytes for cardiac repair |
| CN120758566B (zh) * | 2025-09-10 | 2025-11-21 | 瓯江实验室 | 一种在心肌细胞中特异性过表达zer1的病毒载体的构建及在心衰治疗中的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH02240440A (ja) | 1989-03-14 | 1990-09-25 | Shiigeru:Kk | 慣性ダンパ |
| GB9022543D0 (en) * | 1990-10-17 | 1990-11-28 | Wellcome Found | Antibody production |
| US6151525A (en) * | 1997-11-07 | 2000-11-21 | Medtronic, Inc. | Method and system for myocardial identifier repair |
| EP1085910A2 (en) * | 1998-05-30 | 2001-03-28 | Collateral Therapeutics, Inc. | Methods of altering cardiac cell phenotype |
| US6451594B1 (en) * | 1998-09-11 | 2002-09-17 | The Regents Of The University Of California | Recombinant adenovirus for tissue specific expression in heart |
| JP2002533359A (ja) | 1998-12-28 | 2002-10-08 | アーチ ディベロップメント コーポレイション | 組換えアデノ随伴ウイルスベクターを用いる、心筋細胞への効率的かつ安定なインビボでの遺伝子移入 |
| AU2002230999A1 (en) | 2000-12-21 | 2002-07-01 | Medtronic, Inc. | Electrically responsive promoter system |
| WO2003094697A2 (en) * | 2002-05-08 | 2003-11-20 | The Regents Of The University Of California | Methods and compositions for correction of cardiac conduction disturbances |
| AU2003270544A1 (en) * | 2002-09-11 | 2004-04-30 | University Of Florida | Vigilant vector system |
| US20070238675A1 (en) * | 2003-08-11 | 2007-10-11 | Phillips M I | Stem Cell Beacon |
| CN1882687B (zh) * | 2003-11-21 | 2012-07-04 | 第一三共株式会社 | 心肌细胞的增殖方法 |
| US20050260637A1 (en) * | 2004-03-25 | 2005-11-24 | Yun Yen | Drug screening |
| DE102011018586A1 (de) * | 2011-04-26 | 2012-10-31 | Oliver Müller | Vektorsystem zur spezifischen Genexpression im Herzmuskel |
| US9868937B2 (en) | 2011-05-26 | 2018-01-16 | University Of Washington | Cell and gene based methods to improve cardiac function |
-
2012
- 2012-05-29 US US14/122,226 patent/US9868937B2/en active Active
- 2012-05-29 RU RU2013157590A patent/RU2608957C2/ru not_active IP Right Cessation
- 2012-05-29 KR KR1020137034630A patent/KR20140035967A/ko not_active Ceased
- 2012-05-29 CA CA2837322A patent/CA2837322C/en active Active
- 2012-05-29 JP JP2014512189A patent/JP6162104B2/ja active Active
- 2012-05-29 EP EP12790042.1A patent/EP2714709B1/en active Active
- 2012-05-29 BR BR112013030209A patent/BR112013030209A2/pt not_active Application Discontinuation
- 2012-05-29 WO PCT/US2012/039897 patent/WO2012162705A2/en not_active Ceased
- 2012-05-29 AU AU2012258525A patent/AU2012258525B2/en active Active
- 2012-05-29 CN CN201280034527.5A patent/CN103946230B/zh not_active Expired - Fee Related
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