JP2014516407A5 - - Google Patents

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Publication number
JP2014516407A5
JP2014516407A5 JP2014503629A JP2014503629A JP2014516407A5 JP 2014516407 A5 JP2014516407 A5 JP 2014516407A5 JP 2014503629 A JP2014503629 A JP 2014503629A JP 2014503629 A JP2014503629 A JP 2014503629A JP 2014516407 A5 JP2014516407 A5 JP 2014516407A5
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JP
Japan
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seq
derived
human
protein
condition
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JP2014503629A
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English (en)
Japanese (ja)
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JP6227523B2 (ja
JP2014516407A (ja
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Priority claimed from PCT/SE2012/050352 external-priority patent/WO2012138284A1/en
Publication of JP2014516407A publication Critical patent/JP2014516407A/ja
Publication of JP2014516407A5 publication Critical patent/JP2014516407A5/ja
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Publication of JP6227523B2 publication Critical patent/JP6227523B2/ja
Expired - Fee Related legal-status Critical Current
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JP2014503629A 2011-04-05 2012-03-30 治療の方法においておよび化合物のスクリーニングのために有用なアミロドーシスターゲット Expired - Fee Related JP6227523B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE1150299-4 2011-04-05
SE1150299 2011-04-05
PCT/SE2012/050352 WO2012138284A1 (en) 2011-04-05 2012-03-30 Amyloidosis target useful in methods of treatment and for screening of compounds

Publications (3)

Publication Number Publication Date
JP2014516407A JP2014516407A (ja) 2014-07-10
JP2014516407A5 true JP2014516407A5 (enExample) 2015-05-14
JP6227523B2 JP6227523B2 (ja) 2017-11-08

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ID=46085122

Family Applications (1)

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JP2014503629A Expired - Fee Related JP6227523B2 (ja) 2011-04-05 2012-03-30 治療の方法においておよび化合物のスクリーニングのために有用なアミロドーシスターゲット

Country Status (4)

Country Link
US (1) US9522170B2 (enExample)
EP (1) EP2694977B1 (enExample)
JP (1) JP6227523B2 (enExample)
WO (1) WO2012138284A1 (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010087771A1 (en) 2009-01-30 2010-08-05 Alphabeta Ab Compound and method for treatment of alzheimer's disease
US11077095B2 (en) * 2017-02-24 2021-08-03 Alzheon, Inc. Methods for treating neurodegenerative disorders
JP7820821B2 (ja) * 2020-01-08 2026-02-26 アルファベータ・エービー アルツハイマー病の治療のための化合物及び方法

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0290516A4 (en) 1986-10-24 1989-11-14 Jeffrey A Whitsett PROTEINS RELATED TO SURFACE-EFFECTIVE HYDROPHOBIC LUNG ACTIVE SUBSTANCES.
ATE284538T1 (de) 1998-10-30 2004-12-15 Jordan L Holtzman Komplex, bestehend aus einem chaperon und beta- amyloidprotein sowie verfahren, die diesen komplex benutzen
US6670195B1 (en) * 1999-05-26 2003-12-30 New York University Mutant genes in Familial British Dementia and Familial Danish Dementia
US20030224982A1 (en) 2001-07-05 2003-12-04 Li Li Therapeutic polypeptides, nucleic acids encoding same, and methods of use
US6673545B2 (en) 2000-07-28 2004-01-06 Incyte Corporation Prostate cancer markers
US6716589B2 (en) 2000-11-20 2004-04-06 Alphabeta Ab Discordant helix stabilization for prevention of amyloid formation
EP1387678A1 (en) * 2001-05-03 2004-02-11 Max-Planck-Gesellschaft Zur Förderung Der Wissenschaften E.V. Compounds that inhibit hsp90 and stimulate hsp70 and hsp40, useful in the prevention or treatment of diseases associated with protein aggregation and amyloid formation
MXPA04010560A (es) 2002-04-25 2005-08-15 Scripps Research Inst Tratamiento y prevencion de condiciones pulmonares.
CA2507613A1 (en) 2002-12-09 2004-07-08 Jeffrey A. Whitsett Methods of diagnosis and treatment of interstitial lung disease
DE602004008658T2 (de) * 2003-09-05 2008-06-12 Cellzome Ag Behandlung neurodegenerativer krankheiten
WO2005023858A1 (en) * 2003-09-05 2005-03-17 Cellzome Ag Protein complexes associated with app-processing
EP2369348A1 (en) * 2003-11-07 2011-09-28 Ciphergen Biosystems, Inc. Biomarkers for Alzheimer's disease
CA2549160A1 (en) 2003-12-04 2005-06-23 The Scripps Research Institute Treatment and preventions of asthma
KR100992492B1 (ko) 2004-04-05 2010-11-08 토쿠시마 대학 국소 점막 면역 유도 촉진용 항원약물 비히클, 이것을 사용하는 점막 백신, 알레르기의 예방제 또는 치료제, 약물전달 시스템, 및 점막면역의 유도방법
JP2008546701A (ja) * 2005-06-14 2008-12-25 イェシバ・ユニバーシティ Aβ産生へのBRI蛋白の効果
WO2007005672A2 (en) 2005-06-30 2007-01-11 The Scripps Research Institute Treatment and prevention of respiratory diseases and conditions
CN101257919B (zh) 2005-08-05 2012-08-29 国立大学法人德岛大学 可以由选择性产生IgA抗体向产生IgA和IgG两种抗体转换的抗原药物载体和使用该载体的经鼻·粘膜疫苗
JP4981305B2 (ja) 2005-11-11 2012-07-18 公益財団法人大阪バイオサイエンス研究所 アルツハイマー病の発症リスク又はアルツハイマー病発症予後の予測方法
EP2096910A4 (en) * 2006-11-22 2011-11-30 Einstein Coll Med Transgenic mammals modified bri protein expression
CN101754747A (zh) 2007-06-05 2010-06-23 Paka肺部医药公司 用于向肺脏递送药物的方法以及组合物
WO2009009396A2 (en) 2007-07-06 2009-01-15 Mayo Foundation For Medical Education And Research Bri polypeptides and reducing ab aggregation
WO2010087771A1 (en) 2009-01-30 2010-08-05 Alphabeta Ab Compound and method for treatment of alzheimer's disease
JP5339387B2 (ja) 2009-08-10 2013-11-13 独立行政法人科学技術振興機構 オートファジーの測定方法
AU2010356144B2 (en) * 2010-06-24 2015-06-04 Alphabeta Ab Compound and method for treatment of Alzheimer's disease and familial dementia

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