JP2014516407A5 - - Google Patents
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- Publication number
- JP2014516407A5 JP2014516407A5 JP2014503629A JP2014503629A JP2014516407A5 JP 2014516407 A5 JP2014516407 A5 JP 2014516407A5 JP 2014503629 A JP2014503629 A JP 2014503629A JP 2014503629 A JP2014503629 A JP 2014503629A JP 2014516407 A5 JP2014516407 A5 JP 2014516407A5
- Authority
- JP
- Japan
- Prior art keywords
- seq
- derived
- human
- protein
- condition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE1150299-4 | 2011-04-05 | ||
| SE1150299 | 2011-04-05 | ||
| PCT/SE2012/050352 WO2012138284A1 (en) | 2011-04-05 | 2012-03-30 | Amyloidosis target useful in methods of treatment and for screening of compounds |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2014516407A JP2014516407A (ja) | 2014-07-10 |
| JP2014516407A5 true JP2014516407A5 (enExample) | 2015-05-14 |
| JP6227523B2 JP6227523B2 (ja) | 2017-11-08 |
Family
ID=46085122
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2014503629A Expired - Fee Related JP6227523B2 (ja) | 2011-04-05 | 2012-03-30 | 治療の方法においておよび化合物のスクリーニングのために有用なアミロドーシスターゲット |
Country Status (4)
| Country | Link |
|---|---|
| US (1) | US9522170B2 (enExample) |
| EP (1) | EP2694977B1 (enExample) |
| JP (1) | JP6227523B2 (enExample) |
| WO (1) | WO2012138284A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010087771A1 (en) | 2009-01-30 | 2010-08-05 | Alphabeta Ab | Compound and method for treatment of alzheimer's disease |
| US11077095B2 (en) * | 2017-02-24 | 2021-08-03 | Alzheon, Inc. | Methods for treating neurodegenerative disorders |
| JP7820821B2 (ja) * | 2020-01-08 | 2026-02-26 | アルファベータ・エービー | アルツハイマー病の治療のための化合物及び方法 |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0290516A4 (en) | 1986-10-24 | 1989-11-14 | Jeffrey A Whitsett | PROTEINS RELATED TO SURFACE-EFFECTIVE HYDROPHOBIC LUNG ACTIVE SUBSTANCES. |
| ATE284538T1 (de) | 1998-10-30 | 2004-12-15 | Jordan L Holtzman | Komplex, bestehend aus einem chaperon und beta- amyloidprotein sowie verfahren, die diesen komplex benutzen |
| US6670195B1 (en) * | 1999-05-26 | 2003-12-30 | New York University | Mutant genes in Familial British Dementia and Familial Danish Dementia |
| US20030224982A1 (en) | 2001-07-05 | 2003-12-04 | Li Li | Therapeutic polypeptides, nucleic acids encoding same, and methods of use |
| US6673545B2 (en) | 2000-07-28 | 2004-01-06 | Incyte Corporation | Prostate cancer markers |
| US6716589B2 (en) | 2000-11-20 | 2004-04-06 | Alphabeta Ab | Discordant helix stabilization for prevention of amyloid formation |
| EP1387678A1 (en) * | 2001-05-03 | 2004-02-11 | Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. | Compounds that inhibit hsp90 and stimulate hsp70 and hsp40, useful in the prevention or treatment of diseases associated with protein aggregation and amyloid formation |
| MXPA04010560A (es) | 2002-04-25 | 2005-08-15 | Scripps Research Inst | Tratamiento y prevencion de condiciones pulmonares. |
| CA2507613A1 (en) | 2002-12-09 | 2004-07-08 | Jeffrey A. Whitsett | Methods of diagnosis and treatment of interstitial lung disease |
| DE602004008658T2 (de) * | 2003-09-05 | 2008-06-12 | Cellzome Ag | Behandlung neurodegenerativer krankheiten |
| WO2005023858A1 (en) * | 2003-09-05 | 2005-03-17 | Cellzome Ag | Protein complexes associated with app-processing |
| EP2369348A1 (en) * | 2003-11-07 | 2011-09-28 | Ciphergen Biosystems, Inc. | Biomarkers for Alzheimer's disease |
| CA2549160A1 (en) | 2003-12-04 | 2005-06-23 | The Scripps Research Institute | Treatment and preventions of asthma |
| KR100992492B1 (ko) | 2004-04-05 | 2010-11-08 | 토쿠시마 대학 | 국소 점막 면역 유도 촉진용 항원약물 비히클, 이것을 사용하는 점막 백신, 알레르기의 예방제 또는 치료제, 약물전달 시스템, 및 점막면역의 유도방법 |
| JP2008546701A (ja) * | 2005-06-14 | 2008-12-25 | イェシバ・ユニバーシティ | Aβ産生へのBRI蛋白の効果 |
| WO2007005672A2 (en) | 2005-06-30 | 2007-01-11 | The Scripps Research Institute | Treatment and prevention of respiratory diseases and conditions |
| CN101257919B (zh) | 2005-08-05 | 2012-08-29 | 国立大学法人德岛大学 | 可以由选择性产生IgA抗体向产生IgA和IgG两种抗体转换的抗原药物载体和使用该载体的经鼻·粘膜疫苗 |
| JP4981305B2 (ja) | 2005-11-11 | 2012-07-18 | 公益財団法人大阪バイオサイエンス研究所 | アルツハイマー病の発症リスク又はアルツハイマー病発症予後の予測方法 |
| EP2096910A4 (en) * | 2006-11-22 | 2011-11-30 | Einstein Coll Med | Transgenic mammals modified bri protein expression |
| CN101754747A (zh) | 2007-06-05 | 2010-06-23 | Paka肺部医药公司 | 用于向肺脏递送药物的方法以及组合物 |
| WO2009009396A2 (en) | 2007-07-06 | 2009-01-15 | Mayo Foundation For Medical Education And Research | Bri polypeptides and reducing ab aggregation |
| WO2010087771A1 (en) | 2009-01-30 | 2010-08-05 | Alphabeta Ab | Compound and method for treatment of alzheimer's disease |
| JP5339387B2 (ja) | 2009-08-10 | 2013-11-13 | 独立行政法人科学技術振興機構 | オートファジーの測定方法 |
| AU2010356144B2 (en) * | 2010-06-24 | 2015-06-04 | Alphabeta Ab | Compound and method for treatment of Alzheimer's disease and familial dementia |
-
2012
- 2012-03-30 EP EP12721004.5A patent/EP2694977B1/en not_active Not-in-force
- 2012-03-30 JP JP2014503629A patent/JP6227523B2/ja not_active Expired - Fee Related
- 2012-03-30 WO PCT/SE2012/050352 patent/WO2012138284A1/en not_active Ceased
- 2012-03-30 US US14/009,360 patent/US9522170B2/en not_active Expired - Fee Related
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