JP2014516947A5 - - Google Patents
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- Publication number
- JP2014516947A5 JP2014516947A5 JP2014509331A JP2014509331A JP2014516947A5 JP 2014516947 A5 JP2014516947 A5 JP 2014516947A5 JP 2014509331 A JP2014509331 A JP 2014509331A JP 2014509331 A JP2014509331 A JP 2014509331A JP 2014516947 A5 JP2014516947 A5 JP 2014516947A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- compound
- enzyme
- light
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 0 Cc1cc(*)ccc1 Chemical compound Cc1cc(*)ccc1 0.000 description 6
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161482134P | 2011-05-03 | 2011-05-03 | |
| US61/482,134 | 2011-05-03 | ||
| PCT/US2012/035732 WO2012151142A2 (en) | 2011-05-03 | 2012-04-30 | Flash and glow 1,2-dioxetanes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016192667A Division JP6440265B2 (ja) | 2011-05-03 | 2016-09-30 | フラッシュ・グロー型の１，２−ジオキセタン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014516947A JP2014516947A (ja) | 2014-07-17 |
| JP2014516947A5 true JP2014516947A5 (https=) | 2015-05-07 |
Family
ID=46085191
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014509331A Pending JP2014516947A (ja) | 2011-05-03 | 2012-04-30 | フラッシュ・グロー型の１，２−ジオキセタン |
| JP2016192667A Active JP6440265B2 (ja) | 2011-05-03 | 2016-09-30 | フラッシュ・グロー型の１，２−ジオキセタン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016192667A Active JP6440265B2 (ja) | 2011-05-03 | 2016-09-30 | フラッシュ・グロー型の１，２−ジオキセタン |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20140154675A1 (https=) |
| EP (1) | EP2705031B1 (https=) |
| JP (2) | JP2014516947A (https=) |
| KR (1) | KR101960113B1 (https=) |
| CN (1) | CN103649069B (https=) |
| WO (1) | WO2012151142A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3211050A1 (en) * | 2016-02-26 | 2017-08-30 | Trinseo Europe GmbH | Molded structures of polycarbonate based substrates over molded with silicone rubbers |
| EP3510040A4 (en) | 2016-09-09 | 2020-06-03 | Calithera Biosciences, Inc. | EKTONUCLEOTIDASE INHIBITORS AND METHOD FOR USE THEREOF |
| KR102638592B1 (ko) | 2016-12-22 | 2024-02-19 | 안텐진 테라퓨틱스 리미티드 | 엑토뉴클레오티다제 억제제 및 이의 용도 |
| SG11202012001YA (en) | 2018-06-21 | 2021-01-28 | Calithera Biosciences Inc | Ectonucleotidase inhibitors and methods of use thereof |
| CN114867716B (zh) * | 2019-10-28 | 2025-11-07 | 贝克曼库尔特有限公司 | 快速、高强度的化学发光二氧杂环丁烷 |
| WO2025160017A1 (en) * | 2024-01-26 | 2025-07-31 | Beckman Coulter, Inc. | Assay methods using chemiluminescent dioxetane compounds |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340590C (en) | 1986-07-24 | 1999-06-08 | John C. Voyta | Chemiluminescence enhancement |
| US5538847A (en) * | 1989-07-17 | 1996-07-23 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
| US5582980A (en) * | 1989-07-17 | 1996-12-10 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
| US4952707A (en) * | 1988-06-30 | 1990-08-28 | Tropix, Inc. | Enzymatically-cleavable chemiluminescent fused polycyclic ring-containing 1,2-dioxetanes |
| US5326882A (en) * | 1989-07-17 | 1994-07-05 | Tropix, Inc. | Chemiluminescent 3-(substituted Adamant-2'-Ylidene) 1,2-dioxetanes |
| US5547836A (en) | 1990-08-30 | 1996-08-20 | Tropix, Inc. | Enhancement of chemiluminescent assays |
| US5994073A (en) | 1990-08-30 | 1999-11-30 | Tropix, Inc. | Enhancement of chemiluminescent assays |
| US5603868A (en) * | 1992-10-30 | 1997-02-18 | Abbott Laboratories | Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes |
| US5773628A (en) * | 1994-11-14 | 1998-06-30 | Tropix, Inc. | 1,2-dioxetane compounds with haloalkoxy groups, methods preparation and use |
| EP0809804A4 (en) * | 1995-02-13 | 1999-03-31 | Tropix Inc | Chemiluminescent energy transfer assays |
| JPH08245615A (ja) * | 1995-03-11 | 1996-09-24 | Masakatsu Matsumoto | １，２−ジオキセタン誘導体 |
| JP3855033B2 (ja) * | 1995-09-08 | 2006-12-06 | 高砂香料工業株式会社 | 光学活性３−ヒドロキシ−γ−ブチロラクトンの製造方法 |
| US5679803A (en) * | 1995-10-25 | 1997-10-21 | Tropix, Inc. | 1,2 chemiluminescent dioxetanes of improved performance |
| DE69622605T2 (de) * | 1995-10-17 | 2003-03-13 | Tropix, Inc. | Chemilumineszente 1,2-dioxetane mit verbesserter leistung |
| AU5237699A (en) * | 1998-07-28 | 2000-02-21 | Tropix, Inc. | Benzothiazole dioxetanes |
| US6660529B2 (en) * | 1998-07-28 | 2003-12-09 | Pe Corporation | Heteroaryl substituted benzothiazole dioxetanes |
| CN1211387C (zh) * | 1998-09-08 | 2005-07-20 | 布里奇·P·吉利 | 化学发光的1,2－二氧丁环 |
| US7416898B2 (en) * | 2002-10-04 | 2008-08-26 | Giri Brij P | Chemiluminescent 1,2-dioxetanes |
| EP1735621A4 (en) * | 2004-04-14 | 2012-12-12 | Brij P Giri | NEW ULTRA-SENSITIVE CHEMIELUMINESCENSE SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES |
| US20060079699A1 (en) * | 2004-08-27 | 2006-04-13 | Brooks Edwards | Intermediate compounds and methods for synthesizing chemiluminescent dioxetane substrates |
| EP1787365A4 (en) * | 2004-09-09 | 2009-10-21 | Applera Corp | DIOXETANNANOPARTICLE ARRANGEMENTS FOR ENERGY TRANSMISSION DETECTION SYSTEMS, METHOD FOR MANUFACTURING THE ARRANGEMENTS, AND METHOD FOR USING THE ORGANIZATIONS IN BIOTESTS |
| EP2390663B1 (en) * | 2007-05-23 | 2013-11-13 | Life Technologies Corporation | Reagents, kits and methods for detecting biological molecules by energy transfer from an activated chemiluminescent substrate to an energy acceptor dye |
| WO2009139811A2 (en) * | 2008-05-15 | 2009-11-19 | Tianxin Wang | Chemiluminescent methods and reagents for analyte detection |
| EP2403843B1 (en) * | 2009-03-02 | 2018-11-07 | Life Technologies Corporation | Chemiluminescent compositions, methods, assays and kits for oxidative enzymes |
-
2012
- 2012-04-30 JP JP2014509331A patent/JP2014516947A/ja active Pending
- 2012-04-30 EP EP12721076.3A patent/EP2705031B1/en active Active
- 2012-04-30 KR KR1020137031604A patent/KR101960113B1/ko not_active Expired - Fee Related
- 2012-04-30 WO PCT/US2012/035732 patent/WO2012151142A2/en not_active Ceased
- 2012-04-30 US US14/114,975 patent/US20140154675A1/en not_active Abandoned
- 2012-04-30 CN CN201280021603.9A patent/CN103649069B/zh active Active
-
2016
- 2016-09-30 JP JP2016192667A patent/JP6440265B2/ja active Active
-
2017
- 2017-02-17 US US15/436,491 patent/US20170321245A1/en not_active Abandoned
-
2019
- 2019-07-12 US US16/510,531 patent/US20200056222A1/en not_active Abandoned
-
2021
- 2021-07-20 US US17/380,396 patent/US20220010356A1/en not_active Abandoned
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