JP2014516407A5 - - Google Patents

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Publication number
JP2014516407A5
JP2014516407A5 JP2014503629A JP2014503629A JP2014516407A5 JP 2014516407 A5 JP2014516407 A5 JP 2014516407A5 JP 2014503629 A JP2014503629 A JP 2014503629A JP 2014503629 A JP2014503629 A JP 2014503629A JP 2014516407 A5 JP2014516407 A5 JP 2014516407A5
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JP
Japan
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seq
derived
human
protein
condition
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JP2014503629A
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English (en)
Japanese (ja)
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JP6227523B2 (ja
JP2014516407A (ja
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Priority claimed from PCT/SE2012/050352 external-priority patent/WO2012138284A1/en
Publication of JP2014516407A publication Critical patent/JP2014516407A/ja
Publication of JP2014516407A5 publication Critical patent/JP2014516407A5/ja
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Publication of JP6227523B2 publication Critical patent/JP6227523B2/ja
Expired - Fee Related legal-status Critical Current
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JP2014503629A 2011-04-05 2012-03-30 治療の方法においておよび化合物のスクリーニングのために有用なアミロドーシスターゲット Expired - Fee Related JP6227523B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1150299 2011-04-05
SE1150299-4 2011-04-05
PCT/SE2012/050352 WO2012138284A1 (en) 2011-04-05 2012-03-30 Amyloidosis target useful in methods of treatment and for screening of compounds

Publications (3)

Publication Number Publication Date
JP2014516407A JP2014516407A (ja) 2014-07-10
JP2014516407A5 true JP2014516407A5 (enExample) 2015-05-14
JP6227523B2 JP6227523B2 (ja) 2017-11-08

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ID=46085122

Family Applications (1)

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JP2014503629A Expired - Fee Related JP6227523B2 (ja) 2011-04-05 2012-03-30 治療の方法においておよび化合物のスクリーニングのために有用なアミロドーシスターゲット

Country Status (4)

Country Link
US (1) US9522170B2 (enExample)
EP (1) EP2694977B1 (enExample)
JP (1) JP6227523B2 (enExample)
WO (1) WO2012138284A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102300582A (zh) 2009-01-30 2011-12-28 阿尔法贝塔公司 用于治疗阿尔茨海默病的化合物和方法
CA3054370A1 (en) * 2017-02-24 2018-08-30 Alzheon, Inc. Methods for treating neurodegenerative disorders
CN115943153A (zh) * 2020-01-08 2023-04-07 阿尔法贝塔公司 用于治疗阿尔茨海默病的化合物和方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988003170A1 (en) 1986-10-24 1988-05-05 Whitsett Jeffrey A Pulmonary hydrophobic surfactant-associated proteins
WO2000026251A2 (en) 1998-10-30 2000-05-11 Holtzman Jordan L A COMPLEX OF A CHAPERONE WITH ss-AMYLOID AND METHODS EMPLOYING THIS COMPLEX
WO2000071671A2 (en) * 1999-05-26 2000-11-30 New York University New mutant genes in familial british dementia and familial danish dementia
US20030224982A1 (en) 2001-07-05 2003-12-04 Li Li Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US6673545B2 (en) 2000-07-28 2004-01-06 Incyte Corporation Prostate cancer markers
US6716589B2 (en) 2000-11-20 2004-04-06 Alphabeta Ab Discordant helix stabilization for prevention of amyloid formation
US20040235813A1 (en) * 2001-05-03 2004-11-25 Erich Wanker Compounds that inhibit hsp90 and stimulate hsp70 and hsp40, useful in the prevention or treatment of diseases associated with protein aggregation and amyloid formation
NZ536796A (en) 2002-04-25 2007-03-30 Scripps Research Inst Treatment and prevention of pulmonary conditions comprising at least one lung surfactant polypeptide and at least one protease inhibitor, lipase inhibitor or an anti-oxidant
CN100401896C (zh) 2002-12-09 2008-07-16 儿童医院医疗中心 诊断和治疗间质性肺病的方法
US20060216292A1 (en) * 2003-09-05 2006-09-28 Cellzome Ag Treatment of neurodegenerative diseases
WO2005023858A1 (en) * 2003-09-05 2005-03-17 Cellzome Ag Protein complexes associated with app-processing
US7794948B2 (en) * 2003-11-07 2010-09-14 Vermilllion, Inc. Biomarkers for alzheimer's disease
AU2004296206A1 (en) 2003-12-04 2005-06-23 The Scripps Research Institute Treatment and preventions of asthma
JP4843792B2 (ja) 2004-04-05 2011-12-21 国立大学法人徳島大学 経粘膜及び経皮投与を可能にする抗原薬物ヴィークル、これを用いる粘膜免疫の誘導方法、粘膜ワクチン及びｄｄｓ
US20100098682A1 (en) * 2005-06-14 2010-04-22 D Adamio Luciano Effect of Bri Proteins on Ass Production
WO2007005672A2 (en) 2005-06-30 2007-01-11 The Scripps Research Institute Treatment and prevention of respiratory diseases and conditions
EP1930025B1 (en) 2005-08-05 2013-05-01 The University of Tokushima ANTIGEN-AND-DRUG VEHICLE WHICH ENABLES THE CHANGEOVER FROM THE SELECTIVE PRODUCTION OF IgA ANTIBODY TO THE PRODUCTION OF BOTH OF IgA AND IgG ANTIBODIES, AND TRANSNASAL/TRANSMUCOSAL VACCINE USING THE VEHICLE
JP4981305B2 (ja) 2005-11-11 2012-07-18 公益財団法人大阪バイオサイエンス研究所 アルツハイマー病の発症リスク又はアルツハイマー病発症予後の予測方法
US20110055936A1 (en) * 2006-11-22 2011-03-03 D Adamio Luciano Transgenic mamals modifield in bri protein expression
AU2008259768B2 (en) 2007-06-05 2013-08-29 Paka Pulmonary Pharmaceuticals, Inc. Compositions for delivering medicaments into the lungs, uses thereof
US20100298202A1 (en) 2007-07-06 2010-11-25 Mayo Foundation For Medical Education And Research Bri polypeptides and reducing ab aggregation
CN102300582A (zh) 2009-01-30 2011-12-28 阿尔法贝塔公司 用于治疗阿尔茨海默病的化合物和方法
EP2466294B1 (en) 2009-08-10 2014-07-23 Japan Science And Technology Agency Method for measuring autophagy
AU2010356144B2 (en) * 2010-06-24 2015-06-04 Alphabeta Ab Compound and method for treatment of Alzheimer's disease and familial dementia

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