JP2014516947A5 - - Google Patents
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- Publication number
- JP2014516947A5 JP2014516947A5 JP2014509331A JP2014509331A JP2014516947A5 JP 2014516947 A5 JP2014516947 A5 JP 2014516947A5 JP 2014509331 A JP2014509331 A JP 2014509331A JP 2014509331 A JP2014509331 A JP 2014509331A JP 2014516947 A5 JP2014516947 A5 JP 2014516947A5
- Authority
- JP
- Japan
- Prior art keywords
- carbon atoms
- compound
- enzyme
- light
- group
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 0 Cc1cc(*)ccc1 Chemical compound Cc1cc(*)ccc1 0.000 description 6
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161482134P | 2011-05-03 | 2011-05-03 | |
| US61/482,134 | 2011-05-03 | ||
| PCT/US2012/035732 WO2012151142A2 (en) | 2011-05-03 | 2012-04-30 | Flash and glow 1,2-dioxetanes |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016192667A Division JP6440265B2 (ja) | 2011-05-03 | 2016-09-30 | フラッシュ・グロー型の１，２−ジオキセタン |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2014516947A JP2014516947A (ja) | 2014-07-17 |
| JP2014516947A5 true JP2014516947A5 (https=) | 2015-05-07 |
Family
ID=46085191
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014509331A Pending JP2014516947A (ja) | 2011-05-03 | 2012-04-30 | フラッシュ・グロー型の１，２−ジオキセタン |
| JP2016192667A Active JP6440265B2 (ja) | 2011-05-03 | 2016-09-30 | フラッシュ・グロー型の１，２−ジオキセタン |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2016192667A Active JP6440265B2 (ja) | 2011-05-03 | 2016-09-30 | フラッシュ・グロー型の１，２−ジオキセタン |
Country Status (6)
| Country | Link |
|---|---|
| US (4) | US20140154675A1 (https=) |
| EP (1) | EP2705031B1 (https=) |
| JP (2) | JP2014516947A (https=) |
| KR (1) | KR101960113B1 (https=) |
| CN (1) | CN103649069B (https=) |
| WO (1) | WO2012151142A2 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3211050A1 (en) * | 2016-02-26 | 2017-08-30 | Trinseo Europe GmbH | Molded structures of polycarbonate based substrates over molded with silicone rubbers |
| TWI767937B (zh) | 2016-09-09 | 2022-06-21 | 美商卡利泰拉生物科技公司 | 外核苷酸酶抑制劑及其使用方法 |
| JP7138351B2 (ja) | 2016-12-22 | 2022-09-16 | キャリセラ バイオサイエンシーズ， インコーポレイテッド | エクトヌクレオチダーゼ阻害剤およびその使用方法 |
| AU2019288495B2 (en) | 2018-06-21 | 2024-02-08 | Antengene Therapeutics Limited | Ectonucleotidase inhibitors and methods of use thereof |
| WO2021086977A1 (en) * | 2019-10-28 | 2021-05-06 | Beckman Coulter, Inc. | Rapid, high-intensity chemiluminescent dioxetanes |
| WO2025160017A1 (en) * | 2024-01-26 | 2025-07-31 | Beckman Coulter, Inc. | Assay methods using chemiluminescent dioxetane compounds |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1340590C (en) | 1986-07-24 | 1999-06-08 | John C. Voyta | Chemiluminescence enhancement |
| US5582980A (en) * | 1989-07-17 | 1996-12-10 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
| US5538847A (en) * | 1989-07-17 | 1996-07-23 | Tropix, Inc. | Chemiluminescent 1,2-dioxetanes |
| US4952707A (en) * | 1988-06-30 | 1990-08-28 | Tropix, Inc. | Enzymatically-cleavable chemiluminescent fused polycyclic ring-containing 1,2-dioxetanes |
| US5326882A (en) * | 1989-07-17 | 1994-07-05 | Tropix, Inc. | Chemiluminescent 3-(substituted Adamant-2'-Ylidene) 1,2-dioxetanes |
| US5547836A (en) | 1990-08-30 | 1996-08-20 | Tropix, Inc. | Enhancement of chemiluminescent assays |
| US5994073A (en) | 1990-08-30 | 1999-11-30 | Tropix, Inc. | Enhancement of chemiluminescent assays |
| US5603868A (en) * | 1992-10-30 | 1997-02-18 | Abbott Laboratories | Chemiluminescent electron-rich aryl-substituted 1,2-dioxetanes |
| US5773628A (en) * | 1994-11-14 | 1998-06-30 | Tropix, Inc. | 1,2-dioxetane compounds with haloalkoxy groups, methods preparation and use |
| JPH11500222A (ja) * | 1995-02-13 | 1999-01-06 | トロピックス・インコーポレーテッド | 化学ルミネセンスエネルギー移動アッセイ |
| JPH08245615A (ja) * | 1995-03-11 | 1996-09-24 | Masakatsu Matsumoto | １，２−ジオキセタン誘導体 |
| JP3855033B2 (ja) * | 1995-09-08 | 2006-12-06 | 高砂香料工業株式会社 | 光学活性３−ヒドロキシ−γ−ブチロラクトンの製造方法 |
| US5679803A (en) * | 1995-10-25 | 1997-10-21 | Tropix, Inc. | 1,2 chemiluminescent dioxetanes of improved performance |
| WO1997014692A1 (en) * | 1995-10-17 | 1997-04-24 | Tropix, Inc. | 1,2 chemiluminescent dioxetanes of improved performance |
| US6660529B2 (en) * | 1998-07-28 | 2003-12-09 | Pe Corporation | Heteroaryl substituted benzothiazole dioxetanes |
| CA2338883A1 (en) * | 1998-07-28 | 2000-02-10 | Tropix, Inc. | Benzothiazole dioxetanes |
| IL141830A0 (en) * | 1998-09-08 | 2002-03-10 | Giri Brij P | Chemiluminescent 1,2-dioxetane |
| US7416898B2 (en) * | 2002-10-04 | 2008-08-26 | Giri Brij P | Chemiluminescent 1,2-dioxetanes |
| EP1735621A4 (en) * | 2004-04-14 | 2012-12-12 | Brij P Giri | NEW ULTRA-SENSITIVE CHEMIELUMINESCENSE SUBSTRATES FOR ENZYMES AND THEIR CONJUGATES |
| US20060079699A1 (en) * | 2004-08-27 | 2006-04-13 | Brooks Edwards | Intermediate compounds and methods for synthesizing chemiluminescent dioxetane substrates |
| WO2006029302A2 (en) * | 2004-09-09 | 2006-03-16 | Applera Corporation | Dioxetane-nanoparticle assemblies for energy transfer detection systems, methods of making the assemblies, and methods of using the assemblies in bioassays |
| CN101784897A (zh) * | 2007-05-23 | 2010-07-21 | 应用生物系统有限公司 | 通过从活化的化学发光的基质将能量转移至能量受体染料来检测生物分子的试剂、试剂盒和方法 |
| WO2009139811A2 (en) * | 2008-05-15 | 2009-11-19 | Tianxin Wang | Chemiluminescent methods and reagents for analyte detection |
| WO2010101839A2 (en) * | 2009-03-02 | 2010-09-10 | Life Technologies Corporation | Chemiluminescent compositions, methods, assays and kits for oxidative enzymes |
-
2012
- 2012-04-30 US US14/114,975 patent/US20140154675A1/en not_active Abandoned
- 2012-04-30 WO PCT/US2012/035732 patent/WO2012151142A2/en not_active Ceased
- 2012-04-30 EP EP12721076.3A patent/EP2705031B1/en active Active
- 2012-04-30 CN CN201280021603.9A patent/CN103649069B/zh active Active
- 2012-04-30 KR KR1020137031604A patent/KR101960113B1/ko not_active Expired - Fee Related
- 2012-04-30 JP JP2014509331A patent/JP2014516947A/ja active Pending
-
2016
- 2016-09-30 JP JP2016192667A patent/JP6440265B2/ja active Active
-
2017
- 2017-02-17 US US15/436,491 patent/US20170321245A1/en not_active Abandoned
-
2019
- 2019-07-12 US US16/510,531 patent/US20200056222A1/en not_active Abandoned
-
2021
- 2021-07-20 US US17/380,396 patent/US20220010356A1/en not_active Abandoned
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